ChemInform Abstract: Selective Hydrogenolysis of Novel Benzyl Carbamate Protecting Groups

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2000 protection, deprotection

protection, deprotectionO 0345

30 - 070Selective Hydrogenolysis of Novel Benzyl Carbamate ProtectingGroups. — A highly selective deprotection of a 2-naphthylmethyl car-bamate group in the presence of a 4-trifluoromethylbenzyl carbamate groupis achieved by careful hydrogenolysis providing an orthogonal method fordeprotection of amines. — (PAPAGEORGIOU, EDWARD A.; GAUNT,MATTHEW J.; YU, JIN-QUAN; SPENCER, JONATHAN B.; Org. Lett. 2(2000) 8, 1049-1051; Univ. Chem. Lab., Cambridge Univ., Cambridge CB21EW, UK; EN)

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