Stereochemistry of biaryls and ansa compounds

April 12, 2023 1By Mohd Anzar Sakharkar

April 12, 2023 2By Mohd Anzar Sakharkar

STEREOCHEMISTRY OF BIARYLS

April 12, 2023 3By Mohd Anzar Sakharkar

April 12, 2023 4By Mohd Anzar Sakharkar

R

R R

R COOHCOOH

April 12, 2023 5By Mohd Anzar Sakharkar

P-3 b b

a a

b a

a b

b b

a a

90o 180o 270o 360o

Interplanar angle

b a

a b

April 12, 2023 6By Mohd Anzar Sakharkar

April 12, 2023 7By Mohd Anzar Sakharkar

NO2

HOOC

NO2

COOH

R

NO2

O2N

COOH

COOH

Al(CH3)3

H

H

HS

Al3(CH3)

H

H

F

April 12, 2023 8By Mohd Anzar Sakharkar

X X

H2C CH2

(CH2)n

April 12, 2023 9By Mohd Anzar Sakharkar

X X

H2C CH2

(CH2)n

April 12, 2023 10By Mohd Anzar Sakharkar

R-S NOMENCLATURE:

April 12, 2023 11By Mohd Anzar Sakharkar

O O

H2C CH2

(CH2)n

Pilot Atom 2

H3C CHIRAL PLANE

2

2

O O

H2C CH2

(CH2)n

CHIRAL PLANE

Pilot Atom

CH3

R S

O

O

H2CCH2

(CH2)n

Pilot Atom

H3C

CHIRAL PLANE

S

1 1

1

3 3

3

April 12, 2023 12By Mohd Anzar Sakharkar

April 12, 2023 13By Mohd Anzar Sakharkar

April 12, 2023 14By Mohd Anzar Sakharkar

April 12, 2023 15By Mohd Anzar Sakharkar