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Employee No. 18568
1. Name : (first name) PARIMAL (middle name) (surname) DAS
2. Designation: PROFESSOR
3. Academic Qualifications: PhD
Sr. Degree Institution Year
B.Sc University of North Bengal, India 1984
M.Sc. Banaras Hindu University, India 1986
Ph.D. Banaras Hindu University, India 1993
4. Area of Specialization: (brief writeup, 200 words)
Research Interest:
Human molecular Genetics, Developmental Genetics, Neurogenetics, Cytogenetics,
Spermatogenesis, Cancer Genomics and Proteomics
(1) Mapping, identification and characterization of human disease genes
(2) Identification of novel candidate genes for cancer therapeutics
(3) Identification and characterization of novel protein-protein interaction underlying human
diseases with special reference to Parkinsonism.
5. Contact Information: Parimal Das, Ph.D
Professor & Coordinator
Affix your rec ent Passport size photograph
Centre for Genetic Disorders
Institute of Science
Banaras Hindu University
Varanasi – 221005
Phone : +91-542-2570280(Home)
+91-542-2366010 (Work)
Fax: +91-542-2366010
Email: parimal@bhu.ac.in
hellow_parimal@yahoo.com
6. Projects Undertaken as PI/ Co PI:
S.
No
Name of the project Duration Source of
Funding
Amount of
Funding (Rs)
1. Genetics of tooth Development:
Genes underlying tooth agenesis in
human
Role: PI
2010-2013 DBT 4500000.00
2 Prevalence and predictors of
vitamin B12 deficiency: genetic
associations for low B12 levels-
multicentre a pan Indian study
Role: Co-PI
2016-2019 DBT 49600000.00
3. Genetics of Dilated
Cardiomyopathy;
Role: Co-PI
2016-2019 DBT 12300000.00
4. Chromosomal and Molecular
Genetic analysis of Facial
Disorders” - XI Plan Research
Grant for New Faculty- From
University Grants Commission,
Govt. of India. Grant amount
Role: PI
2010-2013 UGC 270000.00
5. Genomics of Polycystic Kidney 2012-2013 UGC-UPE 200000.00
Disease – UGC-UPE Seed Grant
Role: PI
6. In House Preparation of low cost
Taq DNA Polymerase
Role: PI
2012-2013 DST-
PURSE
77000.00
7. Awards/ Recognitions if any:
1. Awarded National Merit Scholarship, Dept.of Education, Govt. of INDIA (1978-1983)
2. Awarded National Merit Scholarship, Dept.of Education, Govt. of INDIA (1983-1986)
3. Awarded National Merit Scholarship, Special Assistance Program of University Grants
Commission, Government of India (1984 -1986)
4. Junior Research Fellowship from Department of Science & Technology (DBT), Govt.of India
(1987-1991)
5. Senior research Fellowship from University Grants Commission (UGC), Govt. of India
(1991-1993)
6. Post doctoral research fellowship from DBT/NIH collaborative project (1994-1997)
7. Post doctoral fellowship (May, 1998 – June, 2004) from NIH
8. List of 10 major Publications: (in order of importance):
(1)Stockton D W*, Das P*, Goldenberg M, D’Souza R N and Patel P I (2000) Mutation of
PAX9 is associated with oligodontia. Nature Genetics 24:18-19
* Equal contributor first author
(2) Das P, Stockton D W, Bauer C, Shaffer L G, D’Souza R N, Wright J T and Patel P I (2002)
Haploinsufficiency of PAX9 is associated with autosomal dominant hypodontia Human
Genetics, 110:371-376
(3) Das P, Hai M, Elcock C, Leal S M, Brown D T, Brook A H and Patel P I (2003) Novel
missense mutation and a 288-bp exonic insertion in PAX9 in families with autosomal
dominant hypodontia. American Journal of Medical Genetics, 118A: 35-42
(4) Goldenberg M, Das P, Messersmith M, Stockton D W, Patel P I and D’Souza R N (2000)
Clinical, radiographic and genetic evaluation of a novel form of autosomal dominant
oligodontia. Journal of Dental Research, 79:1469-1475
(5) Tarpey P, Pemberton T, Stockton D, Das P, Ninis V, Edkins S, Futreal P A, Wooster R,
Kamath S, Nayak R, Stratton M and Patel P I. (2007) A novel Gln358Glu mutation in
Ectodysplasisn A associated with X-linked dominant incisor hypodontia. American
Journal of Medical Genetics 143A: 390-394
(6) Lucas R E, Vlangos C N, Das P, Patel P I and Elsea SH (2001)Genomic organization of the
~1.5 Mb Smith-Magenis syndrome critical interval: Transcription map, genomic contig,
and candidate gene analysis European Journal of Human Genetics, 9:892-902
(7) Senapat S, Thakur R, Verma SP, Mishra DP, Das P, Sripathi T, Kumar M, Rana D and
Maiti P (2015) Layered double hydroxide as effective carrier for anticancer drugs and
tailoring of release rate through interlayer anions. Journal of controlled release. January
2016. DOI: 10.1016/j.jconrel.2016.01.016. IF 7.71
(8) Sarker T, Bansal R and Das P (2014) Whole genome sequencing reveals novel non-
synonymous mutation in Ectodysplasin A (EDA) associated with non-syndromic X-
linked dominant congenital tooth agenesis. PlosOne. 10.1371/journal.pone.0106811
(IF3.23)
(9) Verma SP, Sishodia S and Das P (2015) Aqueous component of anticancer drug CRUEL
capsule induces anti-proliferative effect in Renal cell carcinoma. APJCP, 2015(8419-23),
