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QUEENSBOROUGH COMMUNITY COLLEGE THE CITY UNIVERSITY OF NEW YORK DEPARTMENT OF BIOLOGICAL SCIENCES AND GEOLOGY GENERAL BIOLOGY I BI-201 COURSE INFORMATION Spring 2013 NAME ______________________________ SECTION ___________________________

Bio 201 course information syllabus qcc

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Page 1: Bio 201 course information syllabus qcc

QUEENSBOROUGH COMMUNITY COLLEGETHE CITY UNIVERSITY OF NEW YORK

DEPARTMENT OF BIOLOGICAL SCIENCES AND GEOLOGY

GENERAL BIOLOGY IBI-201

COURSE INFORMATIONSpring 2013

NAME ______________________________

SECTION ___________________________

John
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https://www.khanacademy.org/science/biology
John
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Use this website to help you youtube is a great tool as well
John
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Hard course, grades are not curved. BI-202 is easier and more intresting Pre for BI-202 is Bi201
John
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The book cost is about $ 200 Ask prof. if you can use an older version which u can buy online Lab book is cheap: about $ 20 from when I took the class took the class
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FACULTY

The best time to meet with faculty is during their regularly scheduledoffice hours. Messages for faculty may be left with the secretaries in

the department office: M-213 (631-6335).

Course Coordinators

Dr. P. Schneider Dr. U. Golebiewska

Office: M-208 Office: M-428

Your Lecturer: ________________________________

Office: ______________________________________

Office Hours: ________________________________

Your Lab Instructor: ____________________________

Office: _______________________________________

Office Hours: _________________________________

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TABLE OF CONTENTS

Course Prerequisites & Description …………………………………. 4

Required Books & Materials ………………………………….. 4

Policy on Cheating ……………………………………………. 5

Grading Procedures and Criteria ……………………………… 6

INC, ABS, W and WU; Early Grade Notification …………… 7

Attendance Policy ……………………………………………… 7

Study Tips ………………………………………………………. 8

Lecture Syllabus ……………………………………………….. 11

Laboratory Syllabus …………………………………………… 12

Course Objectives ……………………………………………… 13

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Course Prerequisites:

BE-112 (or 205) and BE-122 (or 226). Corequisite: BE-123, or satisfactory score onthe English Placement Test.

Course Description:

4 credits, 6 class hours per week: 3 lecture hours and 3 laboratory hours.

BI-201 is the first semester of a one-year course in General Biology. Thiscourse is designed for science majors. It serves as a preparation for the pursuit of abachelor’s degree in Biological Sciences, and equally well as a foundation forprofessional programs (physical therapy, occupational therapy, physician’s assistant,medical laboratory technology, environmental health, medicine etc.). All thesescientific and para-medical programs are rigorous and highly competitive; studentswill need a C or better in BI-201 in order to be admitted.

The course also fulfills the lab science requirement for other students, but isnot recommended, since there are lab science courses designed for the non-scientist,which are less challenging and of more general interest.

Required Books and Materials:

Campbell Biology, (9th Edition), Reece. Pearson/Benjamin Cummings, 2011.

BI-201: General Biology I, Laboratory Manual with Computer Exercises, QCCPress.

Recommended:

Mastering Biology: The textbook web site provides 24/7 review, tutorials,animations and practice tests. Your access code and instructions to register, log in,and use the site are on an insert at the front of the text. If you did not purchase anew copy of the text, you will have to pay $50 for accesswww.masteringbiology.com

Career information: Occupational Outlook Handbook www.bls.gov/oco/describes the job duties, working conditions, education requirements,earnings, and employment prospects for hundreds of jobs grouped by area ofinterest such as, math, science, or nature.

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POLICY ON CHEATING

Instructors of this course are required to implement the College policy regardingcheating on examinations and assignments. For a complete list of the standards ofacademic integrity consult the College Catalog or the Student Handbook. Asynopsis of prohibited conduct is as follows:

1. Obtaining answers to exam questions by looking at devices (e.g. cellphones, calculators), notes or another student’s paper during an exam.

