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www.elsevier.com/locate/schres
Schizophrenia Research
Associations of symptoms, psychosocial function and hope
with qualities of self-experience in schizophrenia: Comparisons
of objective and subjective indicators of health
Paul H. Lysaker a,b,*, Kelly D. Buck a, Kristin Hammoud a,
Amanda C. Taylor c, David Roe d
a Roudebush VA Medical Center, Day Hospital 116H, 1481 West 10th St, Roudebush VA Medical Center, Indianapolis, IN 46202, USAb Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, United States
c Indiana University Purdue University at Indianapolis, Dept of Psychology, Indianapolis, IN, United Statesd Institute for Health, Health Care Policy, and Aging Research, Rutgers University, NJ, United States
Received 9 September 2005; received in revised form 28 November 2005; accepted 7 December 2005
Available online 25 January 2006
Abstract
While changes in self-experience have been suggested to be an important element of recovery from severe mental illness,
little is known about how qualities of self-experience are linked with other indicators of health including objective measures
such as symptoms profiles and subjective measures such as hope. To examine these issues the narratives of self and illness of 65
persons with schizophrenia spectrum disorder were obtained prior to entry into rehabilitation and rated using the Scale to Assess
Narrative Development (STAND). STAND scores were then compared with concurrent assessments of hope assessed with the
Beck Hopelessness Scale (BHS), psychosocial function using the Quality of Life Scale (QOLS) and symptom profile defined
categorically using the Positive and Negative Syndrome Scale (PANSS). Results suggest that higher ratings of the STAND were
associated with greater expectations of perseverance on the BHS and higher levels of psychosocial function on the QOL. Lower
symptom profiles were similarly linked with higher STAND scores. Results suggest qualities of self-experience expressed
within personal narratives are linked to symptom profiles and subjective assessments of health. Theoretical and clinical
implications are discussed.
D 2005 Published by Elsevier B.V.
Keywords: Schizophrenia; Recovery; Symptoms; Narrative; Remission
0920-9964/$ - see front matter D 2005 Published by Elsevier B.V.
doi:10.1016/j.schres.2005.12.844
* Corresponding author. Roudebush VA Medical Center, Day
Hospital 116H, 1481 West 10th St, Roudebush VA Medical Center,
Indianapolis, IN 46202, USA.
E-mail address: [email protected] (P.H. Lysaker).
Conceptualizations of treatment outcome in schizo-
phrenia spectrum disorder have changed significantly
over the last 30 years. Initially, with a view of
schizophrenia as a condition characterized by steady
decline or persistent dysfunction, the aim of many
82 (2006) 241–249
P.H. Lysaker et al. / Schizophrenia Research 82 (2006) 241–249242
interventions was stability, or the absence of events
that might suggest further deterioration such as
symptom exacerbation, hospitalization, incarceration
or homelessness. As accumulating evidence has
suggested that a declining course is an exception
rather than a rule in schizophrenia (e.g. Harding et al.,
1992; Hoffman and Kupper, 2002) treatments have
expanded their targeted outcomes to include the
achievement of personally defined goals (Gingerich
and Mueser, 2005). Accordingly, stability has been
replaced as an outcome with the achievement of
health across multiple domains of recovery (Anthony,
1993; Corrigan, 2003; Liberman et al., 2002; Spaniol
et al., 2002; Roe, 2001; Whitehorn et al., 2002). As
summarized by Resnick et al. (2004), these domains
of recovery can be grouped into two different se7ts of
phenomena. The first involves objective assessments
of the absence of features of illness (e.g. the absence
of significant symptoms and adequate social and
vocational functioning). The second category is more
subjective and involves attitudes and life orientation
(e.g. the absence of significant symptoms and
adequate social and vocational functioning) and the
second category being more subjective and involving
attitudes and life orientation (e.g. hopefulness for a
good life ahead). Resnick and colleagues present data
from a large study which supports this conceptuali-
zation and suggest that symptoms, life satisfaction and
recovery orientation are related.
In addition to changes in life attitudes and orienta-
tion, two elements of the subjective domain of recovery
noted by Resnick et al. (2004) recovery for some may
also include changes in the qualities of self-experience
(Davidson, 2003; Lysaker and Lysaker, 2002;Williams
and Collins, 1999). Schizophrenia has been widely
characterized as involving fundamental alterations in
sense of self (Bleuler, 1911/1950; Roe and Davidson,
2005; Searles 1965; Stenghellini, 2004). It has been
suggested, for instance, that persons with schizophre-
nia experience a diminished sense of their lives as a
series of comprehensible events (Gallagher, 2003;
Holma and Aaltonen, 1997; Lysaker and Lysaker,
2002; Young and Ensign, 1999) and that they may
cease evolving an understanding of themselves as
meaningfully connected to others (Lysaker et al., 2003;
Roe et al., 2004). They may have trouble seeing
themselves as beings more than the sum of their
disorder (Roe and Ben-Yishai, 1999).
