E. Be&en, R. Pothnann, lJ. Niederberger, U. Plump, G. Rlaibnch, and R. Grcis Mp to 12 ger cent of schoolchildren suffer fpom mlgranne. Symotomatlc trea~~nt ipith Qatn medleatlon 1s often Ineffective OP causes side effects.Thereforeproohyla~ls can be useful. Irp to now there are very few mvestrgatlons about the effectsof prophylactic therapy in migrainesufferers. Our study tries to verify the effect of a new beta-blocker drug II-I children. In a double-blind p~aceba-controlled design the an beta -selective beta-blocker ~etopro~Ql UET; Oelo was comparedto Uiby~r~r~etam~~e (DHE).The studyconr~sted of four Dhases:baseline (4 weeks). placebo (5 w&s). therapy(10 weeks) and follow-up (4 weeks). Untilnow 21 cRildren. aged 8-14, participated In the study.They were recruited from the neuroQed)atrlc clinic. I diagnosed them by IHS crlterla.13 children had common or elasslc migraine, 8 children had mlxed (migraine end tension-type) headache. The parameters of mlgralne(attaekfrequency, duration.lntenslty etc.1 were recordedby a diary that the childrenand their Dafentsbad to fill in during the whole study period.The ehlldrcnhad to take tlielr medlcatlon once, a day in the evening; the dose was dependent on the children's werght. The first bat8 suggestthat both Qraphylactlc agents reduce the frequency of mlgralntl BttW.5, but MItCQQrolo~ 15 more efft)CtlVe (8 reducEIon by MET, 64% by WE.) Dy treating wth MetoQro~ol there IS also a greatar decrease III Qaln duration and InCBfl5lty. As enpected the rned~catlon had no effect on tenslen headache @QiSodes some of the children were suffering fram. itio 2, 3, 3, 5. 6, 6. 16 ycarr) rologlcal problema recaivrd du elw hat;ehrss pare In ttw dwiar1om bslew thr ~11 had I(IWZ~ Ji glrbreee); two had QMiCtaClti - 3 childron recclwd P.N. ni - 3 childrsn ~mc~~v~dP.N. ni

Treatment of preadolescent chronic headaches using relaxation- and stress-management procedures

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Page 1: Treatment of preadolescent chronic headaches using relaxation- and stress-management procedures

E. Be&en, R. Pothnann, lJ. Niederberger, U. Plump, G. Rlaibnch, and R. Grcis

Mp to 12 ger cent of schoolchildren suffer fpom mlgranne. Symotomatlc trea~~nt ipith Qatn medleatlon 1s often Ineffective OP causes side effects. Therefore proohyla~ls can be useful. Irp to now there are very few mvestrgatlons about the effects of prophylactic therapy in migraine sufferers. Our study tries to verify the effect of a new beta-blocker drug II-I children. In a double-blind p~aceba-controlled design the an beta -selective beta-blocker ~etopro~Ql UET; Oelo was compared to Uiby~r~r~etam~~e (DHE). The study conr~sted of four Dhases: baseline (4 weeks). placebo (5 w&s). therapy (10 weeks) and follow-up (4 weeks). Until now 21 cRildren. aged 8-14, participated In the study. They were recruited from the neuroQed)atrlc clinic. I diagnosed them by IHS crlterla. 13 children had common or elasslc migraine, 8 children had mlxed (migraine end tension-type) headache. The parameters of mlgralne (attaek frequency, duration. lntenslty etc.1 were recorded by a diary that the children and their Dafents bad to fill in during the whole study period. The ehlldrcn had to take tlielr medlcatlon once, a day in the evening; the dose was dependent on the children's werght. The first bat8 suggest that both Qraphylactlc agents reduce the frequency of mlgralntl BttW.5, but MItCQQrolo~ 15 more efft)CtlVe (8 reducEIon by MET, 64% by WE.) Dy treating wth MetoQro~ol there IS also a greatar decrease III Qaln duration and InCBfl5lty. As enpected the rned~catlon had no effect on tenslen headache @QiSodes some of the children were suffering fram.

itio

2, 3, 3, 5. 6, 6. 16 ycarr) rologlcal problema recaivrd

du elw hat; ehrss pare In ttw

dwiar1om bslew thr ~11 had I(IWZ~ Ji

glrbreee); two had QMiCtaClti - 3 childron recclwd P.N. ni - 3 childrsn ~mc~~v~d P.N. ni