2. Allowing another student to see and copy answers from your papers.

3. Talking or passing notes, information or objects while taking an examination.

4. Writing notes on your table or desk prior to receiving exam papers.

5. Taking an examination for another student or allowing someone else totake an exam for you.

6. Attempting to obtain or disseminate the content of an examination of anykind prior to distribution by the instructor.

7. Copying another person’s ideas, words or data and handing them in asyour own.

Penalties for deviation from these rules of conduct include, but are not limited to:

1) Submission of an Incident Report to the Department Chair and the Deanof Students.

2) Assignment of a failing grade (F) for the work in question.

3) Dismissal from the course and assignment of an F.

4) Expulsion from the college and CUNY.

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Grading Procedures And Criteria:

The final grade is a combination of the grades earned in the lecture and laboratorysegments of the course. The lecture average accounts for 70% and the laboratoryaverage accounts for 30% of the final grade. Laboratory performance is consideredin borderline cases, but no grades are curved. Students are required to pass bothlecture and lab independently. A lecture (or lab) average below 60 automaticallyresults in failure of the course.

Lecture Exams % of Final Grade

4 Unit Exams 56%Final Exam (on Unit V) 14%

70%

Five multiple choice exams (50 minutes) will be given in lecture. None of theseexam grades will be dropped. Make-up exams for absent students are given onlyunder extreme circumstances and at the instructor’s discretion. Make-ups areadministered at the end of the semester and may vary in format from the regularlyscheduled exams. Under no circumstances will a student be permitted to take morethan one make-up exam. Students who miss more than one exam will be assigned afinal grade of INC, WU or F based upon the nature of the circumstances andwhether or not they are passing the course (see the descriptions on the followingpage).

Laboratory Exams % of Final Grade

4 Quizzes (lowest grade dropped) 22.5%Final Exam 7.5%

30%

Five exams will be administered in lab: 4 Written Quizzes + Final Exam. The fourlab quizzes (30 minutes) will include short answers, fill-ins, definitions, problems, andshort essays. At the end of the semester, only your three highest quiz scores willcount toward your final grade. Because of this generous drop policy, there willbe no make-up lab quizzes. The final exam grade is not dropped.

Final letter grades are assigned by the lecturer as follows:

A …………… 96-100 C …………… 74-76A- …………… 90-95 C- …………… 70-73B+ …………… 87-89 D+ …………… 67-69B …………… 84-86 D …………… 64-66B- …………… 80-83 D- …………… 60-63C+ ………… 77-79 F ………… 0-59

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For example:

Exam/Quiz grades AVG Final Gradelecture 70 84 82 78 85 80 80 x 0.7 = 56lab 60 75 82 85 90 83 83 x 0.3 = 25

56 + 25 = 81B-

INC - given under extraordinary circumstances to students who are passing thecourse. All grades for completed exams remain as part of the student’s record, andare incorporated into the final grade. The student has until the end of the followingsemester to make-up the missed exams; NO EXAMS ARE RETAKEN.Note: a student with an INC cannot register for BI-202 or any other course forwhich BI-201 is a prerequisite.

W - assigned by the administration (not the instructor) to a student who hassubmitted the proper form before the end of the official withdrawal period (fromthe fourth to eighth week of the semester).

WU - unofficial withdrawal, assigned for excessive absences (equivalent to an F)

Grade Notification:

CUNY policy prohibits the posting of grades; giving out grades by instructors overthe phone; and distribution of grades by department secretaries. Students can viewtheir grades in CUNYfirst accessible from the College web site www.qcc.cuny.edu

Attendance Policy:

Students are expected to attend all lecture sessions. Text study alone is notsufficient! Many topics are complex and additional material may be introduced inlecture. Because of the accelerated pace of this course, there is little time to catch upon missed work. Excessive absences will result in your becoming hopelessly behind.Laboratory attendance is mandatory and excessive absences will result in a WU(unofficial withdrawal) being assigned for the entire course. An absent student musttake the initiative for remaining up to date in the course and is responsible for allcovered material and assigned work.

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Study Tips

I. Preliminary steps prior to studying:

A. Make a weekly schedule - include classes, work and family obligations. Setflexible priorities. Then, workout a regular pattern or even a written schedulefor study.

