Getting to Know ClinicalTrials

Getting to Know ClinicalTrials.gov

David Greenebaum

GaIN Fall Membership Meeting

November 7, 2012

ClinicalTrials.gov

Registry of clinical studies Database of results

Maintained by NLM & NIH Information provided & updated by studies’

sponsors/principal investigators

History of ClinicalTrials.gov

Food and Drug Administration Modernization Act of 1997 (FDAMA) Registry: February 2000

Food and Drug Administration Amendments Act of 2007 (FDAAA), Section 801 Results database: September 2008

Number of studies registered

Studies with results posted

Basic search

QuickTime™ and a decompressor

are needed to see this picture.

Advanced search

Other ways to find studies Browse by topic

Conditions, Rare Diseases, Drug Interventions, Dietary Supplements, Sponsor/Collaborators, Locations

Alphabetical or category listing for each

View on a map

Search results

Study record

Study Record: Full Text View

Purpose Eligibility Contacts and location More information

Study Record: Tabular View

Tracking information Descriptive information Recruitment information Administrative information

Study record: results

Participant flow Baseline characteristics Outcome measures and statistical analyses Adverse events Administrative information

Other neat tricks

Search PubMed for study results by NCT number

Download batches of content for analysis Display & save XML data via URL

parameters