1513-7368. IF 2.5
(10) Halder T, Raj Janak, Sharma V and Das P (2015) Novel P-TEN-induced putative kinase 1
(PINK1) variant in Indian Parkinson’s disease patient. Neuroscience Letters 605: 29-33
(IF 2.02)
9. Additional Information/ Achievements:
Invited Talks:
(1) Next Generation Sequencing: Its application in human health and diseases
Workshop on Maternal and Newborn Care:Issues and challenges, March 1-7, 2017
organnized by Institute of science, Banaras Hindu university, Varanasi
(2) PRCC_TFE3 fusion protein regulated transcriptome profiling and protein-protein
interaction in renal cell carcinoma: Symposium on “Gene-Environment interaction in
development, disease and Evolution” held at Banaras hindu University during March 5-6,
2017
(3) Genetics of Hypodontia: Unraveling the cause of human tooth agenesis- from mouse
to man: 29th
ISDR Conference, from Dec 9-11, 2016 organized by King George’s
Medical University, Lucknow
(4) Genetics of Paediatric solid tumors: Updates of Paediatric solid tumors, June 25, 2016
organized by Department of Paediatric Surgery, institute of Medical Sciences, banaras
Hindu University, Varanasi
(5) Deciphering Human Genetic Disorder : from Mouse Model to Computational
Modeling: QIP Short term Course on “Computational Biology and Neuroscience” from
June 13-18, 2016 organized by Department of Computer Science & Engineering, Indian
Institute of Technology, Banaras Hindu University, Varanasi
(6) Gene expression analysis in Neurodegerative disease model: QIP Short term Course
on “Computational Biology and Neuroscience” from June 13-18, 2016 organized by
Department of Computer Science & Engineering, Indian Institute of Technology, Banaras
Hindu University, Varanasi
(7) Genetics of Tooth Agenesis in Human: Application of Next generation Sequencing
Accelerating the scope for In vitro and In Silico Research at National Symposium on
Animal and Alternatives in Life science Research & Annual Convention of Laboratory
Animal Science Association of India (LASAI),
February 16-18, 2014 organized by Department of Zoology, Banaras Hindu University,
Varanasi
(8) Effect of Indian Traditional Ayurvedic formulation on Mouse model of Parkinson’s
disease at National Symposium on Animal and Alternatives in Life science Research &
Annual Convention of Laboratory Animal Science Association of India (LASAI),
February 16-18, 2014 organized by Department of Zoology, Banaras Hindu University,
Varanasi
(9) Decoding the cause of human tooth agenesis: from mouse to Man at International
Symposium on Developmental and Complex Disorders & 38th
Annual Conference of the
Indian Society of Human Genetics: Genomics and Community Health, December 9-11,
2012, Organized by, Banaras Hindu University, Varanasi
(10) Genetic Diversity in Indian populations: Implications in health and Disease at National
Seminar on Biodiversity and Sustainable Development & Sesquicentennial Birth-year
Celebration of Acharya Prafulla Chandra Ray, January 10 -11, 2011, organized by
Raiganj College(University), Raiganj, Uttar Dinajpur, West Bengal
(11) Human Genetic Disorders at National Seminar on Biodiversity and Sustainable
Development & Sesquicentennial Birth-year Celebration of Acharya Prafulla Chandra
Ray, January 10 -11, 2011, organized by Raiganj College(University), Raiganj, Uttar
Dinajpur, West Bengal
PROFESSIONAL EXPERTISE:
Cell Biology Techniques:
Cell separation, Cellular autoradiography,
Molecular Biology Techniques:
Gel electrophoresis (Agarose, Acrylamide, Agarose-Acrylamide composite), Bacterial
transformation, cosmid, BAC, PAC isolation, Genomic DNA isolation and Southern blotting,
RNA isolation and Northern blotting, DNA sequencing, Molecular Cloning, Nuclear run on/off
assay, Electrophoretic mobility shift assay (EMSA), Western blotting, Genomic and cDNA
library screening, PCR, RT-PCR, Pulse – field gel electrophoresis, Microsatellite typing
Cytogenetics Techniques:
Preparation of mitotic and meiotic chromosomes, Fluorescent In Situ Hybridization (FISH),
RNA In Situ Hybridization (RISH), Human chromosomes karyotyping, G-C and H band
analysis in patient (with different syndrome like Down’s etc) karyotypes
Cell culture techniques:
Long term (Primary and fibroblasts) and short term tissue cultures (including lymphocyte culture
of patients with different syndromes, Transient transfection assay
Cancer Genomics Techniques:
Human Comparative Genomic Hybridization (CGH) using high resolution BAC clones spotted
on glass slides (DNA micro array), Comparative gene expression profiling using human cDNA
and oligo array spotted on nylon membrane and subsequent analysis using Software GE Suite
Transgenic Mouse Modeling: Making transgenic mouse (cDNA and BAC) and knock out
mouse model for human disease
Others:
Construction of recombinant Baculovirus and study of the expression of recombinant protein of
biological importance.