B. Read assigned material before class. This reading provides background in thetopics covered and makes it easier to:

a) understand the lecture b) concentrate and take clear concise notes c) ask better questions

C. Attend all classes and arrive on time.

D. Take organized, concise lecture notes:a) keep a separate notebook for biology; a ring binder will allow you torevise & insert material while preserving the lecture sequence

b) take notes in an outline format; use roman numerals for major points,letters for supporting factors and so on

c) write on only one side of the paper, leaving the other side for additions,corrections & comments

d) as you take notes leave a 2 inch margin on the left-hand side for cluewords, questions & comments

E. Review notes as soon as possible after class while the material is still fresh inyou mind.

a) make corrections (spelling, definitions etc.)b) fill in the “blanks” and revise portions as necessary to create a smooth-flowing outlinec) clarify difficult concepts by adding comments & clue words in themarginsd) use underlining, highlighting or asterisks to call attention to importantidease) write down questions that you need to research in the text or askduring the next class

F. Use the text to clarify, reinforce and supplement the material your instructorcovered in class. Reread the text carefully, keeping in mind the learningobjectives (pp. 13-19). Science textbooks contain a lot of information on eachpage and you may find it necessary to read a section a number of times before

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you clearly understand what you have read. This is to be expected in a sciencecourse. Make reading an active process:

a) write brief notes, comments & questions in the marginsb) underline or highlight sparingly & selectively or take brief concise notesc) enrich your notes with information from the text, creating your own“text book”d) be prepared to note where the lecturer disagrees with the book orpresents more up-to-date information

G. Get help if you need it. Ask the instructor to clarify material you do not fullyunderstand.

II. Studying for exams: (begin several days in advance)

A. All textbook reading & lecture note revision must be completed prior tostudying.

B. Find a quiet place to study where you will not be disturbed.

C. Work from your notebook:a) condense & summarize your notes on blank sheets of paperb) review these sheets a little at a time until you have mastered theinformation

D. Try to predict exam questions:a) devise your own questions & compile a list of key termsb) try to answer these questions & explain these terms without looking atyour notebook

E. Practice tests available in the computer lab (p. 20) will help you determine howwell prepared you are. Review your answers and learn why they are corrector incorrect.

F. Evaluate your exam performance by reviewing previous quizzes.

G. Do not study for more than several hours at a time. Take short (15 min.)breaks.

H. Form a study group with two to five students whose goals and objectives aresimilar to yours. The group should meet for at least two hours a week. It isimportant that each member of the group prepare for the session byreviewing, correcting and clarifying his or her notes.

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I. Take advantage of peer tutoring: Tutoring is available in the Student LearningCenter, L-125 (first floor of the library).

J. Cramming is no substitute for continued review.

K. You are responsible for your own learning. No teacher can assume thatresponsibility. Only you can control how well and how completely you study.

Students who succeed in General Biology are those who attend class regularly, askquestions, come to office hours, study outside class both alone and in study groups,make use of campus resources (computer lab, tutorial center, writing center etc.),seek to understand methods and overarching principles rather than specific answers,teach or tutor others, and discuss concepts with fellow students.

Good Luck!

What tutors can do:• Review course outlines and objectives• Clarify information provided by the instructor• Help you understand the textbook and utilize the information it

contains• Help you identify and understand major topics

What are your responsibilities for tutoring?• Prepare for the tutoring session• Have a positive attitude• Understand that the work is your responsibility, not the tutor’s

What tutors cannot do:• Teach you material that you have not read or heard in class• Provide help with graded homework assignments (lab graphing

assignment, pre-labs & lab report). To do so would be a violation ofthe academic honesty policy & you both would suffer consequences.

• Complete work for you

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BI-201 LECTURE SYLLABUSAND

APPROXIMATE SCHEDULE

TextbookLecture Topic Reading Assignment

UNIT I: EVOLUTION & CHEMISTRY (9 lectures)

A. Evolution Chapter 22B. Basic Chemistry & Water Chapter 2 & 3C. Carbon & Macromolecules Chapter 4 & 5

UNIT I EXAM (approximately 2/11-2/15)

UNIT II: CHEMISTRY & CELL STRUCTURE (8 lectures)

A. Macromolecules (continued) Chapter 5B. Biological Membranes Chapter 7C. Organization of the Cell Chapter 6

UNIT II EXAM (approximately 3/11-3/15)

UNIT III: METABOLISM (7 lectures)

A. Metabolism Chapter 8B. Cellular Respiration Chapter 9C. Photosynthesis Chapter 10

UNIT III EXAM (approximately 4/8-4/12)

