11 Biology 1-16-08 Circulatory System

7/31/2019 11 Biology 1-16-08 Circulatory System

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You Gotta Have HeartThe Circulatory System

Explore

How does exercise affect heart rate?

Circulatory System Relay Color Your Heart

Hemo the Magnificent

Scene 6 – The Capillaries

Circulatory System Consists of…

Blood Vessels

Circulatory SystemBLOOD VESSELS

Two Pathways

Pulmonary Circulation

– Carries blood to lungs and back

Systemic Circulation

– Carries blood to body and back

Capillaries of head and arms

Capillaries of abdominalorgans and legs

Inferior vena cava

Pulmonary vein

Capillaries of rightlung

Superior vena

cava Aorta

Pulmonary artery

Capillaries of leftlung

Your Blood Vessels:Pathway of Circulation

3 types of vessels

– Arteries

– Capillaries

– Veins

Artery vs. Vein

Arteries: carries blood Away from heart

– Large

– Thick-walled, Muscular

– Elastic – Oxygenated blood

Exception Pulmonary Artery

– Carried under great pressure – Steady pulsating

Arterioles: smaller vessels, enter tissue

Capillaries

– Smallest vessel

– Microscopic

– Walls one cell thick

– Nutrients and gases diffuse here

Veins: Carries blood to heart

– Carries blood that containswaste and CO2

Exception pulmonary vein

– Blood not under muchpressure

– Valves to prevent much

gravity pull

Venules: larger than capillaries

Varicose VeinsDamaged Valves in Veins

What is Blood?

Blood Simulation

Whole Blood Sample

Red bloodcells

White bloodcells

Platelets

Plasma

Sample Placed in Centrifuge Blood Sample ThatHas Been Centrifuged

Whole Blood Sample

Red bloodcells

White bloodcells

Platelets

Plasma

Whole Blood Sample

Red bloodcells

White bloodcells

Platelets

Plasma

Parts of the Blood

Your Blood: Fluid Transport

a Tissue

50% water

4% dissolvedsubstances

Liquid Portion Carries

Blood cells

– Erythrocytes (RBC - red bloodcells)

– Leucocytes (WBC - white bloodcells)

Platelets (non cellular particles)

Proteins

– Enzymes

– Hormones – Endocrine System

Nutrients - Digestive System

Gases - Respiratory System

Inorganic salts

Carbon Dioxide in the Blood

Hemoglobin carries CO2 also

CO2 is a waste product of cellular work

70% of CO2 combines withwater

The rest travels to the lungs

What does blood contain?

50% Water

45% Erythrocytes 4% Plasma with Substances

1% Leukocytes + Platelets

Erythrocytes (RBC) Transporters of

– Oxygen – Carbon Dioxide

RBC – Lack a nucleus – Contain hemoglobin

– Disk-shaped RBC are produced in red bone

marrow of – ribs, – humerus,

– femur, – sternum, and other long bones

Lives for 120 days Old RBC are destroyed in liver

and spleen

Leukocytes (WBC)

WBC fight infection – Attack foreign

substances

Less abundant

Large cells

Some live for

months – Most just a few days

Several types

ALL contain nuclei

Platelets

PLATELETS are for CLOTTING blood

Cell fragments

Produced in bone marrow

Short life span (1 week)

Fibrin (sticky network of proteinfibers)

– Form a web trapping blood cells

Circulatory SystemHEART

Your Heart: The Vital Pump

At REST, the heartpumps about 5

QUARTS of blood aminute.

During EXTREME

EXERTION (exercise)it can pump 40 quartsa minute.

