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Università degli Studi di Perugia

Dipartimento di MEDICINA

Sezione GERONTOLOGIA E GERIATRIA

Coordinatore: Prof.ssa Patrizia MECOCCI

e-mail: patrizia.mecocci@unipg.it Tel.: 075 578 3270 Segreteria:

Tel.: 075 578 3839 Fax: 075 578 3878 e-mail: clinica.geriatrica@unipg.it

Pubblicazioni selezionate (2011-2016): 1. Delirium Day": A nationwide point prevalence study of delirium in older hospitalized patients using an easy standardized diagnostic tool.

Bellelli, Giuseppe; Morandi, Alessandro; Di Santo, Simona G.; Mazzone, Andrea; Cherubini, Antonio; Mossello, Enrico; Bo, Mario; Bianchetti, Angelo; Rozzini, Renzo; Zanetti, Ermellina; Musicco, Massimo; Ferrari, Alberto; Ferrara, Nicola; Trabucchi, Marco; Boffelli, Stefano; Stefano, Fabio Di; Filippi, Francesco De; Guerini, Fabio; Bertoletti, Erik; March, Albert; Margiotta, Alessandro; Mecocci, Patrizia; Addesi, Desireè; Fantò, Fausto; Dijik, Babette; Porrino, Paola; Cotroneo, Antonino Maria; Galli, Giovanni; Bruni, Amalia Cecilia; Bernardini, Bruno; Corsini, Carla; Cagnin, Annachiara; Zurlo, Amedeo; Barbagallo, Giuseppe; Lunardelli, Maria Lia; Martini, Emilio; Battaglia, Giuseppe; Latella, Raffaele; Petritola, Donatella; Sinforiani, Elena; Cester, Alberto; Formilan, Marino; Carbone, Pasqualina; Appollonio, Ildebrando; Cereda, Diletta; Tremolizzo, Lucio; Bottacchi, Edo; Lucchetti, Lucio; Mariani, Claudio; Rapazzini, Piero; Romanelli, Giuseppe; Marengoni, Alessandra; Zuliani, Giovanni; Bianchi, Lara; Suardi, Teresa; Muti, Ettore; Bottura, Renato; Sgrò, Giovanni; Mandas, Antonella; Serchisu, Luca; Crippa, Patrizia; Ivaldi, Claudio; Ungar, Andrea; Villani, Daniele; Raimondi, Clara; Mussi, Chiara; Isaia, Giancarlo; Provenzano, Giuseppe; Mari, Daniela; Odetti, Patrizio; Monacelli, Fiammetta; Incalzi, Raffaele Antonelli; Pluderi, Alice; Bellamoli, Claudio; Terranova, Luciano; Scarpini, Elio; D'Amico, Ferdinando; Cavallini, Maria Chiara; Guerrini, Gianbattista; Scotuzzi, Anna Maria; Chiarello, Antonino; Pilotto, Alberto; Tognini, Sara; Dell'Aquila, Giuseppina; Toigo, Gabriele; Ceschia, Giuliano; Piccinini, Maristella; Fabbo, Andrea; Zoli, Marco; Forti, Paola; Wenter, Christian; Basile, Giorgio; Lasagni, Anna; Padovani, Alessandro; Rozzini, Luca; Cottino, Maria; Vitali, Silvia; Tripi, Gabriele; Avanzi, Stefano; Annoni, Giorgio; Ruotolo, Giovanni; Boschi, Federica; Bonino, Paolo; Marchionni, Niccolo; Fascendini, Sara; Noro, Gabriele; Turco, Renato; Ubezio, Maria C.; Serrati, Carlo; Infante, Maria; Gentile, Simona; Pernigotti, Luigi M.; Biagini, Carlo A.; Canonico, Enzo; Bonati, Pietro; Gareri, Pietro; Caffarra, Paolo; Ceretti, Arcangelo; Castiglia, Rosanna; Gabelli, Carlo; Storto, Mario Lo; Putzu, Paolo; Santo, Simona Di. BMC MEDICINE. 2016; 14 (1) 106-

2. “Oldest old” man with odynophagia and generalized asthenia: It could be tetanus! Boccardi, Virginia; Cupido, Maria Grazia; Ruggiero,

Carmelinda; Aisa, Giovanni; Ercolani, Sara; Zampi, Ivano; Mecocci, Patrizia. GERIATRICS AND GERONTOLOGY INTERNATIONAL. 2016; 16 (7) 885-887

3. A novel Alzheimer disease locus located near the gene encoding tau protein. Jun, G; Ibrahim-Verbaas, Ca; Vronskaya, M; Lambert, Jc; Chung, J; Naj, Ac; Kunkle, Bw; Wang, Ls; Bis, Jc; Bellenguez, C; Harold, D; Farrar, La; Mecocci, P; Rubinsztein, Dc; Lovestone, S; Bayer, A; Gallacher, J; Proitsi, P; Ortega-Cubero, S (over 300 authors). MOLECULAR PSYCHIATRY. 2016; 21 () 108-117

4. A Pathway Based Classification Method for Analyzing Gene Expression for Alzheimer's disease Diagnosis. Voyle, N; Keohane, A; Newhouse, S; Lunnon, K; Johnston, C; Soininen, H; Kloszewska, I; Mecocci, P; Tsolaki, M; Vellas, B; Hodges, A; Kiddle, S; Dobson, Rj. JOURNAL OF ALZHEIMER'S DISEASE. 2016; 49 () 659-669

5. A Validation Study of Vascular Cognitive Impairment Genetics Meta-Analysis Findings in an Independent Collaborative Cohort. Skrobot, O.A.; Mcknight, A.J.; Passmore, P.A.; Seripa, D.; Mecocci, P.; Panza, F.; Kalaria, R.; Wilcock, G.; Munafo, M.; Erkinjuntti, T.; Karhunen, P.; Pessi, T.; Martiskainen, M.; Love, S.; Kehoe, P.G.. JOURNAL OF ALZHEIMER'S DISEASE. 2016; 53 (3) 981-989

6. Bone Mineral Density and Cognitive Decline in Elderly Women: Results from the InCHIANTI Study. Laudisio, Alice; Fontana, Davide Onofrio; Rivera, Chiara; Ruggiero, Carmelinda; Bandinelli, Stefania; Gemma, Antonella; Ferrucci, Luigi; Antonelli Incalzi, Raffaele. CALCIFIED TISSUE INTERNATIONAL. 2016; 98 (5) 479-488

7. Diagnostic Assessment and Management of Dysphagia in Patients with Alzheimer's disease. Boccardi, Virginia; Ruggiero,

Carmelinda; Patriti, Alberto; Marano, Luigi. JOURNAL OF ALZHEIMER'S DISEASE. 2016; 50 (4) 947-955 8. Differential diagnosis of neurodegenerative diseases using structural MRI data. Koikkalainen, Juha; Rhodius-Meester, Hanneke;

Tolonen, Antti; Barkhof, Frederik; Tijms, Betty; Lemstra, Afina W.; Tong, Tong; Guerrero, Ricardo; Schuh, Andreas; Ledig, Christian; Rueckert, Daniel; Soininen, Hilkka; Remes, Anne M.; Waldemar, Gunhild; Hasselbalch, Steen; Mecocci, Patrizia; Van Der Flier, Wiesje; Lötjönen, Jyrki. NEUROIMAGE. CLINICAL. 2016; 11 () 435-449

9. Disrupted Network Topology in Patients with Stable and Progressive Mild Cognitive Impairment and Alzheimer's disease. Pereira Joana, B; Mijalkov, Mite; Kakaei, Ehsan; Mecocci, Patrizia; Vellas, Bruno; Tsolaki, Magda; Kłoszewska, Iwona; Soininen, Hilka; Spenger, Christian; Lovestone, Simmon; Simmons, Andrew; Wahlund, Lars-Olof; Volpe, Giovanni; Westman, Eric. CEREBRAL CORTEX. 2016; 26 (8) 3476-3493

10. Fatigue as a clinical sign of biological aging: Exploratory analyses from the MINDED project. Zengarini, Elisa; Ruggiero, Carmelinda; Mecocci, Patrizia; Vellas, Bruno; Cesari, Matteo. GERIATRICS AND GERONTOLOGY INTERNATIONAL. 2016; 16 (4) 533-534

11. Genetic influences on schizophrenia and subcortical brain volumes: Large-scale proof of concept. Franke B, Stein JL, Ripke S, Anttila V, Hibar DP, van Hulzen KJ, Arias-Vasquez A, Smoller JW, Nichols TE, Neale MC, McIntosh AM, Lee P, McMahon FJ, Meyer-Lindenberg A, Mattheisen M, Andreassen OA, Gruber O, Sachdev PS, Roiz-Santiañez R, Saykin AJ, Ehrlich S, Mather KA, Turner JA, Schwarz E, Thalamuthu A, Yao Y, Ho YY, Martin NG, Wright MJ; O'Donovan MC, Thompson PM, Neale BM, Medland SE, Sullivan PF, Adolfsson R, Blackwood DH, Børglum AD, Bramon E, Buxbaum JD, Cichon S, Darvasi A, Domenici E, Ehrenreich H, Esko T,Gejman PV, Gill M, Gurling H, Hultman CM, Iwata N, Jablensky AV, Jönsson EG, Kendler KS, Kirov G, Knight J, Lencz T,

