(Vasopressin)aka: Antidiuretic Hormone

aka: Arginine Vasopressin

Vasopressin

• Amino acid sequence for Vasopressin is Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly

• The single most important effect of Vasopressin is to conserve body water by reducing the loss of water in urine.

• Since it is a anitdiuretic it counter acts diuretics (responsible for water loss in the human system)

Vasopressin and kidneys• Vasopressin stimulates water

reabsorbtion by stimulating "water channels" (aquaporins) into the membranes of kidney tubules.

• Aquaporins have many different functions but are in parts of the body to regulate fluid

Diabetes• The most common disease due to a lack of

vasopressin is diabetes insipidus• Without vasopressin the amount

of urinations made daily increases to such amounts as 4.2 gallons of urine a day.

• The increase of urination is due to the decrease of the amount of water that can be held in the kidneys.

sources

• http://www.vivo.colostate.edu/hbooks/pathphys/endocrine/hypopit/adh.html

• http://www.3dchem.com/molecules.asp?ID=356 website contains 3D vasopressin model