Heart:Structure and Function

Keeps blood moving

Large organcomposed of

– cardiac muscle,

– rich in mitochondria

– Enclosed by a sac PERICARDIUM

The Structures of the Heart

Right Ventricle

Right Atrium

Left Atrium

Inferior Vena CavaVein that brings oxygen-poorblood from the lower part ofthe body to the right atrium

Tricuspid ValvePrevents blood from flowing

back into the right atrium after ithas entered the right ventricle

Pulmonary ValvePrevents blood from flowingback into the right ventricleafter it has entered thepulmonary artery

Pulmonary VeinsBring oxygen-rich blood from eachof the lungs to the left atrium

Superior Vena CavaLarge vein that brings oxygen-poor blood from theupper part of the body to the right atrium

AortaBrings oxygen-rich blood from the leftventricle to the rest of the body

Pulmonary ArteriesBring oxygen-poor bloodto the lungs

Aortic ValvePrevents blood from flowingback into the left ventricleafter it has entered the aorta

Mitral ValvePrevents blood from flowing backinto the left atrium after it has

entered the left ventricle

Left Ventricle

Septum

Blood Flow Through the Heart

©COPY 1997 HeartPoint

Bloods Path Through the Heart

Both Atria fill at same time

– Rt atrium receives oxygen POOR blood frombody from vena cava

– Left atrium receives oxygen RICH blood from

lungs through four pulmonary veins

After filled with blood atria contract,

pushing blood into ventricle

Both ventricles contract

Right ventricle contracts and pushes

oxygen-poor blood toward lungs, against gravity,

through pulmonary arteries

Left ventricle contracts and forces oxygen

rich blood out of heart through

aorta (largest vessel)

Bloods Path Through the Heart(cont)

Heartbeat Regulation

Force of blood from left ventricle into arteries(pulse)

Pacemaker (SA Node), group of cells at top of right atrium

Electrical impulse, signals BOTH atria to contract

Triggers 2nd set of cells (AV Node)-base of theright atrium to send message to ventricles, theycontract

EkG – record of electrical changes in the heart

Sinoatrial(SA) node

Atrioventricular(AV) node

Conductingfibers

Contraction of Atria Contraction of Ventricles

The Sinoatrial Node

Blood Pressure

Blood against the blood vessel’s walls

– The systolic pressure refers to

the pressure recorded while the ventricles pumpthe blood.

– The diastolic pressure refers to

the pressure recorded as the ventricles fill with

blood.

A normal blood pressure is 120/80

DISORDERS

ATHEROSCLEROSIS

– Fatty deposits called plaque

– Builds up in walls of arteries

– Obstructs flow

– Also a risk if clot breaks free and blocks flow

elsewhere

Disorders (cont)

Hypertension

– High blood pressure

– Hearts works harder than necessary

– Increases risk of heart attack or stroke

Disorders (cont)

Heart Attack

– Atherosclerosis in coronary artery

– Heart muscle begins to die

Symptoms

– Nausea – Shortness of breath

– Severe chest pain

IMMEDIATE MEDICAL ATTENTION NECESSARY

Disorders (cont)

Stroke

– Blood clot gets stuck in blood vessels leading

to brain

– Brain cells die due to lack of oxygen

Or blood vessel burst

– Can lead to paralysis,

loss of ability to speak

C t PREVENTION

Current PREVENTIONRecommendations

Regular exercise

Weight control

Well balanced diet

Do not smoke

Diet low in saturated

Elaboration

Blood Typing: To Clump or Not to Clump?

Blood Types

Massive loss of blood requires a transfusion

Four Types – A

– AB – O

Inherited from your parents

Blood Types

What happens hen o mi blood

What happens when you mix bloodtypes?

Plasma contains proteins thatcorrespond to the shape of the

different antigens If you mix one type with the

wrong one, you get CLUMPING

Type O is the universal donor

Type AB is the universal acceptor

What Makes Our Blood Type?

Blood Transfusions

Blood Typeof Donor

Blood Type of Recipient

A B AB O

Unsuccessful transfusion Successful transfusion

Blood Transfusions

Rh Factor

Rhesus factor (Rh), also inherited

– Rh+ (have antigen)

– Rh- (NO antigen)

Can cause complications in pregnancies

– mother Rh- 1st baby Rh+ : blood mixes withmother; mother’s body makes anti-Rh+

antibodies – 2nd Rh + body attacks baby

– Now have medicine to prevent antibody

11 Biology 1-16-08 Circulatory System

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