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© 2004 John Wiley & Sons, Inc.Huffman: PSYCHOLOGY IN ACTION, 7E
Central Nervous System
• The CNS is composed of the brain and spinal cord
• Spinal cord connects the brain with the PNS– Spinal cord is comprised of cell bodies and
axons that carry messages• Afferent: toward the brain (sensory function)• Efferent: away from the brain (motor function)
© 2004 John Wiley & Sons, Inc.Huffman: PSYCHOLOGY IN ACTION, 7E
Peripheral Nervous System
• The Peripheral Nervous System (PNS) includes all nerves outside the brain and spinal cord– Somatic NS carries sensory messages to
brain and motor commands to the muscles– Autonomic NS regulates automatic body
functions (such as heart rate, breathing)• Sympathetic: “Fight or Flight”• Parasympathetic: dominant when relaxed
© 2004 John Wiley & Sons, Inc.Huffman: PSYCHOLOGY IN ACTION, 7E
Neurons
• Neurons are cells that transmit information
• Neurons are composed of:– Dendrites: receive information and pass it
to cell body– Cell Body: summarizes information– Axon: extends from cell body, carries
electrical potential, sends a chemical message to adjacent neurons
© 2004 John Wiley & Sons, Inc.Huffman: PSYCHOLOGY IN ACTION, 7E
Synapse
• The synapse is the junction between an axon terminal and an adjacent dendrite or cell body.
• Neurotransmitter (NT) molecules are released from the axon terminal into the synapse when the action potential arrives at the axon terminal.
© 2011 The McGraw-Hill Companies, Inc.
Neurotransmitters
Neurotransmitters carry information
across the synaptic gap to next neuron.
Acetylcholine• muscle actions, learning, memory• black widow venom ↑ Ach levels • botox (botulin) ↓ Ach levels • Alzheimer’s disease: ↓ Ach levels
GABA • anxiety: ↓ GABA levels
© 2011 The McGraw-Hill Companies, Inc.
Neurotransmitters
Glutamate– excitatory – learning & memory– involved in many psychological disorders
Norepinephrine– stress and mania: ↑ norepinephrine levels– depression: ↓ norepinephrine levels– regulates sleep states in conjunction with ACh
© 2011 The McGraw-Hill Companies, Inc.
Neurotransmitters
Dopamine
– voluntary movement– reward anticipation– stimulant drugs: activate dopamine
receptors– Parkinson’s disease: ↓ dopamine levels– schizophrenia: ↑ dopamine levels
© 2011 The McGraw-Hill Companies, Inc.
Neurotransmitters
Serotonin– regulation of sleep, mood, attention,
learning– depression: ↓ serotonin levels– prozac: ↑ serotonin levels
Endorphins– natural opiates– mediate feelings of pleasure and pain
© 2004 John Wiley & Sons, Inc.Huffman: PSYCHOLOGY IN ACTION, 7E
Resting Potential
Sodium ions are concentrated on the outside of the axon membrane.
Potassium ions are concentrated on the inside of the axon membrane.
Ion channels are closed.
The inside of the axon membrane is more negative that is the outside.
© 2011 The McGraw-Hill Companies, Inc.
Neurotransmitters
Oxytocin– both a hormone and a neurotransmitter– related to onset of lactation in new mothers– related to attachment/emotional bonds
Note: Drugs can interfere with neurotransmitters
– mimics or enhances NT effects– blocks effects of NT
© 2004 John Wiley & Sons, Inc.Huffman: PSYCHOLOGY IN ACTION, 7E
Action Potential
• Action potential occurs when the membrane potential rapidly shifts from -70 to +40 mV– Ion channels open in the membrane, allowing
sodium ions to enter the axon– Sodium entry shifts the membrane potential
toward a positive value– Potential is restored when other channels open,
allowing potassium ions to exit the axon
© 2004 John Wiley & Sons, Inc.Huffman: PSYCHOLOGY IN ACTION, 7E
Action Potential Details
• Action potentials vary in frequency (a few pulses per second to a max of 1000 pulses per second)
• APs have a refractory period (about 1 msec)
• AP is “all or none” in nature
© 2004 John Wiley & Sons, Inc.Huffman: PSYCHOLOGY IN ACTION, 7E
Myelin
• Myelin is a fatty, waxy substance coating the axon of some neurons.