Training in
1. Biophysical approaches towards the understanding of the conformation of macromolecules
includes Circular Dichroic and Fluorescence anysotropy measurement, gradient analysis and
thermal melting profile followed by spectrophotometry.
2. Hybridoma technology - includes preparation of murine monoclonal antibodies against T cell
antigen
3. Fermentation technology - involving growth of a specific strain of E. coli containing EcoRI
gene in a 100 litre fermenter.
4. Microinjection
MEMBERSHIP IN ACADEMIC AND PROFESSIONAL SOCIETIES
1. Member of the American Society of Human Genetics (USA)
2. Member of the New York Academy of Sciences (USA)
3. Member of the Indian Society for Cell Biology (INDIA)
4. Member of the Indian Society of Human Genetics (INDIA) – Executive Council Member-
2012-2014
Discovery:
Discovery of mutation in PAX9 gene as underlying cause for human tooth agenesis cited in
National Institute of Health press release, Texas Medical Center News, National Television
News and Radio News, Houston Chronicle Daily News Paper and in several other Web
sites. A list of URLs is attached where this discovery work has been cited
1. http://www.nidr.nih.gov/news/digest/may00_4.asp
2. http://www.nih.gov/news/pr/dec99/nidcr-29.htm
3. http://www.bcm.tmc.edu/pa/missingteeth.htm
4. http://www.odontored.cl/main.htm
5. http://www.odontored.cl/argen9.htm
6. http://www.angelfire.com/nc/kidsdental/topics13.html
7. http://www.uth.tmc.edu/uth_orgs/pub_affairs/news/releases/tooth.html
8. http://www.e-dental.com/content/news/article.asp?DocID={EAC36C32-2CC2-11D5-A770-
00D0B7694F32}&Bucket=Guest+Columnist
9. http://www.wired.com/news/medtech/0,1286,33307,00.html
10. http://www.tmc.edu/tmcnews/02_01_00/page_08.html
11. http://www.usc.edu/hsc/dental/Info/News/testimony.html
12. http://www.agd.org/consumer/topics/technology/code.html
13. ttp://www.aeldentista.com/capacitacion/capacitacion/Marco%20superior/Pagina%2042.html
14. http://www.gen-ethisches-
netzwerk.de/gid/TEXTE/ARCHIV/PRESSEDIENST_GID138/MEDIZIN/MEDIZIN.HT
M#M12
15. http://www.gen-ethisches-
netzwerk.de/gid/TEXTE/ARCHIV/PRESSEDIENST_GID138/MEDIZIN/MEDIZIN.HT
M
16. http://www.slsc.org/docs/galleries/dnazone/watt/intro_2000.shtml#gene
17. http://www.os.dhhs.gov/budget/testify/b20010516c.html
18. http://www.db.uth.tmc.edu/orthodont/sfrazier/default2.htm
19. http://www.db.uth.tmc.edu/orthodont/sfrazier/default2.htm
20. http://www.montefiorecentral.com/notysalud/ARCHIVOS/89c.html
21. http://www.parkaveperio.com/newsletter/0003.htm
22. http://www.expeditionzone.com/start_lo.cfm?story=520&business=&club=&member=
23. http://translate.google.com/translate?hl=en&sl=de&u=http://www.gen-ethisches-
netzwerk.de/gid/TEXTE/ARCHIV/PRESSEDIENST_GID138/MEDIZIN/MEDIZIN.HT
M&prev=/search%3Fq%3D%2522PAX9%2522%26start%3D60%26hl%3Den%26sa%3
DN
24. http://www3.ncbi.nlm.nih.gov/htbin-post/Omim/dispmim?167416 *
25. http://www.db.uth.tmc.edu/orthodont/sfrazier/default2.htm
26.http://www.google.com/search?q=cache:NH9FAIrRnzU:histology.musc.edu/Dental/News%2
520Item.htm+"PAX9"&hl=en
27.http://www.google.com/search?q=cache:XcRBy1hUXSc:www.uthouston.edu/forMedia/news
releases/nr2001/genetics/apply-genome.html+"PAX9"&hl=en
28. http://www.esec-povoa-lanhoso.rcts.pt/marcel/genetica1.htm
29. http://translate.google.com/translate?hl=en&sl=pt&u=http://www.esec-povoa-
lanhoso.rcts.pt/marcel/genetica1.htm&prev=/search%3Fq%3D%2522PAX9%2522%26st
art%3D150%26hl%3Den%26sa%3DN
30. http://www.dentista.it/html/ArticoloVis.asp?codArt=979&pagina=1
31. http://www.nysether.no/gjestebok.htm
10. Full List of Publications:
Book Chapter:
Halder T. and Das P. (2015). High throughput gene expression analysis: Probing the effect of an
Ayurvedic Formulation (Rasa-Sindoor) in MPTP Induced Parkinson’s disease Mouse Model. In
Animals and Alternatives in Life Science Research (pp.190-200) First Edition: Varanasi, U.P.:
Luminous Books.
