View
31
Download
0
Category
Preview:
Citation preview
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Cholinergic or Parasympathomimetic Drugs These drugs are classified as either direct or
indirect acting agents. Direct acting drugs act directly on the
parasympathetic receptors. Indirect acting drugs work by either of two
methods. They can cause the release of the
neurotransmitter which then goes to the receptor site or they inhibit the enzyme cholinesterase.
5
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc. 10
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
These drugs prevent the action of acetylcholine at postganglionic parasympathetic endings.
Acetylcholine is released but its receptor site is completely blocked by anticholinergic drugs.
These drugs only block muscarinic receptors.
11
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Belladonna Alkaloids: Atropine Methscopolamine Homatropine Belladonna Scopolamine hydrobromideSynthetic Derivatives
GlycopyrrolatePropanthelineTertiary Amines
Benztropinedicyclomine
19
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Catecholamines Dobutamine Dopamine Epinephrine NorepinephrineNoncatecholamines
Mephentermine and phenylephrineAlbuterolTerbutalineephedrine
19
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Alpha-adrenergic blockers ergotamine Phentolamine Prazosin trazosin Beta-adrenergic blockers
Nonselective:CarvedilolPindololPropanololtimolol
19
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Selective:AcebutololAtenololEsmololMetoprolol tartrate
19
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Types: Muscle Relaxants differ by the location and
mechanism that muscle contraction is inhibited
1. Peripherally (Direct-acting)- within the muscle2. Centrally- within the spinal cord
Muscle Relaxants
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
A.PERIPHERALLY (Direct) ACTING- Used in MS, cerebral palsy and cord injury Dantrolene Succinylcholine
B.Centrally acting Skeletal muscle relaxantsNote: these drugs are used to control spastic muscle tone
as in epilesy ,multiple scelerosis ,cerebral palsy, stroke,
Used to treat acute spasms caused by: anxiety Inflammation Pain trauma
08/21/17 11
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
For intermittent or chronic spasms: Diazepam Baclofen Tizanidine
For acute spasms: Carisoprodol Chlorphenesin Chlorzoxazone Cyclobenzaprine Metaxalone Methocarbamol Orphenadrine Tizanidine
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Any situation where impaired relaxation interferes with function
Before surgery Allows intubation Relax abdominal muscles Orthopedic procedures
fibromyalgia
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Non depolarizing- competitive or stabilizing drugs derived from curare alkaloids and synthetically similar compounds: Atracurium Cisatracurium Doxacurium Mivacurium Pancuromium Rocuromium Tubocurarine vecuromium
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Depolarizing blocking drugs: Succinylcholine – only depolarizing blocking
drug. Although it’s similar to the nondepolarizing blockers in its therapeutic effect, its mechanism of action differs.
Acts like acetycholine but it is not inactivated by cholinesterase.
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Parkinson’s disease (PD) is a progressive disorder of movement that occurs mainly in the elderly. The chief symptoms are: Tremor at rest, usually starting in the hands (‘pill-
rolling’ tremor), which tend to diminish during voluntary activity
Muscle rigidity, detectable as an increased resistance in passive limb movement
--Bradykinesia Suppression of voluntary movements (hypokinesis),
due partly to an inherent inertia of the motor system, which means that motor activity is difficult to stop as well as to initiate.
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Sometimes called parasympatholytic drugs They inhibit the action of acetylcholine Two classes: 1. Synthetic tertiary amines
Benztropine Biperidine hydrocholoride Biperiden lactate Procyclidine trihexyphenidyl
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
2. Antihistamines ( diphenhydramine) –that have anticholinergic properties, which is effective in treating the symptoms of Parkinson’s disease.
DOPAMINERGIC DRUGS• Levodopa• Carbidopa-levodopa• amantadine
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Used as adjuncts to levodopa-carbidopa therapy in manging patients with Parkinson’s disease who experience the wearing –off effect at the end of dosing interval.
tolcapone entacapone
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Inhibit neuromuscular transmission and are prescribed for:
Long-term management of chronic epilepsy (recurrent seizures)
Short-term management of acute isolated seizures not caused by epilepsy, such as those occuring after trauma or brain surgery.
