MECHANICAL VENTILATION

Soumya Ranjan Parida

Basic B.Sc. Nursing 4th year

Sum Nursing College

Presentation

Different settings to consider

Monitoring of the patient

Different type of patientCOPD, AsthmaARDS

Trouble shooting

Ventilator settings

Ventilator settings

1. Ventilator mode

2. Respiratory rate

3. Tidal volume or pressure settings

4. Inspiratory flow

5. I:E ratio

6. PEEP

7. FiO2

8. Inspiratory trigger

CMV

A/CV

SIMV

PSV(pressure support ventilation)

Spontaneous inspiratory efforts trigger the ventilator to provide a variable flow of gas in order to attain a preset airway pressure.

Can be used in adjunct with SIMV.

Respiratory Rate

1. What is the pt actual rate demand?

Tidal Volume or Pressure setting

Maximum volume/pressure to achieve good ventilation and oxygenation without producing alveolar overdistention

Max cc/kg? = 10 cc/kg

Some clinical exceptions

Inspiratory flow

Varies with the Vt, I:E and RR

Normally about 60 l/min

Can be majored to 100- 120 l/min

I:E Ratio

1:2

Prolonged at 1:3, 1:4, …

Inverse ratio

FIO2

The usual goal is to use the minimum Fio2 required to have a PaO2 > 60mmhg or a sat >90%

Start at 100%

Oxygen toxicity normally with Fio2 >40%

Inspiratory Trigger

Normally set automatically

2 modes:

Airway pressureFlow triggering

Positive End-expiratory Pressure (PEEP)

What is PEEP?

What is the goal of PEEP?

Improve oxygenation

Diminish the work of breathing

Different potential effects

PEEP

What are the secondary effects of PEEP? Barotrauma Diminish cardiac output

Regional hypoperfusion NaCl retention Augmentation of I.C.P.? Paradoxal hypoxemia

PEEP

Contraindication:No absolute CI

BarotraumaAirway traumaHemodynamic instability I.C.P.?Bronchospasm?

PEEP

What PEEP do you want?

Usually, 5-10 cmH2O

Monitoring of the patient

Look at your patient

Question your pt

Examine your pt

Monitor your pt

Look at the synchronicity of your pt breathing

Pressures

Compliance pressure (Pplat)

Represent the static end inspiratory recoil pressure of the respiratory system, lung and chest wall respectively

Measures the static compliance or elastance

PplatMeasured by occluding the ventilator 3-5 sec at the end of inspiration

Should not exceed 30 cmH2O

Peak Pressure (Ppeak)

Ppeak = Pplat + Pres

Where Pres reflects the resistive element of the respiratory system (ET tube and airway)

PpeakPressure measured at the end of inspiration

Should not exceed 50cmH2O?

Auto-PEEP or Intrinsic PEEP

What is Auto-PEEP?

Normally, at end expiration, the lung volume is equal to the FRC

When PEEPi occurs, the lung volume at end expiration is greater then the FRC

Auto-PEEP or Intrinsic PEEP

Why does hyperinflation occur?

Airflow limitation because of dynamic collapse

No time to expire all the lung volume (high RR or Vt)

Expiratory muscle activityLesions that increase expiratory resistance

Auto-PEEP or Intrinsic PEEP

Auto-PEEP is measured in a relaxed pt with an end-expiratory hold maneuver on a mechanical ventilator immediately before the onset of the next breath

Auto-PEEP or Intrinsic PEEP

Adverse effects:

Predisposes to barotrauma Predisposes hemodynamic compromises Diminishes the efficiency of the force

generated by respiratory muscles Augments the work of breathing Augments the effort to trigger the ventilator

Different types of patient

COPD and Asthma

Goals:

Diminish dynamic hyperinflationDiminish work of breathingControlled hypoventilation

(permissive hypercapnia)

Diminish DHI

Why?

Diminish DHI

How?Diminish minute ventilation

Low Vt (6-8 cc/kg)Low RR (8-10 b/min)Maximize expiratory time

Diminish work of breathing

How: Add PEEP (about 85% of PEEPi)

Applicable in COPD and Asthma.

Controlled hypercapnia

Why?

Limit high airway pressures and thus diminish the risk of complications

Controlled hypercapnia

How?

Control the ventilation to keep adequate pressures up to a PH > 7.20 and/or a PaCO2 of 80 mmHg

Controlled hypercapnia

CI:Head pathologiesSevere HTNSevere metabolic acidosisHypovolemiaSevere refractory hypoxiaSevere pulmonary HTNCoronary disease

A.R.D.S.

Ventilation with lower tidal volume as compared with traditional volumes for acute lung injury and the ARDS

The Acute Respiratory Distress Syndrome Network

N Engl J Med 2000;342:1301-08

Methods

March 96 – March 9910 university centersInclusion:Diminish PaO2Bilateral infiltrateWedge < 18

ExclusionRandomized

MethodsA/C 28d or weaning2 groups: 1. Traditional Vt (12cc/kg) 2. Low Vt (6cc/kg)

End point: 1. Death 2. Days of spontaneous breathing 3. Days without organ failure or barotrauma

ResultsThe trails were stopped after 861 pt because of lower mortality in low Vt group

Trouble Shooting

Trouble Shooting

Doctor, doctor, his pressures are going up!!!

What is your next step?

Trouble Shooting

1. Call the I.T., he will take care of it!

2. Where is the staff?

3. I dont know this pt, and run!

4. Ask which pressure is going up

Trouble Shooting

Ppeak is up

Look at your Pplat

Trouble Shooting

If your Pplat is high, you are faced with a COMPLIANCE problem

If your Pplat is N, you are faced with a RESISTIVE problem

DD?

Trouble Shooting

Trouble Shooting

Doctor, doctor, my patient is very agitated!

What is your next step?

Trouble Shooting

1. Give an ativan to the nurse!

2. Give haldol 10mg to the patient!

3. Take 5mg of morphine for yourself!

4. Look at your pt!

Trouble Shooting

At the time of intubation, fighting is largely due to anxiety

But what do you do if pt is stable and then becomes agitated?

Trouble Shooting

1. Remove pt from ventilator

2. Initiate manual ventilation

3. Perform P/E and assess monitoring indices

4. Check patency of airway

5. If death is imminent, consider and treat most likely causes

6. Once pt is stabilized, undertake more detailed assessement and management

Trouble Shooting

ConclusionType of patient Tidal Volume RR PEEP FIO2 Ins. Flow I:E Note Note

Normal 10 cc/kg 10 to 12 0 to 5 100%. 60 l/min 1:2.

ARDS 6 cc/kg 10 to 12 5 to 15 100%. 60 l/min 1:2.

COPD 6 cc/kg 10 to 12 5 to 10 100%. 100 to 120 1:3 to 1:4 PH>7.2PCO2 <80 mmhgTrigger to consider

Trauma 10 cc/kg 10 to 12 0. 100%. 60 l/min 1:2.

Pediatric 8-10 cc/kg Varies age 3 to 5 100%. 60 l/min 1:2. Trigger to consider