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Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Chapter 4: Critically Appraising Knowledge for Clinical Decision
Making
Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
The Need for Critical Appraisal
It is vital to discern biased evidence from unbiased, reliable from unreliable
Practice that is based on flawed evidence cannot be considered EBP
Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Knowledge Sources
In the past, practice was based largely on tradition, logic, and expertise
Research Utilization (RU) movement began to change this
RU emphasized the use of single studies, however
The process for generating practice-based evidence (e.g., quality improvement data) has improved
Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Weighing the Evidence
Practitioners take into account the validity and reliability of the specific evidence
Reliance on inexplicit or inferior knowledge sources (tradition; trial and error) is rapidly becoming unacceptable
Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Knowledge Sources for EBP1. Valid research evidence
The primary basis of clinical decisions
2. Clinical expertise
To best use research by filling in gaps and combining it with practice-based evidence to tailor clinical actions for individual patients’ contexts
3. Patient choices and concerns
For determining the acceptability of evidence-based care to the individual patient
• The main criterion is certainty
Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Question
Which of the following sources of knowledge would a nurse prioritize when determining the turning schedule for an immobilized patient?
a. The traditional practice on the unit
b. The nurse’s knowledge of skin breakdown
c. The preferences of the patient and the patient’s family
d. A clinical practice guideline for preventing skin breakdown
Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Answer
d. A clinical practice guideline for preventing skin breakdown
Rationale: EBP encompasses patient preferences and the clinical expertise of individual practitioners, but the primary source of knowledge is research evidence. Clinical practice guidelines synthesize this evidence in order to guide practice.
Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Rating the Strength of Evidence
Not necessarily synonymous with “hierarchy of evidence”
High-level study design does not necessarily mean high quality
Grading the strength of a body of evidence addresses three domains – quality, quantity, and consistency
Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Rating the Strength of a Body of Evidence Quality: the extent to which a study’s design, conduct,
and analysis has minimized selection, measurement, and confounding biases (internal validity)
Quantity: the number of studies that have evaluated the question, overall sample size across all studies, magnitude of the treatment effect, strength from causality assessment, such as relative risk or odds ratio
Consistency: whether investigations with both similar and different study designs report similar findings (requires numerous studies)
Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
What is Meant by “Evidence”
Research evidence
Clinical knowledge gained via the individual practitioner’s experience
Patients’ and practitioners’ preferences
Basic principles from logic and theory
Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Question
Tell whether the following statement is true or false.
A post-operative patient’s statement that Dilaudid (hydromorphone) has been ineffective in treating her pain can be considered a form of evidence.
Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Answer
True
Rationale: Patient preferences and experiences are an important consideration and are a form of evidence. While the patient’s preference does not likely constitute the “final word” on treatment choices, it must be weighed carefully and integrated into the nurse’ choice of intervention.
Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Internal Evidence
Evidence that is generated by outcomes management, quality improvement, or EBP implementation projects
Aimed at improving outcomes at the site where improvement efforts are conducted
Quality Indicator Systems:
AHRQ National Healthcare Quality Report
National Quality Forum (NQF)
National Database of Nursing Quality Indicators® (NDNQI®)
Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Question
Tell whether the following statement is true or false.
Internal evidence is characterized by findings that are applicable and generalizable to multiple practice settings.
Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Answer
False
Rationale: Unlike external evidence, the generation of internal evidence is intended to improve clinical practice and patient outcomes within the local setting that it is conducted.
Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins
Combining Internal and External Evidence The PDSA Cycle
1. Plan: Plan the change and observation
2. Do: Try out the change on a small scale
3. Study: Analyze the data and determine what was learned
4. Act: Refine the change based on what was learned and repeat the testing