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LOOK CLOSER at the complete picture with CGM Quick 3 Step Guide 1-2-3 to interpret iPro™2 Professional CGM Report India Medtronic Pvt. Ltd. 1241 Solitaire Corporate Park, Bldg. 12, 4th Floor, Andheri-Ghatkopar Link Road, Andheri (E), Mumbai 400 093 Tel: +91 22 3307 4700/01/02/03 | Fax: +91 22 3307 4704 | e-mail: [email protected] Simple 2 Start. Easy 2 Evaluate. Pump therapy is simple for you and your patients Your partner for diabetes care Indications for Insulin Pump Therapy Ü High insulin requirements Ü Fear of Hypoglycemia Ü Complications associated with diabetes Ü Missed injections Ü Desire for improved lifestyle / flexibility Ü Elevated A1C Ü Glycemic fluctuations Ü Dawn phenomenon Ü Insulin resistance or glucose toxicity Ü Weight concerns Ü Gestational or pregnancy with type 2

Quick guide i pro2

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Page 1: Quick guide i pro2

LOOK CLOSERat the complete picture with CGM

Quick 3 Step Guide1-2-3

to interpret iPro™2 Professional CGM Report

India Medtronic Pvt. Ltd.1241 Solitaire Corporate Park, Bldg. 12, 4th Floor, Andheri-Ghatkopar Link Road, Andheri (E), Mumbai 400 093Tel: +91 22 3307 4700/01/02/03 | Fax: +91 22 3307 4704 | e-mail: [email protected]

Simple 2 Start.Easy 2 Evaluate.

Pump therapy is simple foryou and your patientsYour partner for diabetes care

Indications for Insulin Pump Therapy

Ü High insulin requirements

Ü Fear of Hypoglycemia

Ü Complications associated with diabetes

Ü Missed injections

Ü Desire for improved lifestyle / flexibility

Ü Elevated A1C

Ü Glycemic fluctuations

Ü Dawn phenomenon

Ü Insulin resistance or glucose toxicity

Ü Weight concerns

Ü Gestational or pregnancy with type 2

Page 2: Quick guide i pro2

Evaluate Pre-Prandial – (before meals)

Evaluate Post-Prandial – (2 to 3 hours after meals)

Evaluate Overnight – (12 am to 6 am)

Close Examinationof 3 Critical Periods

Daily Overlay

Help IdentifyCause and Effect

Quick Review ofGlucose Excursionsor Trends

3 Simple Steps

Support ReportInterpretation withCritical Patient Information

3PO

ST-PRA

NDIAL

Hyp

erglycem

ia3

POST-PRA

NDIAL

Hyp

oglycemia

1OVE

RNIGHT

Hyp

erglycem

ia1

OVE

RNIGHT

Hyp

oglycemia

2PR

E-PR

ANDIAL

Hyp

oglycemia

2PR

E-PR

ANDIAL

Hyp

erglycem

ia

This Guide is intended to provide healthcare professionals a simple 3 Step Methodology to interpret iPro™2 professional continuous glucose monitoring (CGM) reports.

You may use the information in the report to adjust therapies and/or suggest lifestyle changes for your patients. It is recommended that you make only one or two adjustments for your patient at a time to better understand the effect of each change on his/her glucose control.Note: The graphs shown in this guide are recreated artwork to illustrate glucose patterns. They are not produced by the actual software.

Note:

Patient Log Sheet

Simple 2 Start.Easy 2 Evaluate. 3 Simple Reports

Supported by Patient Log Sheet

Daily Summary

Overlay by Meal

Time BG Meal (food/drink) Medication Dosage Activity Duration

Dat

e:

Time BG Meal (food/drink) Medication Dosage Activity Duration

Dat

e:

Time BG Meal (food/drink) Medication Dosage Activity Duration

Dat

e:

Page 3: Quick guide i pro2

Overnight Period - Hypoglycemia (12 am – 6 am)

Simple 2 Start.Easy 2 Evaluate.