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Levinson DF, Li QS, Liu J, Malhotra AK, McCarroll SA, McQuillin A, Moran JL, Mortensen PB, Mowry BJ, Nöthen MM, Ophoff RA, Owen MJ, Palotie A, Pato CN, Petryshen TL, Posthuma D, Rietschel M, Riley BP, Rujescu D, Sham PC, Sklar P, St Clair D, Weinberger DR, Wendland JR, Werge T, Daly MJ, Renteria ME, , Desrivières S, Jahanshad N, Toro R, Wittfeld K, Abramovic L, Andersson M, Aribisala BS, Armstrong NJ, Bernard M, Bohlken MM, Boks MP, Bralten J, Brown AA, Chakravarty MM, Chen Q, Ching CR, Cuellar-Partida G, den Braber A, Giddaluru S, Goldman AL, Grimm O, Guadalupe T, Hass J, Woldehawariat G, Holmes AJ, Hoogman M, Janowitz D, Jia T, Kim S, Klein M, Kraemer B, Loohuis LM, Luciano M, Macare C, Milaneschi Y, Nho K, Papmeyer M, Ramasamy A, Risacher SL, Rose EJ, Salami A, Sämann PG, Schmaal L, Schork AJ, Shin J, Strike LT, Teumer A, van Donkelaar MM, van Eijk KR,Walters RK, Westlye LT, Whelan CD, Winkler AM, Zwiers MP, Alhusaini S, Athanasiu L, Hakobjan MM, Hartberg CB, Haukvik U, Heister AJ, Höhn D, Kasperaviciute D, Liewald DC, Lopez LM, Makkinje RR, Matarin M, Naber MA, McKay DR, Needham M, Nugent AC, Pütz B, Royle NA,Shen L, Sprooten E, Trabzuni D, van der Marel SS, Walton E, Wolf C, Almasy L, Ames D, Arepalli S, Assareh AA, Bastin ME,Brodaty H, Bulayeva KB, Carless MA, Cichon S, Corvin A, Curran JE, Czisch M, de Zubicaray GI, Dillman A, Duggirala R, Dyer TD, Erk S, Fedko IO, Ferrucci L, Foroud TM, Fox PT, Fukunaga M, Gibbs R, Göring HH, Green RC, Guelfi S, Hansell NK, Hartman CA, Hegenscheid K, Heinz A,Hernandez DG, Heslenfeld DJ, Hoekstra PJ, Holsboer F, Homuth G, Hottenga JJ, Ikeda M, Jack CR, Jenkinson M, Johnson R, Kanai R, Keil M,Kent JW, Kochunov P, Kwok JB, Lawrie SM, Liu X, Longo DL, McMahon KL, Meisenzahl E, Melle I, Mohnke S, Montgomery GW, Mostert JC,Mühleisen TW, Nalls MA, Nilsson LG, Nöthen MM, Ohi K, Olvera RL, Perez-Iglesias R, Pike GB, Potkin SG, Reinvang I, Reppermund S, Rietschel M, Romanczuk-Seiferth N, Rosen GD, Rujescu D, Schnell K, Schofield PR, Smith C, Steen VM, Sussmann JE, Toga AW, Traynor B, Troncoso J, Hernández MC, Ent Dv, van der Brug M, van der Wee NJ, van Tol MJ, Veltman DJ, Wassink TH, Westman E, Zielke RH, Zonderman A, Ashbrook DG, Hager R, Lu L, Morris DW, Williams RW, Brunner HG, Buckner RL, Buitelaar JK, Cahn W,Calhoun VD, Cavalleri GL, Crespo-Facorro B, Dale AM, Davies GE, Delanty N, Depondt C, Djurovic S, Drevets WC, Espeseth T, Gollub RL, Ho BC, Hoffmann W, Hosten N, Kahn RS, LeHellard S, Müller-Myhsok B, Nauck M, Nyberg L, Pandolfo M, Penninx BW, Roffman JL, Sisodiya SM, van Bokhoven H, van Haren NE, Völzke H, Walter H, Weiner MW, Wen W, White T, Agartz I, Blangero J, Boomsma DI, Brouwer RM, Cannon DM, Cookson MR, de Geus EJ, Deary IJ, Donohoe G, Fernández G, Fisher SE, Francks C, Glahn DC, Grabe HJ, Hardy J, Hashimoto R, Hulshoff Pol HE, Jönsson EG, Kloszewska I, Lovestone S, Mattay VS, Mecocci P, McDonald C, Ophoff RA, Paus T, Pausova Z, Ryten M, Simmons A, Singleton A, Soininen H, Wardlaw JM, Weale ME, Weinberger DR, Adams HH, Launer LJ, Seiler S, Schmidt R, Chauhan G, Satizabal CL, Becker JT, Yanek L, van der Lee SJ, Ebling M, Fischl B, Longstreth WT, Greve D, Schmidt H, Nyquist P, Vinke LN, van Duijn CM, Luting X, Mazoyer B, Bis JC, Gudnason V, Seshadri S, Ikram MA, Schumann G. NATURE NEUROSCIENCE. 2016; 19 (3) 420-431

12. Inappropriate prescription of low molecular weight heparins for thromboprophylaxis among older hospitalized patients. Garasto, Sabrina; Fusco, Sergio; Onder, Graziano; Sganga, Federica; Mammarella, Federica; Volpato, Stefano; Ruggiero, Carmelinda; Abbatecola, Angela M.; Lattanzio, Fabrizia; Corsonello, Andrea. AGING CLINICAL AND EXPERIMENTAL RESEARCH. 2016; () 1-8

13. Inappropriate use of proton pump inhibitors in elderly patients discharged from acute care hospitals. Schepisi, R.; Fusco, Sergio; Sganga, F.; Falcone, B.; Vetrano, D.L.; Abbatecola, A.; Corica, F.; Maggio, M.; Ruggiero, C.; Fabbietti, P.; Corsonello, A.; Onder, G.; Lattanzio, F. THE JOURNAL OF NUTRITION, HEALTH & AGING. 2016; 20 (6) 665-670

14. Lack of Energy and Negative Health-Related Outcomes in Nursing Home Residents: Results From the INCUR Study. Zengarini, Elisa; Hoogendijk, Emiel O.; Pérez-Zepeda, Mario U.; Ruggiero, Carmelinda; Mecocci, Patrizia; Vellas, Bruno; Cesari, Matteo. JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2016; 17 (6) 525-529

15. Measuring global brain atrophy with the brain volume/cerebrospinal fluid index: Normative values, cut-offs and clinical associations. Orellana, Camila; Ferreira, Daniel; Muehlboeck, J.-Sebastian; Mecocci, Patrizia; Vellas, Bruno; Tsolaki, Magda; Kłoszewska, Iwona; Soininen, Hilkka; Lovestone, Simon; Simmons, Andrew; Wahlund, Lars-Olof; Westman, Eric. NEURODEGENERATIVE DISEASES. 2016; 16 (1-2) 77-86

16. Physical activity and inflammation: Effects on gray-matter volume and cognitive decline in aging. Papenberg, G.; Ferencz, B.; Mangialasche, F.; Mecocci, P.; Cecchetti, R.; Kalpouzos, G.; Fratiglioni, L.; Backman, L. HUMAN BRAIN MAPPING. 2016; 37 (10) 3462-3473

17. Quantitative validation of a visual rating scale for frontal atrophy: associations with clinical status, APOE e4, CSF biomarkers and cognition. Ferreira, Daniel; Cavallin, Lena; Granberg, Tobias; Lindberg, Olof; Aguilar, Carlos; Mecocci, Patrizia; Vellas, Bruno; Tsolaki, Magda; Kłoszewska, Iwona; Soininen, Hilkka; Lovestone, Simon; Simmons, Andrew; Wahlund, Lars-Olof; Westman, Eric. EUROPEAN RADIOLOGY. 2016; 26 (8) 2597-2610

18. The clock-drawing test as a screening tool in mild cognitive impairment and very mild dementia: a new brief method of scoring and normative data in the elderly. Ricci, M.; Pigliautile, M.; D'Ambrosio, V.; Ercolani, S.; Bianchini, C.; Ruggiero, C.; Vanacore, N.; Mecocci, P. NEUROLOGICAL SCIENCES. 2016; 37 (6) 867-873