Given such alterations in self-experience it seems
logical that the subjective domain of recovery
described by Resnick and colleagues could include
changes in the qualities of self-experience including
the rediscovery of a sense of self as meaningfully
participating in life (Davidson, 2003; Lysaker and
Lysaker, 2002; Roe, 2005; Williams and Collins,
1999). This would be consistent with observations
that changes in self-experience may result from
improved function (Bebout and Harris, 1995; Roe,
2003) and/or that changes in persons’ experience of
themselves may facilitate changes in other domains of
function (Davidson, 2003; Lysaker et al., 2003; Roe,
2001). It is also consistent with recent qualitative
research (Jacobson, 2002; Roe and Chopra, 2003),
clinical reports (Lysaker and Buck, in press) and first
person accounts (Ridgway, 2001) which indicate that
as some experience wellness, they begin to express a
sense of themselves as able to affect the world and as
possessing social value.
Yet little is known about whether qualities of self-
experience in schizophrenia are related to other
indicators of health. Are they related to phenomenon
such as symptom profile, psychosocial function and
hopefulness? To date, one barrier to examining how
self-experience relates to other aspects that are
indicators of health is that most of the research on
self-experience in schizophrenia has been qualitative
(Davidson and Strauss, 1992; Lally, 1989; Roe and
Ben-Yishai, 1999) and thus not easily used to confirm
or disconfirm relationships with objective measures.
To address this problem, we have used a narrative
theory of self which stresses that sense of self can vary
from more to less coherent according to how it is
constituted within the stories one tells oneself and
others (Gallagher, 2000) to develop a semi-structured
interview and a scale to rate self-experience as
revealed in that interview. The interview, the Indiana
Psychiatric Illness Interview (IPII; Lysaker et al.,
2002), differs from other interviews in that it does not
directly pose beliefs for the participant to endorse or
decline but rather offers a forum for participants to
give voice to their own stories of themselves and their
challenges. The Scale to Assessment Narrative De-
velopment (STAND; Lysaker et al., 2003), which can
be used to rate the quality of a self-experience as
articulated within a narrative, provides an overall
index score and four subscales which separately
P.H. Lysaker et al. / Schizophrenia Research 82 (2006) 241–249 243
assess coherent experiences of deficits/challenges,
closeness with others; social value and an experience
of self as an active agent in life.
In the current study, we have rated narrative
interviews of participants with schizophrenia spec-
trum disorders using the STAND and compared those
ratings with concurrent assessments of symptoms,
awareness of illness, psychosocial function and self-
reported expectations of self-persistence. We reasoned
that if self-experience is related to other indicators of
health, then STAND scores would be correlated with
greater psychosocial function, hope and awareness of
illness. We similarly reasoned that participants with-
out significant levels of positive, negative and
cognitive symptoms using recently developed remis-
sion criterion (Andreasen et al., 2005) would have
higher overall STAND scores. To rule out the
possibility that the STAND merely assesses verbal
ability, we included a measure of verbal intelligence.
Lastly, we planned to examine associations of the
individual STAND scales with each of these other
measures for exploratory purposes. Of note, the
sample studied here includes persons willing to
engage in vocational rehabilitation. While this sample
may not generalize to all persons with schizophrenia,
we believed that this was a reasonable group to begin
to study given that as a group of persons with
significant deficits seeking to move towards recovery,
they are likely to be representative of many seeking
rehabilitation. Further, as a group perhaps midway
along a continuum of health, this group might display
a wide range of scores for our key variables allowing
for associations between variables to be meaningfully
studied.
1. Method
1.1. Participants
Participants were 64 adult men and one woman
with DSM-IV diagnoses of schizophrenia (n =40) or
schizoaffective disorder (n =25). These participants
comprised the full sample of persons enrolled in a
larger study seeking to develop a cognitive behavioral
therapy targeting working function in schizophrenia.
All were initially recruited from the outpatient
Psychiatry Service of a VA Medical Center and were
in a post acute phase of illness as defined by having
no hospitalizations or changes in medication or
housing in the month prior to entering the study.
Excluded from the study were participants with
mental retardation. Active substance use was also an
exclusion criterion as it was reasoned to affect
performance on all measures. The mean age and
education of the sample was 47.7 (sd=6.8) and 12.2
(sd=1.4) years respectively. Participants had, on
average, 9.9 lifetime psychiatric hospitalizations
(sd=7.0) with the first occurring on average at the
age of 24.2 (sd=6.1).
1.2. Instruments
Positive and Negative Syndrome Scale: (PANSS;
Kay et al., 1987) is a 30 item rating scale completed
by clinically trained research staff at the conclusion
of the chart review and semi-structured interview.