Manuscript Accepted:
1. Raj S, Singh RG and Das P (2017) Mutational screening of PKD2 gene in north Indian
polycystic kidney disease patients revealed 28 genetic variations. J of Genetics.
Papers published: (36)
(36) Bansal R, Singh J.K. Singh V, Singh DDN and Das P (2017) Optimization of oxidation
temperature for commercially pure titanium to achieve improved corrosion resistance.
Journal of Materials Engineering and Performance. 26:3:969-977
(35) Halder T, Raj J, Pandey S, Kumar A, Sagar K, Chaudhury S, Sharma V, Joshi D and Das
P (2016) Screening of genetic mutations in GBA1, GIGYF2 and VPS35 in Parkinson
Disease patients from India. Journal of Genetic Disorders & Genetic Reports. 5:4
(IF:0.7)
(34) Ranjan P, Sarkar T and Das P (2016) Sequential phylogenetic characterization of Zaire
Ebola virus matrix protein VP40: an In silico analysis. IJABPT. DOI: 10.21276/Ijabpt,
http://dx.doi.org/10.21276/ijabpt (IF:1.26)
(33) Kumari R, Agrawal A, Halder T, Das P and Dubey GP (2016) Chronic poly herbal
antidepressant in the frontal cortex, hippocampus and hypothalamus of rat. Biomark J.
2:2
(32) Senapat S, Thakur R, Verma SP, Mishra DP, Das P, Sripathi T, Kumar M, Rana D and
Maiti P (2015) Layered double hydroxide as effective carrier for anticancer drugs and
tailoring of release rate through interlayer anions. Journal of controlled release.
January 2016. DOI: 10.1016/j.jconrel.2016.01.016. IF 7.71
(31) Verma SP, Sishodia S and Das P (2015) Aqueous component of anticancer drug CRUEL
capsule induces anti-proliferative effect in Renal cell carcinoma. APJCP, 2015(8419-23),
1513-7368. IF 2.5
(30) Halder T, Raj Janak, Sharma V and Das P (2015) Novel P-TEN-induced putative
kinase 1 (PINK1) variant in Indian Parkinson’s disease patient. Neuroscience Letters
605: 29-33 (IF 2.02)
(29) Upadhyay L, Singh J, Agarwal V, Pandey A. C., Verma S P, Das P and Tewari R P
(2015) Efficient water soluble nanostructured ZnO grafted O-carboxymethyl
chitosan/cuccumin-nanocomposite for cancer therapy. Process Biochemistry 50:678-
688
(28) Upadhyay L, Singh J, Agarwal V, Pandey A.C, Verma SP, Das P and Tewari R.P (2014)
In situ grafted nanostructured ZnO/Carboxymethyl cellulose nanocomposites for
efficient delivery of curcumin to cancer. J Polym Res. 21:550. DOI 10.1007/s10965-
014-0550-0. IF- 1.897
(27) Sarker T, Bansal R and Das P (2014) Whole genome sequencing reveals novel non-
synonymous mutation in Ectodysplasin A (EDA) associated with non-syndromic X-
linked dominant congenital tooth agenesis. PlosOne. 10.1371/journal.pone.0106811
(IF3.23)
(26) Singh V, Srivastava P, Verma SP, Mishra A, Das P and Singh N (2014) A new
fluorescent pyrene-pyridine dithiocarbamate probe: A chemodosimeter to detect Hg2þ in
pure aqueous medium and in live cells. Journal of Luminescence 2014;154:502–510.
