1980198219841986 1988 199019921994199619982000200220042006 Number of Tuberculosis Cases: California,...

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2,500

3,000

3,500

4,000

4,500

5,000

5,500

6,000

Year1980 1982 1984 1986 1988 1990 1992 1994 1996 1998 2000 2002 2004 2006

Number of Tuberculosis Cases: California, 1930-2006

Nu

mb

er o

f T

ub

ercu

losi

s C

ases

2,000

4,000

6,000

8,000

10,000

12,000

1930 1940 1950 1960 1970 1980

Number of Tuberculosis Cases and Case Rates: California, 1997-2006

0

1,000

2,000

3,000

4,000

5,000

1997 1998 1999 2000 2001 2002 2003 2004 2005 2006

Year

0

5

10

15

20

Nu

mb

er

of

Ca

ses

Ca

se

Ra

te p

er

100

,00

0

Number of CasesCase Rate per 100,000 Population

Tuberculosis Cases by Race/Ethnicity: California, 2006

Asian/Pacific Islander1,223 (44.0%)

Hispanic1,068 (38.4%)

Unknown4 (0.1%)Black

208 (7.5%)

American Indian/Alaska Native

9 (0.3%)

White267 (9.6%)

Tuberculosis Case Rates by Race/Ethnicity: California, 1997-2006

05

10

1520253035

404550

1997 1998 1999 2000 2001 2002 2003 2004 2005 2006

Year

Cas

es p

er 1

00,0

00

Asian/Pacific Islander

Black

Hispanic

American Indian/Alaska Native

White

Tuberculosis Cases in Foreign-born and U.S.-born Persons: California, 1997-2006

0

500

1,000

1,500

2,000

2,500

3,000

1997 1998 1999 2000 2001 2002 2003 2004 2005 2006

40

50

60

70

80

U.S.-born Foreign-born Percent Foreign-born

Nu

mb

er o

f C

ases

Per

cen

t o

f C

ases

Tuberculosis Cases by Country of Origin: California, 2006

U.S.-born630 (22.7%)

Foreign-born2,136 (76.9%)

Unknown13 (0.5%)

Philippines427 (20.0%)

Mexico670 (31.4%)

All Others770 (36.0%)

Vietnam269 (12.6%)

67

Tuberculosis Cases in Persons 0-4 Years of Age: California, 1997-2006

0

50

100

150

200

250

1997 1998 1999 2000 2001 2002 2003 2004 2005 2006

Year

0

1

2

3

4

5

Nu

mb

er o

f C

ases

Per

cen

t o

f C

ases

Number of Cases Percent of Cases

Tuberculosis Cases by Verification Criteria: California, 2006

Provider Diagnosis199 (7.2%)

Positive Culture2,241 (80.6%)

Clinical Case326 (11.7%)

Positive Smear13 (0.5%)

Deaths in Persons with Tuberculosis: California, 1996-2004

0

100

200

300

400

500

1996 1997 1998 1999 2000 2001 2002 2003 2004

Year

0

2

4

6

8

10

12

Per

cen

t o

f C

ases

Nu

mb

er o

f D

eath

s

Dead at Diagnosis

Died During Treatment Died Before Starting Treatment

Percent Dying with Tuberculosis

Tuberculosis Cases by AIDS Diagnosis*: California, 1995-2004

0

100

200

300

400

500

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004

Year

0

2

4

6

8

10

Nu

mb

er o

f C

ases

wit

h A

IDS

Per

cen

t o

f C

ases

wit

h A

I DS

* Match found in AIDS Case Registry, California Office of AIDS.

Number of Tuberculosis Cases with AIDSPercent of Tuberculosis Cases with AIDS

AIDS-associated Tuberculosis* by Race/Ethnicity: California, 1995-2004

0

25

50

75

100

125

150

175

200

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004

Year

Nu

mb

er o

f C

ases

wit

h A

IDS Hispanic

Black

White

Asian/Pacific IslanderAmerican Indian/Alaska Native

* Match found in AIDS Case Registry, California Office of AIDS.

0

10

20

30

40

50

60

70

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004

Initial Susceptibility Test Final Susceptibility Test

Tuberculosis Cases with Multidrug-resistance (MDR) on Initial or Final Drug Susceptibility

Testing*: California, 1995-2004N

um

ber

of

MD

R T

ub

ercu

losi

s C

ases

*Cases with resistance to at least isoniazid and rifampin reported on the Initial Drug Susceptibility Report (Follow-up 1) or on the Case Completion Report (Follow-up 2).

58

48 47

3942

3539

43

3440

Tuberculosis Cases with Initial Multidrug-resistance (MDR)*: California, 2002-2006

*Cases with initial drug resistance to at least isoniazid and rifampin.

Long Beach

Pasadena

Berkeley

San Francisco

25 Cases

15-24 Cases

5-14 Cases

1-4 Cases

None

Initial MDR Cases:2002-2006

Tuberculosis Cases1 by Outcome of Therapy in Reporting Jurisdiction: California, 2004

Completed Therapy 12 Months2,075 (71.5%)

Completed Therapy >12 Months313 (10.8%)

Moved2

234 (8.1%)

Died183 (6.3%)

Lost3

49 (1.7%) Refused10 (0.3%)

Other18 (0.6%)

1 Patient alive at diagnosis and started on an initial drug regimen of one or more drugs.2 Patient moved to another jurisdiction with a known forwarding address before treatment was completed.3 Patient could not be located prior to the completion of treatment.

No Info22 (0.8%)

Completed Therapy 12 Months18 (20.2%)

Completed Therapy >12 Months38 (42.7%)

Moved3

13 (14.6%)

Died10 (11.2%)

Lost4

4 (4.5%)

NoInformation 5 (5.6%)

1Treatment in the jurisdiction reporting the case. 2Includes cases with rifampin resistant disease, cases with meningeal disease, and cases less than 15 years of age with disseminated tuberculosis disease.

3 Patient moved to another jurisdiction with a known forwarding address before treatment was completed.4 Patient could not be located prior to the completion of treatment.

Refused1 (1.1%)

Outcome in Tuberculosis Cases1 for Whom Greater than One Year of Treatment

was Indicated2: California, 2004

Completed Therapy 12 Months18 (20.2%)

Completed Therapy >12 Months38 (42.7%)

Moved3

13 (14.6%)

Died10 (11.2%)

Lost4

4 (4.5%)

NoInformation 5 (5.6%)

1Treatment in the jurisdiction reporting the case.2Includes cases with rifampin resistant disease, cases with meningeal disease, and cases less than 15 years of age with disseminated tuberculosis disease.

3 Patient moved to another jurisdiction with a known forwarding address before treatment was completed.4 Patient could not be located prior to the completion of treatment.

Refused1 (1.1%)

Outcome in Tuberculosis Cases1 for Whom Greater than One Year of Treatment

was Indicated2: California, 2004

Completion of Tuberculosis Therapy: California,1995-2004

0

20

40

60

80

100

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004Per

cen

t o

f C

ases

Co

mp

leti

ng

Th

erap

y

CompletedCompleted in 1 year or less

Note: Excludes cases with rifampin resistant disease, cases with meningeal disease, cases less than 15 years of age with disseminated tuberculosis disease, and those that died during treatment.

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