UNIT IV: CLASSICAL GENETICS (7 lectures)

A. Meiosis Chapter 13B. Mendel & Basic Principles of Heredity Chapter 14C. Chromosomal Basis of Inheritance Chapter 15

UNIT IV EXAM (approximately 4/29-5/3)

UNIT V: MOLECULAR GENETICS (7 lectures)

A. Molecular Basis of Inheritance Chapter 16B. From Gene to Protein Chapter 17C. Gene Regulation & DNA Technology Chapter 18 & 20

FINAL EXAM on UNIT V (week of 5/17-5/23)

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BI-201 LABORATORY SYLLABUS

Lab # ManualPages

Topic TextReference

1 1-11 Scientific Method Ch. 1

2 12-22 pH, buffers & Introduction to PreLab Ch. 3

3 23-351st PreLab dueBiological Molecules Ch. 5

4 36-42Quiz I on labs 1, 2 & 3Movement of Molecules Ch. 8

5 43-55 Microscope and Cell Structure Ch. 7

6 56-632nd PreLab due; Quiz II on labs 4 & 5Enzyme I Ch. 6

7 64-703rd PreLab dueEnzyme II; LabWrite continued Ch. 6

8 71-79Lab Report & 4th PreLab dueGlucose Oxidation - Fermentation Ch. 9

9 80-885th PreLab due; Quiz III on labs 6, 7, 8Photosynthesis Ch. 10

10 89-109 Mitosis Ch. 12, 13

11 110-120Quiz IV on labs 9 & 10Monohybrid Cross; Pedigrees Ch. 14, 15

12 121-122 Genetics; BioLab Fly Ch. 14, 15

13 Hand out Molecular Genetics Ch 16, 20

14Final Exam

on labs 11,12 & 13

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COURSE OBJECTIVES

These learning objectives represent goals to be achieved after reading the textand attending lectures. The objectives are not a cataloging of everything to belearned in each unit. Rather, they emphasize the important facts, topics and conceptsto be covered. They provide a basic framework to which additional material will beadded by the individual lecturer.

UNIT I: EVOLUTION AND CHEMISTRY

Ch. 22 – Descent with Modification : Darwinian Evolution (pp. 452-468)

1. Define and use these terms: natural selection, homology, adaptation, mutation2. Define evolution in your own words.3. List the five observations on which the theory of evolution by natural selection is

based.4. Explain the following evidence for the occurrence of evolution -

artificial selection, fossil record, comparative anatomy, embryology,biogeography, and molecular biology.

5. Describe one case of natural selection in the wild that has been documented byobservation and experimentation.

Ch. 2 – Chemistry of Life (pp. 30-45)

1. Define and use these terms:element, proton, neutron, electron, trace element, Nobel gas, compound, isotope,radioactive, electronegativity, ion, mole, cohesion, surface tension, adhesion,hydrophilic, hydrophobic, solution, solute, solvent, dissociation

2. Describe the structure of an atom; draw and interpret a Bohr model3. Which elements make up 96% of living matter ?4. Define and distinguish between atomic number and atomic mass.5. Explain how electron configuration influences the chemical behavior of an atom.6. Distinguish among ionic, nonpolar covalent, polar covalent, and hydrogen bonds.

Ch. 3 – Water (pp. 46-57)

1. Describe the structure and geometry of a water molecule, and explain whatproperties emerge as a result of this structure.

2. List and explain five characteristics of water that result from hydrogen bonding.

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3. Explain how water’s high specific heat, high heat of vaporization and expansionupon freezing affect both aquatic and terrestrial environments.

4. Explain the basis of the pH scale and compare the properties of acids, bases, andsalts.

5. Using the bicarbonate buffer system as an example, explain how buffers work.

Ch. 4 – Carbon & Molecular Diversity (pp. 58-67)

1. Define and use these terms:isomer, organic compounds, functional groups

2. Describe the importance of the carbon atom to biochemistry.

Ch. 5 – Structure & Function of Large Biomolecules (pp. 68-77)

1. Define and use these terms:monomer, polymer, macromolecule, dehydration synthesis, hydrolysis

2. List the four main classes of biological macromolecules, stating their chemicalelements, subunits and the role they play in living systems.

