Mootravaha ksr

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  • 1. Conceptual study ofMootravaha SrotasProf. Dr. K. Shiva Rama PrasadM.D (KC), M.A. Ph.D. (Jyo)doctorksrprasad@gmail.com 01-07-2006 2

2. Doctor I am passing more urine more time what to do? I am getting abdominal bloat and not passing urine what to do? I am getting lots of burning sensation while passing urine, help me. My urine is green in colour. Is it a disease? I get the sensation but not able to pass urine, what to do? All these questions are common for practitioner. What to do? How to understand these problems? What is the natures mystery behind it?doctorksrprasad@gmail.com01-07-20063 3. Natures existence survival phenomenon checks the beings nutrient input and waste material output forms very well before to the birth in the womb. Out of many - first one is dependent upon the water which is a major part of the life existence. We can not think the life with out water inside body and out side in the world.doctorksrprasad@gmail.com 01-07-2006 4 4. The human body contains trillions of cellsbathed in extra-cellular fluid.Cells in the body make mess andgenerate piles of garbage.Most of the organic waste products areremoved and excreted by the urinarysystem, discussed and focused in thissymposia.The water drains the waste from the bodyas URINE and the system concerned to itis Mootravaha srotas.doctorksrprasad@gmail.com 01-07-2006 5 5. Mootra (Urine )The Water of LifeUrine is liquid waste produced by ananimals kidney. It is used to extractwastes from the body in liquid form. Urinecan also play a role in animal behavior.urine - waste fluid secreted by thekidneys and discharged from the bladder.Medically speaking - The fluid anddissolved substances excreted by thekidney.doctorksrprasad@gmail.com01-07-20066 6. There was a King Tymore once he went to forest forhunting. There he miss theroad and only the clone isbehind him. He was thirsty. Hewants the water. Some how the clone get the water and asked the king dear sir, what you can pay for this water, king replied half of my kingdom. OK, if this water doesnt come out, then? The king replied as usual half of my kingdom. Then the clone said to king is it not ridiculous to fight such sort of kingdoms.doctorksrprasad@gmail.com 01-07-20067 7. But for us the excessive or less use of the system both are problematic.The history of drinkingurine for therapeutic purposes dates backat least to the HolyRoman Empire when great urinal trothswere erected in thepublic squares of eachcity-state for residents to both contribute to,and benefit from. doctorksrprasad@gmail.com 01-07-2006 8 8. Urine for Mouth wash, Cure for Jaundice and Antiseptic too ..An 18th century French dentist praisedurine as a valuable mouthwash.In England during the 1860-70s, thedrinking of ones own urine was acommon cure for jaundice.In more modern times, the AlaskanEskimos have used urine as an antisepticto treat wounds.Not only these but many more uses.doctorksrprasad@gmail.com 01-07-2006 9 9. Urine is known to contain minute amounts of proteins made by the body, including medically important ones such as growth hormone and insulin.The idea of using and recycling urine is not new,it is practiced in Ayurveda for long time with theprecautions.There is a $500-million-a-year market for urineingredients. Enzymes of America plans to marketits first major urine product called urokinase, anenzyme that dissolves blood clots and is usedto treat victims of heart attacks.doctorksrprasad@gmail.com01-07-200610 10. Normal functions of theMootravaha srotasRegulating blood volume and bloodpressure by (1) adjusting the volume ofwater lost in the urine,(2) releasing erythropoietin,and(3) releasing renin.doctorksrprasad@gmail.com01-07-2006 11 11. Regulating plasma concentrations ofelectrolytes - sodium, potassium, chloride,and other ions by controlling thequantities lost in the urine and controllingcalcium ion levels by the synthesis ofcalcitriol.doctorksrprasad@gmail.com 01-07-2006 12 12. Contributing to the stabilization of bloodpH - by controlling the loss of hydrogenions and bicarbonate ions in the urine.Conserving valuable nutrients bypreventing their excretion in the urinewhile eliminating organic waste products,especially nitrogenous wastes, such asurea and uric acid.Assisting the liver in detoxifying poisonsand, during starvation, de-aminatingamino acids so that they can be brokendown by other tissues.doctorksrprasad@gmail.com 01-07-2006 13 13. Four fold function Four fold problem Forms of Sroto dusti Atipravrutti Apravrutti Sanga Sira Granthidoctorksrprasad@gmail.com 