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STATISTICAL POWER CHRISTIANA DATUBO-BROWN

Statistical Power

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Page 1: Statistical Power

STATISTICAL

POWER

CHRISTIANA DATUBO-BROWN

Page 2: Statistical Power

TOPICS

What is Statistical Power? Why is it important?

Estimating Statistical Power

Useful Software

An example: Mobile Health study

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Page 3: Statistical Power

WHAT IS POWER?

Power = the probability of correctly rejecting a false null

hypothesis (when the alternative hypothesis is true)

Power = 1 - β

More powerful experiment = better chance of rejecting a false null

hypothesis

Thus, reducing the likelihood of Type II error

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Page 4: Statistical Power

WHAT IS POWER?

Statistical power can help answer questions like these:

How large must my sample size be?

How should I design my experiment?

Which measures/test should I use?

I can get about X amount of people in my study, will I have

enough power?

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Page 5: Statistical Power

ESTIMATING STATISTICAL

POWER

One should estimate statistical power during the design phase of

the study

Especially after:

Selecting measures

Choosing a valid statistical test

Power can be estimated for many types of tests (t-Tests, ANOVA,

regression, etc.)

Very common in treatment effectiveness research

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Page 6: Statistical Power

ESTIMATING STATISTICAL

POWER

It’s OK to try out different designs and statistical tests

in the search for the most powerful or practical study.

However, these trials must be done before conducting

the study.

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Page 7: Statistical Power

ONE WAY TO ESTIMATE POWER

Use population means and standard deviations (or best guesses)

Example: Say you want to assign 20 individuals to two groups,

control (C) and treatment (T)*.

Table 1: Population Parameters

Mean

Standard

Deviation

Control 9.64 3.17

Treatment 6.58 3.03

Step 1. Draw 20 random

observations from a population

with scores like the C group

Step 2. Draw 20 random

observations from a population

with scores like the T group

Step 3. Calculate the t statistic

Step 4. Repeat above steps 9,999

more times

To estimate how much power this study

will have, you can follow these steps

*Example from Howell (2013)

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Page 8: Statistical Power

ONE WAY TO ESTIMATE POWER

86% of the results greater than

2.024

Power (given the parameter

estimates) is .86

*Howell (2013), pg 221

Out of the

10,000 t values,

how many are

greater than

tcrit(38) = 2.024?

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Page 9: Statistical Power

THE TRADITIONAL WAY

We know that power depends on the degree of overlap between

sampling distributions

*Howell (2013), pg 2229

Page 10: Statistical Power

THE TRADITIONAL WAY

Overlap/power depends on:

Statistical test

Alpha level

Sample size

Effect size (ES)μT – μC

σ

Means for treatment and

control populations

Pooled standard

deviation

ES =

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Page 11: Statistical Power

USEFUL SOFTWARE

Commercial:

SAS sample and power size

PASS sample size software

Free:

R package pwr

G*Power

And many more!

I will be using G*Power to illustrate an example

Download G*Power here:

http://www.gpower.hhu.de/

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Page 12: Statistical Power

MOBILE HEALTH STUDY

Research Question:

Will regular (text) messages and targeted messages increase drug

adherence for adult patients with diabetes when compared to

diabetic patients who do not receive messages?

Control Group (G1): No messages

Treatment Group 1 (G2): regular messages

Treatment Group 2 (G3): targeted messages

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Page 13: Statistical Power

MOBILE HEALTH STUDY

What we know

Dependent variable: drug adherence (range=5-25)

Independent variables: G1, G2, G3

Minimally importance difference: 3

(a difference of 3 points is needed to show clinical significance)

Want power = .80

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Page 14: Statistical Power

MOBILE HEALTH STUDY

1. Choose test

Here, we will be using an

omnibus F test of a one-

way ANOVA with 3 levels

(or groups)

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Page 15: Statistical Power

MOBILE HEALTH STUDY

G*Power offers plenty of

tests

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Page 16: Statistical Power

MOBILE HEALTH STUDY

2. Determine the effect size

Means and standard deviations are guided by our hypotheses and previous research

SD = 3

Means:G1= 12,

G2 = 13, & G3 = 15*change power and group size

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Page 17: Statistical Power

MOBILE HEALTH STUDY

3. Calculate estimates

Our results:

To achieve a power of .80 and given the parameter estimates,

We will need at least 60 patients (20 per group) in the study

*note effect size

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Page 18: Statistical Power

MOBILE HEALTH STUDY

Alternatively, you can

manually enter the effect

size.

Again, guided by

hypotheses and previous

research

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Page 19: Statistical Power

A NOTE ON PRACTICALITY

That last test (with ES = .20) calls for a total sample size of 246 patients.

What if that’s not feasible?

You can:

Revisit your study design

Revise hypotheses, attempt other tests, change measures, etc.

Or, work backwards. Estimate power from a sample size that is practical

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Page 20: Statistical Power

REFERENCES

Howell, D., C. (2013). Power. In J. D. Hage (Ed.).

Statistical methods for psychology (8th ed., pp. 229-

249). Belmont, CA: Wadsworth, Cengage Learning.

Kraemer, H. C., Thiemann, S. (1987). How many

subjects? Newbury Park, CA: Sage Publications, Inc.

Lipsey, M. W. (1990). Design sensitivity: Statistcal

power or experimental research. Newbury Park, CA:

Sage Publications, Inc.

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Page 21: Statistical Power

BIG THANKS

To Dr. Philippe Gaillard for his wonderful guidance (and books!)

Also to the STAT 7970 class - wonderful audience.

To contact me

email - [email protected]

visit - http://cdatubo.weebly.com/

connect - http://www.linkedin.com/in/cdatubo

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