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The many faces of sarcoidosis: Radiology © WASOG: educational material

The many faces of sarcoidosis: Radiology - WASOG faces of... · HRCT images of a sarcoidosis patient A: mediastinal setting; enlarged mediastinal lymph nodes, LN=3 (1 ) B: parenchymal

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Page 1: The many faces of sarcoidosis: Radiology - WASOG faces of... · HRCT images of a sarcoidosis patient A: mediastinal setting; enlarged mediastinal lymph nodes, LN=3 (1 ) B: parenchymal

The many faces of sarcoidosis: Radiology

© WASOG: educational material

Page 2: The many faces of sarcoidosis: Radiology - WASOG faces of... · HRCT images of a sarcoidosis patient A: mediastinal setting; enlarged mediastinal lymph nodes, LN=3 (1 ) B: parenchymal

Chest radiographic stages in sarcoidosis

stage I

stage II stage IV

stage III

© WASOG

Page 3: The many faces of sarcoidosis: Radiology - WASOG faces of... · HRCT images of a sarcoidosis patient A: mediastinal setting; enlarged mediastinal lymph nodes, LN=3 (1 ) B: parenchymal

Sarcoidosis Chest X-ray stage I

© WASOG

Page 4: The many faces of sarcoidosis: Radiology - WASOG faces of... · HRCT images of a sarcoidosis patient A: mediastinal setting; enlarged mediastinal lymph nodes, LN=3 (1 ) B: parenchymal

Sarcoidosis Chest X-ray stage I

© WASOG

Page 5: The many faces of sarcoidosis: Radiology - WASOG faces of... · HRCT images of a sarcoidosis patient A: mediastinal setting; enlarged mediastinal lymph nodes, LN=3 (1 ) B: parenchymal

Sarcoidosis Chest X-ray stage II

© WASOG

Page 6: The many faces of sarcoidosis: Radiology - WASOG faces of... · HRCT images of a sarcoidosis patient A: mediastinal setting; enlarged mediastinal lymph nodes, LN=3 (1 ) B: parenchymal

Sarcoidosis Chest X-ray stage III

© WASOG

Page 7: The many faces of sarcoidosis: Radiology - WASOG faces of... · HRCT images of a sarcoidosis patient A: mediastinal setting; enlarged mediastinal lymph nodes, LN=3 (1 ) B: parenchymal

Sarcoidosis Chest X-ray stage IV

© WASOG

Page 8: The many faces of sarcoidosis: Radiology - WASOG faces of... · HRCT images of a sarcoidosis patient A: mediastinal setting; enlarged mediastinal lymph nodes, LN=3 (1 ) B: parenchymal

Visual HRCT score in sarcoidosisadapted from Oberstein et al. (1997)

Eur Radiology 2003; 13: 2462-71.

BVB: thickening or irregularity

of the bronchovascular bundle

PL: pleural

thickening

PC: parenchymal

consolidations

LN: lymph node

enlargement1.LS: septal lines

2.BVB

ND: intraparenchymal

nodules

© WASOG

Page 9: The many faces of sarcoidosis: Radiology - WASOG faces of... · HRCT images of a sarcoidosis patient A: mediastinal setting; enlarged mediastinal lymph nodes, LN=3 (1 ) B: parenchymal

HRCT images of a sarcoidosis patient

A: mediastinal setting; enlarged

mediastinal lymph nodes, LN=3 (1)

B: parenchymal consolidations, PC=1 (1)

thickening or irregularity of the

bronchovascular bundle, BVB=2 (2)

C: septal lines, LS=2 (1)

BVB=2 (2)D: focal pleural thickening, PL=1 (1),

intraparenchymal nodules, ND=2 (2) © WASOG

Page 10: The many faces of sarcoidosis: Radiology - WASOG faces of... · HRCT images of a sarcoidosis patient A: mediastinal setting; enlarged mediastinal lymph nodes, LN=3 (1 ) B: parenchymal

Chest X-ray PET/CT

CXR stage IV

Sarcoidosis patient with inflammation

© WASOG

Page 11: The many faces of sarcoidosis: Radiology - WASOG faces of... · HRCT images of a sarcoidosis patient A: mediastinal setting; enlarged mediastinal lymph nodes, LN=3 (1 ) B: parenchymal

Case: 38-year-old woman

before MTX after MTX

Treatment MTX 12.5 mg once a week subcutaneous

folic acid 5 mg twice a week

prednisone 7.5 mg daily orally© WASOG

Page 12: The many faces of sarcoidosis: Radiology - WASOG faces of... · HRCT images of a sarcoidosis patient A: mediastinal setting; enlarged mediastinal lymph nodes, LN=3 (1 ) B: parenchymal

Case: 36-year-old man

TreatmentMTX 12.5 mg once a week orally

Folic acid 5 mg once a week

Prednisone 10 mg daily

HRCT before MTX HRCT after 6 months MTX

© WASOG

Page 13: The many faces of sarcoidosis: Radiology - WASOG faces of... · HRCT images of a sarcoidosis patient A: mediastinal setting; enlarged mediastinal lymph nodes, LN=3 (1 ) B: parenchymal

WASOG

World

Association for

Sarcoidosis and

Other

Granulomatous Disorders

www.wasog.org

Join us: become a member!