Individual items are rated on a b1Q to b7Q scale with
higher scores reflecting greater psychopathology.
Previous assessment of inter-rater reliability for this
study using the intraclass correlation found good to
excellent intraclass correlations on all scale scores
and most items (35). To determine the absence or
presence of significant levels of Positive, Negative
and Cognitive symptoms we used criteria recently
proposed by Andreasen et al. (2005), in collabora-
tion with other international groups, as a definition
of symptom remission or absence using the PANSS.
This scheme suggests scores of mild or less (b3Q) onthe Hallucinations, Delusions and Unusual Thoughts
items of the PANSS connote the absence of
significant positive symptoms, that scores of mild
or less on the Conceptual Disorganization and
Mannerisms items connote non-significant levels of
Cognitive symptoms and that scores of mild or less
on Social Withdrawal, Blunted Affect and Lack of
Spontaneity connote the absence of significant
negative symptoms. The absence of overall signif-
icant symptomatology is then defined as a state in
which all of these symptoms are present at a level
of mild or less. This scheme may be the most
parsimonious account to date because it contains the
smallest number of items, and items with the
smallest possible conceptual overlap. Items were
rated as they occurred over the 30 days prior to the
interview.
P.H. Lysaker et al. / Schizophrenia Research 82 (2006) 241–249244
Scale to Assess Unawareness of Illness (SUMD;
Amador et al., 1994) is a rating scale completed by
clinically trained research staff following a semi-
structured interview and chart review. For the
purposes of this study, we used the sum of the three
central items of the SUMD: a) awareness of mental
disorder; b) awareness of the consequences of mental
disorder; and c) awareness of the effects of medica-
tion. Each of these items is rated on a five point scale
which ranges from b1Q (complete awareness) to b5Q(severe unawareness). The total score can accordingly
range from 3 to 15. Assessment of inter-rater
reliability for raters in this study was in the good to
excellent range (intraclass r =.90).
The Vocabulary subtest (VS; Wechsler, 1997) is a
subtest of the WAIS III that assesses participants’
knowledge of vocabulary by presenting words for
participants to define in increasing order of difficulty.
This subtest has been widely used to assess global
verbal intellectual function. Age corrected scaled
scores are generated where the expected population
mean is a 10.
Beck Hopelessness Scale: (BHS, Beck et al., 1974)
is a questionnaire that asks participants to endorse
statements as true or false as applied to them.
Individual items are then summed. In this study we
used the scale score for motivational hope (MH), or
expectations of whether one will make an effort to
influence one’s life. Examples of items in the
motivational scale includes: bI might as well give up
because I can’t make things better for myself.Q Thisscale has been used successfully with a wide range of
psychiatric populations in the past and its validity and
reliability are reported elsewhere. In a previous
account we have reported that this scale of the BHS
may be uniquely linked with prospective performance
in rehabilitation (Davis et al., 2004). Scores on this
scale range from 0 to 8.
Quality of Life Scale (QOL; Heinrichs et al., 1984)
is a 21-item scale completed by clinically trained
research staff following a semi-structured interview
and chart review. For the purposes of this study, we
were interested in the sum of three of the four factor
scores of the QOL. The first, bInterpersonal relations,Qmeasures the frequency of recent social contacts and
includes separate assessments, for example, of fre-
quency of contacts with friends and acquaintances.
The second, bIntrapsychic foundations,Q measures
qualitative aspects of interpersonal relationships and
includes assessments, for example, of empathy for
others. The third, bCommon objects,Q reflects com-
munity participation and includes assessment of
participation in common community activities. Good
to excellent inter-rater reliability was found for the
QOL factor scores for this study, with intraclass
correlations ranging from .88 to .93. The fourth scale,
bInstrumental Function,Q assesses work function and
since all participants were entering vocational reha-
bilitation it was deemed irrelevant. Using these three
scales scores can range from 0 to 102.
Indiana Psychiatric Illness Interview (Lysaker et
al., 2002) is the semi-structured interview developed
to assess illness narratives. A research assistant
conducts the interview which typically lasts between
30 and 60 min. Responses are audiotaped and later
transcribed. The interview is divided conceptually
into four sections. First, rapport is established and
participants are asked to tell the story of their lives in
as much detail as they can. Second, participants are
asked if they think they have a mental illness and how
they understand it. This is followed up with a
question about what has and has not been affected
by their condition in terms of interpersonal and
psychological life. In the third section participants
are asked whether and, if so, how their condition
bcontrolsQ their life and how they bcontrolQ their
condition. Fourth, participants are asked what they
expect to stay the same and what will be different in
the future, again in terms of interpersonal and
psychological function. This measure differs from
other psychiatric interviews in that it does not
introduce content. If the participant does not mention
hallucinations, the IPII interviewer does not inquire
about hallucinations. The interviewer may ask for
clarification when confused and may query non-
directively. The tone of the interview is directed to be
conversational and questions are not posed for
participants to solve. The interviewer’s task is to
elicit enough information to understand the story a
participant is telling, not to confirm or refute. The IPII
thus results in a narrative of self and illness that can
be analyzed in terms of the gestalt or larger story
being told and not merely the presence or absence of
specific beliefs.