3. Discuss the structure and importance of monosaccharides, disaccharides andpolysaccharides.

4. Contrast the chemical structure and functions of saturated fats, unsaturated fats,phospholipids, and steroids.

UNIT II: CHEMISTRY & CELL STRUCTURE

Ch. 5 – Biomolecules (continued) (pp. 77-91)

1. Define and use these terms:conformation, denaturation

2. Describe the characteristics and biological functions of proteins.3. Describe the four levels of protein structure.4. Compare the structure and functions of DNA and RNA.

Ch. 7 – Structure 7 Function of Membranes (pp. 125-141)

1. Define and use these terms:phospholipid bilayer, integral proteins, peripheral proteins, selective permeability,carrier-mediated transport, passive transport, active transport, concentrationgradient, hypertonic, hypotonic, isotonic, sodium-potassium pump, endocytosis,exocytosis

2. Describe the Fluid Mosaic Model of the plasma membrane.

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3. Describe factors that affect the selective permeability of a membrane.4. Explain passive transport: diffusion, osmosis and facilitated diffusion.5. List the factors that affect the rate of diffusion.6. Explain how active transport differs from facilitated diffusion.7. List and explain the three types of endocytosis.

Ch. 6 - Tour of the Cell (pp. 94-124)

1. Define and use these terms:cytoplasm, cytosol, chromatin, chromosome, vesicles, smooth ER,rough ER, endomembrane system

2. Distinguish between prokaryotic and eukaryotic cells.3. Describe the structure and function of the following organelles: nucleus, nucleolus,

ribosome, endoplasmic reticulum (ER), Golgi complex, lysosome, peroxisome,mitochondria, chloroplast, amyloplasts, chromoplasts, centriole, cilia, flagella andcell wall.

4. Describe the structure and functions of microtubules, microfilaments andintermediate filaments.

5. Describe the major structural differences between animal and plant cells.6. Describe the structure and function of intercellular junctions found in plant and

animal cells.

UNIT III: METABOLISM

Ch. 8 – Metabolism (pp. 142-162)

1. Define and use these terms:metabolism, catabolic pathways, anabolic pathways, kinetic energy, potentialenergy, entropy, heat, free energy, equilibrium, oxidation, reduction, catalyst,activation energy, substrate, active site, cofactors, coenzymes, feedback inhibition

2. State the First and Second Laws of Thermodynamics and explain how they relateto living things.

3. Compare exergonic and endergonic reactions.4. Describe the function of ATP in the cell.5. Relate the transfer of electrons (or hydrogen atoms) to the transfer of energy.6. Describe the function of enzymes in biological systems.7. Explain the induced fit model of enzyme function.8. Describe how enzyme activity is influenced by enzyme concentration, substrate

concentration, temperature, pH, inhibitors and allosteric regulators.

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Ch. 9 - Cellular Respiration (pp. 163-183)

1. Define and use these terms:cellular respiration, NAD+, FAD, CoA, matrix, cristae, intermembrane space,cytochrome, chemiosmosis, ATP synthase, aerobic, anaerobic, oxygen debt

2. Distinguish between oxidative phosphorylation and substrate-levelphosphorylation.

3. Write an overall reaction for aerobic respiration.4. Name the starting materials and important end products of:

a) glycolysisb) acetyl CoA productionc) Krebs Cycled) electron transport chain

5. Explain how the movement of electrons down the electron transport chain islinked to production of ATP by chemiosmosis.

6. Explain how other nutrients, such as polysaccharides, lipids, and proteins enterinto cellular respiration.

7. Contrast aerobic respiration with yeast fermentation and muscle fermentation.

Ch. 10 - Photosynthesis (pp. 184-205)

1. Define and use the following terms:autotrophic, heterotrophic, stroma, thylakoid membrane, thylakoid space,wavelength, electromagnetic spectrum, chlorophyll a, accessory pigments, P700,P680, photophosphorylation, light reaction, dark reaction, carbon fixation

2. State which colors (wavelengths) of light are most important for photosynthesis,and explain why.

3. Write an overall reaction for photosynthesis.4. Describe Photosystem I and Photosystem II.5. Compare cyclic and noncyclic electron flow.6. Describe the important differences in chemiosmosis between oxidative

phosphorylation in mitochondria and photophosphorylation in chloroplasts.7. Summarize the light reactions and describe where they occur.8. Summarize the Calvin Cycle, include ATP, NADPH, ribulose biphosphate, RuBP

carboxylase (rubisco) and PGAL (G3P).

