Alternative Medicine Joins the Mainstream · Deepak Chopra Deepak Chopra. Alternative Medicine...

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Dean Ornish

Dean Ornish

Mike Milken

Mike Milken

William Nelson

William Nelson

Deepak Chopra

Deepak Chopra

Alternative Medicine Joins the MainstreamAlternative Medicine Joins the Mainstream

Consciousness Creates RealityConsciousness Creates RealityCo-create and reflect each other, interdependently co-arise, are a tangled hierarchy.

They are synchronistically arising emergent properties that co-emerge

depending on the level of vibration of individual and collective consciousness.

Co-create and reflect each other, interdependently co-arise, are a tangled hierarchy.

They are synchronistically arising emergent properties that co-emergedepending on the level of vibration of individual and collective consciousness.

5 Breakthroughs for the Body5 Breakthroughs for the Body

Your body is a process, not a structure. Your body is a process, not a structure.

Your body is an energy field.Your body is an energy field.

Your can turn your genes on and off. Your can turn your genes on and off.

You can change your relationship with time.You can change your relationship with time.

Awareness is the key to transformation and Awareness is the key to transformation and

reinventing the body. reinventing the body.

Resurrecting the SoulResurrecting the Soul

Your life is a flow of effortless spontaneity. Your life is a flow of effortless spontaneity.

Love is the soulLove is the soul’’s only motivation s only motivation

You have unlimited You have unlimited imagination imagination and creativity and creativity

You invite Grace in your life You invite Grace in your life

You choose evolution over entropy.You choose evolution over entropy.

Our “health care” system is really a disease care system.

Our “health care” system is really a disease care system.

$2.1 trillion spent last year on medical care = 16.5% of GDP

95% spent to treat disease after it had already occurred

$2.1 trillion spent last year on medical care = 16.5% of GDP

95% spent to treat disease after it had already occurred

If we want to make health care available to the 48 million

Americans who don’t have it, we need to address the underlying

causes

of disease.

If we want to make health care available to the 48 million

Americans who don’t have it, we need to address the underlying

causes

of disease.

Your body often has a remarkable capacity to begin healing itself if you give it a

chance to do so —

and quickly.

Your body often has a remarkable capacity to begin healing itself if you give it a

chance to do so —

and quickly.

Cardiovascular diseases kill more people worldwide each year

than all other illnesses combined.

Cardiovascular diseases kill more people worldwide each year

than all other illnesses combined.

In a study of over 30,000 patients, heart disease was completely

preventable

for almost 95%

of people

just by changing diet and lifestyle.

Yusuf S et al. Lancet. 2004 Sep 11;364(9438):937-52.

In a study of over 30,000 patients, heart disease was completely

preventable

for almost 95%

of people

just by changing diet and lifestyle.

Yusuf S et al. Lancet. 2004 Sep 11;364(9438):937-52.

In 2006, 1.3 million

angioplasties were performed at a cost of more

than $60 billion.

In 2006, 1.3 million

angioplasties were performed at a cost of more

than $60 billion.

COURAGE TRIAL

“Angioplasty did not reduce the risk of death, heart attack, or other major cardiovascular

events.

--Boden

WE et al. N Engl J Med 2007;356:1-14.

COURAGE TRIAL

“Angioplasty did not reduce the risk of death, heart attack, or other major cardiovascular

events.

“--Boden

WE et al. N Engl J Med 2007;356:1-14.

In 2006, 448,000 coronary bypass operations were performed at a cost of more than $44 billion.

In 2006, 448,000 coronary bypass operations were performed at a cost of more than $44 billion.

Coronary bypass surgery prolongs life in only 2-3% of those who

receive it.

.

--Caracciolo

EA et al.�Circulation. 1995;91(9):2325-34.

Coronary bypass surgery prolongs life in only 2-3% of those who

receive it..

--Caracciolo

EA et al.�Circulation. 1995;91(9):2325-34.

Dangerous, invasive, expensive,

and ineffective

Dangerous, invasive, expensive,

and ineffective

Coronary heart disease is not only preventable, it is usually

reversible

by changing diet

and lifestyle.

Coronary heart disease is not only preventable, it is usually

reversible

by changing diet

and lifestyle.

