ChemInform Abstract: Simple and Efficient Preparation of Ketones from Morpholine Amides

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1998 ketones

ketones (benzene compounds)Q 0350

13 - 087Simple and Efficient Preparation of Ketones from Morpholine Amides.— Morpholine-derived amides react with organometallic compounds to yieldketones, in some cases with low amounts of tertiary alcohols as side products.The use of chiral amides allows a simple access to chiral ketones with retentionof stereochemistry and without significant racemization. — (MARTIN, R.;ROMEA, P.; TEY, C.; URPI, F.; VILARRASA, J.; Synlett (1997) 12, 1414-1416;Dep. Quim. Org., Fac. Quim., Univ. Barcelona, E-08028 Barcelona, Spain; EN)

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