ChemInform Abstract: Enantioselective Total Synthesis of Fumonisin B2

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1998 other bioactive products

other bioactive productsU 1300

01 - 258Enantioselective Total Synthesis of Fumonisin B2. — The titlecompound (XIV) is a representative member of a class of mycotoxins knownto exhibit a wide range of biological activities. Its first total synthesis isaccomplished in a convergent manner from the fragments (VI), (XII), and thetricarballylic acid segment. The preparation of building blocks (VI) and (XII) isdescribed. — (SHI, Y.; PENG, L. F.; KISHI, Y.; J. Org. Chem. 62 (1997) 17,5666-5667; Dep. Chem. Chem. Biol., Harvard Univ., Cambridge, MA 02138,USA; EN)

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1998 other bioactive products

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