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Page 1: Technology Transfer from the University of Oxford An Introduction to Isis, Technology Transfer, and Technology Transfer Consulting WIPO 11 th September

Technology Transfer from the University of Oxford

An Introduction to Isis, Technology Transfer, and

Technology Transfer Consulting

WIPO 11th September 2008 Cardiff

Dr Roger Welch

Page 2: Technology Transfer from the University of Oxford An Introduction to Isis, Technology Transfer, and Technology Transfer Consulting WIPO 11 th September

Isis Innovation

> A company owned by the University of Oxford> To help researchers commercialise the results of their

research

Activities Patenting 50 p.a.

Licensing of intellectual property 30 p.a.

Consulting and service contracts 50 p.a.

Formation of new companies 8 p.a.

Page 3: Technology Transfer from the University of Oxford An Introduction to Isis, Technology Transfer, and Technology Transfer Consulting WIPO 11 th September

Isis Innovation Ltd

Oxford Technology TransferIP, Patents, Licences, Spin-outs, Material Sales, Seed Funds, Isis Angels Network

Oxford ExpertiseConsulting, Services

Isis Consulting Business Technology Transfer and Innovation Management

A company 100% owned by the University of Oxford

Page 4: Technology Transfer from the University of Oxford An Introduction to Isis, Technology Transfer, and Technology Transfer Consulting WIPO 11 th September

Isis Innovation Staff

Oxford University Consulting (6)Head of Group

Steve LeeProject Managers Dr Caroline Jenkins

Andrew GoffGurinder Punn

Gill RoweAdministratorKerry Antcliffe

Project Manager Teams

Dr Mairi Gibbs

Dr David Churchman Dr Emma Sceats

Dr Stuart Wilkinson

Dr Colin Story

Dr David PhillipsDr Weng Sie Wong

Dr Dina ChenYa-hsin Shen

Patent & Licence Administration

ManagerSteven Bayliss

Post-Deal AdminRidi Faruque

Patent Administrator

tba

Technology Transfer Group (25)

Head of GroupLinda Naylor

Project Manager Teams

Dr David Eastham

Dr Jamie Ferguson Dr Rakesh Roshan

Dr Mike Gilbert

Dr Adam Stoten

Dr Fiona BeggDr Sarah Deakin

Dr Christine WhyteDr John Wilson

Dr Cynthia GreenDr Erica Conway

IAN & Seed Fund Co-ordinatorAndrea Alunni

Isis Enterprise (10)Head of Group

Dr David BaghurstGeneral ManagerDr Mark MawhinneyProject Managers

Dr Sarah MacnaughtonTerry Pollard

Robert SwerdlowDr Roger WelchDr Paul WhyteDr Suzy WoodDr Tim Hart

AdministratorOlivia Thomas

Staff: 56 PhD’s: 28 MBA’s: 12

Managing DirectorTom Hockaday

Business Support (7)Head of Group

Matt SimonsAccounts

Gemma AllnuttMarketing

Renate Krelle Cynthia Warmington

LegalEmma WheatleySarah Litchfield

Central Admin (5)Office Manager

Jenny BaileyOffice Administrator

Nelson SaHR Assistant

Alex AllanFacilitiesJane TarryReceptionGillian Hicks

OSEM (2)Dr Chris TowlerJames Mallinson

Page 5: Technology Transfer from the University of Oxford An Introduction to Isis, Technology Transfer, and Technology Transfer Consulting WIPO 11 th September

Year Ending March

2000 2001 2002 2003 2004 2005 2006 2007 2008

University Investment

£1m £1m £1m £1m £1m £1.2m £1.2m £1.2m £1.2m

Staff 17 21 23 34 36 36 36 37 44

Open Projects 319 415 476 629 725 764 784 841 978

Patents filed 55 63 82 65 52 55 57 49 68

Licence Deals 21 36 42 37 31 38 45 50 74

Consultancy 34 50 48 59 89 102

Spin-outs 6 8 8 7 3 4 6 7 4

Isis Innovation 2000 - 2008

Page 6: Technology Transfer from the University of Oxford An Introduction to Isis, Technology Transfer, and Technology Transfer Consulting WIPO 11 th September

Who profits from Technology Transfer ?

