QS404. Massive Transfusion Does Not Predict MOF in Critically Injured Trauma Patients

301ASSOCIATION FOR ACADEMIC SURGERY AND SOCIETY OF UNIVERSITY SURGEONS—ABSTRACTS

RODENT MODEL OF SEVERE BURN TRAUMA. A. M. Al-Mousawi, G. A. Kulp, L. K. Branski, M. G. Jeschke, D. N. Herndon;Shriners Burns Hospital for Children, Galveston, TX

QS403. LYOPHILIZATION CAN INCREASE PLASMA AVAIL-ABILITY WITH A POSITIVE IMPACT ON INFLAMMATORYRESPONSE. A. A. Alexandridis, S. Cho, K. Zink, J. A. Differding,P. J. Muller, A. Karahan, M. A. Schreiber; Oregon Health & ScienceUniversity, Portland, OR

QS404. MASSIVE TRANSFUSION DOES NOT PREDICT MOFIN CRITICALLY INJURED TRAUMA PATIENTS. E. A. Gonza-lez1, K. M. Jastrow, III1, M. F. McGuire2, C. L. Cunningham1, D. W.Mercer1; 1University of Texas Medical School at Houston, Houston,TX; 2University of Texas School of Health Information Sciences atHouston, Houston, TX

QS405. ST2-DEFICIENT MICE EXHIBIT A DEFECT IN BAC-TERIAL PHAGOCYTOSIS AND PHAGOSOME MATURA-TION, AND ARE MORE SUSCEPTIBLE TO POLYMICRO-BIAL SEPSIS. J. M. Buckley, J. H. Wang, H. P. Redmond; CorkUniversity Hospital, Cork, Ireland

QS406. HYPERTONICITY DIFFERENTIALLY REGULATESTNF� STIMULATED CYTOKINE PRODUCTION IN HUMANPULMONARY EPITHELIUM AND MACROPHAGES. W. P.Choi, F. Wright, E. E. Moore, F. Gamboni, A. Banerjee; University ofColorado Health Science Center, Aurora, CO

QS407. INTESTINAL MUCUS PH SHIFTS IN RESPONSE TOSURGICAL INJURY AND ACTIVATES THE VIRULENCE OFINTESTINAL PSEUDOMONAS AERUGINOSA VIA IRON AC-QUISITION. H. Fernandez, O. Zaborina, C. Holbrook, J. Long, A.Zaborin, V. Poroyko, D. Liu, J. Alverdy; University of Chicago, Chi-cago, IL

QS408. APOPTOTIC SIGNALING REGULATES VASCULARHYPERPERMEABILITY FOLLOWING HEMORRHAGICSHOCK. E. W. Childs, B. Tharakan, F. A. Hunter; Texas A&M HSC/Scott and White Hospital, Temple, TX

QS409. ARGININE CATABOLISM TO ORNITHINE INSTORED PACKED RED BLOOD CELLS IS DEPENDENTUPON THE Y� TRANSPORTER. L. Procter, P. Overall, C. Meier,P. Chang, B. Boulanger, P. Kearney, A. C. Bernard; University ofKentucky, Lexington, KY

QS410. HUMAN POST-SHOCK MESENTERIC LYMPH IN-DUCES A HYPERCOAGULABLE STATE. J. C. Eun1, E. E.Moore2, E. D. Peltz1, C. R. Hamiel1, J. R. Jordan1, A. Banerjee1;1University of Colorado Denver, Aurora, CO; 2Denver Health Medi-cal Center, Denver, CO

QS411. GLUCAGON-LIKE PEPTIDE-1 PROTECTS MESEN-TERIC ENDOTHELIUM FROM INJURY DURING INFLAM-MATION. K. C. Dozier, E. Cureton, R. Kwan, J. Sadjadi, B. Curran,G. P. Victorino; UCSF - East Bay, Oakland, CA

VASCULAR 4

QS412. EFFECT OF TOBACCO SMOKE ON ARTERIAL CELLPOPULATIONS AND STIMULATED CYTOKINE RE-SPONSES. J. Kittel, B. Arif, M. Pagano, J. A. Curci; Washington

