ThirdPeriodicReview

Dissemina(onandtrainingac(vi(esEdwinMorley-Fletcher-WP18

Brussels,12thMay2016

Dissemina(onObjec(vesofY3

Allforecastedobjec?veshavebeenachieved:•  Dissemina(onobjects:sixvideo-clipshavebeencreatedand

uploadedonMD-Paedigree’sYoutubechannel•  Ac?vepar(cipa(oninmajordissemina(onevents:

•  Exhibi?on Booth and a Networking Session within the ICT2015conferenceinLisbon

•  SpeakersCorneratehealthWeekinRiga•  Variousothernetworkingevents,especiallyinrela?ontoBigDatainhealth.

•  TheannualNewsleKer(specialissue4-5)waspublished,andisavailableonline,aspdftobedownloaded,andonprintedversion.

•  D18.3Trainingeventwas?melysubmiUedonM30.

Brussels,12thMay2016

Dissemina(onObjects

•  Sixvideo-clipsintendedtopresentinaconcisewaytheMD-Paedigree’sareas.

•  All relevant partners were involved in thecrea?onofthevariousvideoclips

Brussels,12thMay2016

ICT2015(1)

•  MD-Paedigree took part in “ICT 2015: Innovate,Connect, Transform: 20th -22nd October 2015,Lisbon”, with a booth jointly organized incoopera?onwithGÉANTandCardioproof

Brussels,12thMay2016

ICT2015(2)

•  Theboothwas visitedbyCommissionerCarlosMoedas andthe Portugues Minister of Educa(on and Science NunoCrato.

Brussels,12thMay2016

OurpresenceatICT2015(3)

MD-PaedigreealsohadaNetworkingSessionwhereadiscussionpaper on “Enhanced Consent: a vision for Pa?ent DataProtec?onandDataManagement”wassuccessfullypresented.

Brussels,12thMay2016

md-paedigree.eu

Regularlyupdatedandop?mised:•  Anewvideosec?onwascreated,embeddingthevideospublishedontheYouTubechannel.

•  New banners were designed for thehomepage

•  AcookieconsentmodulewasimplementedincompliancewiththeEC’slatestguidelines

Brussels,12thMay2016

md-paedigree.eu(2)

Brussels,12thMay2016

•  The website is regularly visited, with 57,8% of online sessionsfromnewvisitorsfromallovertheworld

•  In total, around 3,000 sessions were recorded onmd-paedigree.eu from March 2015 to February 2016, withaltogetherover8,000pageviews.

SocialMedia

•  Asocialnetworkstrategyhasbeenimplementedtoreinforcepublicoutreach.

•  MD-Paedigree’sTwiUeraccounthasbeenregularlyupdatedandcountsnowaround100followers(with24,000tweetvisualisa(ons,2,000profilevisits,and100men(ons).

•  Successfulinterac?onshavetakenplacewitheHealth-andBigDatainhealthcare-relatedaccounts.

Brussels,12thMay2016

Seminars,WorkshopsandConcerta(onAc(vi(es(1)•  WorkshoponClinicalDataManagementandSustainability(inconcerta?onVPH-ShareandpMedicine),

March17-18th2015,Barcelona(Spain)•  E-healthweek2015(WoHIT/HIMSS),11th-13thMay2015,Riga(Latvia):SpeakersCorner•  Bio-Techno-Prac?ceWorkshopon“InSilicoMedicine:philosophicalfounda?onsandbiomedical

applica?ons”,June3rd,2015,Barcelona(Spain)•  HIMSSPrivacy&SecurityForum,29June-1July2015,Chicago-Ill.(USA)•  RDA(ResearchDataAlliance)6thPlenarySession,23rdSeptember2015Paris(France)•  ENISAAnnualPrivacyForum,8thOctober2015,Luxembourg:Invita?ontoEdwinMorley-Fletcherto

aUendasspeakerthePanelonBigData•  ICT2015,MD-PaedigreejointboothwithGéantandCardioproof,20th-22ndOctober2015,Lisbon

(Portugal).JointboothwithCardioproofandGéant,NetworkingSessiononPa?entDataPrivacyandEnhancedConsent.

•  EuropeanDataForum,16th-17thNovember2015,Luxembourg•  ECround-tableonpersonalinforma?onmanagement,27thNovember2015,Brussels(Belgium)•  RDA7°PlenarySession,29thFebruary-3rdMarch,2016–Tokyo(Japan):Dedicatedpresenta?onforthe

proposalofa‘HealthData’IntrerestGroup.

Brussels,12thMay2016

Seminars,WorkshopsandConcerta(onAc(vi(es(2)

•  24thEuromircoInterna?onalConferenceonParallel,Distributed,andNetwork-BasedProcessing,HeraklionCrete,Greece,2016.