• Functions:– Speeds neurotransmission– Insulates neurons from each other– Makes neurotransmission more efficient
© 2004 John Wiley & Sons, Inc.Huffman: PSYCHOLOGY IN ACTION, 7E
Brain imaging technologies
• Positron Emission Tomography (PET)• Makes use of radioactive tracer to measure
cerebral blood flow.
© 2004 John Wiley & Sons, Inc.Huffman: PSYCHOLOGY IN ACTION, 7E
Brain imaging technologies
• Functional Magnetic Resonance Imaging (fMRI)
• Uses electromagnets to measure oxygen levels in brain.
© 2004 John Wiley & Sons, Inc.Huffman: PSYCHOLOGY IN ACTION, 7E
Psychoactive Drugs
• Psychoactive drugs affect the nervous system to alter mood, emotion, and thought
• Psychoactive drugs act by:– Increasing or decreasing release
of neurotransmitters – Stimulating or blocking receptor
sites
© 2004 John Wiley & Sons, Inc.Huffman: PSYCHOLOGY IN ACTION, 7E
Psychoactive Drugs
• Agonists enhance neurotransmitter function
• Antagonists block neurotransmitter function
© 2004 John Wiley & Sons, Inc.Huffman: PSYCHOLOGY IN ACTION, 7E
The Endocrine System
• Hormones are secreted into the blood by the endocrine system
• Hypothalamus controls hormone release
© 2004 John Wiley & Sons, Inc.Huffman: PSYCHOLOGY IN ACTION, 7E
The Endocrine System
Functions of the endocrine system:
1. Maintain homeostasis
2. Regulate reproductive system
© 2004 John Wiley & Sons, Inc.Huffman: PSYCHOLOGY IN ACTION, 7E
Brainstem
• Brainstem is a primitive portion of brain– Pons: involved in respiration, sleep
regulation, dreaming– Medulla: involved in life support functions
such as respiration and heart rate– Reticular activating system is an arousal
system within the brainstem
© 2004 John Wiley & Sons, Inc.Huffman: PSYCHOLOGY IN ACTION, 7E
Subcortical Brain Areas
• Corpus callosum: band of axons that interconnects the hemispheres
• Thalamus: sensory relay area
• Limbic system: involved in emotionality
• Hypothalamus: feeding, fleeing, mating, fighting, homeostasis
• Cerebellum: involved in motor control
© 2004 John Wiley & Sons, Inc.Huffman: PSYCHOLOGY IN ACTION, 7E
Limbic System: Seat of Motivation, Emotions
© 2004 John Wiley & Sons, Inc.Huffman: PSYCHOLOGY IN ACTION, 7E
Cerebral Cortex• Cortex refers to the outer covering of the brain
– Consists of left and right hemispheres
– Cortex is divided into lobes• Frontal: Self-awareness, planning, voluntary movement,
emotional control, speech, working memory• Parietal: Body sensations• Occipital: Vision• Temporal: Hearing, language comprehension
– Localization of function: do discrete circuits carry out different functions?
© 2004 John Wiley & Sons, Inc.Huffman: PSYCHOLOGY IN ACTION, 7E
Summary of Hemispheric Specializations
© 2004 John Wiley & Sons, Inc.Huffman: PSYCHOLOGY IN ACTION, 7E
Split-Brain Research
• When a split-brain patient is asked to stare straight ahead while a photo of a fork is flashed to his left visual field, he cannot name it.
© 2004 John Wiley & Sons, Inc.Huffman: PSYCHOLOGY IN ACTION, 7E
Behavioral Genetics• Behavioral genetics examines the influence of
genes (versus environment) on behavior• Research strategies:
– Twin studies: compare the concordance (agreement) rates between identical and fraternal twins
– Adoption studies: compare the similarity between adopted children and their biological/adopted parents
– Mutations: examine behaviors in genetically abnormal subjects or in animals in which a specific gene has been “knocked out”
© 2004 John Wiley & Sons, Inc.Huffman: PSYCHOLOGY IN ACTION, 7E
Evolutionary Psychology
• Darwin argued that natural forces select traits that are adaptive for survival– Natural selection: certain traits are passed on
because these traits gave an advantage for survival
• Organisms with these traits are able to reproduce and pass on the trait to their offspring
– Genetic mutations can be beneficial or disastrous
• Evolutionary psychology examines how evolutionary processes impact behavior
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