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Mayo School of Continuous Professional Development

Course Director(s)Sean S. Park, M.D., Ph.D.

Edith A. Perez, M.D.

REGISTER ONLINE NOW!http://www.mayo.edu/cme

Mayo School of Continuous Professional Development

Breast, Ovarian, and Lung Cancer: Screening, Diagnosis, and Personalized

Management in 2014

Friday, February 21 and Saturday, February 22, 2014

Mayo Clinic Simulation CenterStabile North Building (8th Floor)

Jacksonville, Florida

COURSE DESCRIPTIONThis interactive two day course has been designed for medical oncologists, radiation oncologists, surgical oncologists, oncology nurses, and healthcare professionals involved in cancer care. General practitioners (internal medicine and family medicine) will have the benefit of a review of the standard of care and new developments in breast, gynecological, and lung cancer screening and therapy. Residents in training and fellows from these specialties are encouraged to attend.

There will be small group interactive special sessions devoted to genetics, radiologic techniques, and diagnostic biopsy steps, pathological concepts, as well as standard and novel therapy. There will be emphasis on molecular diagnosis and individualization of cancer therapy based on state of the art molecular phenotypes.

Participants in the meeting will have the opportunity to learn the most recent management in these areas, while having small group discussions and personal interaction with experts in the field.

COURSE LEARNING OBJECTIVES Upon conclusion of this program, participants should be able to:

• Describe the epidemiology, genetic risk assessment, and pathology of breast cancer

• Recognize the latest therapeutic strategies for breast, gynecological, and colon cancer in women

• Identify current strategies in the systemic therapies for women with breast, gynecological, and lung cancer

• Recognize strategies for innovative research and future treatment of patients with breast, gynecologic and lung cancer

• Identify biospecimen testing options including pathology and next generation gene sequencing

• Demonstrate knowledge of clinical care through case discussion

Attendance at this Mayo course does not indicate or guarantee competence or proficiency in the performance of any procedures which may be discussed or taught in this course.

CREDIT Mayo Clinic College of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Mayo Clinic College of Medicine designates

this live activity for a maximum of 11.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

AOA - This program has been accredited by the American Osteopathic Association for 11.5 credits of AOA Category 2-A.

Other Health Care Professionals - A certificate of attendance will be provided to other health care professionals for requesting credits in accordance with state nursing boards, specialty societies, or other professional associations.

GRANTS AND EXHIBITS At the time of this printing, a complete listing of commercial supporters (financial or in-kind) was not available. Appropriate acknowledgment will be given to all supporters at the time of the meeting.

Exhibits will be available for viewing at all scheduled breaks.

REGISTRATION To register online, visit www.mayo.edu/cme/hematology-and-oncology-2014j629 or complete the attached registration form and return by mail or fax. The registration fee includes tuition, a comprehensive electronic course syllabus, continental breakfasts, break refreshments and buffet lunches. Although it is not Mayo School of Continuous Professional Development (CPD) policy to limit the number of registrants for a course, conference room facilities may necessitate closing of enrollment; therefore, early registration is advised. A letter of confirmation will be sent upon receipt of payment and completed registration form. Please present the confirmation letter when checking in at the meeting registration desk.

CANCELLATION POLICY If you cancel your participation in this course, your registration fee, less a $75 administrative fee, will be refunded when written notification is received by Mayo School of CPD on or before Friday, February 7, 2014 (cme-jax@mayo.edu or fax#: 904-956-3096). No refunds will be made after Friday, February 7, 2014. Canceled registrations are non-transferable.

Mayo School of CPD reserves the right to cancel or postpone any course due to unforeseen circumstances. In the unlikely event Mayo School of CPD must cancel or postpone this course, Mayo School of CPD will refund the registration fee, but is not responsible for any related costs, charges, or expenses to participants, including fees assessed by airline/travel/lodging agencies.

Rick Baehner, M.D.University of CaliforniaSan Francisco, CA

Kimberly L. Blackwell, M.D.Professor of MedicineAssistant Professor of Radiation OncologyDivision of Medical OncologyDirector, Breast Cancer ProgramDuke University Medical Center, Durham, NC

Patricia Cortazar, M.D.U.S. Food and Drug Administration Center for Drug Evaluation and Research Office of Hematology Oncology Products Breast Oncology Group Silver Spring, MD

Mohammed Johanzbeb, M.D.Sylvester Comprehensive Cancer CenterMiami, FL

MAYO FACULTY

MEETING LOCATION Mayo Clinic Simulation CenterStabile North Building (8th Floor)4500 San Pablo RoadJacksonville, FL 32224

Mayo Clinic Simulation Center creates an ideal environment for medical learners to participate in education and training about the most up-to-date techniques and advances. The Center is located on the Mayo Clinic campus in Florida in the Stabile North Building on the 8th floor.