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Major classes: Hydantoins- Ex. phytoin and phenytoin sodium
Barbiturates- Ex. phenobarbital for long term treatment of epilepsy
Iminostilbenes- Ex. Carbamazepine for partial and generalized tonic-clonic seizures; mixed seizure types; complex partial seizures
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Benzodiazepines- Ex: clonazepam;diazepam(parenteral form);lorazepam;clorazepate
Carboxylic acid derivatives- Ex. Valproic acid also available as: valproate; divalproex
Phenyltriazines- FDA approved as adjunctive therapy for adults who have partial seizures and for children older than age 2 with generalized seizures.
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
1-(aminomethyl) cyclohexane-acetic acid- Ex. Gabapentin(GABA agonist)
Carboxamides- Ex: Oxcarbazepine
Sulfamate-substituted monosaccharides
Succinimides-Ex: ethosuximide and methsuximide-used to manage absence seizures
Sulfonamides- Ex: Zonisamide
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Common primary headache disorders: pounding, pulsating, or throbbing
May be preceded by an aura
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
1) 5-HT1-receptor agonists (triptans)AlmotriptanEletriptanfrovatriptan\NaratriptanRizatriptanSumatriptanZolmitriptan
2) Ergotamine preparationsErgotaminedihydroergotamine
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Pain control and antipyretic (fever control) and anti-inflammatory
Salicylates Choline magnesium trisalicylateCholine salicylateDiflunisalSalsalateSodium salicylateAcetaminophen
Nonsteroidal anti-inflammatory drugs Phenazopyridine hydrochloride
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Opioid agonistsCodeineFentanyl citrateHydrocodoneHydromorphone hydrochlorideLevorphanol tartrateMeperidine hydrochlorideMethadone hydrochlorideMorphine sulfate
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Mixed opioid agonist-antagonistsBuprenorphine hydrochlorideButorphanol tartrateNalbuphine hydrochloridePentazocine hydrochloride
Opioid antagonistsNaloxone hydrochlorideNaltrexone hydrochloride
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Inhalation anesthetics Desflurane Enflurane Halothane Isoflurane Nitrous oxide sevoflurane
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Intravenous anestheticsBarbiturates (methohexital, thiopental)Benzodiazepines (midazolam)Dissociatives (ketamine)Hypnotics(etomidate, propofol)Opiates (fentanyl, sufentanil)
Local anesthetics“amide” drugs (with nitrogen in the molecular chain
lidocaine, prilocaine,bupivacaine)“ester” drugs (with oxygen in the molecular chain
chloroprocaine, cocaine,procaine and tetracaine.)
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Topical anestheticsLidocainetetracaine
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Cardiac glycosides Digoxin PDE Inhibitors (phosphodiesterase)
InamrinoneMilrinone
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Class IA Disopyramide phosphate Procainamide hydrochloride Quinidine (sulfate and gluconate) Class IB
Lidocaine hydrochlorideMexiletine hydrochlorideTocainidine hydrochloride
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Class IC Flecainidine acetate Moricizine Propafenone hydrochloride Classs II
Composed of beta-adrenergic antagonists, or beta-adrenergic blockers
AcebutololEsmololPropranolol
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Class III Amiodarone hydrochloride Dofetilide Ibutilide Sotalol
Class IV-composed of calcium channel blockers Verapamil Diltiazem
Adenosine
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Nitrates Amyl nitrite Isosorbide dinitrate Isosorbide mononitrate Nitroglycerin Beta-adrenergic antagonists- beta blockersAtenololCarvedilolMetroprolol tartrateNadololPropanolol hydrochloride
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Calcium channel blockers Amlodipine besylate Diltiazem hydrochloride Nicardipine hydrochloride Nifedipine Verapamil hydrochloride
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
SYMPATHOLYTIC DRUGS -inhibits or blocks the sympathetic nervous
systemCentral-acting sympathetic Nervous System
Inhibitors: Clonidine hydrochloride Methyldopa Alpha-adrenergic blockers
Doxazosin mesylatePhentolamineprazosin hydrochloride
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Mixed alpha-and beta-adrenergic blockers Carvedilol Labetalol Norepinephrine depletors
Guanadrel sulfateGuanethidine monosulfate
VASODILATING DRUGSDirect vasodilators:DiazoxideMinoxidilHydralazine hydrochloride
