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Cellular Respiration

Glycolysis

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Page 1: Glycolysis

Cellular Respiration

Page 2: Glycolysis

Energy From Electrons Atom nucleus

Positive Attracts/pulls electrons Potential energy released when nucleus pulls electrons to it (makes bond)

Think of the atomic structure of the following atoms Oxygen (make up the oxygen molecule in cell resp) Hydrogen and Carbon (bonded to each other in glucose) Which has a stronger attraction for electrons? What happens in cell respiration?

Oxygen molecule reacts with glucose Carbon and hydrogen leave each other and become bonded to oxygen's,

creating the carbon dioxide and water produced in cellular respiration The electrons in hydrogen and carbon are pulled toward the nucleus

of the oxygen atoms, thus releasing potential energy Occurs when you burn sugar, lots of energy released almost

instantaneously In cellular respiration, occurs in controlled steps to prevent a massive

release of energy

Page 3: Glycolysis
Page 4: Glycolysis

Electron Transport Chain (etc) Cell respiration releases E in small amounts in the form of

ATP molecules Several steps Oxygen is only involved in the end Electrons=energy Electrons are carried by electron carrier molecules

Electron carrier is a molecule that can accept a pair of high-E electrons and transfer them along with most of their energy to another molecule

Oxygen is the final electron acceptor that joins with hydrogen ions to make water

This transfer of electrons throughout cellular respiration is called the electron transport chain (ETC)

For every transfer of electrons between molecules in the chain, a little E is released

Page 5: Glycolysis
Page 6: Glycolysis

Cellular Respiration A cellular process (part of metabolism) Metabolism

Set of chem. rxns through which an organism builds up or breaks down materials as it carries out life’s processes

C6H12O6 (aq) + 6O2 (g) → 6CO2 (g) + 6H2O (l) Glucose reacts with oxygen to produce carbon

dioxide and water REQUIRES OXYGEN

Aerobic

Page 7: Glycolysis

Cellular Respiration: 3 parts

1. Glycolysis cytoplasm

2. Kreb’s Cycle Mitochondrian

matrix

3. Electron Transport Chain Within the inner

mitochondrial membrane

Page 8: Glycolysis

GlucoseGlycolysis

Cytoplasm

Pyruvic acid

Electrons carried in NADH

Krebs Cycle

Electrons carried in

NADH and FADH2 Electron

Transport Chain

Mitochondrion

Mitochondrion

Page 9: Glycolysis

Glucose(C6H1206)

+Oxygen

(02)

GlycolysisKrebsCycle

ElectronTransport

Chain

Carbon Dioxide

(CO2)+

Water(H2O)

Cellular Respiration

Page 10: Glycolysis

Glycolysis summary endergonicinvest some ATP

exergonicharvest a little ATP & a little NADH

net yield2 ATP2 NADH

4 ATP

ENERGY INVESTMENT

ENERGY PAYOFF

G3PC-C-C-P

NET YIELD

like $$in the bank

-2 ATP

Page 11: Glycolysis

Glycolysis Greek word “glukus” sweet Latin word “lysis” loosening or decomposing Def: the process in which one molecule of glucose is broken in

half, producing two molecules of pyruvic acid (a three-carbon compound)

Takes place outside mitochondria, in cytoplasm of cell Energy releasing process Does NOT require oxygen Requires an investment of 2 ATP molecules at beginning to get

it going These 2 atp’s are like an investment that pays back with interest In order to earn money from a bank, you have to put $$ in

4 molecules of ATP produced at the end of Glycolysis What is the “net” gain?

2 ATPs

Page 12: Glycolysis

NADH production 4 high-E e- are removed and passed to two

electron carriers called NAD+ (nicotinamide adenine dinucleotide) (each NAD+ carries 2 e-)

Each NAD+ molecule accepts a pair of high-E e-

Once e- are accepted, NAD+ becomes NADH, which will transfer e- to other molecules

NAD+ helps pass energy from glucose to other pathways in the cell

Page 13: Glycolysis
Page 14: Glycolysis

Glycolysis Glucose, a six-carbon sugar, receives 2 phosphates from the

first 2 ATPs invested in Glycolysis Glucose now becomes fructose 1,6-biphosphate (highly

energized) Fructose 1,6-biphosphate splits to become two molecules of

CCC-P (glyceraldehyde 3-P) Each of these molecules transfers electrons and hydrogen ions

to NAD+ molecules that come in Accepting two e- and hydrogen ion changes NAD+ to NADH,

which carry electrons to the next part of Glycolysis An inorganic phosphate is added to the CCC-P molecule

changing it to P-CCC-P (1,3-biphosphoglycerate) 2 ADP molecules will come in and snatch off the phosphates

from P-CCC-P and the molecule has now become PYRUVATE or PYRUVIC ACID

Pyruvate is then sent on to the next phase, the Kreb’s Cycle

Page 15: Glycolysis
Page 16: Glycolysis
Page 17: Glycolysis

Reactants and Products of Glycolysis

In 1 glucose 2 ATP 2 NAD+

Out 2 NADH (to ETC) 4 ATP 2 Pyruvates (to Kreb’s cycle) (Net ATPs 2)

Page 18: Glycolysis

Glucose

To the electron transport chain

2 Pyruvic acid