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2000 antibiotics
antibioticsU 1200
39 - 213Cytotoxic α-Bromoacrylic Derivatives of Distamycin AnaloguesModified at the Amidino Moiety. — Among the new tested compounds,derivative (I) is found to be a new potent cytotoxic agent which now undergoesphase I clinical tests. — (COZZI, PAOLO; BERIA, ITALO; CALDARELLI,MARINA; GERONI, CRISTINA; MONGELLI, NICOLA; PENNELLA, GIU-LIA; Bioorg. Med. Chem. Lett. 10 (2000) 11, 1273-1276; Dep. Chem.,Pharmacia & Upjohn SpA, I-20014 Nerviano, Milano, Italy; EN)
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