19. The Effect of Age Correction on Multivariate Classification in Alzheimer's disease, with a Focus on the Characteristics of Incorrectly and Correctly Classified Subjects. Falahati, F; Ferreira, D; Soininen, H; Mecocci, P; Vellas, B; Tsolaki, M; Kłoszewska, I; Lovestone, S; Eriksdotter, M; Wahlund, Lo; Simmons, A; Westman, E. BRAIN TOPOGRAPHY. 2016; 29 () 296-307

20. The effect of increased genetic risk for Alzheimer's disease on hippocampal and amygdala volume. Lupton, Michelle K; Strike, Lachlan; Hansell, Narelle K.; Wen, Wei; Mather, Karen A.; Armstrong, Nicola J.; Thalamuthu, Anbupalam; Mcmahon, Katie L.; de Zubicaray, Greig I.; Assareh, Amelia A.; Simmons, Andrew; Proitsi, Petroula; Powell, John F.; Montgomery, Grant W.; Hibar, Derrek P.; Westman, Eric; Tsolaki, Magda; Kloszewska, Iwona; Soininen, Hilkka; Mecocci, Patrizia; Velas, Bruno; Lovestone, Simon; Brodaty, Henry; Ames, David; Trollor, Julian N.; Martin, Nicholas G.; Thompson, Paul M.; Sachdev, Perminder S.; Wright, Margaret J.. NEUROBIOLOGY OF AGING. 2016; 40 () 68-77

21. Underdiagnosis and undertreatment of nursing home residents at high risk for fragility fractures. Ruggiero, C.; Baroni, M.; Zengarini, E.; Dell’Aquila, G.; Cherubini, A.; Boccardi, V.; Lattanzio, F.; Mecocci, P. JNHR. 2016; 2 () 57-63

22. Validation of chronic obstructive pulmonary disease (COPD) diagnoses in healthcare databases: A systematic review protocol. Rimland, Joseph M; Abraha, Iosief; Luchetta, Maria Laura; Cozzolino, Francesco; Orso, Massimiliano; Cherubini, Antonio; Dell'Aquila, Giuseppina; Chiatti, Carlos; Ambrosio, Giuseppe; Montedori, Alessandro. BMJ OPEN. 2016; 6 (6) e011777-

23. Anticholinergic drugs and negative outcomes in the older population: from biological plausibility to clinical evidence. Collamati, A; Martone, Am; Poscia, A; Brandi, V; Celi, M; Marzetti, E; Cherubini, A; Landi, F. AGING CLINICAL AND EXPERIMENTAL RESEARCH. 2015; () -

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24. Association of habitual dietary resveratrol exposure with the development of frailty in older age: the Invecchiare in Chianti study. Rabassa, M; Zamora-Ros, R; Urpi-Sarda, M; Bandinelli, S; Ferrucci, L; Andres-Lacueva, C; Cherubini, A. THE AMERICAN JOURNAL OF CLINICAL NUTRITION. 2015; () -

25. Association of increased carotid intima-media thickness and lower plasma levels of vitamin C and vitamin E in old age subjects: implications for Alzheimer's disease. Polidori, Mc; Ruggiero, C; Croce, Mf; Raichi, T; Mangialasche, F; Cecchetti, R; Pelini, L; Paolacci, L; Ercolani, S; Mecocci, P. JOURNAL OF NEURAL TRANSMISSION. 2015; 122 (4) 523-530

26. Automated Hippocampal Subfield Measures as Predictors of Conversion from Mild Cognitive Impairment to Alzheimer's disease in Two Independent Cohorts. Khan W, Westman E; Jones, N; Wahlund, Lo; Mecocci, P; Vellas, B; Tsolaki, M; Kłoszewska, I; Soininen, H; Spenger, C; Lovestone, S; Muehlboeck, Js; Simmons, A; For, the AddNeuroMed consortium; For, the Alzheimer’s Disease Neuroimaging Initiative. BRAIN TOPOGRAPHY. 2015; 28 () 746-759

27. Circulating Proteomic Signatures of Chronological Age. Menni C; Kiddle SJ; Mangino M; Viñuela A; Psatha M; Steves C; Sattlecker M; Buil A; Newhouse S; Nelson S; Williams S; Voyle N; Soininen H; Kloszewska I; Mecocci P; Tsolaki M; Vellas B; Lovestone S; Spector TD; Dobson R; Valdes AM.. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2015; 70 () 809-816

28. Common genetic variants influence human subcortical brain structures. Hibar DP, Stein JL; Renteria, Me; Arias-Vasquez, A; Desrivières, S; Jahanshad, N; Toro, R; Wittfeld, K; Abramovic, L; Andersson, M; Aribisala, Bs; Armstrong, Nj; Bernard, M; Bohlken, Mm; Boks, Mp; Bralten, J; Brown, Aa; Mallar Chakravarty, M; Chen, Q; Ching, Cr; Cuellar-Partida, G; den Braber, A; Giddaluru, S; Goldman, Al; Grimm, O; Guadalupe, T; Hass, J; Woldehawariat, G; Holmes, Aj; Hoogman, M; Janowitz, D; Jia, T; Kim, S; Klein, M; Kraemer, B; Lee, Ph; Olde Loohuis, Lm; Luciano, M; Macare, C; Mather, Ka; Mattheisen, M; Milaneschi, Y; Nho, K; Papmeyer, M; Ramasamy, A; Risacher, Sl; Roiz-Santiañez, R; Rose, Ej; Salami, A; Sämann, Pg; Schmaal, L; Schork, Aj; Shin, J; Strike, Lt; Teumer, A; van Donkelaar, Mm; van Eijk, Kr; Walters, Rk; Westlye, Lt; Whelan, Cd; Winkler, Am; Zwiers, Mp; Alhusaini, S; Athanasiu, L; Ehrlich, S; Hakobjan, Mm; Hartberg, Cb; Haukvik, Uk; Heister, Aj; Hoehn, D; Kasperaviciute, D; Liewald, Dc; Lopez, Lm; Makkinje, Rr; Matarin, M; Naber, Ma; Reese McKay, D; Needham, M; Nugent, Ac; Pütz, B; Royle, Na; Shen, L; Sprooten, E; Trabzuni, D; van der Marel, Ss; van Hulzen, Kj; Walton, E; Wolf, C; Almasy, L; Ames, D; Arepalli, S; Assareh, Aa; Bastin, Me; Brodaty, H; Bulayeva, Kb; Carless, Ma; Cichon, S; Corvin, A; Curran, Je; Czisch, M; de Zubicaray, Gi; Dillman, A; Duggirala, R; Dyer, Td; Erk, S; Fedko, Io; Ferrucci, L; Foroud, Tm; Fox, Pt; Fukunaga, M; Raphael Gibbs, J; Göring, Hh; Green, Rc; Guelfi, S; Hansell, Nk; Hartman, Ca; Hegenscheid, K; Heinz, A; Hernandez, Dg; Heslenfeld, Dj; Hoekstra, Pj; Holsboer, F; Homuth, G; Hottenga, Jj; Ikeda, M; Jr, Jack CR; Jenkinson, M; Johnson, R; Kanai, R; Keil, M; Jr, Kent JW; Kochunov, P; Kwok, Jb; Lawrie, Sm; Liu, X; Longo, Dl; Mcmahon, Kl; Meisenzahl, E; Melle, I; Mohnke, S; Montgomery, Gw; Mostert, Jc; Mühleisen, Tw; Nalls, Ma; Nichols, Te; Nilsson, Lg; Nöthen, Mm; Ohi, K; Olvera, Rl; Perez-Iglesias, R; Bruce Pike, G; Potkin, Sg; Reinvang, I; Reppermund, S; Rietschel, M; Romanczuk-Seiferth, N; Rosen, Gd; Rujescu, D; Schnell, K; Schofield, Pr; Smith, C; Steen, Vm; Sussmann, Je; Thalamuthu, A; Toga, Aw; Traynor, Bj; Troncoso, J; Turner, Ja; Valdés Hernández, Mc; van 't Ent, D; van der Brug, M; van der Wee, Nj; van Tol, Mj; Veltman, Dj; Wassink, Th; Westman, E; Zielke, Rh; Zonderman, Ab; Ashbrook, Dg; Hager, R; Lu, L; Mcmahon, Fj; Morris, Dw; Williams, Rw; Brunner, Hg; Buckner, Rl; Buitelaar, Jk; Cahn, W; Calhoun, Vd; Cavalleri, Gl; Crespo-Facorro, B; Dale, Am; Davies, Ge; Delanty, N; Depondt, C; Djurovic, S; Drevets, Wc; Espeseth, T; Gollub, Rl; Ho, Bc; Hoffmann, W; Hosten, N; Kahn, Rs; Le Hellard, S; Meyer-Lindenberg, A; Müller-Myhsok, B; Nauck, M; Nyberg, L; Pandolfo, M; Penninx, Bw; Roffman, Jl; Sisodiya, Sm; Smoller, Jw; van Bokhoven, H; van Haren, Ne; Völzke, H; Walter, H; Weiner, Mw; Wen, W; White, T; Agartz, I; Andreassen, Oa; Blangero, J; Boomsma, Di; Brouwer, Rm; Cannon, Dm; Cookson, Mr; de Geus, Ej; Deary, Ij; Donohoe, G; Fernández, G; Fisher, Se; Francks, C; Glahn, Dc; Grabe, Hj; Gruber, O; Hardy, J; Hashimoto, R; Hulshoff Pol, He; Jönsson, Eg; Kloszewska, I; Lovestone, S; Mattay, Vs; Mecocci, P; Mcdonald, C; Mcintosh, Am; Ophoff, Ra; Paus, T; Pausova, Z; Ryten, M; Sachdev, Ps; Saykin, Aj; Simmons, A; Singleton, A; Soininen, H; Wardlaw, Jm; Weale, Me; Weinberger, Dr; Adams, Hh; Launer, Lj; Seiler, S; Schmidt, R; Chauhan, G; Satizabal, Cl; Becker, Jt; Yanek, L; van der Lee, Sj; Ebling, M; Fischl, B; Jr, Longstreth WT; Greve, D; Schmidt, H; Nyquist, P; Vinke, Ln; van Duijn, Cm; Xue, L; Mazoyer, B; Bis, Jc; Gudnason, V; Seshadri, S; Arfan Ikram, M; Martin, Ng; Wright, Mj; Schumann, G; Franke, B; Thompson, Pm; Medlse,. NATURE. 2015; 520 (7546) 224-229

