View
7
Download
0
Category
Preview:
Citation preview
FarmertoPharma:Commercialisa1onofNaturalProducts
April2016
Innova1veIngredientsfromNaturalSources
NeilJames
Croda
TheCrodaCompany
Ø Crodahasover80yearsofexperienceinconsumercareØ LeadingproducerofnaturalingredientsforhighgrowthmarketsØ Reputa1onforinnova1on,qualityproductsandexcellentservices;
customerfocused,service-drivencultureØ Unrivalledindustry/marketknowledgeandexperienceØ Globalreachwithopera1onsinover30countriesØ TechnicalandmanufacturingcentresineachmajorregionoftheworldØ ResearchanddevelopmentofnewingredientsisattheheartofCrodaØ Innova1onisthespiritthatdrivesusforward
CrodaataGlance
Ø Sales&marke1ngoffices,distribu1oncentres&keyinnova1oncentreslocatedglobally
Ø 18manufacturingsitesgloballyØ Over3600employeesworldwide
Ø GroupturnoverinexcessofGBP1billionØ HQCowickHall,Snaith,UK
Croda’sBusinessAreas
PersonalCare
Includeshaircare,skincareandsuncare
LifeSciences
CropCare
HealthCare
PerformanceTechnologies
PolymerAddi1ves
Lubricants
HomeCare
GeoTechnologies
Coa1ng&Polymers
ANaturalProductsCompany
Ø Croda’sbusinessiscentredaroundsepara1on,concentra1on,purifica1on&deriva1sa1onofnaturalproducts
Ø Wehavecon1nuedtobuildourexper1seinthesetechniquesforover80years
RenewableChemistryatCroda:AFewExamples
LanolinandDeriva1ves
Ø Naturalrawmaterialsource–woolgreasefromwoolscouringØ 25kTperannumavailableforlanolinproduc1onworldwide
Woolgrease
NeutralisedWoolgrease
Lanolin LanolinAlcohols LanolinFabyAcids
IndustrialGrade-Grease
Deriva1ves Deriva1ves Deriva1ves
LanolinandDeriva1ves
FabyAcidAmides
HighErucicRapeSeed
OilExtracted
OilSplitandFrac1onated
ErucicAcid
Hydrogena1on
BehenicAcid
Quaternisa1on
Condi1oningAgents
Amida1on
Erucamide
PolymerAddi1ve
Glycerol
Behenamide, Stearamide, Oleamide
FabyAcids-General
Ø Crodaisalargeoleo-chemicalsproducerØ Thesearepredominantlyderivedfromnaturalrenewableresources
§ Sunfloweroil§ Palmoil§ Coconutoil§ Rapeseedoil
Ø Oilsaresplitandfrac1onatedatvariousmanufacturingsitesaroundtheworld
Ø VariousfabyacidsarerecoveredandusedtoproducealargerangeofCrodaproductsviafurtherprocessingandderiva1sa1on
Ø Productsincludesemulsifiers,emollients,surfactantsetc
ProteinsandDeriva1ves
Potato
ProteinIsolate
Hydrolysis
HighMwhydrolysate Pep1des
Deriva1sedpep1des
Starch
ProteinsandDeriva1ves
Ø Othersourcesofproteinarereadilyavailablee.g.§ Wheat§ Oat§ Soya§ Pea§ Brazilnut§ Cobonseed§ Collagen§ Kera1n§ Silk
Ø Hydrolysedproteinsareusedinhaircareandskincarefortheirmoisturisingandcondi1oningproper1es
Ø Alsousestarchesandcellulosetomakecosme1cingredientse.g.styling
ProteinsandDeriva1ves
Omega-3MarineOils
CrudeMarineOils
Purify/Separate
Concentra1on
Triglycerides
IncromegaDHA500TGSR
IncromegaEPA500TGSR
IncromegaTG3322
EthylEsters
IncromegaDHA700ESR IncromegaE3322
IncromegaE7010SR IncromegaE4010
FabyAcids
IncromegaF3322
Omega-3MarineOils
BiotechnologyØ T
Ø Theuseof(micro)organismstomanufacturevalueaddedproducts
Ø Caninvolveuseofgene1callymodifiedorganismsØ Harnessestheenormouschemicalpoten1alofliving
organismsØ Microbesrepresentthegreatestreservoirofchemical
diversityontheplanet
WhiteBiotechnology
Ø ODAWhite– Askinlighteningac1vemarketedbySederma.– Basedonoleicacid(C18:1)conversiontoω-dioicacid.– Anotherwiseverydifficultchemicalconversion.– Conversioncarriedoutbyyeastbiotransforma1on.
GreenBiotechnology
Ø Anewprocessforgreenefficacy
― Useofundifferen1atedplantcellstosynthesisetargetedphytomolecules
― Unlimitedavailability-norelianceoncropharvestorseasonality
― Sustainableapproachnottakingupvaluablefarmingland
― Nofer1lizer,nopes1cide,nopreserva1ves
― Enhancedyieldsofthephytochemicalsofinterestcomparedtowholeplantsextrac1ons
BlueBiotechnology
Venuceane™Cosme1cskinac1veproducedbyfermenta1on
Marineextremophilemicro-organismfromdeepseahydrothermalventsØ Highpressure(200bars)Ø Hightemperature(about75°C)Ø NolightØ LibleoxygenØ Toxicenvironmentrichinfreeradicals
Survivesbysynthesizinganenzyma1ccocktailwhichalsooffersbeneficialproper1estotheskin
OtherNaturalSources
Ø Botanicalac1ves§ BlueLotusextract§ Wakameextract(JapaneseKelp)
Ø AmazonianOils§ Murumuru§ Babassu§ Andiroba§ Pequi§ Maracuja§ CastanhadoBrazil§ Cupuacu
Future
Ø Crodarecognisesthebusinessriskassociatedwithalongertermrelianceonfossilfuelderivedrawmaterials
Ø Iscommibedtomi1ga1ngthisriskandfurtherdevelopingitsrelianceonrenewableresources
Ø Recognisesimportanceofsustainabledevelopmentandenvironmentalimprovement
Ø DedicatedtoBio-innova1onØ Greenchemistrywillbeamajorcontributortofutureprocessandproduct
innova1onØ Biotechnology(white,greenandblue)willbecomeamoreimportanttoolfor
developingthenextgenera1onofinnova1veproductsØ Iscommibedtoreducingenergyrequirementsandmovingtorenewable
energies
Recommended