PARKING Parking is available in multiple lots near the Stabile North Building at no charge, as well as in the Mayo patient/visitor ramp adjacent to the Davis Building at $3.00 per day on Friday and no charge on Saturday.

The cost for parking is not included in the registration fee.

TRAVEL/LODGING ACCOMMODATIONS Accommodations are offered in conjunction with the 26.2 with Donna-The National Marathon to Finish Breast Cancer. Book your hotel accommodations at www.breastcancermarathon.com

Lodging arrangements are the sole responsibility of the individual registrant.

Mayo School of CPD is not responsible for expenses incurred by an individual who is not confirmed and for whom space is not available at the meeting. Costs incurred by the registrant such as airline or hotel fees or penalties are the responsibility of the registrant.

Pooja P. Advani, M.B.B.S.Yan W. Asmann, Ph.D. Andrew W. Bowman, M.D., Ph.D.Gerardo Colon-Otero, M.D.Jennifer A. Crozier, M.D. Hillary W. Garner, M.D.Elizabeth A. Johnson, M.D.Minetta C. Liu, M.D.

Alvaro Moreno-Aspitia, M.D.Robert W. Mutter, M.D.Aziza Nassar, M.D.Sean S. Park, M.D., Ph.D.Edith A. Perez, M.D.Jason S. Starr, D.O.E. Aubrey Thompson, Ph.D.

Monica M. Reinholz, Ph.D.Biomarker Strategy; Director, Clinical Studies Translational Diagnostics Ventana Medical SystemsTucson, AZ

Maegan Roberts, MS, CGCGeneDx, Inherited Cancers SpecialistGaithersburg, MD

Sandra M. Swain, M.D.Medical Director, Washington Cancer InstituteMedstar Washington Hospital CenterWashington, D.C.

JoAnne Zujewski, M.D.Senior Medical OncologistCenter for Cancer Research National Cancer InstituteBethesda, MD

GUEST FACULTY

PROGRAM AGENDAFriday, February 21, 2014

8:00 a.m. Registration and Continental Breakfast8:30 Introduction and Pre-Test8:45 New Data of Relevant Inherited Mutations Related to Breast and Ovarian Cancer - Maegan Roberts, MS, CGC

Breast CancerModerator: Sean S. Park, M.D., Ph.D. and Edith A. Perez, M.D. Co-Moderator: Jennifer A. Crozier, M.D.

9:15 & 9:45 Breast Imaging: The Patient Experience Andrew W. Bowman, M.D., Ph.D.9:45 & 9:45 Seed Localization for Nonpalpable Breast Cancer Hillary W. Garner, M.D.

10:15 Break

10:30 The Pathology of Breast Cancer: What is Standard of Care? Aziza Nassar, M.D. Microscope Procedural Lab 11:15 & 11:45 Tissue-Based Companion Diagnostics in Personalized Medicine for Oncology - Monica M. Reinholz, Ph.D.11:15 & 11:45 Gene Expression: Arrays, PCR, and Next Generation Gene Sequencing; What Assays Have Been Created and Where Is This Headed - Rick Baehner, M.D.

12:15 p.m. Break and Pick up Lunch

Molecular Diagnostics for Breast Cancer and RadiationCo-moderator: Pooja P. Advani, M.B.B.S.12:30 Lunch & Learn: RNA Extraction Video1:30 & 2:00 Breast Genomics Tumor Board: Cases 1 & 2 E. Aubrey Thompson, Ph.D., Sandra M. Swain M.D., JoAnne Zujewski, M.D., Rick Baehner, M.D. and Alvaro Moreno-Aspitia, M.D.1:30 & 2:00 Breast Genomics Tumor Board: Cases 3 & 4 Kimberly L. Blackwell, M.D., Yan W. Asmann, Ph.D., Patricia Cortazar, M.D., Monica M. Reinholz, Ph.D. and Minetta C. Liu, M.D.2:30 Radiation in the Setting of Neoadjuvant Therapy for Breast Cancer Robert W. Mutter, M.D.3:00 Novel Radiation Technologies Available to Address Cardiac Toxicity - Sean S. Park, M.D., Ph.D.