The Scale to Assess Narrative Development
(STAND; Lysaker et al., 2003) was designed to assess
P.H. Lysaker et al. / Schizophrenia Research 82 (2006) 241–249 245
four key aspects of recovery as they might emerge in
client narratives. It is composed of four subscales;
Social Worth, Social Alienation, Personal Agency
and Illness Conception, each rated on a 5-point likert
scale. Social Worth assesses the extent to which
persons experience themselves as valuable to others
and society. Social Alienation refers to the extent to
which persons experience intimate connections to
others in their families or communities. Personal
Agency assesses the degree to which persons
experience themselves as able to affect events in
their own lives. Lastly, Illness Conception assesses
the extent to which persons experience and can
account coherently for aspects of their disorder.
Subscale scores range from one to five and summing
all four subscale scores derives the STAND total
score. The anchors for each subscale have been
presented elsewhere (Lysaker et al., 2003) along with
evidence of an acceptable degree of internal consis-
tency (coefficient alpha= .86) and inter-rater reliabil-
ity for the total score (intraclass correlation= .87). A
later study with a different sample of participants
demonstrated persons with schizophrenia produced
significantly more impoverished narratives than
participants with other disabilities, such as, major
depression without psychosis or legal blindness
(Lysaker et al., 2005c). A third study with another
sample found evidence that greater STAND total
scores were linked to higher self-esteem and
readiness for change (Lysaker et al., in press). For
the current study, three raters achieved a significant
degree of inter-rater reliability (intraclass correla-
tion= .88) using 10 transcripts. Overall scores also
demonstrated a significant degree of internal consis-
tency (Cronbach’s alpha= .71) with no scale ob-
served to detract from the overall level of
consistency. With each scale ranging from 1 to 5,
the total score can range from 4 to 20.
Table 1
Spearman’s Rho correlations of STAND scores with insight, psychosocial
Illness awareness A
WAIS III vocabulary .22
SUMD total score � .50*** �Quality of life total scorea .31*
Beck hopelessness motivation scale .00
*p b .05; **p b .01; ***p b .001.a Total did not include the instrument function scale since all participan
1.3. Procedures
Following informed written consent, diagnoses
were determined using the Structured Clinical Inter-
view for the DSM IV (SCID; 42). The SCID was
conducted by a clinical psychologist. Next, partic-
ipants were given the PANSS, SUMD, VS, BHS,
QOL, and IPII as part of a baseline assessment for a
study of Cognitive Behavior Therapy and work
outcome. The IPII and PANSS interviews were
conducted by different personnel. The IPII interview
was audiotaped and later transcribed with identifying
information removed. Ratings of the transcripts were
made using the STAND with raters blind to partici-
pant identity, test performance, and symptom ratings.
Raters were not present during the PANSS, SUMD or
IPII interviews, nor did they transcribe the audiotapes
of the interviews. Raters had a minimum of a graduate
degree in psychology or nursing and were trained by
the first author. A subset of these IPII transcripts were
previously rated for levels of metacognition and
temporal connections within narratives using different
procedures and different raters and has been published
elsewhere (Lysaker et al., 2005a,b).
2. Results
Mean and standard deviations of PANSS scores for the
selected items were: Hallucinations 2.64 (1.55), Delusions
3.58 (1.36); Unusual Thoughts 2.62 (1.20); Conceptual
Disorganization 2.71 (1.31); Mannerisms 2.68 (.92); Social
Withdrawal 3.42 (1.12); Blunted Affect 3.35 (.89); and Lack
of Spontaneity 2.15 (1.23). Mean and Standard Deviations
of STAND scores were as follows: Illness awareness 3.67
(1.23); Alienation 2.80 (1.31); Agency 3.57 (1.39); Social
Worth 2.92 (1.14); Total 12.94 (3.75). Mean and standard
deviations for other outcome variables were: Vocabulary
9.61 (2.91), QOL total 47.87 (11.91), BHS Motivation scale
6.01 (2.47), and SUMD total 7.84 (2.50). STAND scores
function and expectations of persistence
lienation Agency Social worth Total
.15 .01 � .01 .10
.13 � .07 � .23 � .34**
.34** .40*** .20 .41***
.29* .36** .14 .28*
ts were unemployed and entering vocational rehabilitation.