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
ACE INHIBITORS Catopril Enalapril Ramipril ANGIOTENSIN II RECEPTOR BLOCKERS Losartan Olmesartan Valsartan Telmisartan
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Thiazide and thiazide-like diuretics Benzthiazide Hydrochlorothiazide Methyclothiazide MetolazoneLoop diurecticsBumetanideEthacrynic acidFurosemidetorsemide
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Potassium-sparing diurectics Amiloride Spironolactone Triamterene
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Bile-sequestering drugs Cholestyramine Colestipol hydrochloride ColesevelamFibric acid derivativesFenofibrateGemfibrozilHMG –CoA reductase Inhibitors (statins)Atorvastatin calciumFluvastatin sodiumsimvastatin
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Nicotinic Acid (niacin) Cholesterol absorption inhibitors
Ezetimibe
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Iron Ferrous sulfate
Vitamin B12 Cyanocobalamin hydroxocobalamin
Folic acid Erythropoietin agents
Epoetin alfa darbepoetin
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Heparin Oral Anticoagulants
Warfarin sodium Antiplatelet
Aspirin Clopidogrel Dipyridamole
Direct thrombin inhibitors Argatroban Lepirudin Bivalirudin
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Alteplase Reteplase Streptokinase urokinase
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Short-acting Albuterol (systemic,inhalation) Terbutaline (systemic)
Long-acting Formoterol(inhalation) Salmeterol(inhalation)
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Ipratroprium bromide
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Inhalation: Budesonide Fluticasone propionate
Oral: Prednisolone Prednisone
I.V: Hydrocortisone sodium succinate Methylprednisolone sodium succinate
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
montelukast
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
nedocromil Cromolyn sodium
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Theophylline Aminophylline
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
guaifenesin
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Benzonatate Codeine Dextromethorphan hydrobromide Hydrocodone bitartrate
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Ephedrine Phenylephrine Pseudoephedrine
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Systemic antibiotics Amoxicillin Clarithromycin Metronidazole Tetracycline
Antacids Aluminun carbonate gel Calcium carbonate Magnesium hydroxide
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
H2-receptor antagonists Cimetidine Famotidine Nizatidine Ranitidine
Proton pump inhibitors Esomeprazole Omeprazole pantoprazole
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Adsorbent Activated charcoal
Antiflatulent Simethicone
Digestive Dehydrocholic acid Apncreatin Pancrelipase Amylase protease
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Opioid-related Loperamide
Kaolin and pectin 5-HT3 receptor antagonists Hyperosmolar laxatives
Glycerin Lactulose Saline compounds (magnesium salts,sodium
phosphate)
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Dietary fiber and related bulk-forming laxatives Methylcellulose Polycarbophil
Emollient laxatives Calcium, potassium,and Sodium salts of docusate
Stimulant laxatives Bisacodyl Castor oil
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Lubricant laxatives Mineral oil
5-HT4 receptor partial agonists tegaserol
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Antiemetics Antihistamines
Buclizine hydrochloride, diphenhydramine hydrochloride
Phenothiazines Chlorpromazine hydrochloride Promethazine hydrochloride
Serotonin 5-HT3 receptor antagonists Dolasetron granisetron
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Emetics Ipecac syrup
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Aminoglycosides Amikacin sulfate Gentamicin sulfate Streptomycin sulfate Neomycin sulfate
Penicillins Amoxicillin Ampicillin Carbenicillin
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Cephalosporins Cefazoline Cefaclor Ceftazidime
Tetracyclines Demeclocycline hydrochloride Doxycycline hyclate
Macrolides Erythromycin estolate Azithromycin
Vancomycin
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Carbapenems Meropenem
Monobactams Aztreonam
Fluoroquinolones Ciprofloxacin Levofloxacin
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Synthetic nucleosides Acyclovir
Pyrophosphate analogs Foscarnet
Influenza A and syncytial virus drugs Amantadine Ribavirin
Nucleoside analog reverse transcriptase inhibitors zidovudine