3:30 p.m. Adjourn

9:45 a.m. Continental Breakfast

Systemic Therapy for Breast Cancer10:00 Update on Metastatic Breast Cancer by Molecular Classification, With Case Discussions - (4) Tables of 12 - Kimberly L. Blackwell, M.D. 10:30 Update of Adjuvant Therapy for Breast Cancer With Case Discussions (4) Tables of 12 - Minetta C. Liu, M.D.

Gynecologic Cancers11:00 Highlights of Management of GYN Malignancies in 2014 Gerardo Colon-Otero, M.D.

11:45 Break and Pick up Lunch

Novel Considerations for Clinical Trials and New TherapiesNoon Lunch & Learn: Impact of ASCO on Oncology Practice Sandra M. Swain, M.D.12:30 p.m. NCI Perspective on Breast Cancer - JoAnne Zujewski, M.D.

1:00 Clinical Trials in the Era of Personalized Medicine Patricia Cortazar, M.D. Lung CancerCo-moderator: Jason S. Starr, D.O.1:30 Prevention and Optimal Screening for Lung Cancer, Interactive Approach - Elizabeth A. Johnson, M.D.2:00 Biomarker Approaches to Adjuvant Therapy for Lung Cancer Elizabeth A. Johnson, M.D. Case Studies - (4) Tables of 12 2:30 Molecularly Derived Systemic Therapy for Lung Cancer Mohammed Johanzbeb, M.D. Case Studies - (4) Tables of 12

3:00 p.m. Post-Test, Closing Comments and Adjourn Sean S. Park, M.D., Ph.D. and Edith A. Perez, M.D.

Program schedule is subject to change without notice.

Monica M. Reinholz, Ph.D.Biomarker Strategy; Director, Clinical Studies Translational Diagnostics Ventana Medical SystemsTucson, AZ

Maegan Roberts, MS, CGCGeneDx, Inherited Cancers SpecialistGaithersburg, MD

Sandra M. Swain, M.D.Medical Director, Washington Cancer InstituteMedstar Washington Hospital CenterWashington, D.C.

JoAnne Zujewski, M.D.Senior Medical OncologistCenter for Cancer Research National Cancer InstituteBethesda, MD

Saturday, February 22, 2014

(Please print or type all information. You may duplicate this form for multiple registrations.)

First Name

Degree – select all that apply MD/DO PhD PA NP Other

I would like to request special accommodations, indicate specfic need(s) here:

M.I. Last Name

Preferred mailing address

City

Institution

Medical Specialty

Email (NOTE: E-mail is the Mayo School of CPD’s primary form of correspondence.)

Telephone

Mail Form and Payment to:

Mayo School of Continuous Professional Development | 790N Stabile Bldg. | 4500 San Pablo Road Jacksonville, FL 32224|Telephone: (800) 462-9633|Fax: (904) 956-3096

Website: www.mayo.edu/cme|Email: cme-jax@mayo.edu

Zip

Business Telephone

Registration Fees:

Physicians/Scientists – $550

Friday, February 21 - Saturday, February 22, 2014Mayo Clinic Simulation Center/Stabile North Building (8th Floor)

4500 San Pablo Road/Jacksonville, Florida 32224

REGISTRATION FORM 2014J629

State

Expires (Mo/Yr):

Card Number:

Payment Method

q Check Enclosed (Make checks payable to Mayo Clinic Education)

Credit Card: q Visa q MasterCard q Discover

Signature Date

•ONLY AN ELECTRONIC SYLLABUS WILL BE PROVIDED

Type of credit interested in receiving: q AMA/Category 1 q AOA

SPECIALNEEDS

REGISTER ONLINE NOW! www.mayo.edu/cme/hematology-and-oncology-2014j629

FACULTY DISCLOSURE As a provider accredited by ACCME, College of Medicine, Mayo Clinic (Mayo School of Continuous Professional Development) must ensure balance, independence, objectivity and scientific rigor in its educational activities. Course director(s), planning committee, faculty, and all others who are in a position to control the content of this educational activity are required to disclose all relevant financial relationships with any commercial interest related to the subject matter of the educational activity. Safeguards against commercial bias have been put in place. Faculty also will disclose any off-label and/or investigational use of pharmaceuticals or instruments discussed in their presentation. Disclosure of this information will be published in course materials so those participants in the activity may formulate their own judgments regarding the presentation.

Residents, PA’s, NP’s and Retirees – $350

Total Payment Enclosed:

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