P.H. Lysaker et al. / Schizophrenia Research 82 (2006) 241–249246
were not significantly correlated with age, education, or
lifetime number of hospitalizations. STAND scores did not
differ between participants with schizophrenia vs. schizo-
affective disorder. Intercorrelations among STAND sub-
scales ranged from .22 (Alienation and Social Worth) to .49
(Agency and Social Worth). Twenty three participants met
criteria for non-significant positive symptom profiles, 43 for
non-significant cognitive symptom profiles, 18 for non-
significant negative symptom profiles and 6 for non-
significant overall symptom profiles.
To compare associations of the STAND with the
Weschler Vocabulary subtest, SUMD total score, QOL total
score and BHS Motivation scale, Spearman Rho correlations
were calculated. This nonparametric correlation was chosen
because the BHS and QOL scores were not normally
distributed. As revealed in Table 1, the Weschler Vocabulary
subtest was unrelated to STAND scores while Higher QOL,
BHS Motivation and SUMD overall awareness of illness
were all associated with higher STAND total scores. Given
multiple significant univariate correlations, a stepwise
multiple regression was conducted in which the QOL,
SUMD and BHS scores were allowed to enter to predict the
STAND total score. This produced a significant predictor
equation ( f(2,61)=8.94, p b .001) with the QOL and SUMD
total making significant ( p b .05) unique contributions
respectively accounting for 17% and 6% of the variance
of the STAND total (total R2= .23).
To determine the relation of STAND scores to symptom
dimensions, ANOVA were performed comparing the
STAND scores among participants with significant vs non-
significant positive, negative, cognitive and overall symp-
tom profiles. As summarized in Table 2, significant differ-
ences were found on STAND scores for participants with
Table 2
ANOVA comparing STAND scores among participants with significant a
Illness awareness Alien
Positive symptom profiles
Non-significant (n =23) 4.13 (1.14) 3.04
Significant (n =42) 3.44 (1.24) 2.70
F 4.86* 1.01
Disorganized symptom profiles
Non-significant symptoms (n =43) 3.93 (1.21) 2.87
Significant symptoms (n =22) 3.20 (1.17) 2.70
F 5.30* .18
Overall symptoms
Non-significant symptoms (n =6) 4.33 (1.63) 4.12
Significant symptoms (n =59) 3.42 (1.12) 2.69
F 1.83 7.85*
*p b .05; **p b .01.
significant vs non-significant Positive, Cognitive and
Overall symptom profiles. No significant differences were
found on STAND scales for the significant vs. non-
significant Negative symptom profile group. Finally, a
discriminant function analysis was performed in which the
four individual STAND scale scores were allowed to enter
to predict membership in the significant vs non-significant
overall symptom profile groups. This produced a significant
overall correct classification rate of 74% (v2=9.62, p b .05)with 4 of the 6 (67%) participants without significant
symptoms correctly classified and 44 of 59 (75%) partic-
ipants with significant symptoms correctly classified.
3. Discussion
While the qualities of self-experience have been
hypothesized as an element of recovery, this is the first
study we are aware of to compare quantitative
assessments of self-experience with other clinical
and social indicators of wellness. Results suggest
there is significant overlap between more objective
outcomes and a quantitative assessment of self-
experience in schizophrenia. Persons rated as having
higher levels of psychosocial function tended to
construct narratives in which there was greater
articulation of personal difficulties coupled with a
greater experience of agency and intimate connection
with others. Persons who reported greater expect-
ations that they would persevere expressed in their
narratives more agency and connection to others. The
absence of significant positive symptoms was associ-
nd non-significant PANSS symptom profiles
ation Agency Social worth Total
(1.49) 4.13 (1.39) 3.09 (1.20) 14.39 (4.09)
(1.18) 3.27 (1.32) 2.85 (1.11) 12.23 (3.34)
6.00* .67 5.25*
(1.35) 3.89 (1.30) 3.17 (1.09) 13.73 (3.61)
(1.21) 3.14 (1.52) 2.45 (1.11) 11.56 (3.65)
3.41 6.26* 5.19*
(1.32) 4.83 (.40) 3.50 (.83) 16.83 (3.31)
(1.22) 3.49 (1.40) 2.87 (1.15) 12.61 (3.39)
* 5.70* 1.66 7.65**
P.H. Lysaker et al. / Schizophrenia Research 82 (2006) 241–249 247
ated with narratives in which persons better articulated
their difficulties and challenges and tended to expe-
rience themselves as able to affect the course of events
in their lives. The absence of significant cognitive
symptoms was also linked with more articulate
presentations of psychiatric difficulties and challenges
and the experience of a greater sense of worth within
one’s community. The absence of any significant
symptom was correlated with a greater experience of
agency and more intimate ties to others.
While the correlational nature of this study pre-
cludes the drawing of any causal connections, results
may suggest some hypotheses for future research.