Optimal Lifestyle ProgramOptimal Lifestyle Program

•Nutrition•Stress management•Moderate exercise•Psychosocial support

The primary determinant of improvement

was the degree of lifestyle change.

The primary determinant of improvement

was the degree of lifestyle change.

Scaleability

& Cost EffectivenessScaleability

& Cost Effectiveness

•Three demonstration projects

•More than 3,000 patients

•Greater changes in diet and lifestyle, larger improvements in risk factors and quality of life, and bigger cost reductions than have ever before been reported in an ambulatory group of patients.

•Three demonstration projects

•More than 3,000 patients

•Greater changes in diet and lifestyle, larger improvements in risk factors and quality of life, and bigger cost reductions than have ever before been reported in an ambulatory group of patients.

1. The Multicenter Lifestyle Demonstration Project

1. The Multicenter Lifestyle Demonstration Project

Almost 80% of 333 patients who were eligible for bypass surgery or angioplasty were able to safely avoid it.

Ornish

D. Avoiding revascularization with lifestyle changes: The Multicenter Lifestyle Demonstration Project. American Journal of

Cardiology. 1998;82:72T-76T.

Koertge

J, Weidner G, Elliott-Eller M, et al. Improvement in medical risk factors and quality

of life in women and men with coronary artery disease in the Multicenter Lifestyle Demonstration Project. American Journal of Cardiology. 2003;91:1316-1322.

Almost 80% of 333 patients who were eligible for bypass surgery or angioplasty were able to safely avoid it.

Ornish

D. Avoiding revascularization with lifestyle changes: The Multicenter Lifestyle Demonstration Project. American Journal of

Cardiology. 1998;82:72T-76T.

Koertge

J, Weidner G, Elliott-Eller M, et al. Improvement in medical risk factors and quality

of life in women and men with coronary artery disease in the Multicenter Lifestyle Demonstration Project. American Journal of Cardiology. 2003;91:1316-1322.

Mutual of Omaha calculated saving almost $30,000 per patient in the first

year.

Ornish

D. Avoiding revascularization with lifestyle changes: The Multicenter Lifestyle Demonstration Project. American Journal of Cardiology. 1998;82:72T-76T.

Koertge

J, Weidner G, Elliott-Eller M, et al. Improvement in medical risk factors and quality

of life in women and men with coronary artery disease in the Multicenter Lifestyle Demonstration Project. American Journal of Cardiology. 2003;91:1316-1322.

Mutual of Omaha calculated saving almost $30,000 per patient in the first

year.

Ornish

D. Avoiding revascularization with lifestyle changes: The Multicenter Lifestyle Demonstration Project. American Journal of Cardiology. 1998;82:72T-76T.

Koertge

J, Weidner G, Elliott-Eller M, et al. Improvement in medical risk factors and quality

of life in women and men with coronary artery disease in the Multicenter Lifestyle Demonstration Project. American Journal of Cardiology. 2003;91:1316-1322.

1. The Multicenter Lifestyle Demonstration Project

1. The Multicenter Lifestyle Demonstration Project

2. The Highmark Blue Cross Blue Shield Demonstration Project:

Cost Comparisons After 3 Years

2. The Highmark Blue Cross Blue Shield Demonstration Project:

Cost Comparisons After 3 Years

Experimental Group (CAD) (N=75) Baseline vs. 3 year average

= 8.7% decrease in costs

Matched Cohort Members (CAD) (N=75) Baseline vs. 3 year average = 47.2% increase in costs

Experimental Group (CAD) vs. Matched Cohort (CAD) Members Year by Year

$-

$2,000.00

$4,000.00

$6,000.00

$8,000.00

$10,000.00

Ornish Members (CAD) Matched Cohort Members

Ornish Members (CAD) 5377.56 4627.88 5241.27 4865.17

Matched Cohort Members 5344.32 8586.89 8115.56 6897.78

baseline year 1 year 2 year 3

Medicare is now covering this program for reversing heart disease

Medicare is now covering this program for reversing heart disease

6.74

6.23

5.98

6.36

5.8

6.05

6.3

6.55

6.8

Baseline 12 months

Control(n=41)Experimental(n=43)