•  E-healthday,June11th2015,Sierre,Switzerland•  19thIEEEHighPerformanceExtremeCompu?ngConference,

Waltham,MA,USA,Sept.15-17,2015•  37thAnnualInter.Conf.oftheIEEEEngineeringinMedicine&

BiologySociety-EMBC2015,Milano,August25th-29th,2015•  Func%onalImagingandModelingoftheHeart,8thInterna?onal

Conference,FIMH2015,Maastricht,TheNetherlands,June2015•  STACOM2015(Sta?s?calAtlasesandComputa?onalModelsofthe

Heart.ImagingandModellingChallenges)workshop,MunichGermany,Sept2015

•  MICCAI2015(MedicalImageCompu?ngandComputer-AssistedInterven?on)conference,Munich,Germany,Sept2015

Brussels–6-7May2014

Listofpublica(onsforyear3(1)

•  Noninvasivehemodynamicassessment,treatmentoutcomepredic(onandfollow-upofaor(ccoarcta(onfromMRimaging.RalovichK,ItuL,VitanovskiD,SharmaP,IonasecR,MihalefV,KrawtschukW,ZhengY,EvereUA,PongiglioneG,LeonardiB,RingelR,NavabN,HeimannT,ComaniciuD.MedPhys.2015May

•  GutMicrobiotaDysbiosisasRiskandPremorbidFactorsofIBDandIBSAlongtheChildhood–AdulthoodTransi(on,LorenzaPu?gnani,FedericaDelChierico,PamelaVernocchi,MicheleCicala,SalvatoreCucchiara,andBrunoDallapiccola.DysbiotrackStudyGroup,InflammBowelDis2015

•  Applyingmachinelearningtogaitanalysisdatafordiseaseiden(fica(on.JoyseereeR,AbouSabhaR,MuellerH.StudHealthTechnolInform.2015.

•  APa(ent-SpecificFootModelfortheEs(mateofAnkleJointForcesinPa(entswithJuvenileIdiopathicArthri(s.PrinoldJA,MazzàC,DiMarcoR,HannahI,MalaqaC,Magni-ManzoniS,PetrarcaM,RoncheqAB,TanturrideHora?oL,vanDijkhuizenEH,WesargS,Vicecon?M;MD-PAEDIGREEConsor?um.AnnBiomedEng.2016Jan

•  Delinea(ngtheapplica(onofultrasoundindetec(ngsynovialabnormali(esofsubtalarjointinjuvenileidiopathicarthri(s.LanniS,BovisF,RavelliA,ViolaS,MagnaguagnoF,PistorioA,MagnanoGM,Mar?niA,MalaqaC.Arthri?sCareRes(Hoboken).2016Jan27

•  Expertconsensusondynamicsoflaboratorytestsfordiagnosisofmacrophageac(va(onsyndromecomplica(ngsystemicjuvenileidiopathicarthri(s.A.Mar?nietal.RMDOpen.2016Jan19;2(1):e000161.doi:10.1136/rmdopen-2015-000161.eCollec?on2016.

•  Revieweracknowledgement2015.Mar?niA,SpencerC.PediatrRheumatolOnlineJ.2016Feb1•  Rela(onsbetweenmuscleenduranceandsubjec(velyreportedfa(gue,walkingcapacity,and

par(cipa(oninmildlyaffectedadolescentswithcerebralpalsy.EkenMM,HoudijkH,DoorenboschCA,KiezebrinkFE,vanBennekomCA,HarlaarJ,DallmeijerAJ.DevMedChildNeurol.2016Feb24.

Brussels,12thMay2016

Listofpublica(onsforyear3(2)

•  EnergyBalance-RelatedBehaviors,Perinatal,Sociodemographic,andParentalRiskFactorsAssociatedwithObesityinItalianPreschoolers.ShashajB,GrazianiMP,ContoliB,CiuffoC,CivesC,FaccioliniS,RigoniML,SpaternaS,TaucciM,RaponiM,MancoM.JAmCollNutr.2016Mar2

•  Autoimmunedisease-associatedgeneexpressionisreducedbyBET-inhibi(on.PeetersJG,VervoortSJ,MijnheerG,deRoockS,VastertSJ,NieuwenhuisEE,vanWijkF,PrakkenBJ,MokryM,vanLoosdregtGenomData.2015Nov7;7:14-7.doi:10.1016/j.gdata.2015.11.004.eCollec?on2016Mar.

