Ameloblastoma

A CASE REPORT ON AMELOBLASTOMA

INTRODUCTION True neoplasm of odontogenic epithelium Term “ Ameloblastoma” coined by Churchill –

1934. “Unicentric, nonfunctional, intermittent in

growth, anatomically benign, clinically persistent”.

2nd most common odontogenic neoplasm, & represents 1% of all oral odontogenic epithelial tumors & 11% of all odontogenic tumors.

CASE REPORT

60 year old female c/o swelling on right cheek since 2 years.

Extra orally; 1 year back

Swelling 1 year back

Present size

Intra oral swelling

1 year back

Present oral swelling

Provisional diagnosis –

AMELOBLASTOMA Differential diagnosis –

1) Odontogenic Keratocyst

2) Central giant cell granuloma

3) CEOT

4) Odontogenic myxoma

5) COC

INVESTIGATIONS Radiological – OPG, lateral occlusal

mandibular radiograph Complete blood picture, CT, BT Incisional biopsy

Present radiograph

1 year back

Bicortical expansion

Differential diagnosis –

1) central giant cell granuloma

2) odontogenic Keratocyst

3) odontogenic myxoma

4) ossifying fibroma

central giant cell granuloma

Odontogenic Keratocyst

Right body and ramus of the mandible

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Odontogenic myxoma

DISCUSSION

Etiology – Varied origin cell rests of enamel organ Epithelium of odontogenic cysts Disturbances of developing enamel organ Basal cells of surface epithelium of the

jaws Heterotopic epithelium in other parts of the

body

CLINICAL FEATURES Wide age range, but uncommon in

children and adults < 20 yrs of age Posterior mandible Asymptomatic, often discovered on

routine radiographs As tumor grows, painless enlargement

may be noted

RADIOLOGICAL FEATURES Unilocular radiolucency, especially early

lesions that often progress to multilocular (soap-bubble, honeycomb)

May be associated with impacted tooth Cortical expansion and thinning Resorption of adjacent tooth roots,

displacement of teeth can be seen