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  • 1. Tropical Medicine Graduate ProgramGraduate Student HandbookRevised July, 2008 Department of Tropical Medicine, Medical Microbiology &PharmacologyJohn A. Burns School of Medicine University of Hawai`i at Manoa651 Ilalo StreetHonolulu, HI 96813Phone (808) 692-1600 Fax (808) 692-1979 1

2. Revised July, 2008Table of Contents Description of Department, Graduate Program & Faculty . 3Student LearningOutcomes 5Student Assessment 6Requiredand Recommended Courses 10Graduate Program Requirements 12Academic Policies 16Tropical MedicineCourse Descriptions 16Useful Links 19UH Manoa Campus Map 20 2 3. Revised July, 2008 Map to John A. Burns School of Medicine (Kaka`ako Campus) 22Graduate Faculty Description & Contact Information 233 4. Revised July, 2008 Description of the Department, Graduate Program & FacultyTropical Medicine is the study of diseases that occur more commonly in the tropical regions of the world. However, in todays era of globalization and modern transportation, diseases that were once confined to the tropics have spread geographically and now play a significant role in the 20th century global resurgence of infectious diseases. As such, research in the area of tropical medicine and medical microbiology has greatly increased in importance in the past 20 years. The Department of Tropical Medicine, Medical Microbiology, and Pharmacology, at the John A. Burns School of Medicine, University of Hawaii at Manoa (UHM) offers graduate programs leading to the MS and PhD in Biomedical Sciences (Tropical Medicine). A major goal of the department is to provide Asian and Pacific countries the expertise needed to conduct tropical infectious diseases research. Tropical medicine faculty conduct studies on infectious organisms and the diseases they cause, including dengue, West Nile, AIDS, hepatitis, viral and bacterial encephalitis, malaria, tuberculosis and Kawasaki disease. The faculty employs a multidisciplinary approach, including immunology, pathogenesis, epidemiology, pharmacology, diagnosis, prevention, control, treatment, socio-ecological systems, human ecology, microbial and vector ecology, environmental change, and participatory action research to answer fundamental questions associated with the transmission dynamics and pathogenesis of these diseases. These studies can be laboratory-based, field-based, clinic-based, or include a combination of all three.The field of tropical medicine requires knowledge of virology, bacteriology, parasitology, entomology, immunology, cell and molecular biology, epidemiology, ecology, behavioral science and clinical medicine. In this respect, the tropical medicine program at UHM provides learning opportunities in a range of biological disciplines available in few other university departments. Students also receive vigorous training in scientific methodology. The department has active research programs with several community hospitals and collaborates closely with the State of Hawai`i Department of Health, providing instruction and expertise in bioterrorism preparedness and diagnosis of infectious diseases using the latest technology. In addition to local collaborations, department faculty have partnered with several international institutions in Southeast Asia and Africa specializing in infectious disease research.Faculty *Graduate Faculty*D. J. Gubler, ScD (Chair)arboviruses and vector-borne disease, epidemiology and control *S. N. Bennett, PhDmolecular evolution and epidemiology of emerging infectious 4 5. Revised July, 2008 diseases *S. P. Chang, PhDimmunology, molecular biology, malaria vaccine development A. Collier, PhD pharmacology, pharmacokinetics, reproductive pharmacology C. B. Cropp, MSarbovirology *A. R. Diwan, PhDmedical virology, chemotherapy, vaccines (retired) *E. Furusawa, MD, PhDviral chemotherapy (retired) L. Gollin, PhDmedical anthropology and ethnobotany *W. L. Gosnell, PhDhost parasite interactions, malaria, immunology *G. S. N. Hui, PhDparasitology, immunology, cell biology P. H. Kaufusi - pathogenesis of West Nile virus *K. J. Kramer, PhDparasitology, epidemiology, leptospirosis, HIV serodiagnosis H. Luo, PhD pathogenesis of arboviruses and polyomaviruses *F. D. Miller, PhDepidemiology of infectious diseases *V. R. Nerurkar, PhDpathogenesis of infectious diseases, delineating cellular and molecular mechanisms underlying microbe-host interaction *D. W. Taylor, Ph.D. - malaria immunology, maternal and child health *S. Verma, PhDmolecular, biochemical aspects of viral diseases G. Watt, MDzoonotic infectious diseases *B. A. Wilcox, PhDecology of infectious diseases, integrative health research, community medicine *S. Verma, PhDdiagnosis of Kawasaki syndrome, effect of selenium deficiency on RNA virus mutations *K. Yamaga, PhDimmunological mechanisms of diseasesCooperating Graduate Faculty J. M. Berestecky, PhDenteric bacteria G. Erdem, MDmolecular epidemiology of group A streptococcal and staphylococcal infections; complications