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Honors 391 B, cross-listed with Global Health 490 BHIV AND AIDS: Issues and Challenges
T TH 2:30-4:20 South Campus Center Room 308
Course Instructors:
Danuta (Danka) Kasprzyk, PhD and Daniel E. Montaño, PhDCourse Lectures: April 2 – June 7, 2013 Finals Week: June 10-14, 2013
Contact Info:email: kasprzyk@battelle.org Phone: 206-528-3106 (Danka)
montano@battelle.org Phone: 206-528-3105 (Dan) Course text: AIDS: Science and Society. 7th (SEVENTH) edition, Fan, Conner, Villarreal.
Available at the University bookstore, or on-line (cheaper), or electronically. Please make sure you get the SEVENTH edition.
Chapter summaries, review questions (for Fan, et al., 6th edition) can be accessed at: http://biology.jbpub.com/fan/aids/6e/summaries.aspx. Seventh edition summaries will also be posted at some point (http://biology.jbpub.com/fan/aids/7e ).
Course Description: 5 credits / graded
As part of course requirements, students will present a current event based on each day’s readings or lectures, to be turned in twice weekly by midnight the day before each class period. Link to current event story can be emailed to professors, or turned in as a hard or scanned copy each class period.
Students will be required to write a 15 page research paper. Students will choose a developing country and describe an in-country plan to hit the US Obama Administration goal of ZERO HIV infections (an AIDS-free generation) in their chosen country. Students will describe the in-country AIDS epidemic in terms of its epidemiology (disease transmission and spread), including risk behaviors, and access to treatment. Students will then describe how to reach a goal of zero transmissions within the country by the end of this decade (2019). Students will make evidence-based recommendations targeting the AIDS epidemic for their chosen country and describe whether or how these recommendations will serve to achieve zero HIV transmissions. Papers will be due last week of class (week of June 7, 2013).
For Honors students: Students are encouraged to archive items from this course in their Honors learning portfolios. Readings, lecture notes, and your paper, are examples of items that might assist with reflection on experiential learning and ways of thinking within and across disciplines. The Honors electronic learning portfolios span students’ undergraduate years and are best used as an ongoing, dynamic forum for the integration of knowledge. In addition to archiving items, students are also asked to take a few minutes to write-up a paragraph or two describing the
significance of the archived items and how what they learned in the course contributed to their larger experiences, goals, and thoughts about education and learning.
An optional discussion group to discuss issues in more depth will be held after class on Thursdays.
The course grade is based on the weighting of the paper at 90%, 5% for current events, and 5% for attendance.
At the end of this course, students will be able to:1. Summarize the history of the AIDS epidemic2. Explain how the human-immunodeficiency virus enters the body and attacks the immune
system3. Describe clinical symptoms and manifestations of HIV and AIDS, outline disease stages
and describe disease progression, including acquisition of opportunistic illnesses 4. Compare the treatment policies and options for HIV and AIDS disease between
developed and developing countries5. Summarize issues related to effective treatment of HIV in both developed and developing
countries6. Describe the factors associated with differing nations’ patterns of HIV spread7. Discuss transmission patterns in relation to risk behaviors, describing sexual, drug and
maternal-child transmission of HIV8. Recognize the differing patterns in the national and international spread of HIV and
AIDS and explain how risk behaviors and risk factors vary around the world9. Distinguish the differential risk patterns of the spread of HIV in different countries
around the world, and describe how these patterns create different AIDS epidemics10. Identify how biological and behavioral co-factors, including other sexually transmitted
diseases, play a role in the world-wide spread of HIV11. Discuss effective medical/clinical, vaccine and behavioral HIV prevention strategies12. Summarize the psycho-social, medical, and economic impact of HIV or AIDS on
individuals, families, communities and nations13. Delineate how a chosen country can hit the WHO UNAIDS goal of an “AIDS-free
generation”14. Respond to individuals with HIV who present in class as a panel
COURSE SCHEDULEDate Week Lecture Topic Reading AssignmentsApril 2 1 1 HIV/AIDS:
Overview and origins
Chapter 1Supplemental optional readings:6/2/2006 MMWR dedicated to commemorate 25 years of HIV in the US:http://www.cdc.gov/mmwr/PDF/wk/mm5521.pdf http://aids.gov/thirty-years-of-aids/
April 4 2 HIV/AIDS: Immune system, Virology and Transmission
Chapters 3 and 4
April 9 2 3 Epidemiology of HIV/AIDS: US
Hanne ThiedeChapter 6Supplemental optional readings:CDC Division of HIV/AIDS Prevention. http://www.cdc.gov/hiv/default.htmhttp://www.cdc.gov/mmwr/preview/mmwrhtml/ss5506a1.htm?s_cid=ss5506a1_eState-based HIV/AIDS statisticshttp://www.statehealthfacts.org/Seattle KC: HIV/AIDS Data and Reports: http://www.kingcounty.gov/healthservices/health/communicable/hiv/epi.aspx
April 11
4 Epidemiology of HIV/AIDS: International
Chapter 6Supplemental optional readings:UNAIDS/WHO. AIDS Epidemic Update. December 2010.
Joint Programme on HIV/AIDS, World Health Organization
http://www.unaids.org/EN/about+unaids/index.asphttp://www.unaids.org/globalreport/documents/
20101123_GlobalReport_full_en.pdf http://www.unaids.org/en/resources/epidemiology.asphttp://www.unaids.org/globalreport/AIDSinfo.htm
April 16
6 HIV/AIDS: Disease stages and progression, Clinical manifestations
Sharon Martens Chapter 5
April 18
4 7 Treatment: developing countries
Steve Gloyd
April 23
8 Treatment: developed countries
Bob WoodChapter 5
April 24 Final choice of Country for paper approved by course instructorApril
25 5 9 Sexuality lecture:
culture and sex, sexual practices (oral, anal, vaginal)
Chapter 8 for behavior
Date Week Lecture Topic Reading AssignmentsApril 30 6 11 Behavioral
Prevention: Individual and community models (national and international)
Chapter 9
May 2 15 Sexually Transmitted Diseases
Hunter Handsfield
May 7 10 Transmission patterns: behavioral risk patterns and correlates Sexual networks
Chapter 7Deven Hamilton
May 9 3 5 Maternal-Child transmission
Thor Wagner
May 14 12 Biomedical Prevention: Individual and community prevention models (national and international)
Chapter 9
May 16 7 13 Vaccines Ann Duerrhttp://www.cdc.gov/hiv/vaccine.htmhttp://www.iavi.org/http://www.who.int/vaccine_research/diseases/hiv/en/
May 21 9 14 Zichire: HIV/AIDS research in Zimbabwe
Behavioral prevention liveDanka Kasprzyk “CPOL HIV/STD Prevention Study results”
May 23 8 16 Zichire: HIV/AIDS research in Zimbabwe
Biomedical prevention liveDan Montaño “Circumcision Acceptability Study”
May 28 17 Impact: individual Chapter 10Stigma, mental health, adherence
May 30 18 Impact, family, AIDS orphans
Danka Kasprzyk “Family Health Study”
June 4 10 19 Impact: global Chapter 2; Chapter 10June 6 20 HIV + panel www.poz.com
http://www.thebody.com/index.shtml
Week of June 7
Papers due
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