01-07-200614 14. glucose in urine, Bed-wetting or cessation ofurine production in cardiovascular shock iscommonMany of the body physiology leads and altersthe urine out put.Atipravrutti excess urination as in Prameha,Amavata etc.Apravrutti diminishing urination as inMootrkruchra,doctorksrprasad@gmail.com 01-07-2006 15 15. Sanga - as in MootraghataSira grandhi which indicates the involvementof vascular interventionAll of these are with different aetiology andeven with different components of diseasemanifestationBut the common is the tract Srotas andthe management to the tract along withrectifying pathology is the present task.doctorksrprasad@gmail.com 01-07-2006 16 16. What we drain out ?Urea.Urea is the most abundantorganic waste.We generate roughly 21 g ofurea each day. Most of it isproduced during thebreakdown of amino acids.doctorksrprasad@gmail.com01-07-200617 17. What we drain out ? Creatinine. Creatinine is generated in skeletal muscle tissue by the breakdown of creatine phosphate, a high-energy compound that plays an important role in muscle contraction (Vata activity?). Our body generates roughly 1.8 g of creatinine each day, and virtually all of it is excreted in the urine.doctorksrprasad@gmail.com01-07-2006 18 18. Metabolism and excretion of Creatininedoctorksrprasad@gmail.com 01-07-2006 19 19. What we drain out ?Uric acid.Uric acid is formed by therecycling of nitrogenous bases(Kapha associations?) fromRNA molecules.We produce approximately480 mg of uric acid each day.doctorksrprasad@gmail.com01-07-200620 20. Proteinuriadoctorksrprasad@gmail.com 01-07-2006 21 21. Factors to be noticedVasti in terms of Mootravaha srotas is aSadyahpranahara MarmaExercises (Vyayama) and sex act (Prasanga) Vata activity disturbs the KUB systemsLiquids such as Madya (alcohol) and jala sevana(water consumption) of Kapha concerns alsovitiates the srotasVegadharana enhances (inhibited neuralreflexes) the Vata (Apanavata) is the primefactor to vitiate the Mootravaha srotasWe can not deny in some of the occasions eventhe role of Ca+ ion or other electrolytes.doctorksrprasad@gmail.com 01-07-200622 22. EFFECTS OF NEPHRON LOSS ON RENALEXCRETORY MECHANISMSThe volume of urine excreted (averaging 1.5 L/dor roughly 1 mL/min) represents the sum of twolarge, directionally opposite processesnamely,ultrafiltration of 180 L/d or more of plasmawater (or 125 mL/min) and reabsorption of morethan 99% of this filtrate by transport processesin the renal tubules.While renal blood flow accounts for about 20%of resting cardiac output, the kidneys compriseonly about 1% of total body weight. Thisdisproportionate allocation of cardiac output,greatly exceeding blood flow per gram of brain,heart or liver, is required for the process ofultrafiltrationdoctorksrprasad@gmail.com 01-07-200623 23. Biologic Consequences of Sustained Reductionsin GFRAlthough nephron loss can proceed, to someextent, without equivalent loss of GFR due tothe compensatory mechanisms, determinationof the total GFR of both kidneys remains themost reliable clinical index of overall excretoryfunction.The effects of impaired GFR are to reduce thetotal rate of delivery of solute into theglomerular filtrate.When accompanied by comparably reducedrates of urinary excretion, retention andaccumulation of the unexcreted solute occurs,resulting in increased concentrations of thesubstance in the plasma and other body fluids.doctorksrprasad@gmail.com 01-07-200624 24. EFFECTS OF NEPHRON LOSS ON WATERREABSORPTION IN SURVIVING NEPHRONSTUBULE TRANSPORT OF PHOSPHATEWITH NORMAL AND REDUCED NEPHRONMASSAlterations in Vitamin D MetabolismHyperparathyroidism in Chronic RenalFailureHYDROGEN AND BICARBONATETRANSPORT WITH NORMAL ANDREDUCED RENAL MASSTUBULE POTASSIUM TRANSPORT WITHNORMAL AND REDUCED NEPHRON MASSdoctorksrprasad@gmail.com 01-07-2006 25 25. Transport functions of the various anatomic segments doctorksrprasad@gmail.com 01-07-200626 26. Absorption, metabolism, and excretion of ureadoctorksrprasad@gmail.com 01-07-200627 27. Rhabdomyolysis is - An acute, fulminating, potentially fatal disease of skeletal muscle that entails destruction of skeletal muscle as evidenced by myoglobinemia and myoglobinuria which is an excess urination resultant connected to that of the Vata involvement in Mootravaha srotas. Microalbuminuria in patients with diabetes mellitus is a common situation in KUB system. Such conditions are innumerable to be evaluated from observation based Ayurvedic transformed to Evidence based medicine.doctorksrprasad@gmail.com 01-07-200628 28. Thats all folks doctorksrprasad@sify.comdoctorksrprasad@gmail.com 01-07-200629