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Page 1: Explanation of autosomal recessive inheritance

Genetics and genomics for healthcarewww.geneticseducation.nhs.uk© 2013 NHS National Genetics and Genomics Education

Centre

Passing on genetic information from parents

to childrenAn explanation of autosomal

recessive inheritance

Page 2: Explanation of autosomal recessive inheritance

Genetics and genomics for healthcarewww.geneticseducation.nhs.uk© 2013 NHS National Genetics and Genomics Education

Centre

• Here are some PowerPoint teaching slides which demonstrate the transmission of an autosomal recessive condition from parent to child, please feel free to use these within your teaching

• Some parts of the animations run automatically; others require a mouse click

• Most slides have notes with further information

Page 3: Explanation of autosomal recessive inheritance

Genetics and genomics for healthcarewww.geneticseducation.nhs.uk© 2013 NHS National Genetics and Genomics Education

Centre

Hundreds of genes are located on each chromosome (The dark bands on the chromosomes are due to a special staining technique and are not genes as these are too small to see)

The 46 human chromosomes seen down the microscope

Page 4: Explanation of autosomal recessive inheritance

Genetics and genomics for healthcarewww.geneticseducation.nhs.uk© 2013 NHS National Genetics and Genomics Education

Centre

The 46 human chromosomes arranged in their 23 pairs (these are the chromosomes of a normal male)

Page 5: Explanation of autosomal recessive inheritance

Genetics and genomics for healthcarewww.geneticseducation.nhs.uk© 2013 NHS National Genetics and Genomics Education

Centre

Position of particular gene

Chromosomepair

Page 6: Explanation of autosomal recessive inheritance

Genetics and genomics for healthcarewww.geneticseducation.nhs.uk© 2013 NHS National Genetics and Genomics Education

Centre

Has the condition

Unaffected carrier for the

condition

Altered gene Altered gene

Altered geneUsual gene

Page 7: Explanation of autosomal recessive inheritance

Parents

Sperm or eggs

Autosomal recessive inheritance where both parents are carriers

Carrier for the

conditionCarrier for

the condition

Page 8: Explanation of autosomal recessive inheritance

Parents

Sperm or eggs

At conception

Autosomal recessive inheritance where both parents are carriers

Carrier for the

conditionCarrier for

the condition

Page 9: Explanation of autosomal recessive inheritance

Parents

Sperm or eggs

At conception

Autosomal recessive inheritance where both parents are carriers

Carrier for the

conditionCarrier for

the condition

Does not have the condition, non-

carrierCarrier for

the condition

Has the condition

Carrier for the

condition

Page 10: Explanation of autosomal recessive inheritance

Genetics and genomics for healthcarewww.geneticseducation.nhs.uk© 2013 NHS National Genetics and Genomics Education

Centre

This animation is part of a series describing modes of inheritance

To access these and other resources for teaching and

learning genetics, please visit:

www.geneticseducation.nhs.uk


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