Changes in PSA

P= 0.002Ornish

D et al. Journal of Urology. 2005;174:1065

8 %

1 %

-5 %-5 %

-1 %

3 %

7 %

L o w (< 4 8 % ) M e d iu m(4 8 -8 8 % )

H ig h (> 8 8 % )

D e g r e e o f L ife s ty le C h a n g e a n d C h a n g e s in P S A

P = 0 .0 0 1Ornish

D et al. Journal of Urology. 2005;174:1065

Change in Prostate Tumor Growth (LNCaP)

-9%

-70%

-70%

-55%

-40%

-25%

-10%

%FBS

ControlExperimental

t = -6.9, P = .000

Ornish

D et al. Journal of Urology. 2005;174:1065

- 7 .9-3 8 .7

- 7 1 .9

-8 0-6 0-4 0-2 0

0

L o w(< 4 8 % )

M e d iu m(4 8 -8 8 % )

H ig h(> 8 8 % )

D e g r e e o f L ife s ty le C h a n g e a n d In h ib itio n o f L N C a P T u m o r G r o w th

B a s e lin e -1 2 m c h a n g e in L N C A P c e ll g ro w thP = 0 .0 0 0 1Ornish

D et al. Journal of Urology. 2005;174:1065

1 year laterPSA -

4.5 ng/mlBaseline

PSA -

6.4 ng/ml

Changes in MRI spectroscopy

Change your lifestyle, Change your genes

Gene expression in over 500 genes was beneficially

affected.

Gene expression in over 500 genes was beneficially

affected.

Ornish D et al, Proc Nat Acad

Sci

2008; 105: 8369.

Genes controlling tumor formation, oxidative stress, and

inflammation were downregulated.

We found a set of RAS family oncogenes

(RAN, RAB14, RAB8A) to be downregulated.

Downregulation

of Oncogenes

by Lifestyle Changes

Ornish

et al. Proc Nat Acad Sci USA 2008; 105: 8369.

p < 0.05 (two-tailed)

Increase in telomerase activity from baseline to 3 months

Ornish

D et al. Lancet Oncol. 2008; 9: 1048–57.

18201820 19001900 19501950 20042004

26Years

31Years

49Years

66Years

Source: United Nations Development Program

+5+5

+18+18

+17+17+35+35

Worldwide Life Expectancy GrowthWorldwide Life Expectancy Growth

Lifestyle Affects Quality of Life

U.S. vs. Japan

Lifestyle Affects Quality of Life

U.S. vs. Japan

Life ExpectancyLife Expectancy

67.6 9.4

73.6 7.7

Healthy yearsHealthy years Disabled

years

Disabled

years

U.S. Economy

$13.84 trillion

U.S. Economy

$13.84 trillion

Lifestyle Makes a DifferenceLifestyle Makes a Difference

16% = health care spending$2.2 trillion

16% = health care spending$2.2 trillion

Date: September 22, 2008

U.S. Economy

$13.84 trillion

U.S. Economy

$13.84 trillion

70% of health-care spending

about $1.5 trillion –

is spent on lifestyle-related diseases.

70% of health-care spending

about $1.5 trillion –

is spent on lifestyle-related diseases.

Lifestyle Makes a DifferenceLifestyle Makes a Difference

Date: September 22, 2008

Only in AmericaOnly in America

Who told you to smoke?Who told you to smoke?

Hall of Fame baseball playersHall of Fame baseball players

Who told you to smoke?Who told you to smoke?

Ann SheridanAnn Sheridan Barbara StanwyckBarbara StanwyckJoan CrawfordJoan Crawford

Famous actressesFamous actresses

Who told you to smoke?Who told you to smoke?

Your dentist …Your dentist …

Who told you to smoke?Who told you to smoke?

and your doctors…

and your doctors

Who told you to smoke?Who told you to smoke?

Scientific researchers!Scientific researchers!

Soldiers and sailorsSoldiers and sailors

Who told you to smoke?Who told you to smoke?

Who has NOT

been used in cigarette advertisements to get you to smoke?

Who has NOT

been used in cigarette advertisements to get you to smoke?

a.

Babies

b.

Santa Claus

c.

Supreme court justices

d.

U.S. Presidents

a.

Babies

b.

Santa Claus

c.

Supreme court justices

d.