•  Diseaseac(vityaccountsforlong-termefficacyofIL-1blockersinpyogenicsterilearthri(spyodermagangrenosumandsevereacnesyndrome.OmeneqA,CartaS,CaorsiR,FineqM,MaroUoD,LaUanziB,JoriniM,DelfinoL,PencoF,PiccoP,BuoncompagniA,Mar?niA,RubartelliA,GaUornoM.Rheumatology(Oxford).2016Mar17

•  2016Classifica(onCriteriaforMacrophageAc(va(onSyndromeComplica(ngSystemicJuvenileIdiopathicArthri(s:AEuropeanLeagueAgainstRheuma(sm/AmericanCollegeofRheumatology/PaediatricRheumatologyInterna(onalTrialsOrganisa(onCollabora(veIni(a(ve.A.Mar?nietal.AnnRheumDis.2016Mar

•  GutmicrobiotaprofilingofpediatricNAFLDandobesepa(entsunveiledbyanintegratedmeta-omicsbasedapproach.DelChiericoF,NobiliV,VernocchiP,RussoA,DeStefanisC,GnaniD,FurlanelloC,ZandonàA,PaciP,CapuaniG,DallapiccolaB,MiccheliA,AlisiA,Pu?gnaniL.Hepatology.2016Mar29

•  APa(ent-SpecificFootModelfortheEs(mateofAnkleJointForcesinPa(entswithJuvenileIdiopathicArthri(s.Prinold,J.I.,Mazzà,C.,DiMarco,R.,Hannah,I.,Malaqa,C.,Magni-Manzoni,S.,Petrarca,M.,Roncheq,A.,TanturrideHora?o,L.,vanDijkhuizen,E.H.P.,Wesarg,S.andVicecon?,M.,2016.Annalsofbiomedicalengineering44,247-257.

•  ComprehensiveAssessmentoftheGlobalandRegionalVascularResponsestoFoodInges(oninHumansUsingNovelRapidMRI.JAHauser,VMuthurangu,JASteeden,AMTaylor,AJones.AmericanJournalofPhysiology-Regulatory,Integra?veandCompara?vePhysiology.Jan201610.1152/ajpregu.00454.2015

Brussels,12thMay2016

Listofpublica(onsforyear3(3)

•  AcceleratedVisualConceptDetec(onUsingSteerableRieszWavelets,AnamariaVizi?u,LucianItu,RanveerJoyseeree,AdrienDepeursinge,HenningMüllerandConstan?nSuciu,GPU-,ConferenceonParallel,Distributed,andNetwork-BasedProcessing,Heraklion,Greece,2016.

•  ADemoofMul(modalMedicalRetrieval,RanveerJoyseeree,RogerSchaer,HenningMüller,WorkshoponContent-basedMul?mediaIndexing(CBMI),Bucharest,Romania,2016.

•  Loca(ngseedpointsformul(-organautoma(csegmenta(onusingnon-rigidregistra(onandorganannota(ons,RanveerJoyseeree,HenningMüller,,SPIEMedicalImaging,2015.

•  Iden(fyingthepathologyclassofpa(entsusingonlytheirgaitanalysisdatawiththeaidofmachinelearning,RanveerJoyseeree,RamiAbouSabha,HenningMüller,MIE2015,Madrid,Spain,2015.

•  Combina(onofPolyaffineTransforma(onsandSupervisedLearningfortheAutoma(cDiagnosisofLVInfarct,Marc-MichelRohé,NicolasDuchateau,MaximeSermesant,XavierPennec.ProcofSTACOM2015(Sta?s?calAtlasesandComputa?onalModelsoftheHeart.ImagingandModellingChallenges),LNCSVol9534,pp.190-198,January2016.

•  ANon-parametricSta(s(calShapeModelforAssessmentoftheSurgicallyRepairedAor(cArchinCoarcta(onoftheAorta:HowNormalisAbnormal?.JLBruse,KMcleod,GBiglino,HNNtsinjana,CCapelli,TYHsia,MSermesant,XPennec,ATaylor,andSSchievano.ProcofSTACOM2015(Sta?s?calAtlasesandComputa?onalModelsoftheHeart.ImagingandModellingChallenges),LNCSVol9534,pp.21-29,January2016

•  Descrip(veandIntui(vePopula(on-BasedCardiacMo(onAnalysisviaSparsityConstrainedTensorDecomposi(on.KMcleod,MSermesant,PBeerbaum,andXPennec.ProcofMICCAI2015(MedicalImageCompu?ngandComputer-AssistedInterven?on),LNCSVol.9351,pp419-426,2015.

•  Propaga(onofMyocardialFibreArchitectureUncertaintyonElectromechanicalModelParameterEs(ma(on:ACaseStudy.RMolléro,DNeumann,MMRohé,MDatar,HLombaert,NAyache,DComaniciu,OEcabert,MChinali,GRinelli,XPennec,MSermesant,andTMansi.ProcofFIMH2015(Func?onalImagingandModelingoftheHeart),LNCSVol.9126,pp448-456,2015

Brussels–6-7May2014

Trainingteam

Brussels–May12th2016

Developers Trainingteam Endusers

Aims:•  Toassistend-userswiththeuseofMD-Paedigree’sInfostructure.•  Toassistwiththedevelopmentoftheplawormbasedonusers’needsObjec?ves:•  Toworkcloselywithbothend-usersandplaworm(soxware)developers.•  Allcomments,concernsandissuestobeunderstoodandrespondedto.

