Session 3 - big (biomedical) data

Big (Biomedical) DataPanel discussion

• (Chair) Fiona Nielsen, CEO, DNAdigest and Repositive• Adam Auton, Senior Statistical Geneticist, 23andMe• Mathew Woodwark, Director of Research Bioinformatics,

MedImmune• Eric Little, VP Data Science, Osthus

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Big Biomedical Data – chair introduction

Pistoia Alliance European Conference 2016

• Fiona Nielsen, CEO of DNAdigest and Repositive

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Big Biomedical Data – intro


• High throughput technologies – biology is moving from the lab to the computer

2006 2007 2008 2009 2010 2011 2012 2013 2014 2015

Genomes Sequenced

80+ PB

Sequenced every year

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• Growing interest and growing databanks

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• Genomics, Proteomics, metabolomics, all the omics!

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• Challenges in all dimensions of big data: Volume, Velocity, Variety, Veracity

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Assay Types

Dedicated to…

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Top 5:GEO (1.8M)PMI Cohort Program (1M)Auria Biopankki (1M)EGA (~0.6M)SRA (~0.5M)

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Aboriginals

African Americans

Africans

Australians

Chinese

MalaysIndians

DanishDutch Estonian

Russian

European Ancestry

FinnishIcelandic

JapaneseKorean

Latin Americans

Saudi

Swedish

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International

Interesting site to look at: http://omicsmaps.com/stats

http://omicsmaps.com/stats

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• Challenges in all dimensions of big data: How to collect? How to store? How to analyse?

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• Challenges for international research community: How to work across borders and silos?

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• Additional challenges for biomedical: Data privacy, data governance, patient consent, medical legislation

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• How will the landscape change when genomics moves to the clinic?

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• Is Big Data a promise of Big Findings?

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• Community-led databanks: patient groups, academia, the general public

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• For our panel discussion: • How can Pistoia Alliance members uncover

value from Big Biomedical Data?

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Big (Biomedical) Data panel speakers:


Adam AutonSenior Statistical Geneticist, 23andMe

Mathew WoodwarkDirector of Research Bioinformatics, MedImmune

Eric LittleVP Data Science, Osthus

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Thanks to our panel speakers:


Adam AutonSenior Statistical Geneticist, 23andMe

Mathew WoodwarkDirector of Research Bioinformatics, MedImmune

Eric LittleVP Data Science, Osthus