of strep infections like acute rheumatic fever A. Imrie, PhDcytotoxic T-cells & HIV J. H. Kim, MDHIV viral neutralization, cytokine gene therapy in HIV specific T-cells, HTLV-I and-II mechanisms of Rex protein function S. R. Kim, PhDbasic immunology of HIV-1 infection Y. Lu, PhD gene transfer and gene therapy in HIV-infection, diagnostic virology M. E. Melish, MDstaphylococcal infection and toxins, clinical infectious disease, Kawasaki syndrome F. D. Pien, MDclinical microbiology, diagnostic bacteriology and parasitology, efficacy of antimicrobial agents R. C. Rudoy, MDclinical aspects of viral and bacterial diseases B. Shiramizu, MDpathobiology of HIV-associated disorders E. K. Tam, MDinflammation, immunologic mechanisms of pulmonary diseases, genetic and environmental determinants of asthma R. Yanagihara, MDemerging and re-emerging infectious diseases Q. Yu, MD,PhD HIV-1 vaccines and memory CTL responses 5 6. Revised July, 2008 Affiliate Graduate Faculty F. Mercier, PhD neurovirology C. F. T. Uyehara, PhDdevelopmental and cardiovascular pharmacologyAdministrative Staff Sheila Kawamoto, Administrative & Fiscal Support Specialist Karen Amii, Clerk StenographerTropical Medicine Graduate Program Student Learning OutcomesA. Master of Science in Biomedical Sciences (Tropical Medicine)1. Demonstrate a fundamental knowledge base in the major subdisciples ofthe field of Tropical Medicine: bacteriology, virology, mycology,parasitology, immunology, molecular epidemiology, and infectiousdisease ecology.2. Demonstrate a mastery of technical and experimental methodologiesrequired to conduct research in the field of Tropical Medicine.3. Demonstrate the ability to plan, execute, interpret, and evaluateexperimental studies in Tropical Medicine.4. Demonstrate skills required for instruction, assessment and mentoring ofundergraduate and MS level students.5. Demonstrate proficiency in written and verbal communication skills inclassroom lectures and other teaching formats and in professionalseminars and presentations.6. Demonstrate sufficient mastery and scientific maturity to assess the workof peers in related fields.B. Ph.D. in Biomedical Sciences (Tropical Medicine)1.Demonstrate an advanced knowledge base in the major subdisciples of the field of Tropical Medicine: bacteriology, virology, mycology, parasitology, immunology, molecular epidemiology, and infectious disease ecology.2.Demonstrate a mastery of technical and experimental methodologies required to conduct research in the field of Tropical Medicine.6 7. Revised July, 2008 3.Demonstrate the ability to plan, execute, interpret, and evaluate experimental studies in Tropical Medicine.4.Demonstrate skills for instruction, assessment and mentoring of undergraduate, MS and PhD level students.5.Demonstrate skills to verbally communicate scientific concepts and results in classroom lectures and other teaching formats and in professional seminars and presentations.6.Demonstrate written communication skills as required in various professional duties including manuscript preparation for scientific publication, preparation of research grant applications, preparation of lecture notes, development of introductory and advanced courses in related disciplines.7.Demonstrate sufficient mastery and scientific maturity to assess the work of peers in related fields.8.Develop administrative skills to manage a research laboratory, supervise technical and professional staff, and assume responsibilities and provide leadership as a faculty member. Tropical Medicine Graduate Program Student Assessment A. Master of Science Degree 1. Course evaluationsa. Core courses: written examinations at regular intervals (midtermexams) as well as a final examination at the end of the courseb. Advanced courses: written exams may be substituted by termpapers or oral presentations on a subject selected by student andthe faculty instructorc. Course examinations, papers and presentations are evaluated bythe faculty instructor 2. Diagnostic evaluationa. First or second semester of residenceb. Written exam to evaluate background in infectious diseasemicrobiology & immunologyc. Used to advise on course of study 3. Master's Plan A (Thesis)a. Thesis proposal is evaluated and subject to approval by thesisadvisory committeeb. General (Qualifying) Examination7 8. Revised July, 2008 A general examination (written and oral) will be required before a student is advanced to candidacy for a Master of Science degree. The examination will be given during the third or fourth semester of residence. The questions will be composed by the graduate faculty and will be designed to adequately test the student's basic knowledge of the fields of biomedical sciences and Tropical Medicine. The results of the oral/written examination will be used to evaluate the student's progress and to advise him/her on a course of study to correct any weakness. A student who passes the examination may be r

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