Obagi Gentle Rejuvenation Skin Care

The New Look of Calm

Gentle Rejuvenation™

ONLY FROM

Gentle Rejuvenation System:

The Obagi® Gentle Rejuvenation System is a gentle and effective skin care regimen featuring unique, clinically proven ingredients and exclusive technologies.

References: 1. McCall-Perez F, Stephens TJ, Herndon Jr JH. Efficacy and tolerability of a facial serum for fine lines, wrinkles, and photodamaged skin. J Clin Aesthet Dermatol. 2011;4(7):51-54. 2. McCullough JL, Weinstein GD. Clinical study of safety and efficacy of using topical kinetin 0.1% (Kinerase® to treatphotodamaged skin. Cosmet Dermatol. 2002;15(9):29-32. 3. Cruz Jr PD, Reece BT. A clinical study of topical zeatin (0.10%, 0.025%) for improving the appearance of photo damaged skin (RCTS Study #1837).12-week final analysis, September 2005. OMP, Inc. Data on file. 4. Rattan SIS, Sodagam L. Gerontomodulatory and youth-preserving effects of zeatin on human skin fibroblasts undergoing aging in vitro. Rejuvenation Res. 2005;8(1):46-57. 5. Katz BE, Bruck MC. Efficacy and tolerability of kinetin 0.1% cream for improving the signs of photoaging in facial and neck skin. Cosmet Dermatol. 2006;19(12):736-741. 6. Wu JJ, Weinstein GD, Kricorian GJ, Kormeili T, McCullough JL. Topical kinetin 0.1% lotion for improving the signs and symptoms of rosacea. Clin Exp Dermatol. 2007;32(6):693-695. 7. Dow Pharmaceutical Sciences, Inc. In vitro release of kinetin and zeatin from Prosome Delivery System (study protocol #2875-121). September 12, 2011. OMP, Inc. Data on file. 8. Skin Care Exploratory Final Report, June 28, 2013. OMP, Inc. Data on file.

Overview

Gentle Rejuvenation is ideal for patients with varying degrees of skin aging concerns

• Dry skin and sensitive skin 1,2

• Mild-to-moderate photodamage and hyperpigmentation 1-3

• The appearance of fine lines and wrinkles 1-3

• Concerns about exploring more aggressive treatments

Gentle Rejuvenation System: Overview

The Kinetin-Zeatin Complex in Gentle

Rejuvenation formulations provides plant-sourced natural growth factors that have demonstrated efficacies in:

• Improving the appearance of sun-damaged and prematurely aged skin 1,4,5

• Promoting healthy rejuvenated, youthful-looking skin 1-3

Here you can see how key ingredients Kinetin and Zeatin visibly improve the appearance of fine wrinkling, blotchiness

and skin texture.

*Study results for twice-daily application of topical Kinetin 0.1%.†Photos have not been retouched. Results may vary.

‡Study results for twice-daily application of topical Zeatin 0.1%.

Gentle Rejuvenation System: Clinical Action

*Study results for twice-daily application of topical Kinetin 0.1%.†Photos have not been retouched. Results may vary.

The Unique Efficacy of the Kinetin-Zeatin Complex

In clinical studies, Kinetin 0.1%:

• Increased skin’s ability to retain moisture by 26% over 24 weeks2

• Diminished spots by an average of 60%5

• Improved mottled hyperpigmentation by 27% over 24 weeks2

• Significantly reduced facial erythema by 32%8

• Showed moderate-to-marked improvement in overall appearance and symptoms associated with rosacea in a most patients6


‡Study results for twice-daily application of topical Zeatin 0.1%.†Photos have not been retouched. Results may vary.

Clinical studies with Zeatin 0.1% demonstrated improvements in:

• Skin roughness by 86%6

• Fine lines and wrinkles by 34%3

• Mottled hyperpigmentation by 25%3

• Zeatin was also shown to have slowed down fibroblast aging (in vitro), which resulted in a youth-preserving effect4


The exclusive Prosome Delivery System transports the Kinetin-Zeatin Complex deep into the skin7

• Prosomes encapsulate nearly twice the amount of ingredients compared to conventional liposome delivery

• They release the Kinetin-Zeatin Complex slowly, over a 12 hour period, to help improve the visible signs of aging


Obagi® Gentle Rejuvenation is the ideal system for patients with sensitive skin who:

• Are CONCERNED about premature aging

• Have visible signs of the CONDITION

• Are pregnant, nursing, allergic or won’t COMMIT to more aggressive therapies

Gentle Rejuvenation System: The 3 C’s

The Gentle Rejuvenation System features a core portfolio of advanced skin care products for daily use to cleanse, moisturize, protect and rejuvenate.

Gentle Rejuvenation System: Products


• Gently removes makeup and everyday impurities

• Cleanses while soothing skin

• Rinses cleanly to leave skin feeling comfortable and soft.


• Non-irritating moisturizing formulation

• Contains plant-derived growth factors Kinetin & Zeatin

• Proven to improve the texture, tone and blotchiness in sun-damaged skin

• Leaves the complexion feeling smooth and soft

• For sensitive and all skin types, is non-comedogenic, hypoallergenic


• Helps provide protection against harmful UVA and UVB rays

• Decreases the risk of skin damage and early signs of aging

caused by the sun

• Fortified with 10% L-ascorbic acid (Vitamin C)


• With ingredients proven to improve the appearance of sun-damaged skin for a more healthy, youthful look

• Harnesses the power of peptides plus the Kinetin-Zeatin Complex

• Provides deep hydration during sleep, allowing exclusive ingredients and technologies to gently rejuvenate skin’s appearance as it complements the body’s natural nightly repair process

For added customization

these stand alone products

can be incorporated into your patients’ programs:



• Diminishes redness, itching burning and stinging that are common in compromised skin*

• Formulated with plant-derived growth factors Kinetin and Zeatin

* Not intended to treat underlying skin disease or dermatoses


• An innovative serum that helps complement cellular turnover and skin’s natural repair process

• Includes plant-derived natural growth factors Kinetin & Zeatin, and Swiss apple stem cell extract


• Protects skin from damaging rays of the sun

• Moisturizes and helps correct visible signs of photoaging

• Gently rejuvenates skin’s appearance


• Noticeably improves the appearance of wrinkles around the delicate eye area

• Gently rejuvenates skin’s appearance and helps improve the visible signs of photoaging

In a nationwide consumer survey, 100% of Gentle Rejuvenation users were either extremely or very satisfied with the products.8

• 92% of users felt the products purified their skin

• 88% of users felt the products made their skin look younger

• 82% of users felt the products rejuvenated the appearance of their skin

Gentle Rejuvenation System: User Satisfaction

For more information about Gentle

Rejuvenation products, how they work,

frequently asked questions, clinical results,

protocol for use and individual product

profiles, click on the links below or visit:

www.obagi.com/patients/product-line/Gentle-Rejuvenation

www.Obagi.com/professional

or call 1.800.636.7546

Gentle Rejuvenation System: More Information

Health & Medicine

Obagi Gentle Rejuvenation Skin Care