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Lecture Notes: Lymphatic System
Sec1 Lymphatic System
A) Functions:
B) Organs/Tissues 1) Lymphatic Vessels
2) Lymph Nodes
3) Spleen 4) Thymus
5) Mucosal Associated Lymphatic Tissues
Sec2 Lymphatic Vessels
A) Blood Capillaries 1) Function: a) b) Transport mechanisms:
c) *interstitial fluid
2) Blood flow thru capillary a) Enters at b) Exits at
3) Exchange occurs due to a) Blood Pressure b) Osmotic pressure
4) *Edema
B) Lymphatic Capillaries
1) Struct:
2) Fluid Movements
3) Lymph
C) Lymphatic Vessels
1) Struct:
2) Lymph movement
3) Lymph returned to
Sec3 Lymphatic Organs
A) Lymph Nodes
1) Struct:
2) Funct:
a) Macrophages b) B-cells
B) Spleen 1) Struct:
2) Funct: a) Filter
b) RBC degradation products (1) Iron
(2)
c) Blood Reservoir
3) Hemorrhage
C) Thymus
1) Endocrine Gld:
2) Lymphatic Organ:
D) Mucosal Associated Lymphatic Tissues
1) Tonsils
2) Peyer’s Patches
Sec4 Immune Response
A) *Immune Response:
B) *Antigen:
1) Large Complex Molecules
2) Bacteria: 3) Fungi: 4) Viruses:
C) Body cells have Antigens/
D) Overview
Innate Defense Mechanisms
Adaptive Defense
Mechanisms
1st Line of Defense
2nd Line of Defense 3rd Line of Defense
Sec5 Nonspecific Defense Mechanisms
A) General Characteristics: 1) Target: 2) 3) Time Frame:
B) Include: 1) 1st Line of Defense
2) 2nd Line of Defense
C) 1st Line of Defense: 1) 2) Antimicrobial Secretions
3) Filters:
D) 2nd Line of Defense 1) Cells
2) Proteins
3) 4)
E) Phagocytes: 1) Located 2) Engulf pathogen in vacuole
and fuse with lysosome
3) Examples:
F) Natural Killer Cells 1) Target:
2) Kills with
G) Inflammation
1) Triggered by
2) 4 Hallmark Signs:
3) Histamine
a) Blood vessels b) Activate c) Chemoattractant
4) Purpose:
H) Complement
1) Location 2) Function
I) Interferon 1) Viruses: a) Basic Structure:
b) Takes over host cell’s metabolic machinery
2) Interferon a) Produced by
b) Neighboring cells response
J) Fever 1) Response: 2) Hypothalamus:
a) Normal
b) Reset
3) Purpose:
Sec6 Specific Defense Mechanisms
A) Gen Chars 1) Target 2) Response:
B) Types
C) Lymphocytes
1) B-lymphocytes
a) Produced: b) Mature: c) Receptor:
d) Function:
2) T-lymphocytes
a) Produced: b) Mature: c) Receptor:
d) function
D) Antibody Mediated Immunity
1) Carried out by 2) Activated by
3) Stimulates
a) Plasma Cells
b) Memory Cells
4) Clonal Selection Theory
E) Antibodies: 1) Soluble
a) Produced by b) Identical to c) Antigen binding site
2) Functs: a) Prevents colonization
b) Neutralization
c) Agglutination
3) Immunoglobulins
a) IgG b) IgA c) IgM d) IgE e) IgD
F) Cell-Mediated Immunity
1) Carried out by 2) Activated by
3) Antigen Presenter Cell
4) Results in
5) T-lymphocytes
a)
(1)
(2) Mechanism:
c)
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