Crimean- Congo Hemorrhagic Fever- Turkish Experience

Crimean- Congo Hemorrhagic Fever- Turkish Experience Nursah Basol, M.D.Gaziosmanpasa University, Faculty of Medicine, Department of Emergency MedicineTokat- TURKEY

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The first CCHF case was identified in Tokat in 2002. 4

1944.. first described in Soviet soldiers in the Crimea and was named Crimean fever. 1956.. isolated from a child with similar symptoms and was named Congo virus.

1969 The causative agent of both diseases was shown to be the same virus, and termed Crimean-Congo hemorrhagic fever virus 5

CCHF Virus Single helical RNA virusMember of the Bunyaviridae familyNairovirus group

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Tick Life Cycle

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Transmission Tick bite (genus Hyalomma marginatum)Removing or smashing ticks with bare handsContacting body fluids like blood of infected peopleHandling of tissue, blood or other body fluids of infected animals unprotected.Nosocomial transmissionVertical transmission.

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Pathogenesis

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Epidemiology

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Travelers

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The Data of Turkey12

The Data of Turkey13

GOU Hospital14

Season

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SymptomsFever

Headache

Muscle pain

Loss of appetite

Nausea

Vomiting

Diarrhea

Bleeding

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Symptoms

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SymptomsFatigue (86.2%)Widespread body pain (74.5%)Fever (71.5%)

Headache (68.6%)Nausea and Vomiting (46%)

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Clinical CourseIncubation Period (2-10 days)Prehemorrhagic Period (7 days)Hemorrhagic Period Recovery Period

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Laboratuary

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Laboratuary

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Abdominal Findings

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Pulmonary Findings

Infiltration Hilar PathologyInterstitial Pathology Pleural Thicking Pleural Effusion

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Cutaneous Findings

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Diagnosis

CCHF RT-PCR and/or ELISA IgG and IgM

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AlgorithmSuddenly Onset ofFeverHeadacheCommon Body Pain ArthralgiaFatigueDiarrheaBleedingAt Least 2 of them

Living in an endemic areaHistory of visiting an endemic areaHistory of contacting with animal body fluidsHistory of contacting a patient with CCHF

CBC32

CBC

Plt: < 150.000Wbc: