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Skin Damage Happens. Repairogen Can Help.
OUR MISSION
To develop the leading DNA-based skin repair solution that improves skin health
and appearance.
Investor Presentation | Copyright (C) January 2016
WHY THIS MATTERS
Various factors in the environment, such as UV radiation and pollution, are constantly bombarding our skin and damaging our skin’s
DNA, causing death and destruction to our skin cells.
Investor Presentation | Copyright (C) January 2016
OUR INNOVATIVE SOLUTION
Repairogen’s screening of over 150,000 naturally occurring compounds has identified
multiple new Natural Actives that can penetrate the skin and
significantly reduce multiple signs of premature aging. Natura
l Actives
Multi-Function
al
Skin Penetrabl
e
Investor Presentation | Copyright (C) January 2016
EVIDENCE OF SKIN REPAIR
12012 Hours
63%
% CPD DNA
40
60
80
100
200mJ/cmVehicle Control
20mJ/cm UV+RGN0001 1nM
120
47%
% CPD DNA
40
60
80
100
200mJ/cmVehicle Control
20mJ/cm UV+RGN0001 1nM
24 Hours
Repairogen’s synthetic actives significantly reduced DNA damage in skin after UV exposure
in a reconstructed human skin model.
Investor Presentation | Copyright (C) January 2016
EVIDENCE OF SKIN CANCER PROTECTION
100
50
0
Skin Cancer Free
Weeks of UV irradiation
>90% of mice in test did not develop skin cancer
Test Group
Control Group
10 20 30 40 50
Investor Presentation | Copyright (C) January 2016
No other skin repair mechanism has demonstrated comparable DNA-repair activity.
ANTI-AGING SKIN CARE MARKET
2.5
Spen
d in
Bi
llions
$
0.5
1.0
1.5
2.0
2010
Investor Presentation | Copyright (C) January 2016
Premium facial2011 2012 2013 2014
Premium anti-aging skin care products represent the fastest growing segment (5 year CAGR
of 34%) of the skin care market.
Source: Euromonitor, 2015.
DERMATOLOGISTS WANT REPAIROGEN
… Among 27 dermatologists surveyed … 63% would recommend Repairogen … to 40% of their patients
Investor Presentation | Copyright (C) January 2016 Some of the practices where dermatologistswere surveyed.
EXCEPTIONAL TEAM
Frank Borchetta, JDCEO
Louis Walcer, MBADirector Cornell University McGovern Center Incubator
Nava Dayan, PhDScientific Advisor and Consultant
Senior Management Team
Michael Boice, PhDCSO
Jesse SandovalDirector of Sales
Advisors
Confidential Investor Presentation | March 2015 | Copyright (C)
Frank Borchetta [email protected]+1 (240) 988 2558
Michael Boice, [email protected]+1 (520) 419 2416