Regarding subjective aspects of health and recovery, it
is possible that fuller self-experience is necessary for
the development of social relations or that one must
have hope and social connection for a fuller self-
experience. It is additionally possible that both exert a
mutual influence over one another (Roe, 2005).
Additionally, it may be that cognitive symptoms make
it especially difficult to see oneself valued in the eyes of
others. Certainly this is intuitively consistent with
observations that the ability to meaningfully link ideas
together could be essential for any complex self
narrative to be constructed in an ongoing manner
(Lysaker and Lysaker, 2002). Results could also be
interpreted as suggesting that the presence of a
significant positive symptom profile represents a
particular barrier to persons seeking to see themselves
as active agents in the world. Again it seems a matter of
intuition that intrusive hallucinations which occur
beyond one’s control as well as a sense of oneself as
perpetually in danger could interfere with the construc-
tion of a sense of self as able. It is also possible that with
greater decrements in self-experience, persons are also
more vulnerable to symptoms. Importantly, these
speculations await future longitudinal research, and
there aremany rival hypotheses that cannot be ruled out.
Indeed, consistent with models of how cognitive
therapy helps reduce positive symptoms (Haddock et
al., 1998), it is possible that as persons with schizo-
phrenia see themselves as more capable and able to
cope, it becomes easier to manage positive symptoms
and consequently the severity of those symptoms
decreases. It is also possible all relationships observed
with the STANDweremediated by factors not assessed.
While this was largely an exploratory study there
were some surprising findings. The STAND scores of
participants with significant vs. not significant nega-
tive symptom profiles did not differ significantly. This
may reflect, as noted by Andreasen and colleagues
(2005), that negative symptoms can result from many
different sources. For example, negative symptoms
may be linked to cognitive dysfunction (e.g. Bryson et
al., 1997), or, as suggested by Corin (1998), with-
drawal for some may be a means to establish a more
solid identity or help a person manage particularly
difficult periods (Strauss et al., 1989). Thus, perhaps
for some, negative symptoms may hamper narrative
development while for others it may be paradoxically
helpful, resulting in no single pattern of association
with narrative qualities. We were also surprised that
while illness awareness was linked to a traditional
measure of insight, no other STAND scale was linked
to this measure. This may suggest insight assessed
through direct interviews may tap related but different
phenomena than what is assessed when persons are
given a larger forum to articulate their views. This
finding is consistent with the conceptualization of
insight as including descriptive facts that could be
differentiated from narrative facts in terms of the kind
of information each intended to communicate. It has
been argued (Roe and Kravetz, 2003) that descriptive
facts may serve essentially to provide a reliable
account of states of affairs while narrative facts may
represent attempts to communicate the specific
emotional experiences associated with a series of
events and to gain control over these events by
transforming them into a story. Again as with all
unexpected findings these thoughts are preliminary
and await replication before they should be given any
weight.
There are also limitations to this study. Sample size
was modest in relation to the number of comparisons
made. Although we utilized more conservative two
tailed tests, and despite unidirectional hypotheses, risk
of spurious findings was increased. Generalization of
findings also is limited by sample composition.
Participants were mostly males in their forties willing
to enter rehabilitation. They were thus a group in
some sense healthier than some groups but perhaps
less healthy than others. They were willing to try
vocational rehabilitation and held success as a
possibility for themselves but, on the other hand, they
were not working and thus had much progress to
make in the vocational domain of recovery. It may
P.H. Lysaker et al. / Schizophrenia Research 82 (2006) 241–249248
well be that a different relationship exists between
symptom remission and narratives in schizophrenia
among females or among younger males with
schizophrenia, or persons who decline treatment or
who are working and not in need of vocational
rehabilitation. Additionally, symptoms were assessed
only over the course of one month while the
recommendation of Andreasen et al. (2005) is that
symptoms be assessed over six months. Finally, it is
unclear what symptom absence represents in this
sample. It could be that they may not have previously
had symptoms in that domain and thus we may be
more accurately assessing symptoms absence. Ac-
cordingly, future longitudinal studies of symptoms
and narrative constructs are planned with more diverse
groups of persons which address issues of recovery or
improvements from previously levels of function.
With replication, the STAND may come to have
clinical implications. STAND subscale scores may
serve to point to areas of need as persons move toward
wellness. For instance, the presence of lower illness
awareness scores may suggest a need for a treatment
which helps persons grasp the fuller meaning of their
deficits, while lower agency scores may suggest a
treatment which assists persons to focus on their
strengths and challenge beliefs regarding helplessness.
As illustrated in a recent case study (Lysaker and
Buck, in press) repeated assessments of counseling
transcripts using the STAND may also provide an
empirical assessment of progress and bring to
clinician’s attention areas that they might want to
inquire about further.
References
Amador, X.F., Flaum, M., Andreasen, N.C., Strauss, D.H., Yale,
S.A., Clark, S.C., Gorman, J.M., 1994. Awareness of illness in
schizophrenia and schizoaffective and mood disorders. Arch.