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70. Application of a MRI based index to longitudinal atrophy change in Alzheimer disease, mild cognitive impairment and healthy older individuals in the AddNeuroMed cohort. Carlos Aguilar; J-Sebastian Muehlboeck; Patrizia Mecocci; Bruno Vellas; Magda Tsolaki; Iwona Kloszewska; Hilkka Soininen; Simon Lovestone; Lars-Olof Wahlund; Andrew Simmons and Eric Westman; for the AddNeuroMed Consortium. FRONTIERS IN AGING NEUROSCIENCE. 2014; 6 (145) -

71. Approaching Neurological Diseases to Reduce Mobility Limitations in Older Persons. Lauretani F; Ceda GP; Pelliccioni P; Ruffini L; Nardelli A; Cherubini A; Maggio M. CURRENT PHARMACEUTICAL DESIGN. 2014; 20. () 3149-3164

72. Body composition markers in older persons with COPD. Abbatecola AM; Fumagalli A; Spazzafumo L; Betti V; Misuraca C; Corsonello A; Cherubini A; Guffanti EE; Lattanzio F. AGE AND AGEING. 2014; 2014 Jul;43(4):548-53 () 548-553

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74. Candidate blood proteome markers of Alzheimer's disease onset and progression: a systematic review and replication study. Kiddle SJ; Sattlecker M; Proitsi P; Simmons A; Westman E; Bazenet C; Nelson SK; Williams S; Hodges A; Johnston C; Soininen H; Kłoszewska

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75. CERAD neuropsychological compound scores are accurate in detecting prodromal Alzheimer's disease: a prospective AddNeuroMed study. Paajanen T; Hänninen T; Tunnard C; Hallikainen M; Mecocci P; Sobow T; Tsolaki M; Vellas B; Lovestone S; Soininen H. JOURNAL OF ALZHEIMER'S DISEASE. 2014; 39 () 679-690

76. Clinical trials and late-stage drug development for Alzheimer's disease: an appraisal from 1984 to 2014. Schneider LS; Mangialasche F; Andreasen N; Feldman H; Giacobini E; Jones R; Mantua V; Mecocci P; Pani L; Winblad B; Kivipelto M. JOURNAL OF INTERNAL MEDICINE. 2014; 275 () 251-283

77. Evidence of altered phosphatidylcholine metabolism in Alzheimer's disease. Whiley L; Sen A; Heaton J; Proitsi P; García-Gómez D; Leung R; Smith N; Thambisetty M; Kloszewska I; Mecocci P; Soininen H; Tsolaki M; Vellas B; Lovestone S; Legido-Quigley C; AddNeuroMed Consortium. NEUROBIOLOGY OF AGING. 2014; 35 () 271-278

78. Genetic predisposition to increased blood cholesterol and triglyceride lipid levels and risk of Alzheimer disease: a Mendelian randomization analysis. Proitsi, P; Lupton, Mk; Velayudhan, L; Newhouse, S; Fogh, I; Tsolaki, M; Daniilidou, M; Pritchard, M; Kloszewska, I; Soininen, H; Mecocci, P; Vellas, B; Williams, J; Stewart, R; Sham, P; Lovestone, S; Powell, Jf. PLOS ONE. 2014; 11 () e1001713-

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81. Influence of +1245 A/G MT1A polymorphism on advanced glycation end products (AGEs) in elderly: effect of zinc supplementation. Robertina Giacconi; Andreas Simm; Alexander Navarrete Santos; Laura Costarelli; Marco Malavolta; Patrizia Mecocci; Francesco Piacenza; Andrea Basso; Tamas Fulop; Lothar Rink; George Dedoussis; Stavroula Kanoni; Georges Herbein; Jolanta Jajte; Eugenio Mocchegiani. GENES AND NUTRITION. 2014; 9 (5) 426-

82. Influence of age, disease onset and ApoE4 on visual medial temporal lobe atrophy cut-offs. Pereira JB;Cavallin L;Spulber G;Aguilar C; Mecocci P; Vellas B; Tsolaki M; Kłoszewska I; Soininen H; Spenger C; Aarsland D; Lovestone S; Simmons A; Wahlund LO; Westman E; AddNeuroMed consortium and for the Alzheimer's Disease Neuroimaging Initiative. JOURNAL OF INTERNAL MEDICINE. 2014; 275 () 317-330

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86. Per la creazione di linee guida sulla valutazione cognitiva dell’anziano. Martina Pigliautile; Patrizia Mecocci; Stefano Federici; Marta Olivetti Belardinelli. PSICOGERIATRIA. 2014; 9 (3) 14-25

87. Physical performance measures and polypharmacy among hospitalized older adults: Results from the crime study. F. Sganga; D. L. Vetrano; S. Volpato; A. Cherubini; C. Ruggiero; A. Corsonello; P. Fabbietti; F. Lattanzio; R. Bernabei; G. Onder. THE JOURNAL OF NUTRITION, HEALTH & AGING. 2014; 6 () 616-621

88. Plasma antioxidants and brain glucose metabolism in elderly subjects with cognitive complaints. Picco A; Polidori MC; Ferrara M; Cecchetti R; Arnaldi D; Baglioni M; Morbelli S; Bastiani P; Bossert I; Fiorucci G; Brugnolo A; Dottorini ME; Nobili F; Mecocci P. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2014; 41 () 764-775

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91. Predicting progression of Alzheimer's disease using ordinal regression. Doyle OM; Westman E; Marquand AF; Mecocci P; Vellas B; Tsolaki M; Kłoszewska I; Soininen H; Lovestone S; Williams SC; Simmons A. PLOS ONE. 2014; 9 (8) e105542-

92. Predictors of length of hospital stay among older adults admitted to acute care wards: a multicentre observational study. Vetrano DL; Landi F; De Buyser SL; Carfì A; Zuccalà G; Petrovic M; Volpato S; Cherubini A; Corsonello A; Bernabei R; Onder G. EUROPEAN JOURNAL OF INTERNAL MEDICINE. 2014; 25 () 56-62

93. Prescription drug use among older adults in Italy: A countrywide perspective. Onder, G; Vetrano, Dl; Cherubini, A; Fini, M; Mannucci, Pm; Marengoni, A; Monaco, A; Nobili, A; Pecorelli, S; Russo, P; Vitale, C; Bernabei, R. JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2014; 15 () 531.e11-531.e15

94. Prevalence and clinical correlates of sarcopenia in community-dwelling older people: application of the EWGSOP definition and diagnostic algorithm. Volpato S; Bianchi L; Cherubini A; Landi F; Maggio M; Savino E; Bandinelli S; Ceda GP; Guralnik JM; Zuliani G; Ferrucci L. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2014; 69 () 438-446

95. Random Forest ensembles for detection and prediction of Alzheimer's disease with a good between-cohort robustness. Lebedev AV, Westman E, Van Westen GJ, Kramberger MG, Lundervold A, Aarsland D, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Simmons A; Alzheimer's Disease Neuroimaging Initiative and the AddNeuroMed consortium.. NEUROIMAGE. 2014; 6 () 115-125

96. Relationship between vitamin D and inflammatory markers in older individuals. De Vita, F; Lauretani, F; Bauer, J; Bautmans, I; Shardell, M; Cherubini, A; Bondi, G; Zuliani, G; Bandinelli, S; Pedrazzoni, M; Dall'Aglio, E; Ceda, Gp; Maggio, M. AGE. 2014; 36 (4) -