(IF 2.367).
(25) Verma S, Tripathi VC and Das P. Asparagus racemosus leaf extract inhibits growth of
UOK 146 renal cell carcinoma cell line: simultaneous oncogenic PRCCTFE3 fusion
transcript inhibition and apoptosis independent cell death. Asian Pacific Journal of
Cancer Prevention 2014;15:1937-1941. (IF 1.271).
(24) Arya AK, Tripathi K, Das P. Promising role of ANGPTL4 gene in diabetic wound
healing. Int J Low Extrem Wounds. 2014;13:58-63. (IF 1.250).
(23) Chandra S, Singh AK, Singh M, Das P, Singh S, Pandey HP, Singh RG. Prolonged
elevated postprandial sugar augments severity in kidney disease: a North Indian hospital-
based study. Renal Failure 2014;36:50-54. (IF 0.941)
(22) Lazar AJF, Das P, Tuvin D, Korchin B, Zhu Q, Jin Z, warneke CL, Zhang PS, Hernandez
V, Lopez-Terrada D, Pisters PW, Pollock R E and Lev D (2007) Angiogenesis-promoting
gene patterns in alveolar soft part sarcoma. Clin Cancer Research Dec 15; 13:7314-
7321
Times cited:16 Ref: ISI Web of SCIENCE Citation Index
(21) Das P, Kotlingham D, Korchin B, Lazar A and Lev D (2007) A high prevalence of p53
exon 4 mutations in soft tissue sarcoma. Cancer 109: 2323-2333
Times cited:17 Ref: ISI Web of SCIENCE Citation Index
(20) Tarpey P, Pemberton T, Stockton D, Das P, Ninis V, Edkins S, Futreal P A, Wooster R,
Kamath S, Nayak R, Stratton M and Patel P I. (2007) A novel Gln358Glu mutation in
Ectodysplasisn A associated with X-linked dominant incisor hypodontia. American
Journal of Medical Genetics 143A: 390-394
Times cited:19 Ref: ISI Web of SCIENCE Citation Index
(19) Rosenberg NA, Mahajan S, Gonzales C, Nino-Rosales L, Ninis V, Das P, Hegde M,
Molinari L, Zapata G, Weber J L, Belmont J W and Patel P I (2006) Low levels of
genetic differentiation across Indian populations. PLoS Genetics 2(12):e215, 2052- 2061
Times cited:44 Ref: ISI Web of SCIENCE Citation Index
(18) Liu J, Zhan M, Hannay JAF, Das P, Bolshakov SV, Kotilingam D, Yu D, Lazar AF,
Pollock RE and Lev D ( 2006) Wild type p53 inhibits Nuclear Factor kB- induced matrix
metalloproteinase-9 promoter activation: implications for soft tissue sarcoma growth and
metastasis. Molecular Cancer Research 4: 803-810
Times cited:37 Ref: ISI Web of SCIENCE Citation Index
(17) Zhang L, Hannay J A F, Liu J, Das P, Zhan M, Nguyen T, Hicklin D J, Yu D, Pollock R
E and Lev D (2006) Vascular endothelial growth factor overexpression by soft tissue
sarcoma cells: implications for tumor growth, metastatis, and chemoresistance. Cancer
Research 66: 8770-8778
Times cited:32 Ref: ISI Web of SCIENCE Citation Index
(16) Pemberton T J, Das P and Patel P I (2005) Hypodontia: genetics and future perspectives.