Gen. Psychiatry 51, 826–836.
Andreasen, N.C., Carpenter, W.T., Kane, J.M., Lasser, R.A.,
Marder, S.R., Weinberger, D.R., 2005. Remission in schizo-
phrenia: proposed criteria and rationale for consensus. Am. J.
Psychiatry 162, 441–449.
Anthony, W.A., 1993. Recovery from mental illness: the guiding
vision of the mental health service system in the 1990s.
Psychosoc. Rehabil. J. 16, 11–24.
Bebout, R.R., Harris, M., 1995. Personal myths about work and
mental illness: response to Lysaker and Bell. Psychiatry 58,
401–404.
Beck, A.T., Weisman, A., Lester, D., Trexler, L., 1974. The
measurement of pessimism: the hopelessness scale. J. Consult.
Clin. Psychol. 42, 861–865.
Bleuler, E., 1911/1950. Dementia Praecox or the Group of
Schizophrenias Translated by J. Zinkin. International Universi-
ties Press, New York.
Bryson, G.J., Bell, M.D., Lysaker, P.H., Greig, T., Kaplan, E.Z.,
1997. Affect recognition in schizophrenia: a function of global
impairment or a specific cognitive deficit? Psychiatry Res. 71,
105–113.
Corin, E., 1998. The thickness of being: intentional worlds,
strategies of identity and experience among schizophrenics.
Psychiatry 61, 133–147.
Corrigan, P.W., 2003. Toward an integrated structural model of
psychiatric rehabilitation. Psychiatr. Rehabil. J. 26, 346–358.
Davidson, L., 2003. Living Outside Mental Illness: Qualitative
Studies of Recovery in Schizophrenia. New York University
Press, New York.
Davidson, L., Strauss, J.S., 1992. Sense of self in recovery from
severe mental illness. Br. J. Med. Psychol. 65, 131–145.
Davis, L.D., Nees, M., Hunter, N., Lysaker, P.H., 2004. Hopeless-
ness as a predictor of work function in schizophrenia. Psychiatr.
Serv. 55, 434–436.
Gallagher, S., 2000. Philosophical conceptions of the self:
implications for cognitive science. Trends Cogn. Sci. 4,
14–21.
Gallagher, S., 2003. Self narrative in schizophrenia. In: Kirshner, T.,
David, A. (Eds.), The Self in Neuroscience and Neuropsychi-
atry. Cambridge University Press, UK, pp. 336–353.
Gingerich, S., Mueser, K.T., 2005. Illness management and
recovery. In: Drake, R., Merrens, M., Lynde, D. (Eds.),
Evidence-Based Mental Health Practice: A Textbook. WW
Norton, New York, pp. 395–424.
Haddock, G., Tarrier, N., Spaulding, W., Yusupoff, L., Kinney, C.,
McCarthy, E., 1998. Individual cognitive behavior therapy in
the treatment of hallucinations and delusions. Clin. Psychol.
Rev. 7, 821–838.
Harding, C.M., Zubin, J., Strauss, J., 1992. Chronicity in
schizophrenia. Br. J. Psychiatry 161 (supp 18), 27–37.
Heinrichs, D.W., Hanlon, T.E., Carpenter, W.T., 1984. The quality
of life scale: an instrument for assessing the schizophrenic
deficit syndrome. Schizophr. Bull. 10, 388–396.
Hoffman, H., Kupper, Z., 2002. Facilitators of psychosocial
recovery from schizophrenia. Int. Rev. Psychiatry 14, 293–302.
Holma, J., Aaltonen, J., 1997. The sense of agency and the search
for narrative in acute psychosis. Contemp. Fam. Ther. 19,
463–477.
Jacobson, N., 2002. Experiencing recovery: a dimensional analysis
of recovery narratives. Psychiatr. Rehabil. J. 24, 248–254.
Kay, S.R., Fizszbein, A., Opler, L.A., 1987. The positive and
negative syndrome scale for schizophrenia. Schizophr. Bull. 13,
261–276.
Lally, S.J., 1989. Does being here mean there is something wrong
with me? Schizophr. Bull. 15, 253–265.
Liberman, R.P., Kopelowicz, A., Ventura, J., Gutkind, D., 2002.
Operational criterial and factors related to recovery from
schizophrenia. Int. Rev. Psychiatry 14, 256–272.
P.H. Lysaker et al. / Schizophrenia Research 82 (2006) 241–249 249
Lysaker, P.H., Buck, K.D., in press. Psychotherapeutic dialogue and
schizophrenia: movements towards recovery within client’s
personal narratives. J. Psychosoc. Nurs. Ment. Health Serv.