97. Resveratrol Levels and All-Cause Mortality in Older Community-Dwelling Adults. Semba RD; Ferrucci L; Bartali B; Urpí-Sarda M; Zamora-Ros R; Sun K; Cherubini A; Bandinelli S; Andres-Lacueva C. JAMA INTERNAL MEDICINE. 2014; 174 () 1077-1084

98. The PREDICT (increasing the participation of the elderly in clinical trials) study: The charter and beyond. Crome, P; Cherubini, A; Oristrell, J. EXPERT REVIEW OF CLINICAL PHARMACOLOGY. 2014; 7 () 457-468

99. A Blood Gene Expression Marker of Early Alzheimer's disease. Lunnon K; Sattlecker M; Furney SJ; Coppola G; Simmons A; Proitsi P; Lupton MK; Lourdusamy A; Johnston C; Soininen H; Kłoszewska I; Mecocci P; Tsolaki M; Vellas B; Geschwind D; Lovestone S; Dobson R; Hodges A;. JOURNAL OF ALZHEIMER'S DISEASE. 2013; 33 () 737-753

100. An MRI-based index to measure the severity of Alzheimer’s disease-like structural pattern in subjects with mild cognitive impairment. Spulber G; Simmons A; Muehlboeck JS; Mecocci P; Vellas B; Tsolaki M; Kłoszewska I; Soininen H; Spenger C; Lovestone S; Wahlund LO; Westman E;. JOURNAL OF INTERNAL MEDICINE. 2013; 273 () 396-409

101. Are ongoing trials on hematologic malignancies still excluding older subjects? Antonio Cherubini; Francesca Pierri; Beatrice Gasperini; Elisa Zengarini; Annarita Cerenzia; Elisabetta Bonifacio; Flavio Falcinelli; and Fabrizia Lattanzio. HAEMATOLOGICA. 2013; 98 (7) 997-1000

102. Body mass index, lifestyles, physical performance and cognitive decline: the "Treviso Longeva (TRELONG)" study. Gallucci M; Mazzuco S; Ongaro F; Di Giorgi E; Mecocci P; Cesari M; Albani D; Forloni GL; Durante E; Gajo GB; Zanardo A; Siculi M; Caberlotto L; Regini C. THE JOURNAL OF NUTRITION, HEALTH & AGING. 2013; 17 () 378-384

103. CERAD Neuropsychological Total Scores Reflect Cortical Thinning in Prodromal Alzheimer's disease. Paajanen T; Hänninen T; Aitken A; Hallikainen M; Westman E; Wahlund LO; Sobow T; Mecocci P; Tsolaki M; Vellas B; Muehlboeck S; Spenger C; Lovestone S; Simmons A; Soininen H; AddNeuroMed Consortium. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS. EXTRA. 2013; 3 () 446-458

104. Classification and prediction of clinical diagnosis of Alzheimer's disease based on MRI and plasma measures of α-/γ-tocotrienols and γ-tocopherol. Mangialasche F; Westman E; Kivipelto M; Muehlboeck JS; Cecchetti R; Baglioni M; Tarducci R; Gobbi G; Floridi P; Soininen H; Kłoszewska I; Tsolaki M; Vellas B; Spenger C; Lovestone S; Wahlund LO; Simmons A; Mecocci P. JOURNAL OF INTERNAL MEDICINE. 2013; 273 () 602-621

105. Determinants and clinical significance of plasma oxidized LDLs in older individuals. A 9 years follow-up study. Zuliani G; Morieri ML; Volpato S; Vigna GB; Tch CB; Maggio M; Cherubini A; Bandinelli S; Guralnik JM; Ferrucci L. ATHEROSCLEROSIS. 2013; 226 () 201-207

106. Different multivariate techniques for automated classification of MRI data in Alzheimer's disease and mild cognitive impairment. Aguilar C; Westman E; Muehlboeck JS; Mecocci P; Vellas B; Tsolaki M; Kloszewska I; Soininen H; Lovestone S; Spenger C; Simmons A; Wahlund LO. PSYCHIATRY RESEARCH. 2013; 212 () 89-98

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108. High concentrations of a urinary biomarker of polyphenol intake are associated with decreased mortality in older adults. Zamora-Ros R; Rabassa M; Cherubini A; Urpí-Sardà M; Bandinelli S; Ferrucci L; Andres-Lacueva C. JOURNAL OF NUTRITION. 2013; 143 () 1445-1450

109. Identification of functional variants from whole-exome sequencing, combined with neuroimaging genetics. Nho, K; Corneveaux, Jj; Kim, S; Lin, H; Risacher, Sl; Shen, L; Swaminathan, S; Ramanan, Vk; Liu, Y; Foroud, T; Inlow, Mh; Siniard, Al; Reiman, Ra; Aisen, Ps; Petersen, Rc; Green, Rc; Jack, Cr; Weiner, Mw; Baldwin, Ct; Lunetta, K; Farrer, La; Furney, Sj; Lovestone, S; Simmons, A; Mecocci, P; Vellas, B; Tsolaki, M; Kloszewska, I; Soininen, H; Mcdonald, Bc; Farlow, Mr; Ghetti, B; Huentelman, Mj; Saykin, Aj. MOLECULAR PSYCHIATRY. 2013; 18 () 739-

110. Inflammatory proteins in plasma are associated with severity of Alzheimer's disease. Leung R; Proitsi P; Simmons A; Lunnon K; Güntert A; Kronenberg D; Pritchard M; Tsolaki M; Mecocci P; Kloszewska I; Vellas B; Soininen H; Wahlund LO; Lovestone S.. PLOS ONE. 2013; 8 (6) e64971-

111. Lymphocyte mitochondria: toward identification of peripheral biomarkers in the progression of Alzheimer disease. Sultana R; Baglioni M; Cecchetti R; Cai J; Klein JB; Bastiani P; Ruggiero C; Mecocci P; Allan Butterfield D. FREE RADICAL BIOLOGY & MEDICINE. 2013; 65 () 595-606

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113. Pattern of medication use among older inpatients in seven hospitals in Italy: results from the CRiteria to assess Appropriate Medication use among Elderly complex patients (CRIME) project. Tosato M; Settanni S; Antocicco M; Battaglia M; Corsonello A; Ruggiero C; Volpato S; Fabbietti P; Lattanzio F; Bernabei R; Onder G. CURRENT DRUG SAFETY. 2013; 8 () 98-103

114. Pattern of use and presenting complaints of older patients visiting an Emergency Department in Italy. Salvi F; Mattioli A; Giannini E; Vita D; Morichi V; Fallani M; Dessì-Fulgheri P; Cherubini A. AGING CLINICAL AND EXPERIMENTAL RESEARCH. 2013; 25 () 583-590

115. Predictive validity of different modified versions of the Identification of Seniors at Risk. Salvi F; Belluigi A; Cherubini A. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2013; 61 () 462-464

116. Prevalence and potentially reversible factors associated with anorexia among older nursing home residents: results from the ULISSE project. Landi F; Lattanzio F; Dell'Aquila G; Eusebi P; Gasperini B; Liperoti R; Belluigi A; Bernabei R; Cherubini A. JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2013; 14 () 119-124

117. Promoting access to innovation for frail old persons. IAGG (International Association of Gerontology and Geriatrics), WHO (World Health Organization) and SFGG (Société Française de Gériatrie et de Gérontologie) Workshop--Athens January 20-21, 2012. Berrut G; Andrieu S; Araujo de Carvalho I; Baeyens JP; Bergman H; Cassim B; Cerreta F; Cesari M; Cha HB; Chen LK; Cherubini A; Chou MY; Cruz-Jentoft AJ;De Decker L;Du P;Forette B;Forette F;Franco A;Guimaraes R;Guttierrez-Robledo LM;Jauregui J;Khavinson V;Lee WJ;Peng LN;Perret-Guillaume C;Petrovic M;Retornaz F;Rockwood K;Rodriguez-Manas L;Sieber C;Spatharakis G;Theou O;Topinkova E;Vellas B;Benetos A. THE JOURNAL OF NUTRITION, HEALTH & AGING. 2013; 17 () 688-693

118. Serum levels of vitamin E forms and risk of cognitive impairment in a Finnish cohort of older adults. Mangialasche F; Solomon A; Kåreholt I; Hooshmand B; Cecchetti R; Fratiglioni L; Soininen H; Laatikainen T; Mecocci P; Kivipelto M. EXPERIMENTAL GERONTOLOGY. 2013; 48 () 1428-1435

119. Subsyndromal delirium and its determinants in elderly patients hospitalized for acute medical illness. Zuliani G; Bonetti F; Magon S; Prandini S; Sioulis F; D'Amato M; Zampi E; Gasperini B; Cherubini A. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2013; 68 () 1296-1302