Braz J Oral Sci. 4:695-706
(15) Das P, Hai M, Elcock C, Leal S M, Brown D T, Brook A H and Patel P I (2003) Novel
missense mutation and a 288-bp exonic insertion in PAX9 in families with autosomal
dominant hypodontia. American Journal of Medical Genetics, 118A: 35-42
Times cited:58 Ref: ISI Web of SCIENCE Citation Index
(14) Das P, Stockton D W, Bauer C, Shaffer L G, D’Souza R N, Wright J T and Patel P I
(2002) Haploinsufficiency of PAX9 is associated with autosomal dominant hypodontia
Human Genetics, 110:371-376
Times cited: 67 Ref: ISI Web of SCIENCE Citation Index
(13) Lucas R E, Vlangos C N, Das P, Patel P I and Elsea SH (2001)Genomic organization of
the ~1.5 Mb Smith-Magenis syndrome critical interval: Transcription map, genomic contig, and
candidate gene analysis European Journal of Human Genetics, 9:892-902
Times cited: 22 Ref: ISI Web of SCIENCE Citation Index
(12) Goldenberg M, Das P, Messersmith M, Stockton D W, Patel P I and D’Souza R N
(2000) Clinical, radiographic and genetic evaluation of a novel form of autosomal
dominant oligodontia. Journal of Dental Research, 79:1469-1475
Times cited: 25 Ref: ISI Web of SCIENCE Citation Index
(11) Stockton D W*, Das P*, Goldenberg M, D’Souza R N and Patel P I (2000) Mutation of
PAX9 is associated with oligodontia. Nature Genetics 24:18-19
* Equal contributor first author
Times cited: 223 Ref: ISI Web of SCIENCE Citation Index
(10) Vlangos C N, Das P, Patel P I and Elsea S H (2000) Assignment of developmentally
regulated GTP-binding protein (DRG2) to human chromosome band 17p11.2 with somatic cell
hybrids and localization to the Smith-Magenis syndrome critical interval Cytogenetics and Cell
Genetics, 88:283-285
Times cited: 2 Ref: ISI Web of SCIENCE Citation Index
(09) Shi Y P, Das P, Holloway B, Udhayakumar V, Tongren J E, Candal F, Biswas S,
Ahmed R, Hasnain S E and Lal A A (2000) Development, expression, and murine testing
of a multistage Plasmodium falciparum malaria vaccine candidate Vaccine, 18:2902-
2914
Times cited: 20 Ref: ISI Web of SCIENCE Citation Index
(08) Elsea S H, Mykytyn K, Ferrell K, Coulter K L, Das P, Dubiel W, Patel P I and
Metherall J E (1999) Hemizygosity for the COP9 Signalosome Subunit Gene, SGN3, in
the Smith-Magenis Syndrome American Journal of Medical Genetics, 87:342-348
Times cited: 17 Ref: ISI Web of SCIENCE Citation Index
(07) Krishnamurthy S, Chatterjee U, Gupta V, Prasad R, Das P, Panwar S, Hasnain S E and
Prasad R (1998) Deletion of transmembrane domain (TM) 12 of CDR1, a multidrug
transporter from Candida albicans,leads to altered drug specificity:Expression of a yeast
multidrug transporter in baculovirus expression systemYeast, 15 : pp 535 - 550
Times cited: 29 Ref: ISI Web of SCIENCE Citation Index
(06) Hasnain S E, Jain A, Habib S, Ghosh S, Chatterji U, Ramachandran A, Das P, Venkaiah
B, Pandey S, Bufeng Liang, Ranjan A, Natarajan K and Anser Azim C (1997)
Involvement of host factors in transcription from baculovirus late gene promoters - a
review Gene, 190: pp 113 – 118
Times cited: 20 Ref: ISI Web of SCIENCE Citation Index
(05) Raina A, Sulaiman IM, Ehtesham NZ, Das P, Ali A, Dogra TD and Hasnain
SE. (1996). Characterization of a human alphoid satellite DNA sequence and
its potential use in assessing genetic diversity in indian populations.
Gene, 173: pp 247 - 250
Times cited: 6 Ref: ISI Web of SCIENCE Citation Index
(04) Habib S, Burma S, Chatterjee U, Das P, Jain A, Mukherjee B, Natarajan K,
Ranjan A and Hasnain SE. (1996). Transcriptional regulation from the
AcNPV polyhedrin gene promoter. In Current Developments in Animal
Virology (ed. Wagner & Jameel), Oxford- IBH Publishers, New Delhi,
INDIA, pp 205 - 210
(03) Das P and Raman R(1994): Inactivation of mammalian X-chromosome during
spermatogenesis: Temporal expression of genes in the laboratory mouse. Journal of
Biosciences, 19: pp 513-528.
Times cited: 4 Ref: ISI Web of SCIENCE Citation Index
(02) Raman R and Das P (1991): Mammalian Sex Chromosomes III. Activity of
pseudoautosomal steroid sulfatase enzyme during spermatogenesis in Mus musculus.
Somatic Cell and Molecular Genetics, 17: pp 429-433.
