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STATISTICAL
POWER
CHRISTIANA DATUBO-BROWN
TOPICS
What is Statistical Power? Why is it important?
Estimating Statistical Power
Useful Software
An example: Mobile Health study
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WHAT IS POWER?
Power = the probability of correctly rejecting a false null
hypothesis (when the alternative hypothesis is true)
Power = 1 - β
More powerful experiment = better chance of rejecting a false null
hypothesis
Thus, reducing the likelihood of Type II error
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WHAT IS POWER?
Statistical power can help answer questions like these:
How large must my sample size be?
How should I design my experiment?
Which measures/test should I use?
I can get about X amount of people in my study, will I have
enough power?
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ESTIMATING STATISTICAL
POWER
One should estimate statistical power during the design phase of
the study
Especially after:
Selecting measures
Choosing a valid statistical test
Power can be estimated for many types of tests (t-Tests, ANOVA,
regression, etc.)
Very common in treatment effectiveness research
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ESTIMATING STATISTICAL
POWER
It’s OK to try out different designs and statistical tests
in the search for the most powerful or practical study.
However, these trials must be done before conducting
the study.
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ONE WAY TO ESTIMATE POWER
Use population means and standard deviations (or best guesses)
Example: Say you want to assign 20 individuals to two groups,
control (C) and treatment (T)*.
Table 1: Population Parameters
Mean
Standard
Deviation
Control 9.64 3.17
Treatment 6.58 3.03
Step 1. Draw 20 random
observations from a population
with scores like the C group
Step 2. Draw 20 random
observations from a population
with scores like the T group
Step 3. Calculate the t statistic
Step 4. Repeat above steps 9,999
more times
To estimate how much power this study
will have, you can follow these steps
*Example from Howell (2013)
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ONE WAY TO ESTIMATE POWER
86% of the results greater than
2.024
Power (given the parameter
estimates) is .86
*Howell (2013), pg 221
Out of the
10,000 t values,
how many are
greater than
tcrit(38) = 2.024?
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THE TRADITIONAL WAY
We know that power depends on the degree of overlap between
sampling distributions
*Howell (2013), pg 2229
THE TRADITIONAL WAY
Overlap/power depends on:
Statistical test
Alpha level
Sample size
Effect size (ES)μT – μC
σ
Means for treatment and
control populations
Pooled standard
deviation
ES =
10
USEFUL SOFTWARE
Commercial:
SAS sample and power size
PASS sample size software
Free:
R package pwr
G*Power
And many more!
I will be using G*Power to illustrate an example
Download G*Power here:
http://www.gpower.hhu.de/
11
MOBILE HEALTH STUDY
Research Question:
Will regular (text) messages and targeted messages increase drug
adherence for adult patients with diabetes when compared to
diabetic patients who do not receive messages?
Control Group (G1): No messages
Treatment Group 1 (G2): regular messages
Treatment Group 2 (G3): targeted messages
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MOBILE HEALTH STUDY
What we know
Dependent variable: drug adherence (range=5-25)
Independent variables: G1, G2, G3
Minimally importance difference: 3
(a difference of 3 points is needed to show clinical significance)
Want power = .80
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MOBILE HEALTH STUDY
1. Choose test
Here, we will be using an
omnibus F test of a one-
way ANOVA with 3 levels
(or groups)
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MOBILE HEALTH STUDY
G*Power offers plenty of
tests
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MOBILE HEALTH STUDY
2. Determine the effect size
Means and standard deviations are guided by our hypotheses and previous research
SD = 3
Means:G1= 12,
G2 = 13, & G3 = 15*change power and group size
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MOBILE HEALTH STUDY
3. Calculate estimates
Our results:
To achieve a power of .80 and given the parameter estimates,
We will need at least 60 patients (20 per group) in the study
*note effect size
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MOBILE HEALTH STUDY
Alternatively, you can
manually enter the effect
size.
Again, guided by
hypotheses and previous
research
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A NOTE ON PRACTICALITY
That last test (with ES = .20) calls for a total sample size of 246 patients.
What if that’s not feasible?
You can:
Revisit your study design
Revise hypotheses, attempt other tests, change measures, etc.
Or, work backwards. Estimate power from a sample size that is practical
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REFERENCES
Howell, D., C. (2013). Power. In J. D. Hage (Ed.).
Statistical methods for psychology (8th ed., pp. 229-
249). Belmont, CA: Wadsworth, Cengage Learning.
Kraemer, H. C., Thiemann, S. (1987). How many
subjects? Newbury Park, CA: Sage Publications, Inc.
Lipsey, M. W. (1990). Design sensitivity: Statistcal
power or experimental research. Newbury Park, CA:
Sage Publications, Inc.
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BIG THANKS
To Dr. Philippe Gaillard for his wonderful guidance (and books!)
Also to the STAT 7970 class - wonderful audience.
To contact me
email - [email protected]
visit - http://cdatubo.weebly.com/
connect - http://www.linkedin.com/in/cdatubo
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