120. The UP-TECH project, an intervention to support caregivers of Alzheimer's disease patients in Italy: study protocol for a randomized controlled trial. Chiatti C; Masera F; Rimland JM; Cherubini A; Scarpino O; Spazzafumo L; Lattanzio F; UP-TECH research group. TRIALS. 2013; 14 () -

121. TREM2 variants in Alzheimer's disease. Guerreiro R; Wojtas A; Bras J; Carrasquillo M; Rogaeva E; Majounie E; Cruchaga C; Sassi C; Kauwe JS; Lupton MK; Ryten M; Brown K; Lowe J; Ridge PG; Hammer MB; Wakutani Y; Hazrati L; Proitsi P; Newhouse S; Lohmann E; Erginel-Unaltuna N; Medway C; Hanagasi H; Troakes C; Gurvit H; Bilgic B; Al-Sarraj S; Benitez B; Cooper B; Carrell D; Emre M; Zou F; Ma L; Murray M; Dickson D; Younkin S; Petersen RC; Corcoran CD; Cai Y; Oliveira C; Ribeiro MH; Santana I; Tschanz JT; Gibbs J; Norton MC; Kloszewska I; Mecocci P; Soininen H; Tsolaki M; Vellas B; Munger RG; Mann DM; Pickering-Brown S; Lovestone S; Beck J; Mead S; Collinge J; Parsons L; Pocock J; Morris JC; Revesz T; Lashley T; Fox NC; Rossor MN; Grenier-Boley B; Bellenguez C; Moskvina V; Sims R; Harold D; Williams J; Lambert JC; Amouyel P; Graff-Radford N; Goate A; Rademakers R; Morgan K; Powell J; St George-Hyslop P; Singleton A; Hardy J; Gerrish A; Chapman J; Abraham R; Hollingworth P; Hamshere M; Pahwa JS; Dowzell K; Williams A; Jones N; Thomas C; Stretton A; Morgan A; Williams K; Thomas S; Brayne C; Rubinsztein DC; Gill M; Lawlor

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B; Lynch A; Passmore P; Craig D; McGuinness B; Johnston JA; Todd S; Holmes C; Smith A; Love S; Kehoe PG; Maier W; Jessen F; Heun R; Kölsch H; Schürmann B; Ramirez A; van den Bussche H; Heuser I; Kornhuber J; Wiltfang J; Dichgans M; Frölich L; Hampel H; Hüll M; Rujescu D; Nowotny P; Mayo K; Livingston G; Bass NJ; Gurling H; McQuillin A; Gwilliam R; Deloukas P; Nöthen MM; Holmans P; O'Donovan M; Owen MJ; Zelenika D; Epelbaum J; Dartigues JF; Tzourio C; Berr C; Boland A; Campion D; Alpérovitch A; Lathrop M; Smith C; Trabzuni D; Walker R; Weale M. NEW ENGLAND JOURNAL OF MEDICINE. 2013; 368 () 117-127

122. Use of proton pump inhibitors is associated with lower trabecular bone density in older individuals. Maggio M; Lauretani F; Ceda GP; De Vita F; Bondi G; Corsonello A; Cattabiani C; Lattanzio F; Ruggiero C; Nouvenne A; Meschi T; Bandinelli S; Ferrucci L. BONE. 2013; 57 () 437-442

123. Whole-exome sequencing and imaging genetics identify functional variants for rate of change in hippocampal volume in mild cognitive impairment. Nho K, Corneveaux JJ, Kim S, Lin H, Risacher SL, Shen L, Swaminathan S, Ramanan VK, Liu Y, Foroud T, Inlow MH, Siniard AL, Reiman RA, Aisen PS, Petersen RC, Green RC, Jack CR, Weiner MW, Baldwin CT, Lunetta K, Farrer LA; for the Multi-Institutional Research on Alzheimer Genetic Epidemiology (MIRAGE) Study, Furney SJ, Lovestone S, Simmons A, Mecocci P, Vellas B, Tsolaki M, Kloszewska I, Soininen H; for the AddNeuroMed Consortium, McDonald BC, Farlow MR, Ghetti B; for the Indiana Memory and Aging Study, Huentelman MJ, Saykin AJ. MOLECULAR PSYCHIATRY. 2013; 18 () 781-787

124. A review of the major vascular risk factors related to Alzheimer's disease. Polidori MC; Pientka L; Mecocci P. JOURNAL OF ALZHEIMER'S DISEASE. 2012; 32 () 521-530

125. Adverse drug events as a cause of hospitalization in older adults. Salvi F; Marchetti A; D'Angelo F; Boemi M; Lattanzio F; Cherubini

A. DRUG SAFETY. 2012; 35 Suppl 1 () 29-45 126. Alzheimer's disease and age-related macular degeneration have different genetic models for complement gene variation. Proitsi P;

Lupton MK; Dudbridge F; Tsolaki M; Hamilton G; Daniilidou M; Pritchard M; Lord K; Martin BM; Craig D; Todd S; McGuinness B; Hollingworth P; Harold D; Kloszewska I; Soininen H; Mecocci P; Velas B; Gill M; Lawlor B; Rubinsztein DC; Brayne C; Passmore PA; Williams J; Lovestone S; Powell JF;. NEUROBIOLOGY OF AGING. 2012; 33 () e9-e17

127. Alzheimer's disease biomarker discovery using in silico literature mining and clinical validation. Greco I; Day N; Riddoch-Contreras J; Reed J; Soininen H; K 322 Oszewska I; Tsolaki M; Vellas B; Spenger C; Mecocci P; Wahlund LO; Simmons A; Barnes J; Lovestone SS.. JOURNAL OF TRANSLATIONAL MEDICINE. 2012; 10 () 217-

128. An ontology-based personalization of health-care knowledge to support clinical decisions for chronically ill patients. Riaño D; Real F; López-Vallverdú JA; Campana F; Ercolani S; Mecocci P; Annicchiarico R; Caltagirone C. JOURNAL OF BIOMEDICAL INFORMATICS. 2012; 45 () 429-446

129. Antioxidant clinical trials in mild cognitive impairment and Alzheimer's disease. Mecocci P.; Polidori M.C. BIOCHIMICA ET BIOPHYSICA ACTA. 2012; 1822 () 631-638

130. Decreased expression and increased oxidation of plasma haptoglobin in Alzheimer disease: Insights from redox proteomics. Cocciolo A; Di Domenico F; Coccia R; Fiorini A; Cai J; Pierce WM; Mecocci P; Butterfield DA; Perluigi M; FREE RADICAL BIOLOGY & MEDICINE. 2012; 53 () 1868-1876

131. Education increases reserve against Alzheimer's disease-evidence from structural MRI analysis. Liu Y; Julkunen V; Paajanen T; Westman E; Wahlund LO; Aitken A; Sobow T; Mecocci P; Tsolaki M; Vellas B; Muehlboeck S; Spenger C; Lovestone S; Simmons A; Soininen H;. NEURORADIOLOGY. 2012; 54 () 929-938

132. Fetal variant of circle of the Willis and bilateral symmetrical parietal stroke. Ricci M; Cornacchiola V; Pigliautile M; Ercolani S; Mecocci P. NEUROLOGICAL SCIENCES. 2012; 33 () 309-311

133. Frontotemporal atrophy associated with paranoid delusions in women with Alzheimer's disease. D. Whitehead; C. Tunnard; C. Hurt; L. O. Wahlund; P. Mecocci; M. Tsolaki; B. Vellas; C. Spenger; I. Kłoszewska; H. Soininen; D. Cromb; S. Lovestone and A. Simmons on behalf of the AddNeuroMed Consortium. INTERNATIONAL PSYCHOGERIATRICS. 2012; 24 () 99-107

134. HO-1/BVR-a system analysis in plasma from probable Alzheimer's disease and mild cognitive impairment subjects: a potential biochemical marker for the prediction of the disease. Di Domenico F; Barone E; Mancuso C; Perluigi M; Cocciolo A; Mecocci P; Butterfield DA; Coccia R; JOURNAL OF ALZHEIMER'S DISEASE. 2012; 32 () 277-289

135. How legislation on decisional capacity can negatively affect the feasibility of clinical trials in patients with dementia. Galeotti F; Vanacore N; Gainotti S; Izzicupo F; Menniti-Ippolito F; Petrini C; Chiarotti F; Chattat R; Raschetti R; AdCare Study Group (Mecocci

P). DRUGS & AGING. 2012; 29 () 607-614 136. Identification of cis-regulatory variation influencing protein abundance levels in human plasma. Lourdusamy A; Newhouse S; Lunnon

K; Proitsi P; Powell J; Hodges A; Nelson SK; Stewart A; Williams S; Kloszewska I; Mecocci P; Soininen H;Tsolaki M;Vellas B;Lovestone S;Dobson R;AddNeuroMed Consortium;Alzheimer's Disease Neuroimaging Initiative. HUMAN MOLECULAR GENETICS. 2012; 21 () 3719-3726