Times cited: 5 Ref: ISI Web of SCIENCE Citation Index
(01) Jain A, Ranjan A, Chatterji U, Das P, Ghosh S, Habib S, Pandey S, Ramachandran A,
Venkaiah B and Hasnain SE. High level expression of heterologous genes in insect cells
is not dependent on promoters alone Invertebrate cell culture: Novel directions and
Biotechnology applications, (Editor, J. Mitsuhashi & K. Maramorosch) Academic
Press
CONFERENCE PROCEEDINGS/ABSTRACTSPUBLISHED IN JOURNALS:
(1) Sarker T, Bansal R and Das P. Identification and characterization of disease causing
genetic variant by conventional genotyping and whole genome sequencing in familial
tooth agenesis.P-26
Molecular Cytogenetics 2014, 7 (Suppl 1):P26, ISSN: 1755-8166 IF:2.66
http://www.molecularcytogenetics.org/content/7/S1/P26
(2) Raj S, Singh R G and Das P . Association of PKD1 sequence variants with
pathophysiology of ADPKD in Indian patients. Molecular Cytogenetics 2014, 7 (Suppl
1):P26, ISSN: 1755-8166 IF:2.66
http://www.molecularcytogenetics.org/content/7/S1/P31
(3) Das P. Decoding the cause of human tooth agenesis: from mouse to Man. International
Symposium on Developmental and Complex Disorders & 38th
Annual Conference
of the Indian Society of Human Genetics: Genomics and Community Health held at
Banaras Hindu University, Varanasi, INDIA, from December 9-11, 2012, Abs # IL 19,
Page # 48
(4) Bajpai S, Singh R K and Das P. Nitric oxide modulates connexins 31, 31.1 and 43
expression and cellular proliferation in diabetic wound fibroblasts. International
Symposium on Developmental and Complex Disorders & 38th
Annual Conference
of the Indian Society of Human Genetics: Genomics and Community Health held at
Banaras Hindu University, Varanasi, INDIA, from December 9-11, 2012, Abs # PP-028,
Page # 88
(5) Halder T, Sarkar T, Bansal R and Das P. DNA sequence analysis reveals exclusion of
coding region mutations in MSX1, AXIN2 and PAX9 in 3 patients of an Indian family
with hypodontia. International Symposium on Developmental and Complex
Disorders & 38th
Annual Conference of the Indian Society of Human Genetics:
Genomics and Community Health held at Banaras Hindu University, Varanasi,
INDIA, from December 9-11, 2012, Abs # PP-077, Page # 112
(6) Sarkar T, Bansal R and Das P. Mutation analysis of major candidate genes underlying
congenital tooth agenesis in human: Study of two Indian families. International
Symposium on Developmental and Complex Disorders & 38th
Annual Conference
of the Indian Society of Human Genetics: Genomics and Community Health held at
Banaras Hindu University, Varanasi, INDIA, from December 9-11, 2012, Abs # PP-109,
Page # 129
(7) Verma S P, Tripathi V C and Das P. Asparagus racemosus leaf extract inhibit UOK 146
(primary papillary renal cell carcinoma) cell growth by inducing autophagy and
PRCCTFE3 fusion protein down regulation. International Symposium on
Developmental and Complex Disorders & 38th
Annual Conference of the Indian
Society of Human Genetics: Genomics and Community Health held at Banaras
Hindu University, Varanasi, INDIA, from December 9-11, 2012, Abs # PP-127, Page #
138
(8) Bansal R, Shruti, Bansal M, Agarwal R, Das P and Rai A K. Oral manifestations in
Down syndrome-a case report. International Symposium on Developmental and
Complex Disorders & 38th
Annual Conference of the Indian Society of Human
Genetics: Genomics and Community Health held at Banaras Hindu University,
Varanasi, INDIA, from December 9-11, 2012, Abs # PP-134, Page # 141
(9) Bansal R, Rai A K and Das P. A rare form of Taurodontia with exceptionally large Yq
heteromorphic content with 47, XY+X Karyotype. 35th
Annual Conference of the Indian
Society of Human Genetics held at Sanjay Gandhi Post Graduate Institute at Lucknow,
INDIA from March 6-8,2010, ABS # MG 30, Page # 149
(10) Patel P I, Mahajan S, Gonzales C, Rosales-Nino L, Ninis V, Das P, Hegde M, Molinari
L, Zapata G, Weber J L, Belmont J W and Rosenberg N A
Genetic Structure of Asian Indian Populations: Genome-wide analysis of variation
at 1200 DNA markers.
American Society for Human Genetics Annual meeting 2005 held at salt Lake city, Utah,
USA from October 25-29, 2005, Abs# 238
(11) Patel P I, Tarpey P, Mendoza G, Gonzales C, Das P, Ninis V, Stockton D W, Scarel-
Caminaga R, Nino-Rosales L, Figuerido E, Leal S, Stratton M R, Line S. Identification
of Genes underlying hypodontia. American Society of Human Genetics annual Meeting
2004 held at Toronto, Canada from October 26 – 30, 2004, ABS# 2537/F3
(12) Rosenberg N, Gonzales C, Nino-Rosales L, Ninis V, Das P, Molinari L, Zapata G,
Weber J L, Belmont J W and Patel P I . Genetic Structure of Indian Populations.
American Society of Human Genetics annual Meeting 2004 held at Toronto, Canada
from October 26 – 30, 2004, Abs# 1159/W
(13) Das P, Rohr A, Scarel-Caminaga R, Leal SM, Figuerido EL, Line SR and Patel PI. A
novel locus for autosomal dominant hypodontia involving incisors and premolars.
