Unproven methods of cancer treatment multiple enzyme therapy

After careful study of the literatureand other information available to it,the American Cancer Society has notfound evidence that treatment with theMultiple Enzyme Therapy results inobjective benefit in the treatment ofcancer in human beings.

The following is a summary of theinformation on the Multiple EnzymeTherapy in the American Cancer Society files:

Therapy

According to information providedby Dr. Franklin L. Shively, Sr., thefirst intravenous injection of the 1@Iultipie Enzyme Therapy “¿�alwaysconsistsof Chymotrypsin alone, because 3% ofthe patients react to this enzyme.― Following the first intravenous treatment,“¿�thefollowing enzymes were used intravenously in the same solution:Trypsin, Chymotrypsin, Ribonuclease,De(s )oxyribonuclease, Pepsinogen.―Two others, Lipase, and Alpha andBeta Amylase, are given orally.

The earliest item in the AmericanCancer Society files is a letter datedOctober 28, 1949, in which Dr. Shivelyexpressed his dissatisfaction, after 35years of “¿�operating on cancer,― withsurgery and radiation as methods oftreating cancer, discussed some “¿�brilliant results― which he himself had obtained with surgery, and requestedthat the Cancer Society make a carefulstudy of John Beard's book, “¿�TheEnzymes Treatment of Cancer.―

In 1955, Dr. Shively was reported tobe using Enzar in the treatment ofthirteen terminal patients, of whichthere were two survivals.

“¿�Multiple Enzyme Therapy― wasfirst reported to the Society in a manuscript with that title, submitted by Dr.Shively in 1959. In a letter in April,1965, Dr. Shively claimed: “¿�Iam liquefying cancer tissue without reactions.All cases were far advanced cases. Evenso, twelve cases are alive that shouldhave passed on.― “¿�Todate, four thousand three hundred and five (4305)intravenous infusions have been given.There has been one hundred ninetythree hospital admissions.― In mostcase reports described by Dr. Shively,however, patients were treated withother modalities, surgery, radiation,etc., together with the Multiple EnzymeTherapy. This makes it impossible togive credit for beneficial results obtained, as Dr. Shively does, to the Multiple Enzynie Therapy alone.

Dr. Shively believes that cancer iscaused by an enzyme deficiency or incapacity which allows new cells to growwithout built-in enzymatic controls.With his intravenous injections ofmultiple enzymes, he is seeking to helpthe body cells overcome this deficiency.

According to an editorial in TheRichmond (Indiana) News, Leader,October 14, 1966, “¿�Forten years Dr.Shively has been giving enzymes intravenously to patients at Dayton's MiamiValley Hospital. All of his treatmentshave been under the supervision of thehospital's medical staff board of review.―

The early treatments, according toDr. Shively in a letter to the Societydated October 26, 1959, were givenwithout pay for two years and ninemonths. He added: “¿�Moierecently, I

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Unproven Methods of Cancer TreatmentThe following statement concerning the Multiple Enzyme Therapy proposed

for the ti-eatment of cancer by Franklin L. Shively, Si-., M.D., was recently distributed to the 58 Divisions of the American Cancer Society for their infoi-mation.

Multiple Enzyme Therapy

have charged $150.00 for one month'streatment; this does not cover my expense.―

ProponentAccording to the American Medical

Association Directory, 1965, FranklinL. Shively, Sr., M.D., 58 Grafton Avenue, Dayton, Ohio 45406, was boin in1887; received an M.D. degree fromNorthwestern University MedicalSchool in 1914, and was licensed topractice medicine in Ohio the sameyear. He is reported to be conductingresearch in internal medicine.

FederalActionIn a speech to the Senate, “¿�Isthe

Food and Drug Administration Hamstringing Cancer Research ?“publishedin the Congressional Record for October 5, 1966, Senator Edward Long discussed Dr. Shively's difficulties withthe Food and Drug Administration.2An editorial in The Richmond NewsLeader, reviewing this speech, described these difficulties as follows:“¿�OnMai'ch 13, 1964, the FDA oi-dered

Dr. Shively to file for a special exemption to continue his work; the exemption was granted on April 24.. . . Then

the exemption was terminated onJuly 28, 1964 because there were noformal studies on the safety of enzymetreatments of animals—despite thefact that properly supervised treatments has been safely underway withpatients for a decade.... From Febiuai-y 1965 to December, the FDA quibbled about animal safety data. In January and March of this year, Dr. Shivelypresented proposals foi animal safetyexperiments which would cost him$25,000, all of it privately raised. TheFDA made no reply until August ofthis year, when outside inquiries beganto ask why these proposals by a man ofhigh i'eputation were not even answeu-ed. The FDA is still raising minorobjections.―

References

1. The ruse of Dr. ,Shirel!/. Editoriul. The Theh 1000(1(Indiana) .Ve us Lear/er, October 14, it#i;e.

2. Lon@i, E. V. : Is the food ((ill! (/(uf/ (((Ilflil(i.ltl(f—timi ha in st n iiq nq ranr(r lea-arc/i Coisilresswnull:c(or(/ 11.2; October ;@,1@)G6.

THE TENTH INTERNATIONAL CANCER CONFERENCE,under the auspicesof the InternationalUnion Against Cancer, will be held May 22-29, 1970, Houston,Texas. Featuresof the Congresswill be Congresslectures, panel discussions,scientificexhibits, commercial exhibits, and films.The National Organizing Committee for the Congressconsistsof: R. Lee Clark, M.D., Chairman;Murray M. Copeland, M.D., Secretary General; and The University of Texas M. D. AndersonHospital and Tumor Institute, Secretariat, 6723 Bertner Avenue, P. 0. Box 20465, AstrodomeStation, Houston,Texas 77025, Cable Address CANCONG.

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