137. Metabolismo energetico nell’anziano. E Spagnolo; R Radicchi; Mf Croce; A Elmo; T Mariani; E Zampi; R Serra; C Ruggiero. GIORNALE DI GERONTOLOGIA. 2012; () -

138. Mitochondrial Dysfunction and Immune Activation are Detectable in Early Alzheimer's Disease Blood. Lunnon K; Ibrahim Z; Proitsi P; Lourdusamy A; Newhouse S; Sattlecker M; Furney S; Saleem M; Soininen H; Kłoszewska I; Mecocci P; Tsolaki M; Vellas B; Coppola G; Geschwind D; Simmons A; Lovestone S; Dobson R; Hodges A;. JOURNAL OF ALZHEIMER'S DISEASE. 2012; 30 () 685-710

139. Optimizing pharmacotherapy in older patients. A European perspective. O’Mahony D.; Cherubini A.; Petrovic M. DRUGS & AGING. 2012; 29 () 423-425

140. Plasma Based Markers of [(11) C] PiB-PET Brain Amyloid Burden. Kiddle SJ; Thambisetty M; Simmons A; Riddoch-Contreras J; Hye A; Westman E; Pike I; Ward M; Johnston C; Lupton MK; Lunnon K; Soininen H; Kloszewska I; Tsolaki M; Vellas B; Mecocci P; Lovestone S; Newhouse S; Dobson R. PLOS ONE. 2012; 7 (e44260) -

141. Plasma Levels of Complement 4a Protein are increased in Alzheimer's disease. Bennett S; Grant M; Creese AJ; Mangialasche F; Cecchetti R; Cooper HJ; Mecocci P; Aldred S.. ALZHEIMER DISEASE & ASSOCIATED DISORDERS. 2012; 26 () 329-334

142. Predictors of hospitalization in Italian nursing home residents: the U.L.I.S.S.E. project. Cherubini A; Eusebi P; Dell'Aquila G; Landi F; Gasperini B; Bacuccoli R; Menculini G; Bernabei R; Lattanzio F; Ruggiero C. JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2012; 13 () 84.e5-84.e10,

143. Prior antiplatelet drug use and short-term mortality in older patients with acute ischemic stroke (AIS). Zuliani G; Galvani M; Bonetti F; Prandini S; Magon S; Gasperini B; Ruggiero C; Cherubini A. ARCHIVES OF GERONTOLOGY AND GERIATRICS. 2012; 54 () 214-217

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144. Progression of Alzheimer disease in Europe: Data from the European ICTUS study. Vellas B; Hausner L.; Frölich L; Cantet C; Gardette V; Reynish E; Gillette S; Agüera-Morales E; Auriacombe S; Boada-Rovira M; Bullock R; Byrne J; Camus V; Cherubini A; Costa-Tsolaki M; Eriksdotter-Jönhagen M; Frisoni GB; Hasselbalch S; Jones RW; Martinez-Lage P; Olde Rikkert M; Ousset PJ; Pasquier F; Ribera-Casado JM; Rigaud AS; Robert P; Rodriguez G; Salmon E; Salva A; Scheltens P; Schneider A; Sinclair A; Spiru L; Touchon J; Zekry D; Winblad B; Andrieu S.. CURRENT ALZHEIMER RESEARCH. 2012; 9 () 902-912

145. Serum 25-Hydroxyvitamin D, Transitions Between Frailty States, and Mortality in Older Adults: The Invecchiare in Chianti Study. Shardell M; D'Adamo C; Alley DE; Miller RR; Hicks GE; Milaneschi Y; Semba RD; Cherubini A; Bandinelli S; Ferrucci L. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2012; 60 () 256-264

146. Studio di validazione dell’ACE-R in lingua italiana nella popolazione degli young-old e degli old-old. M. Pigliautile; M. Ricci; E. Mioshi; S. Ercolani; F. Mangialasche; R. Monastero; M. F. Croce; S. Federici; P. Mecocci. GIORNALE DI GERONTOLOGIA. 2012; 60 (3) 134-141

147. Subthreshold depression in older subjects: an unmet therapeutic need. Cherubini A; Nisticò G; Rozzini R; Liperoti R; Di Bari M; Zampi E; Ferrannini L; Aguglia E; Pani L; Bernabei R; Marchionni N; Trabucchi M. THE JOURNAL OF NUTRITION, HEALTH & AGING. 2012; 16 () 909-913

148. The views of older people and carers on participation in clinical trials: the PREDICT Study. Bartlam B.; Crome P.; Lally F.; Beswick A.D.; Cherubini A.; Clarfield M.A.; Edbrooke D.; Farré A.; Hertogh C.; Lesauskaite V.; Mills G.; Muller M.; Oristrell J.; I Prada G.; Ruggiero C.; Sinclair-Cohen J.; Szczerbińska K.; Topinkova E.; Zalewski Z. CLINICAL INVESTIGATION. 2012; 2 () 327-336

149. Tocopherols and tocotrienols plasma levels are associated with cognitive impairment. Mangialasche F, Xu W, Kivipelto M, Costanzi E, Ercolani S, Pigliautile M, Cecchetti R, Baglioni M, Simmons A, Soininen H, Tsolaki M, Kloszewska I, Vellas B, Lovestone S, Mecocci

P; AddNeuroMed Consortium. NEUROBIOLOGY OF AGING. 2012; 33 () 2282-2290 150. Underprescription of beneficial medicines in older adults. Causes, consequences and prevention. Cherubini A.; Corsonello A.; Lattanzio

F. DRUGS & AGING. 2012; 29 () 463-475 151. Underrecognition and undertreatment of dementia in Italian nursing homes. Cherubini A.; Ruggiero C.; Dell’Aquila G.; Eusebi P.;

Gasperini B.; Zengarini E.; Cerenzia A.; Zuliani G.; Guaita A.; Lattanzio F. JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2012; 13 (8) 759.e7-759.e13

152. AddNeuroMed and ADNI: similar patterns of Alzheimer's atrophy and automated MRI classification accuracy in Europe and North America. Westman E; Simmons A; Muehlboeck JS; Mecocci P; Vellas B; Tsolaki M; Kloszewska I; Soininen H; Weiner MW; Lovestone S; Spenger C; Wahlund LO; for the AddNeuroMed consortium and the Alzheimer’s Disease Neuroimaging Initiative. NEUROIMAGE. 2011; 58 () 818-828

153. Apathy and cortical atrophy in Alzheimer's disease. Tunnard C; Whitehead D; Hurt C; Wahlund L; P. Mecocci; Tsolaki M; Vellas B; Spenger C; Koszewska I; Soininen H; Lovestone S; Simmons A. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2011; (26) 741-748

154. Automated hippocampal shape analysis predicts the onset of dementia in mild cognitive impairment. Costafreda SG; Dinov ID; Tu Z; Shi Y; Liu CY; Kloszewska I; Mecocci P; Soininen H; Tsolaki M; Vellas B; Wahlund LO; Spenger C; Toga AW; Lovestone S; Simmons A. NEUROIMAGE. 2011; 56 () 212-219

155. Chronic kidney disease and 1-year survival in elderly patients discharged from acute care hospitals: a comparison of three glomerular filtration rate equations. Corsonello A; Pedone C; Lattanzio F; Cherubini A; Onder G; Corica F; Pranno L; Mari V; Laino I; Garasto S; Antonelli Incalzi R. NEPHROLOGY DIALYSIS TRANSPLANTATION. 2011; 26 () 360-364

156. Combination analysis of neuropsychological tests and structural MRI measures in differentiating AD, MCI and control groups-The AddNeuroMed study. Liu Y; Paajanen T; Zhang Y; Westman E; Wahlund Lo; Simmons A; Tunnard C; Sobow T; P. Mecocci; Tsolaki M; Vellas B; Muehlboeck S; Evans A; Spenger C; Lovestone S; Soininen H; For The Addneuromed Consortium. NEUROBIOLOGY OF AGING. 2011; 32 () 1198-1206

157. Combinatorial markers of mild cognitive impairment conversion to Alzheimer's disease-cytokines and MRI measures together predict disease progression. Furney S.J.; Kronenberg D.; Simmons A.; Güntert A.; Dobson R.J.; Proitsi P.; Wahlund L.O.; Kloszewska I.; Mecocci P.; Soininen H.; Tsolaki M.; Vellas B.; Spenger C.; Lovestone S.. JOURNAL OF ALZHEIMER'S DISEASE. 2011; 26 (suppl 3) 395-405

158. Comparison of 24-h volume and creatinine-corrected total urinary polyphenol as a biomarker of total dietary polyphenols in the InCHIANTI Study. Zamora-Ros R; Rabassa M; Cherubini A; Urpí-Sardà M; Llorach R; Bandinelli S; Ferrucci L; Andres-Lacueva C. ANALYTICA CHIMICA ACTA. 2011; 704 () 110-115

