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PUTTING THE
PATIENT
AT THE
CENTER OF
HEALTHCARE
RESEARCH
Towards a
more inclusive
model
CONFERENCE OF MONTREAL 2014 2
Information of December 31st 2013
OUR GROUP
SANOFI AT A GLANCE
We are a global healthcare company engaged in the research, development, manufacturing and marketing of healthcare solutions. present
in more than
100 countries
more than
110 000employees
Acomprehensive
offer of pharmaceuticals,
vaccines and innovativetherapeutic solutions
112 Industrial sitesin 41 countries
R&D A major biopharmacy
player
• 45% of revenues generated by biologics
• 80% of development projects are biologics
€33 bn*
In sales in 2013
* €32,951 M
• Multiple Sclerosis• Diabetes• Oncology• Rare Diseases• Cardio-Metabolic Diseases• Immunology• Vaccines• Animal Health
CONFERENCE OF MONTREAL 2014 3
We act as one to discover and develop therapies that prevent, treat and cure disease.
9 projects and vaccines in clinical development*
high potential projects in late stage development*
49
SANOFI R&D
ACCELERATE INNOVATION FOR PATIENTS
Our main areas of research include:
*Information provided as of February 6th, 2014
CONFERENCE OF MONTREAL 2014 4
OUR RESPONSIBILITY
CHANGE THE R&D INNOVATION MODEL
The classic INNOVATION model
Belief that advances in basic sciences can be easily translated to human disease
A linear process from discovery to development to market with little interactions throughout the innovation cycle
Focus on novel (but not necessarily validated) targets in humans
A strategy of “Many Shots on Goal”
A non-linear process that takes into account provider, purchaser and user metrics including pipeline activity, clinical success, regulatory approval, patient access, satisfaction of unmet need and overall value to society
A greater understanding of human disease
Open innovation and partnership
The new INNOVATION model
Raising the batting
average!
CONFERENCE OF MONTREAL 2014 5
OURPRESIDENT OF R&D
PATIENTS ARE THE MISSING LINK
CONFERENCE OF MONTREAL 2014 6
Increasing public awareness & improving clinical trial educationMAKING
CLINICAL TRIALS PATIENT FRIENDLY
SO WHAT ARE WE DOING ABOUT IT?
What do patients know about clinical research? How do they get their facts?How do they know if a study exists?Do they ever hear the results?
Bringing patients within the project teame.g. Diabetes Patient Advisors input into study designs, innovation & outreach strategies
Innovating to ease patient experiencee-informed consente-technology (e.g. telemetry)Point of care technologies (e.g. Dried Blood Spots)
CONFERENCE OF MONTREAL 2014 7
SO WHAT ARE WE DOING ABOUT IT?
BEFORE AND BEYOND CLINICAL TRIALS
Opportunities exists from target to use
Target identificationPath to proof of conceptEffective valueAccess
Partner in Patient Health (PiPH) initiativeEU-NA PiPH CouncilCollaborate | Innovate Challenge
Newly created position of Chief Patient Officer
CONFERENCE OF MONTREAL 2014 8
OUR “RAISON D’ETRE”
ACCELERATE INNOVATION FOR PATIENTS
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