U.S. Presidents

BabiesBabies

U.S. PresidentsU.S. Presidents

Santa Claus!!Santa Claus!!

Who has NOT

been used in cigarette advertisements to get you to smoke?

Who has NOT

been used in cigarette advertisements to get you to smoke?

a.

Babies

b.

Santa Claus

c.

Supreme court justices

d.

U.S. Presidents

a.

Babies

b.

Santa Claus

c.

Supreme court justices

d.

U.S. Presidents

There is a

“staggering

cost for failing

to contain the

containable.”

There is a

“staggering

cost for failing

to contain the

containable.”

Failure to address chronic diseases adequately costs the

U.S. economy more than $1 trillion annually.

Failure to address chronic diseases adequately costs the

U.S. economy more than $1 trillion annually.

Chronic Disease StudyChronic Disease Study

Diabetes

Heart disease

Hypertension

Stroke

Diabetes

Heart disease

Hypertension

Stroke

Cancers

Pulmonary conditions

Mental disorders

Cancers

Pulmonary conditions

Mental disorders

Chronic Disease StudyChronic Disease Study

Obesity Prevalence Among U.S. Adults 1991

Obesity Prevalence Among U.S. Adults 1991 > 15%> 15%

< 15%< 15%

Obesity Prevalence Among U.S. Adults 2001

Obesity Prevalence Among U.S. Adults 2001

> 15%> 15%< 15%< 15%

Obesity Prevalence Among U.S. Adults 2002

Obesity Prevalence Among U.S. Adults 2002

> 15%> 15%< 15%< 15%

Obesity Rates: U.S. vs. WorldObesity Rates: U.S. vs. World

20022005

Source: World Health Organization / Estimated obesity rates for

people aged 15 years and older / 2005

1.5%1.5%

1.9%1.9%

6.6%6.6%

20.4%20.4%

24.2%24.2%

41.8%41.8%

1.8%1.8%

1.6%1.6%

7.8%

20.9%

21.6%

36.5%

JapanJapan

ChinaChina

FranceFrance

GermanyGermany

U.K.U.K.

U.S.U.S. MENWOMENWOMEN

34.3%34.3%24.0%MexicoMexico

39% of U.S. children ages 9-13 take part in organized exercise each week.

39% of U.S. children ages 9-13 take part in organized exercise each week.

29% of U.S. high school students participate in physical education classes.

29% of U.S. high school students participate in physical education classes.

Physical InactivityPhysical Inactivity

Treatment Costs Are a Small Portion of the Economic Costs

Treatment Costs Are a Small Portion of the Economic Costs

CancerCancer

$500$500$400$400$300$300$200$200$100$100

HeartHeartHypertensionHypertension

MentalMentalDiabetesDiabetes

PulmonaryPulmonaryStrokeStroke

Direct Costs

Indirect Costs

Source: Milken Institute 2007

QUIZ:

How much larger is the average soda in the U.S. compared to France ?

QUIZ:

How much larger is the average soda in the U.S. compared to France ?

1.

5%2.

18%3.

33%4.

52%5.

74%

1.

5%2.

18%3.

33%4.

52%5.

74%

U.S. soft drink portions are 52% larger than in France.

U.S. soft drink portions are 52% larger than in France.

Source: University of Miami School of Medicine/Sheah

Rarback, R.D.

Candy bars sold in Philadelphia are 41% larger than those in Paris.

Candy bars sold in Philadelphia are 41% larger than those in Paris.

Source: University of Miami School of Medicine/Sheah

Rarback, R.D.

A carton of yogurt in the U.S. is 82% larger than in France.

A carton of yogurt in the U.S. is 82% larger than in France.

Source: University of Miami School of Medicine/Sheah

Rarback, R.D.

Source: William Nelson, M.D., Johns Hopkins Hospital

Fewer carcinogens are detected if you flip your burgers multiple times.

Fewer carcinogens are detected if you flip your burgers multiple times.

15-20% decrease in the progression of prostate cancer by increasing consumption of fish and cooked-tomato products by two servings per week after diagnosis.

15-20% decrease in the progression of prostate cancer by increasing consumption of fish and cooked-tomato products by two servings per week after diagnosis.

What You Eat MattersWhat You Eat Matters

Source: June Chan, ScD, UCSF