159. Deep sequencing of the Nicastrin gene in pooled DNA, the identification of genetic variants that affect risk of Alzheimer's disease. Lupton MK; Proitsi P; Danillidou M; Tsolaki M; Hamilton G; Wroe R; Pritchard M; Lord K; Martin BM; Kloszewska I; Soininen H; Mecocci P; Vellas B; Harold D; Hollingworth P; Lovestone S; Powell JF. PLOS ONE. 2011; 6 () e17298-

160. Effectiveness of a high-throughput genetic analysis in the identification of responders/non-responders to CYP2D6-metabolized drugs. Savino M; Seripa D; Gallo AP; Garrubba M; D'Onofrio G; Bizzarro A; Paroni G; Paris F; Mecocci P; Masullo C; Pilotto A; Santini SA. CLINICAL LABORATORY. 2011; 57 () 887-893

161. Exclusion of older people from clinical trials: professional views from nine European countries participating in the Predict study. Crome P; Lally F; Cherubini A; Oristrell J; Beswick AD; Clarfield AM; Hertogh C; Lesauskaite V; Prada GI; Szczerbińska K; Topinkova E; Sinclair-Cohen J; Edbrooke D; Mills G. DRUGS & AGING. 2011; 28 () 667-677

162. Genetic Loci Associated with Plasma Phospholipid n-3 Fatty Acids: A Meta-Analysis of Genome-wide Association Studies from the CHARGE Consortium. Lemaitre R.; Tanaka T.; Weihong T.; Manichaikul A.; Foy M.; Kabagambe K.E.; Nettleton J.A.; King I.B.; Weng L.C; Bhattacharya S.; Bandinelli S.; Bis J.C.; Rich S.S.; Jacobs D.R. Jr.; Cherubini A.; McKnight B.; Liang S.; Gu X.; Rice K.; Laurie C.C.; Lumley T.; Browning B.L.; Psaty B.M.; Chen Y.I.; Friedlander Y.; Djousse L.; Wu J.H.Y.; Siscovick D.S.; Uitterlinden A.G.; Arnett D.K.; Ferrucci L.; Fornage M.; Tsai M.Y.; Mozaffarian D.; Steffen L.M.. PLOS GENETICS. 2011; 7 (e1002193) -

163. Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease. Furney SJ; Simmons A; Breen G; Pedroso I; Lunnon K; Proitsi P; Hodges A; Powell J; Wahlund LO; Kloszewska I; Mecocci P; Soininen H; Tsolaki M; Vellas B; Spenger C; Lathrop M; Shen L; Kim S; Saykin AJ; Weiner MW; Lovestone S.. MOLECULAR PSYCHIATRY. 2011; 16 () 1130-1138

164. Hyperparathyroidism in the elderly: shifting the focus from bone to brain. Maggio D.; Ruggiero C. AGING CLINICAL AND EXPERIMENTAL RESEARCH. 2011; 23 () 326-327

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165. Increased protein and lipid oxidative damage in mitochondria isolated from lymphocytes from patients with Alzheimer's disease: insights into the role of oxidative stress in Alzheimer's disease and initial investigations into a potential biomarker for this dementing disorder. Sultana R; Mecocci P; Mangialasche F; Cecchetti R; Baglioni M; Butterfield DA. JOURNAL OF ALZHEIMER'S DISEASE. 2011; 24 () 77-84

166. L’assistenza sanitaria alla popolazione anziana in Italia: il progetto ULISSE (Un Link Informatico sui Servizi Sanitari Esistenti per l’anziano). F Lattanzio; C Mussi; E Scafato; C Ruggiero; G Dell’aquila; Mg Cupido; C Pedone; F Mammarella; L Galluzzo; G Salvioli; U Senin; Pu Carbonin; R Bernabei; A Cherubini E Il Gruppo Di Studio Ulisse. GIORNALE DI GERONTOLOGIA. 2011; () -

167. Lysosomal beta-Galactosidase and beta-Hexosaminidase Activities Correlate with Clinical Stages of Dementia Associated with Alzheimer's disease and Type 2 Diabetes Mellitus. Tiribuzi R.; Orlacchio A.; Crispoltoni L.; Maiotti M.; Zampolini M.; De Angelis M.; Mecocci P.; Cecchetti R.; Bernardi G.; Datti A.; Martino S.; Orlacchio A. JOURNAL OF ALZHEIMER'S DISEASE. 2011; 24 (4) 785-797

168. Medical licensing for older people. R. Martin; A. Cherubini; D. O’Neill. EUROPEAN GERIATRIC MEDICINE. 2011; 2 () 319-321 169. Multivariate analysis of MRI data for Alzheimer's disease, mild cognitive impairment and healthy controls. WESTMAN E; SIMMONS

A; ZHANG Y; MUEHLBOECK JS; TUNNARD C; LIU Y; COLLINS L; EVANS A; P. MECOCCI; VELLAS B; TSOLAKI M; K; OSZEWSKA I; SOININEN H; LOVESTONE S; SPENGER C; WAHLUND LO. NEUROIMAGE. 2011; 54 () 1178-1187

170. Neuropsychiatric symptoms, endophenotypes, and syndromes in late-onset Alzheimer's disease: focus on APOE gene. Panza F; Seripa D; D'Onofrio G; Frisardi V; Solfrizzi V; Mecocci P; Pilotto A. JOURNAL OF ALZHEIMER'S DISEASE. 2011; (doi: 10.4061/2011/72145) -

171. Plasma Biomarkers of Brain Atrophy in Alzheimer's disease. Thambisetty M, Simmons A, Hye A, Campbell J, Westman E, Zhang Y, Wahlund LO, Kinsey A, Causevic M, Killick R, Kloszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, Spenger C, Lovestone S; for the AddNeuroMed consortium.. PLOS ONE. 2011; 6: e28527 () -

172. Prevalence of potentially inappropriate prescribing in an acutely ill population of older patients admitted to six European hospitals. Gallagher P; Lang PO; Cherubini A; Topinková E; Cruz-Jentoft A; Montero Errasquín B; Mádlová P; Gasperini B; Baeyens H; Baeyens JP; Michel JP; O'Mahony D.. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2011; 67 () 1175-1188

173. Role of cytochrome P4502D6 functional polymorphisms in the efficacy of donepezil in patients with Alzheimer's disease. Seripa D; Bizzarro A; Pilotto A; D Onofrio G; Vecchione G; Gallo Ap; Cascavilla L; Paris F; Grandone E; P. Mecocci; Santini Sa; Masullo C; Pilotto A. PHARMACOGENETICS AND GENOMICS. 2011; (21) 225-230

174. Sensitivity and specificity of medial temporal lobe visual ratings and multivariate regional MRI classification in Alzheimer's disease. Westman E, Cavallin L, Muehlboeck JS, Zhang Y, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Soininen H, Spenger C, Lovestone S, Simmons A, Wahlund LO; AddNeuroMed consortium. PLOS ONE. 2011; (6: e22506) -

175. The AddNeuroMed framework for multi-centre MRI assessment of Alzheimer's disease: experience from the first 24 months. Simmons A, Westman E, Muehlboeck S, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Wahlund LO, Soininen H, Lovestone S, Evans A, Spenger C; for the AddNeuroMed consortium.. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2011; 26 () 75-82

176. The effect of polyunsaturated fatty acids on bone health. Maggio M.; Artoni A.; Lauretani F.; Ruggiero C.; Cederholm T.; Cherubini A.; Ceda G.P. REVIEWS IN CLINICAL GERONTOLOGY. 2011; 21 () 219-232

177. The persistent exclusion of older patients from ongoing clinical trials regarding heart failure. Cherubini A; Oristrell J; Pla X; Ruggiero

C; Ferretti R; Diestre G; Clarfield AM; Crome P; Hertogh C; Lesauskaite V; Prada GI; Szczerbinska K; Topinkova E; Sinclair-Cohen J; Edbrooke D; Mills GH. ARCHIVES OF INTERNAL MEDICINE. 2011; 171 () 550-556

178. The prevention of adverse drug reactions in older subjects. Cherubini A; Ruggiero C; Gasperini B; Dell'Aquila G; Cupido MG; Zampi E; Zengarini E; Nguyen NH; Serra R; Corsonello A; Lattanzio F. CURRENT DRUG METABOLISM. 2011; 12 () 652-657

179. Towards a tailored assessment and care for older onco-haematological patients. S. Camporesi; J.G. McVie; A. Cherubini. EUROPEAN GERIATRIC MEDICINE. 2011; 2 () 319-321

180. Validation study of the Italian Addenbrooke’s Cognitive Examination Revised in a young-old and old-old population. Pigliautile, M; Ricci, M; Mioshi, E; Ercolani, S; Mangialasche, F; Monastero, R; Croce, Mf; Federici, S; Mecocci, P. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS. 2011; 32 (5) 301-307