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Non-nucleoside reverse transcriptase inhibitors Delavirdine Efavirenz
Nucleotide analog reverse transcritase inhibitors Tenofovir
Protease Inhibitors Amprenavir ritonavir
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Drug regimens for treating TB Isoniazid Rifampin Pyrazinamide Streptomycin or ethambutol
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Polyenes Amphotericin B Nystatin
Flucytosine Imidazole
Ketoconazole Synthetic triazoles
Fluconazole
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Glucan synthesis inhibitors Caspofungin
Synthetic allylamine derivatives terbinafine
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Histamine -1 receptor antagonists Diphenhydramine hydrochloride Loratidine Meclizine hydrochloride
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Glucocorticoids Beclomethasone Cortisone Prednisone Prednisolone
Mineralocoticoids Aldosterone Fludrocortisone acetate
Other immunosuppressants Azathioprine cyclosporine
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Probenecid SulfinpyrazoneOther antigout drugs:
allopurinol colchicine
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Benzodiazepines Lorazepam Diazepam Alprazolam
Barbiturates Amobarbital Phenobarbital Pentobarbital sodium
Nonbenzodiazepines-nonbarbiturates Zolpidem zaleplon
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Buspirone
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Selective serotonin reuptake inhibitors Citalopram hydrobromide Escitalopram oxalate Sertraline hydrochloride
Tricyclic antidepressants Amoxapine Doxepin hydrochloride Doxepin hydrochloride
Monoamine oxidase inhibitors (MAOIs) Hydrazines
Lithium
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Atypical antipsychotics Aripiprazole Clozapine Olanzapine
Typical antipsychotics Butyrophenones:
Haloperidol Dibenzoxazepines
Loxapine succinate Dihydroindolones
Molindone hydrochloride Thioxanthenes
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Dextroamphetamine Pemoline Methylphenidate hydrochloride
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Insulin Oral antidiabetic drugs
Chlorpropamide Tolazamide Tolbutamide metformin
Glucagon Estrogens
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Anterior Pituitary drugs Adrenocorticotorpics thyrotropics
Posterior pituitary drugs Vasopressin Oxytocin
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Thyroid drugs Thyroid USP thyroglobulin thyrotropics
Antithyroid drugs Thioamides: propylthiouracil and methimazole Iodides: iodine and radioactive iodine
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Potassium Potassium acetate Potassium bicarbonate Potassium chloride Potassium gluconate Potassium phosphate
Calcium Calcium carbonate Calcium chloride Calcium citrate
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Alkalinizing Sodium bicarbonate Sodium citrate Sodium lactate
Acidifying drugs Acetazolamide Ammonium chloride Ascorbic acid
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Nitrogen mustards melphalan chlorambusil estramustine
Alkyl sulfonates Busulfan Alkyl sulfonate
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Nitrosoureas carmustine lomustine streptozocin
Triazenes Dacarbazine
Ethylenimines Thiotepa
Alkylating–like drugs Carboplatin Cisplatin oxaliplatin
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Folic acid analogues Pyrimidine analogues
Capecitabine Cytarabine Fluorouracil
Purine analogues Cladribine Thioguanine pentostatin
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Anthracyclines Daunorubicin Doxorubicin
Bleomycin sulfate mitomycin
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Aromatase Inhibitors Type 1 or steroidal Type 2 or nonsteroidal
Anastrozole and letrozole
Antiestrogens Tamoxifen citrate Fulvestrant
Androgens Testolactone Testosterone propionate
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Antiandrogens Flutamide Nilutamide Bicalutamide
Progestins Hydroxyprogesterone caproate Megestrol acetate
Gonadotropin-releasing hormone analogues Goserelin acetate Leuprolide acetate Triptorelin pamoate
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Vinca alkaloids vinblastine vincristine
Podophyllotoxins etoposide teniposide
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
Alemtuzumab Rituximab
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
irinotecan topotecan
Mosby items and derived items © 2007 by Mosby, Inc., an affiliate of Elsevier Inc.
irinotecan topotecan
Recommended