3PO

ST-PRA

NDIAL

Hyp

erglycem

ia3

POST-PRA

NDIAL

Hyp

oglycemia

1OVE

RNIGHT

Hyp

erglycem

ia1

OVE

RNIGHT

Hyp

oglycemia

2PR

E-PR

ANDIAL

Hyp

oglycemia

2PR

E-PR

ANDIAL

Hyp

erglycem

ia

Ÿ Decrease dose of oral medication which may affect nocturnal glucose

Ÿ

be too highDose of oral medication may

Ÿ

pump at night or basal insulin dose

Decrease basal rate on insulin

Ÿ

medication which may affect nocturnal glucose

Decrease dose of oral

Ÿ

medication or insulin which may affect nocturnal glucose

Ÿ Decrease basal rate with use of temp basal feature on insulin pump at night

Ÿ Educate patient on effects of exercise on glucose

Decrease dose of oral

Ÿ

insulin may be too highBasal rate or long acting basal

Ÿ

be too highDose of oral medication may

Ÿ

physical activityPrior evening exercise or

Ÿ Prior evening alcohol use Ÿ

alcohol use on glucoseEducate patient on effects of

Ÿ

pump at night or basal insulin dose

Decrease basal rate on insulin

Ÿ

pump at night or basal insulin dose during periods of fasting

Decrease basal rate on insulin

Ÿ

insulin may be too highBasal rate or long acting basal

Ÿ Fasting

Potential Causes ConsiderationsUse “Overlay By Meal” [Night Time Sensor Data]

Nocturnal Hypoglycemia

400

300

200

100

40

0

Mon Tue Wed Thu Fri Sat Average

11:00p 12:00a 1:00a 2:00a 3:00a 4:00a 5:00a 6:00a

TargetRange

..........

....................................... .............................................................................. . ....70

Night Time Sensor Data (mg/dL)

Rebound Hyperglycemia

400

300

200

100

40

0

Mon Tue Wed Thu Fri Sat Average

11:00p 12:00a 1:00a 2:00a 3:00a 4:00a 5:00a 6:00a

TargetRange

70

............................................ . .................... . .........

.........

..................

............

Night Time Sensor Data (mg/dL)

Page 4: Quick guide i pro2

Ÿ

larger dinner with high fat content

Late evening snack/dinner or

Potential Causes ConsiderationsUse “Overlay By Meal” [Night Time Sensor Data]

Ÿ

meal (i.e. fat and quantity) and dinner insulin bolus

Ÿ If on insulin pump, consider dual wave bolus

Evaluate previous evening

Ÿ

medicationInadequate dose of oral

Ÿ

acting basal insulinInadequate basal rate or long

Ÿ Variable exercise pattern

Ÿ Variable sleep pattern

Ÿ

medication which would affect fasting glucose

Increase dose of oral

Ÿ

pump at night or basal insulin dose

Increase basal rate on insulin

Ÿ

time / intensity to test glycemic response

Use standardized exercise

Ÿ

days to better understand the relationship between activity and glucose control (Use “Daily Summary” and “Patient Log Sheet”)

Review excursions for specific

Ÿ

timeImprove regularity of sleep

Simple 2 Start.Easy 2 Evaluate.

Overnight Period - Hyperglycemia (12 am – 6 am)

3PO

ST-PRA

NDIAL

Hyp

erglycem

ia3

POST-PRA

NDIAL

Hyp

oglycemia

1OVE

RNIGHT

Hyp

erglycem

ia2

PRE-PR

ANDIAL

Hyp

oglycemia

2PR

E-PR

ANDIAL

Hyp

erglycem

ia

Page 5: Quick guide i pro2

Ÿ

be too highDose of oral medication may

Potential Causes ConsiderationsUse “Overlay By Meal”

Ÿ

medication which would affect pre-meal glucose

Decrease dose of oral

Ÿ

insulin may be too highBasal rate or long acting basal

Ÿ

may be too highInsulin bolus with last meal

Ÿ Exercise or physical activity

Ÿ

pump prior to meal or basal insulin dose

Decrease basal rate on insulin

Ÿ

prior mealDecrease insulin bolus with

Ÿ

medication or insulin

Ÿ Decrease basal rate with use of temp basal feature on insulin pump

Ÿ Educate patient on effects of exercise on glucose

Decrease dose of oral

Ÿ

“Daily Summary” and “Patient Log Sheet”)

Review previous meal (Use

Simple 2 Start.Easy 2 Evaluate.

