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E-DES:
Eindhoven Diabetes Education Simulator
Anne Maas (anne.maas@mmc.nl)
Carola van Pul1, Ward Cottaar2, Peter Hilbers2, Natal van Riel2, Harm
Haak1.1 Máxima Medical Center, Eindhoven. 2 Eindhoven University of Technology, Eindhoven.
Diabetes
Norris 2002 Diabetes Care 25:1159–1171, 2002
Current diabetes
self-management
education
???
food
insulin–
stress +physical activity–
+
blood glucose
level
Improve efficacy through eHealth solutions
• More patients can benefit
• Reduced costs
• Opportunity to practice
883 diabetes apps for the iPhone alone…
so why another one?
• Most apps do not differentiate between
T1DM and T2DM.
• Focus on simple logging of blood
glucose instead of self-management.
• Only 20% give individualized feedback.
• Consumer apps don’t give evidence-
based guidance.
www.sugarpal.nl
Objective
• Individualized simulator (game)
• Predict glucose & insulin values over time
• Type 1 and type 2 patients
• Input: food, medication, exercise, stress,
illness
Physiological model
Models for healthy people eating different
meals
0 60 120 180 240 300 360
4
5
6
7
8
time [min]
Gp
l [m
mo
l/L
]
0 60 120 180 240 300 360
4
5
6
7
8
time [min]
Gp
l [m
mo
l/L
]
0 60 120 180 240 300 360
4
5
6
7
8
time [min]
Gp
l [m
mo
l/L
]
0 60 120 180 240 300 360
4
5
6
7
8
time [min]
Gp
l [m
mo
l/L
]
0 60 120 180 240 300 360
4
5
6
7
8
time [min]
Gp
l [m
mo
l/L
]
tuna sandwich and muffinD = 96g; GL = 59
wholemeal wheat breadD = 50g; GL = 32
basmati riceD = 50g; GL = 29
corn pastaD = 50g; GL = 37
cereal with milk and fruitD = 50g; GL = 33
Current work: validating the diabetes model
• Currently gathering type 1 and type 2 data
• 84 patients, 47 timepoints, 180 mL blood
• Type 2 divided in 6 classes
Next phase: user interface
Take home messages
We are developing E-DES:
• a scientifically validated educational simulator
for patients with diabetes type 1 and 2
• it models different meals and can be
individualized
• it distinguishes different groups of diabetes
type 2 patients, rather than treating them as 1
• it will become freely available
We are still looking for partners to further
develop the user interface!
• N van Riel
• P Hilbers
• W Cottaar
• C van Pul
• H Haak
Sponsored by Novo Nordisk
The team
www.diabetessimulator.wordpress.com
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