> Researchers> Technology, royalties and company shares

> Industry > New Technology

> University> Royalties, shares

> Research Funding > from spinouts and licensees

> Economy> New industry and technology to existing ones

> Investors> High returns on world class science

Page 7: Technology Transfer from the University of Oxford An Introduction to Isis, Technology Transfer, and Technology Transfer Consulting WIPO 11 th September

Oxford Model - Key Ingredients

> Rich portfolio of wholly-owned IPR> Strong, world-class research base

> Diverse research sponsorship (700)

> Clear intellectual property (IP) policy > Led from the top and widely supported

> Investment in research support & tech transfer> 85 staff in Research Services and Isis Innovation

> Clear internal demarcation of responsibility

> Effective internal & external communications

Page 8: Technology Transfer from the University of Oxford An Introduction to Isis, Technology Transfer, and Technology Transfer Consulting WIPO 11 th September

Intellectual Property Policy (October 2000)

> University claims ownership of all employees’ and students’ IP

rights resulting from University research activities

> The university assists those researchers who wish to

commercialise their research

> by patenting, licences, spinout companies & consultancy

> Researchers share the benefits

> Royalty shares from licences

> Equity in spinout companies

> Income from personal consultancy

Page 9: Technology Transfer from the University of Oxford An Introduction to Isis, Technology Transfer, and Technology Transfer Consulting WIPO 11 th September

Licensing

> Licensing is when you give someone permission to use your invention in return for:

> money up front or > money when they achieve a defined event or > a share of their sales or > a share of their profits or> A combination of some or all of the above

Page 10: Technology Transfer from the University of Oxford An Introduction to Isis, Technology Transfer, and Technology Transfer Consulting WIPO 11 th September

Royalty Rates

> Tables are available but > With new technology the rate is rarely defined

> One rule of thumb:“We want a third of your incremental gross profit”

> So if they make 30% gross on sales we want 10% of sales> They do the work so they get 70%> Without our idea they don’t get anything

Page 11: Technology Transfer from the University of Oxford An Introduction to Isis, Technology Transfer, and Technology Transfer Consulting WIPO 11 th September

Licensing

Pro> They work you get paid> Can make big money> Stimulates research ideas

Con> Needs patent protection> Long time coming> Relies on licensee> May need proof of concept

(resources)> They could bury it

Page 12: Technology Transfer from the University of Oxford An Introduction to Isis, Technology Transfer, and Technology Transfer Consulting WIPO 11 th September

Spinouts

Pro> Most fun> You can make most money> You still retain some control

Con> Needs IP protection> Needs Investment> Needs management> Needs a lot of your time> Needs a lot of external advice

> Management> Lawyers> Etc.

Page 13: Technology Transfer from the University of Oxford An Introduction to Isis, Technology Transfer, and Technology Transfer Consulting WIPO 11 th September

Investors

> Investors want their money back

> They want more than they put in

> They want to know by when

> They want to know how certain

Page 14: Technology Transfer from the University of Oxford An Introduction to Isis, Technology Transfer, and Technology Transfer Consulting WIPO 11 th September

Investment SourcesInvestment Sources

Oxford University Challenge Seed Fund £4m> Launched in 1999 University £1m Treasury, Wellcome, Gatsby £3m> Development projects, spin-out seed equity; in a total of 83 projects> £4m investment has resulted in Equity stakes in 22 spin-outs, 7

completed licensing deals & 33 active technology projects> These 22 spin-outs have attracted £40m seed/venture investment

Isis Angels Network > Business Angels> Seed / Venture Capital> Private Equity> 100 Members> Events> No Charges

Page 15: Technology Transfer from the University of Oxford An Introduction to Isis, Technology Transfer, and Technology Transfer Consulting WIPO 11 th September

Oxford Spin-outs (pre 2000)

1959 Oxford Instruments *

1977 Oxford Lasers

1988 Oxford Glycosciences *

1989 Oxford Molecular *

1992 Oxford Asymmetry *

1994 PowderJect *

1995 Oxford Gene Technology

1996 Oxford Biomedica *

1997 Oxagen

1998 5 Opsys, Synaptica, Prolysis, Celoxica * , Sense Therapeutic

1999 6 Medigene(Avidex) * , Oxxon Pharmaccines, Dash, Oxonica * , AuC Sensing, OMIA