American Journal of Human Genetics 73 Suppl. (5) Abs# 2323, November, 2003
(14) Das P, M Hai, Elcock C, Leal S M, Brown DT, Brook AH and Patel PI. A 288 bp exonic
insertion and novel missense mutations in PAX9 in families with autosomal dominant
hypodontia. American journal of Human Genetics 71 Suppl. (4): Abs# 2104 October,
2002.
(15) Lucas RE, Vlangos C N, Das P, Patel P I and Elsea SH. Physical and transcription map
of the SMS critical interval. American Journal of Human Genetics 67 Suppl. (4): Abs#
1472October, 2000.
(16) Das P, Stockton D W, Shaffer LG, D’Souza R, Wright JT and Patel PI. Submicroscopic
deletion encompassing the PAX9 gene associated with oligodontia.
American Journal of Human Genetics 67 Suppl. (4): Abs# 2147 October, 2000.
(17) Stockton D W , Das P, Goldenberg M, D’Souza R and Patel P I. Identification of the
gene causing autosomal dominant molar hypodontia.American Journal of Human
Genetics, 65 Suppl. (4): Abs# 250 October,1999.
(18) Goldenberg M, Stockton DW, Das P, Patel P I, D’Souza RN. A human PAX9 mutation
causes unique form of oligodontia. Journal of Dental Research 79: 3050 Sp. Iss. SI 2000.
(19) Das P, Stockton D W, Goldenberg M, D’Souza R N, Patel P I. A human PAX9 paired
domain frame shift mutation causes autosomal dominant oligodontia. Annual Retreat of
Department of Molecular and Human Genetics held at Columbia Lakes Resort, Houston,
Texas, USA (2000).
(20) KrishnaMurthy S, Chatterji U, Das P, Gupta V, Lata S, Hasnain S E and Prasad R
Functional expression of multidrug resistance gene CDR1 from C albicans and its
localization in plasma membrane using Baculovirus expression system. XX All India
Cell Biology Conference & Symposia, Mumbai, INDIA, p32 (1997):
(21) Dutta S, Das P, Malhotra P, Bhakuni V, Shukla O P, Hasnain S E and Chauhan V S
Expression of the apical membrane antigen-1, a human transmissible strain of simian
malaria in baculovirus 65th Annual Meeting of The Society of Biological Chemists
(India), IISc, Bangalore, INDIA, pp 194 (1996).
(22) Dutta S, Kocken C, Das P, Malhotra P, Bhakuni V, Hasnain S E, Thomas A and
Chauhan V S. Sequence analysis and expression of the apical membrane antigen 1
(AMA-1) of Plasmodium cynomolgi B. XIVth International Congress for Tropical
Medicine and Malaria, Nagasaki, Japan (1996) :
(23) Dutta S, Das P , Malhotra P, Bhakuni V, Hasnain S. E.,Chauhan V. S. Sequence analysis
and expression of the apical membrane antigen-1 (AMA-1) of Plasmodium cynomolgi.
Global Meet on Parasitic Diseases, N.Delhi, INDIA, p87 (1996):
(24) Shi Ya Ping , Natarajan K, Das P, Hasnain S.E., and Lal A. Expression of P. falciparum
vaccine antigen genes in the baculovirus expression system. International Conference on
Eukaryotic Expression Vector Systems: Biology and Applications, N.Delhi, INDIA, p53
(1996)
(25) Das P and Raman R. X-chromosome inactivation in mammalian testis: A gradient model
to explain step-wise inactivation of the genes. Symposium on chromosomal and
molecular basis of genetic analysis, Varanasi, INDIA, p 37 (1995).
(26) Raman R and Das P Mammalian X-chromosome: Homology with Y, chromatin
organization, and gene function during spermatogenesis.VII All India Cell Biology
Conference, Indore, INDIA, p34 (1994)
(27) Narayan G, Das P and Raman R Expression of the X-linked gene, HPRT, and its status
of methylation during spermatogenesis in mouse. Mus musculus. XV All India Cell
Biology Conference, New Delhi, INDIA, p 43 (1992)
(28) Raman R, Das P and Narayan G. Genetic inactivity and chromatin organization of X-
chromosome during spermatogenesis of mouse. First Congress of Asian-Pacific
Organization for Cell Biology, Shanghai, CHINA, p47 (1990)
(29) Das P and Raman R. Hypoxanthine phosphoribosyl Transferase activity in the light of X
chromosome inactivation during spermatogenesis in mouse. XIV All India Cell Biology
Conference, Bombay, INDIA, p 50 (1990).
(30) Das P and Raman R. X-inactivation and Steroid sulfatase activity in male germ cells of
mouse. XIII All India Cell Biology Conference, Hyderabad, INDIA, p 21 (1989)
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