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©2013 Waters Corporation 1
Empower Instrument Control
Anders Janesten
Informatics & Instrument Sales Specialist, SW/NO
Nordic User Training 2013, Jurmala
©2013 Waters Corporation 2
Topics
Instrument Control Overview
DANI Instruments GC and Headspace
Agilent Infinity LC Control Project
Agilent 7890 GC projects
Agilent 6850 GC projects
Beckman CE project
Agilent Headspace 7697
ACQUITY Driver Pack 4
©2013 Waters Corporation 3
Versatility
In an environment configured for compliance, Empower
Software lets you collect data and control different
instrumentation such as LC, GC, SFC and CE with
advanced detection techniques such as Mass Detection
and Photo Diode Array.
Empower Software extends beyond traditional
chromatography to include integrated applications such
as Dissolution, Method Validation, Integrated Chemical
Structures, Polymer Analysis and Fusion Method
Development Software.
©2013 Waters Corporation 4
Instrument Control – Drivers
Provide a comprehensive, reliable and robust feature set for each instrument we support.
– Waters works closely with its customers to ensure the instruments supported with Empower Software provide the scientist the capabilities to realize the most value from their instrument investment.
Instrument Driver Approach - Open Instrument Portal (OIP) – Similar to the Microsoft Printer driver approach
– Allows creation of software plug-ins to add hardware control capabilities
– Waters uses its own and other instrument vendors resources to create instrument control
– This allows the laboratory to introduce new hardware without changing the base Empower software application.
Instrument Control Software (ICS), Instrument Control Option Pack (ICOP), Driver Pack (DP)
©2013 Waters Corporation 5
Instrument Control – Driver Support
Agilent Instrument Control Framework
(ICF)
– Instrument control written and supported by
the instrument vendor
– Can be used by all CDS systems
– Allows faster integration with third-party
CDS systems
– Requires development of a “dock” for the
“ship”
©2013 Waters Corporation 6
Extended Instrument Control with Empower Software
Benefit to the Customers: One Software solution for all chromatographic systems
– Consistent Documentation
– Reduced Training, Validation, and Support
Available Today
– 15 Vendors with over 345 Instruments
– Instrument Control Available from major LC Vendors including Waters, Agilent, Shimadzu, Hitachi, and Thermo
– Instrument Control Available from major GC Vendors including DANI, Agilent, Shimadzu, and PerkinElmer (Varian)
New instrument control
– DANI GC and Headspace
– Agilent 6850 GC V1.30
– Agilent ICF v2.1/A.01.05
– Thermo Dionex IC
©2013 Waters Corporation 7
Mass Detection Waters SQD & TQD
Data acquisition and
instrument control of Mass
Detectors.
Greater specificity of
analysis.
Easily use MS and MS/MS
in QC and Development
lab environments.
Empower is the first Chromatography Software to offer Tandem MS control and data processing in a network or regulated environment
©2013 Waters Corporation 8
Empower 3 MS Ion Ratios + Acceptance Tolerance
– For defensible compound confirmation
– Area or Height ratio of 10 Channel : 20 Channel (1 – 4) in same injection
– Acceptance tolerance on result as compared to a reference injection
– Failed values are faulted
©2013 Waters Corporation 9
Empower 3 MS Target Masses
Open Access, Run Samples, QuickStart, Alter Sample
Specify up to 5 base monoisotopic masses in sample table
(not processing method)
Possible adducts entered in PM
Obtain Yes/No answer as to
whether the target mass is
present in sample
©2013 Waters Corporation 10
Empower 3 MS Target Masses
Masses specified in Run Samples supersede the one in the
processing method
©2013 Waters Corporation 11
Empower 3 ACQUITY eCord Information
Summary information
– Injection Count
– Date Of First Injection
– Date Of Last Injection
– Sample Count
– Maximum Pressure
– Maximum Temperature
Information updated after each
injection
Requires updated ICS (driver)
Sample Set Information
Date
Sample Set Name
User Name
System Name
Injection Count
Sample Count
Max Pressure
Max Temperature
Sample Set Complete
Injection information –
associated with injections
eCord Name
Serial Number
Injection Count
©2013 Waters Corporation 12
Empower 3 ACQUITY eCord Information
eCord data viewed and managed in
Configuration Manager
– eCord Summary Table
– eCord Sample Sets table
New eCords are added automatically
when data is acquired using a system containing the eCord
Enumerated custom fields called Column Name and Column
Serial Number (for non-ACQUITY systems)
©2013 Waters Corporation 13
Empower 3 WFCIII
Basic WFC III control in Empower 2
Enhancements in Empower 3
– Fraction annotations on chromatogram
– Fraction table
– Fraction tab in Project window
©2013 Waters Corporation 14
Agilent Infinity LC Control Projects
Agilent ICF Support v2.1 Hotfix 1 project using Agilent ICF
version A.01.04 released April 10, 2013 and available
ICF version A.01.05 completed testing March 29, 2013 and
available
Highlights:
– Multi-system
– Multi-detector
– Transparent ICF updates
– Fraction collection
– Sample Pretreatment
– Windows Server 2008 support
– Defect corrections
ICF A.01.05 SP1 in test
Next ICF Support project in discussion
©2013 Waters Corporation 15
Agilent Infinity LC Control
©2013 Waters Corporation 16
Agilent Infinity LC Control
©2013 Waters Corporation 17
Agilent Infinity LC Control
©2013 Waters Corporation 18
Agilent 7890 GC Projects
V2.5
– Released February, 2012
– Minimum: Empower 2 FR3 required
– Advanced Detector support
o Nitrogen Phosphorus Detector (NPD)
o Sulfur Chemiluminescence Detector (SCD)
o Nitrogen Chemiluminescence Detector (NCD)
o Enhanced Flame Photometric Detector (Enhanced FPD)
– Dual-tower support requires Empower changes (Empower 2 SP H
Hotfix 1 or Empower 3 FR1)
Agilent 7890B compatibility
– 7890B is runs as 7890A
– Additional capabilities under discussion
©2013 Waters Corporation 19
Agilent 6850 GC ICS v1.30
Released December, 2012
– Oven ramp/SQT fix
– Support for 7693 injector basic injection capabilities
– Firmware A.06.02
– Series I still requires Equinox card (XP)
Next project, v1.40, is starting
Planned for v1.40:
– Avocent Hub support
– Micro ECD support
– Support for Fast, Slow, Variable injector speed
©2013 Waters Corporation 20
Beckman CE Systems
Driver version 1.1.5 is available for Empower 2 and Empower 3
Supports Beckman P/ACE MDQ, PA-800, and PA-800 plus
Capillary Electrophoresis Systems
Control includes photo diode array and selectable-wavelength
UV/Vis (200, 214, 254 and 280 nm filters included) detector, UV
source optics, temperature-controlled sample storage module
and Laser Induced Fluorescence (LIF) Detector
Beckman CE Control License
– Includes the instrument control software, license, documentation,
and an IEEE-to-Ethernet converter in order to connect the Beckman
CE (IEEE-488) to a computer via Ethernet.
©2013 Waters Corporation 21
Beckman CE Control
Version 1.2.0 under development
– Auto-increment
– Calibrate PDA
– LIF Calibration Correction Factor
– Multi-system (2)
– Localization to J, C, K
– Defect fixes
– Target: October release
©2013 Waters Corporation 22
Agilent HS7697 Headspace Sampler
Project delayed by legal issues, now resolved
Target is TBD.
©2013 Waters Corporation 23
ACQUITY UPLC Driver Pack 4 (V1.6)
DP2
DP2 Supp2
DP3
DP4
DP4
©2013 Waters Corporation 24
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