School of Electrical, Electronic and Mechanical Engineering

Nano-particles and nano-structured surfaces in biomedical engineering.Dr. Kenneth Stanton

SEEME: Biomedical engineering

• Development and/or design of materials, devices and manufacturing routes for implantable biomedical components including:– Orthopaedic joints– Stents– Dentistry– Etc

• Study of mechanical properties of biomaterials and biomedical devices.

• Biomechanics of bone, joints, soft-tissue etc.

• Bio-tribology and wear.

Nano-particles evolved during wear of orthopaedic joints

• With each step there are 5x105 particles released

• Particles are found disseminated to organs around the body

• There is little understanding about the long-term biological effects of nanoparticles of the relevant materials– Effects of morphology– Fresh surfaces– Metal nanoparticle stability

Synthesis of nano-crystalline bioceramics and glass-ceramics

• HA, -TCP:– Bi-phasic calcium phosphates

• Controlled resorbability in-vivo

– Preparation of nano-structured surfaces from bioceramics using EPD from wet-precipitation.

• Apatitic glass-ceramics

Preparation of nano-structured metal-oxide surfaces using RF-magnetron sputteringEffect of deposition pressure on microstructure of TiOx coating

4 x 10-3 mbar

1 x 10-3 mbar

Courtesy of Denis Dowling