Lysaker, P.H., Lysaker, J.T., 2002. Narrative structure in psychosis:
schizophrenia and disruptions in the dialogical self. Theory
Psychol. 12, 207–220.
Lysaker, P.H., Clements, C.A., Plascak-Hallberg, C.D., Knipscheer,
S.J., Wright, D.E., 2002. Insight and personal narratives of
illness in schizophrenia. Psychiatry 65, 197–206.
Lysaker, P.H., Wickett, A.M., Campbell, K., Buck, K., 2003.
Movement toward coherence in the psychotherapy of schizo-
phrenia: a method for assessing narrative transformation. J. of
Nerv. Ment. Dis. 191, 538–541.
Lysaker, P.H., Carcione, A., Dimaggio, G., Johannesen, J.K.,
Nicolo, G., Procacci, M., Semerari, A., 2005a. Metacognition
amidst narratives of self and illness in schizophrenia: associa-
tions with insight, neurocognition, symptom and function. Acta
Psychiatr. Scand. 112, 64–71.
Lysaker, P.H., France, C.M., Davis, L.W., Hunter, N., 2005b.
Personal narratives of illness in schizophrenia: associations with
neurocognition and symptoms. Psychiatry 68, 140–151.
Lysaker, P.H., Wickett, A.M., Davis, L.W., 2005c. Narrative
qualities in schizophrenia: associations with impairments in
neurocognition and negative symptoms. J. of Nerv. Ment. Dis.
193, 244–249.
Lysaker, P.H., Taylor, A.C., Miller, A., Beatte, N.E., Strasburger,
A.S., Davis, L.W., In press. The scale to assess narrative
development: associations with other measures of self and
readiness for recovery in schizophrenia spectrum disorders. J. of
Nerv. Ment. Dis.
Resnick, S.G., Rosenheck, R.A., Lehman, A.F., 2004. An explor-
atory analysis of correlates of recovery. Psychiatr. Serv. 55,
540–547.
Ridgway, P., 2001. Restoring psychiatric disability: learning from
first person recovery narratives. Psychiatr. Rehabil. J. 24,
335–343.
Roe, D., 2001. Progressing from bpatienthoodQ to bpersonhoodQacross the multi-dimensional outcomes in schizophrenia and
related disorders. J. of Nerv. Ment. Dis. 189 (10), 691–699.
Roe, D., 2003. A prospective study on the relationship between self-
esteem and functioning during the first year after being
hospitalized for psychosis. J. of Nerv. Ment. Dis. 191, 45–49.
Roe, D., 2005. Recovering from severe mental illness: mutual
influences of self and illness. J. Psychosoc. Nurs. Ment. Health
Serv. 43 (12), 35–40.
Roe, D., Ben-Yishai, A., 1999. Exploring the relationship between
the person and the disorder among individuals hospitalized for
psychosis. Psychiatry 62, 370–380.
Roe, D., Chopra, M., 2003. Beyond coping with mental illness:
towards personal growth. Am. J. Orthopsychiatr. 73 (3),
334–344.
Roe, D., Davidson, L., 2005. Self and narrative in schizophrenia:
time to author a new story. J. Med. Humanit. 31, 89–94.
Roe, D., Kravetz, S., 2003. Different ways of being aware of a
psychiatric disability: a multifunctional narrative approach to
insight into mental disorder. J. of Nerv. Ment. Dis. 191,
417–424.
Roe, D., Chopra, M., Rudnik, A., 2004. Coping with mental illness:
people as active agents interacting with the disorder. Psychiatr.
Rehabil. J. 28, 122–128.
Searles, H., 1965. Collected Papers of Schizophrenia and Related
Subjects. International Universities Press, New York.
Spaniol, L., Wewiorsky, N.J., Gagne, C., Anthony, W., 2002. The
process of recovery from schizophrenia. Int. Rev. Psychiatry 14,
327–336.
Stenghellini, G., 2004. Disembodied Spirits and Deanimated
Bodies: the Psychopathology of Common Sense. Oxford
University Press, NY NY.
Strauss, J.S., Rakfeldt, J., Harding, C.M., Lieberman, P., 1989.
Psychological and social aspects of negative symptoms. Br. J.
Psychiatry 155 (Suppl. 7), 128–132.
Wechsler, D., 1997. Wechsler Adult Intelligence Scale — III.
Psychology Corporation, San Antonio, TX.
Whitehorn, D., Brown, J., Richard, J., Rui, Q., Kopla, L., 2002.
Multiple dimensions of recovery in early psychosis. Int. Rev.
Psychiatry 14, 273–293.
Williams, Collins, A.A., 1999. Defining new frameworks for
psychosocial interventions. Psychiatry 62, 61–78.
Young, S.L., Ensign, D.S., 1999. Exploring recovery from the
perspective of persons with psychiatric disabilities. Psychiatr.
Rehabil. J. 22, 219–231.