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UNIT IV: CLASSICAL GENETICS

Ch. 13 - Meiosis (pp. 248-261)

1. Define and use these terms: somatic cell, karyotype, homologous chromosome, haploid, diploid, gamete,

zygote, tetrad, synapsis, polar body2. Distinguish between asexual and sexual reproduction.3. Distinguish among the life cycle patterns of animals, fungi and plants.4. List the phases of meiosis and describe the events characteristic of each phase.5. Describe the key differences between mitosis and meiosis.6. Explain how independent assortment, crossing over and random fertilization

contribute to genetic variation in sexually reproducing organisms.

Ch. 14 – Mendel & the Gene Idea (pp. 262-285)

1. Define and use these terms:P generation, F1 generation, F2 generation, homozygous, heterozygous,autosome, locus, carriers, amniocentesis, chorionic villi sampling

2. Describe Mendel’s experiments and give reasons why he was successful.3. State Mendel’s Laws.4. Use a Punnett square to predict the results of monohybrid and dihybrid crosses,

giving both genotypic and phenotypic ratios.5. Explain what is meant by a test cross and discuss its significance as a genetic tool.6. Explain how phenotype is affected by complete dominance, incomplete

dominance and codominance.7. Define and give examples of multiple alleles, pleiotropy, epistasis, and polygenic

inheritance.8. Describe the inheritance and expression of cystic fibrosis, Tay-Sachs disease,

sickle cell anemia, Huntington’s disease, hemophilia and phenylketonuria (PKU).9. Describe the inheritance of the ABO blood group.

Ch. 15 – Chromosomal Basis of Inheritance (pp. 286-304)

1. Define and use these terms:triplet repeats, linkage, recombinant, Barr body

2. Explain why linkage interferes with independent assortment.3. Describe sex determination in humans.4. Describe the inheritance of a sex-linked gene such as color-blindness.5. Distinguish among nondisjunction, aneuploidy, and polyploidy; explain how these

chromosomal changes occur and describe the consequences.

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6. Distinguish among deletions, duplications, translocations and inversions.7. Describe the chromosomal alterations in the following disorders: Down

Syndrome, Klinefelter syndrome, Turners syndrome, extra Y, triple-X syndromeand cri du chat syndrome.

UNIT V: MOLECULAR GENETICS

Ch. 16 – Molecular Basis of Heredity (pp. 305-324)

1. Define and use these terms:purine, pyrimidine, 3ʹ′ and 5ʹ′ ends, antiparallel, semiconservative replication,nucleoside triphosphate, origin of replication, leading and lagging strands,replication fork, replication bubble, Okazaki fragment

2. Describe and explain the evidence that DNA is the genetic material.3. Describe the structure of a nucleotide.4. Describe the structure of DNA.5. Describe the process of DNA replication and explain the roles of helicase, single

strand binding proteins, DNA polymerase, primase and ligase.

Ch. 17 – From Gene to Protein (pp. 325-350)

1. Define and use these terms:codon, mRNA, promoter, terminator, tRNA, anticodon, rRNA, reading frame,intron, exon, CAP (in RNA), Poly-A tail

2. Explain how RNA differs from DNA.3. Describe the genetic code and explain how the code is degenerate and nearly

universal.4. Explain the process of transcription including initiation, elongation and

termination.5. Explain the process of translation including initiation, elongation and termination.6. Describe how eukaryotic mRNA is processed before it leaves the nucleus.7. Explain why base-pair insertions usually have a greater effect than base pair

substitutions.8. Describe how mutagenesis can occur.

Ch. 18 - Gene Regulation (prokaryotic) (pp. 351-356)

1. Using the trp operon as an example, explain the concept of an operon and thefunction of the operator, repressor and corepressor.

2. Describe how the lac operon functions and describe the role of the inducerallolactase.

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4. Give examples of transcriptional control, posttranscriptional control, translationalcontrol, and posttranslational control of eukaryotic genes.

Ch. 20 – DNA Technology (pp. 396- 398; 405-407; 417-422)

1. Describe and use these terms:restriction enzymes, genetic engineering, cloning vectors

2. List some practical applications of DNA technology.