Pre-Prandial Periods - Hypoglycemia (Breakfast - Lunch - Dinner)

3PO

ST-PRA

NDIAL

Hyp

erglycem

ia3

POST-PRA

NDIAL

Hyp

oglycemia

2PR

E-PR

ANDIAL

Hyp

oglycemia

2PR

E-PR

ANDIAL

Hyp

erglycem

ia

Page 6: Quick guide i pro2

Ÿ

acting basal insulinInadequate basal rate or long

Potential Causes ConsiderationsUse “Overlay By Meal”

Ÿ

observed hyperglycemia period or basal insulin dose

Increase basal rate prior to

Ÿ

last mealInadequate insulin bolus from

Ÿ

medicationInadequate dose of oral

Ÿ Variable exercise pattern

Ÿ

insulin regimenNon compliant to oral or

Ÿ

prior mealIncrease insulin bolus with

Ÿ

medication which would affect pre-meal glucose

Increase dose of oral

Ÿ

medication with excursion (Use “Daily Summary”and “Patient Log sheet”)

Connect behavior and

Ÿ

time/intensity prior to meal to test glycemic response

Use standardized exercise

Ÿ

complianceEducate patient on

Ÿ

days to better understand the relationship between activity and glucose control (Use “Daily Summary” and “Patient Log Sheet”)

Review excursions for specific

Simple 2 Start.Easy 2 Evaluate.

Pre-Prandial Periods - Hyperglycemia (Breakfast - Lunch - Dinner)

3PO

ST-PRA

NDIAL

Hyp

erglycem

ia3

POST-PRA

NDIAL

Hyp

oglycemia

2PR

E-PR

ANDIAL

Hyp

erglycem

ia

Page 7: Quick guide i pro2

3PO

ST-PRA

NDIAL

Hyp

erglycem

ia3

POST-PRA

NDIAL

Hyp

oglycemia

Simple 2 Start.Easy 2 Evaluate.

Post-Prandial Periods - Hypoglycemia (Breakfast - Lunch - Dinner)

Ÿ

be too highDose of oral medication may

Potential Causes ConsiderationsUse “Overlay By Meal”

Ÿ

medication which would affect post-prandial glucose

Decrease dose of oral

Ÿ

highPre-meal bolus may be too

Ÿ

activityPrior exercise or physical

Ÿ Delayed food absorption

Ÿ

bolus which would affect post-prandial glucose

Decrease pre-meal insulin

Ÿ

medication or insulin

Ÿ Decrease basal rate with use of temp basal feature on insulin pump

Ÿ Educate patient on effects of exercise on glucose

Decrease dose of oral

Ÿ

“Daily Summary” and “Patient Log Sheet”)

Review previous meal (Use

Page 8: Quick guide i pro2

Ÿ

medicationInadequate dose of oral

Potential Causes ConsiderationsUse “Overlay By Meal”

Ÿ

medication which would affect post-prandial glucose

Increase dose of oral

Ÿ

(this could include an inadequate dose of correction insulin)

Inadequate pre-meal bolus

Ÿ

and quantityVariable meal composition

Ÿ Variable exercise pattern

Ÿ

insulin regimenNon compliant to oral or

Ÿ

bolusIncrease pre-meal insulin

Ÿ

low fat meal to test glycemic response

Ÿ Count carbohydrates , if on insulin with meals

Use standardized known carb,

Ÿ

time/intensity to test glycemic response

Use standardized exercise

Ÿ

complianceEducate patient on

Ÿ

days to better understand the relationship between activity and glucose control (Use “Daily Summary” and “Patient Log Sheet”)

Review excursions for specific

Simple 2 Start.Easy 2 Evaluate.

3PO

ST-PRA

NDIAL

Hyp

erglycem

ia

Post-Prandial Periods - Hyperglycemia (Breakfast - Lunch - Dinner)