* stock exchange listing

Page 16: Technology Transfer from the University of Oxford An Introduction to Isis, Technology Transfer, and Technology Transfer Consulting WIPO 11 th September

Oxford Spin-outs (post 2000)

Total external investment to date in spin-outs Post 1997: £334m £34m Seed/Business Angels &£300m Venture/Institution Capital * stock exchange listing

2000 7Third Phase, Mindweavers, Oxford BioSignals, Oxford BioSensors, TolerRx, OXIVA, Pharma DM

2001 7OxLoc, Oxford Bee Co, Oxford Ancestors, Novarc, Oxford ArchDigital, Natural Motion, Inhibox

2002 9Pharminox, Minervation, Spinox, Zyentia, Oxitec, Oxford Immunotec, ORRA, GlycoForm, BioAnalab

2003 4 VASTOx * , ReOx, Riotech, OCSI

2004 4 Avacta(OMD) * , G-Nostics, Surface Therapeutics, EKB Technology

2005 5Oxford Nanolabs, Oxford RF Sensors, Oxbridge Pulsars, Celleron, Oxford Catalysts *

2006 7TDeltaS, Oxford Medistress, Particle Therapeutic, Aurox, Oxford Advanced Surfaces * , Cytox, OxTox

2007 4 Eykona Technologies, Clinox, Oxford Biodynamics, Crysalin

2008 [2] Semmle, Oxford-Emergent TB Consortium,

Page 17: Technology Transfer from the University of Oxford An Introduction to Isis, Technology Transfer, and Technology Transfer Consulting WIPO 11 th September

Begbroke Science & Business Park

University Department of Materials

Prolysis

Oxford Gene Technology

OxLoc

Oxonica

> Owned & operated by Oxford University> University research labs> Business Incubator & premises for new companies> Central meeting room and café

Centre for Innovation & Enterprise

Page 18: Technology Transfer from the University of Oxford An Introduction to Isis, Technology Transfer, and Technology Transfer Consulting WIPO 11 th September

> Isis Enterprise offers consulting expertise and advice in technology transfer, based upon the success of Isis Innovation as Oxford University’s technology transfer company.

> Isis Enterprise clients and services:> Governments:

policy and benchmarking studies

> Universities and research institutes: policy studies, technology audit, technology transfer office

partnerships, training and secondment programmes

> Companies: out-licensing or in-licensing support, university relationship

managementopen innovation partnerships

> Professional services firms: market validation studies

> Investors: investor readiness appraisal

> www.isis-enterprise.com

Isis Enterprise

Page 19: Technology Transfer from the University of Oxford An Introduction to Isis, Technology Transfer, and Technology Transfer Consulting WIPO 11 th September

> In December 2006, Isis became a Low Carbon Incubator in partnership with The Carbon Trust.

> Isis offers support for early stage low carbon projects to anyone in the UK involved in developing low carbon technologies with commercial potential.

> We work with: > Individuals> Companies> Universities> Research Institutes

Isis and The Carbon Trust

Page 20: Technology Transfer from the University of Oxford An Introduction to Isis, Technology Transfer, and Technology Transfer Consulting WIPO 11 th September

Sep 08

www.isis-innovation.com

Page 21: Technology Transfer from the University of Oxford An Introduction to Isis, Technology Transfer, and Technology Transfer Consulting WIPO 11 th September

Executive(policies)

Other academics

Gene pool Commercially

active scientists

The University

Tech transfer

office

Page 22: Technology Transfer from the University of Oxford An Introduction to Isis, Technology Transfer, and Technology Transfer Consulting WIPO 11 th September

StudentsBrokers

Itinerant managers Consultants

Sub-culture in a barter economy

VC’s Lawyers

Headhunters

PR agents

Realestate

LeasingBanks

Accountants

Specialist suppliers

Otherstart-ups

Page 23: Technology Transfer from the University of Oxford An Introduction to Isis, Technology Transfer, and Technology Transfer Consulting WIPO 11 th September

Contacts

Isis Innovation LtdEwert HouseEwert PlaceSummertown Oxford OX2 7SG

T 01865 280830F 01865 280831E [email protected] www.isis-innovation.com

Register to receive Isis E-News at www.isis-innovation.com/news/enews


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