Trainingteam

Brussels–May29th2015

Importanttomen?on:•  Originalscopeoftrainingac?vityhasbeensignificantlyexpanded:

-  Moretrainingsessionsthanoriginallyplanned-  MoreInterac?onswithbothdevelopersandend-users

OngoingTasks:Suppor?ngbothendsby•  Gatheringconcerns/issuesviamee?ngs,anonymousques?onnaires,etc.•  One-to-onetutorials•  Dailymonitoringtheplawormandrepor?ngerrors/issues•  Arrangingagilesessionswiththedevelopers•  Providinguser-friendlytutorialsFutureplans:•  Mul?pleexampleswillbeuploadedontheplawormtoassistendusers(videos)•  Addi?onaltrainingsessionwillbeannounced

ThreeMee?ngssofar:Utrecht

Brussels–May12th2016

Asession(September2014)wascommencedinUtrechtwhichcoveredGeneraltaskssuchas•  Crea?ngaccounts•  Cohortbrowser•  Similaritysearch•  Querywizard,managementandvisualisa?on•  Filesharing•  Ques?onnairewasgivenAxerthesession,theques?onnaireswereassessedandreviewedbyboththetraining teamand thedevelopers; thus,both concernsand sugges?onswereaddressedandimplementedwherenecessary.

ThreeMee?ngssofar:Crete

Brussels–May12th2016

Amee?ngwasheldinCrete(October2015)whichcoveredseveraldemosoneachtools;•  Case based retrieval (CBR): The demo showed the possible state of the plaworm

whereinthePCDRdatawasmainlyexplored.

•  Datacura?onandvalida?on(DCV):ThedemoshowedhowtolookthroughthedatasetsandcorrectanypossibleerrorsorhaveabeUervisualisa?onoverthedata

•  Dataanonymiser(byGnubila): thedemoillustratedhowtoeliminatethepa?entsiden?fyingdata(Suchasnameaddress,etc)

•  CaseReasoner:Showedaninterac?veroutetofindsimilari?esamongpa?entsIn the end, the users provided feedback on the demos shown. The comments wereassessedandaddressedpriortothenexttrainingevent.

ThreeMee?ngssoFar:Rome

Brussels–May12th2016

February2016Ahands-on training sessionwasperformed inRomewhichcovered themainaims and objec?ves of each tool with the goal ofhelping the users to startexploringandusingeachtool.Casebasedretrieval(CBR):Ø  Theservicehelpsphysicianstofindsimilarpa?entsbasedonthedischarge

synthesisofagivenpa?ent.Ø  Theserviceproposesasummaryofthereturnedcasesofsimilarpa?entsat

differentpointsin?me.

Details:Romemee?ng

Brussels–May12th2016

Datacura?onandvalida?on(DCV):Ø  Anautoma?cdatacleaningprocessØ  TotroubleshoottheimporteddataØ  Todetectnumericaloutliers,missingvalues,alphanumerictypographicaland

logicalerrors.

Details:Romemee?ng

Brussels–May12th2016

CaseReasoner:Ø  CaseReasonerisaflexibleandinterac?vetoolthatprovidesdecision

supportthroughsimilaritysearch.Ø  Currently,itistarge?ngtheCardiovascularDiseaseRiskinObeseChildren

andAdolescentsdiseasegroupØ  Todoasimilaritysearchwithinpa?entsØ  Tovisualisetheir3Dgeometryi.e.heart

Details:Romemee?ng

Brussels–May12th2016

CaSiReView:Ø  Tobrowseandvisualisethesimula?onresults.Ø  Browsemodelingresultsforallpa?entsØ  InspectLVvolumesØ  InspectLVpressuresØ  InspectLVEFØ  InspectLVSVØ  InspectcardiacmovementoveraheartcycleØ  Toreportpoten?alissuesØ  Analysecohortsta?s?cs

Lessonslearnt

Brussels–May12th2016

Ø  Commentsandconcernswerediscussedduringthetrainingsessions

Ø Someofthecommentswereimmediatelyaddressedduringthetrainingsessions

Ø Thefeedbackwasanalysedthoroughly,andwasaddressedanddealtwith

Ø Sugges?onsfromtheenduserswereimplementedØ Themostcurrent/updatedversionofeachtoolwillbeonlineandreadytoaccess

Ø Thefutureversionwillincludeallthecomments,concernsandsugges?onsdiscussedduringthehands-ontrainingsessions