QS413. A MURINE MODEL OF CLAUDICATION. M. A. Peck, H.Albadawi, R. S. Crawford, H. Yoo, C. J. Abularrage, V. I. Patel, M. F.Conrad, M. T. Watkins; Massachusetts General Hospital and Har-vard Medical School, Boston, MA

QS414. IDENTIFICATION OF SPECIFIC MORPHOLOGICDISEASE STATES IN PERIPHERAL ARTERIAL DISEASEUSING GENOMIC PROFILING. B. Sileshi1, D. evans2, D. M.Giangiacomo1, H. E. Achneck1, R. J. Manson1, M. W. Onaitis1, J. H.Lawson1; 1Duke University Medical Center, Durham, NC; 2OhioState University, Columbus, OH

QS415. SYSTEMIC INFLAMMATORY DETERMINANTS OFLOWER EXTREMITY REVASCULARIZATON FAILURE. K. A.O’Malley, E. Coons, R. Ungaro, S. A. Berceli, L. L. Moldawer, P. R.Nelson; Univ of Florida College of Medicine, Gainesville, FL

QS416. EFFECT OF MECHANO-CHEMICAL STIMULATIONON ENDOTHELIAL CELL (EC) EXPRESSION OF TISSUEFACTOR (TF). N. Yamashita, A. Rochier, B. Sumpio; Yale Univer-sity School of Medicine, New Haven, CT

QS417. INTEGRIN ALPHAV BETA3 MEDIATES THE ANTI-APOPTOTIC EFFECT OF DEL1 ON ENDOTHELIAL CELLS. Z.Wang, M. T. Longaker, G. P. Yang; Stanford University, Stanford, CA

QS418. ANTI-HUMAN PROTEIN S ANTIBODY INDUCES TIS-SUE FACTOR EXPRESSION THROUGH DIRECT INTERAC-TION WITH PLATELET PHOSPHOFRUCTOKINASE IN HU-MAN CORONARY ARTERY ENDOTHELIAL CELLS. D. Liao, J.Wang, P. Lin, Q. Yao, C. J. Chen; Baylor College of Medicine, Hous-ton, TX

QS419. NON-NUCLEOSIDE REVERSE TRANSCRIPTASE IN-HIBITOR EFAVIRENZ INCREASES MONOLAYER PERME-ABILITY OF HUMAN CORONARY ARTERY ENDOTHELIALCELLS. M. Jamaluddin, P. Lin, Q. Yao, C. J. Chen; Baylor Collegeof Medicine, Houston, TX

QS420. ULTRASOUND ASSESSMENT OF CAROTID INTI-MAL HYPERPLASIA IN A MOUSE MODEL. H. Chai, G. Schultz,K. Aghaie, W. Zhou; Stanford/Palo Alto VAMC, Stanford, CA

QS421. NITRIC OXIDE REGULATES THE UBIQUITIN-CONJUGATING ENZYMES CRUCIAL FOR CELL CYCLEPROGRESSION. N. D. Tsihlis, C. S. Oustwani, M. N. Banerjee, Q.Jiang, M. R. Kibbe; Northwestern University, Chicago, IL

QS422. MARCKS SILENCING INHIBITS VASCULARSMOOTH MUSCLE CELL PROLIFERATION AND NEOINTI-MAL FORMATION IN HUMAN SAPHENOUS VEIN. M. C. Mar-tin, N. D. Andersen, T. S. Monahan, J. Y. Malek, L. Pradhan, C.Ferran, F. W. LoGerfo; BIDMC, Boston, MA

QS423. SERUM LEVELS OF MATRIX METALLOPRO-TEINASE-2 ARE A MARKER OF INTIMAL HYPERPLASIA. A.Tummers, D. J. Mountain, S. S. Kirkpatrick, S. L. Stevens, D. C.Cassada, M. B. Freeman, M. H. Goldman, O. H. Grandas; Universityof Tennessee Graduate School of Medicine, Knoxville, TN

QS424. MATRIX METALLOPROTEINASE (MMP) EXPRES-SION IN ARTERIOVENOUS FISTULA (AVF) MATURATIONFOR HEMODIALYSIS. E. S. Lee, Q. Shen, M. Guo, R. L. Pitts,