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Global Emerging Fungal Infection Registry Initiated in 2003 Report December 2014 Working group of the Under the auspices of Supported by unrestricted grants from Astellas Pharma, Gilead Sciences, Merck, and Pfizer

Report December 2014

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Global Emerging Fungal Infection Registry

Initiated in 2003

Report December 2014

Working group of the

Under the auspices of

Supported by unrestricted grants from

Astellas Pharma, Gilead Sciences, Merck, and Pfizer

TABLE OF CONTENTS

INTRODUCTION 3

CURRENT RESULTS 7

PUBLIC RELATION ACTIVITIES 13

FUNGIQUEST ACTIVITY 13

ACHIEVEMENTS AND GOALS 15

PRESENTATIONS 2012 - 2014 15

PUBLICATIONS 16

AWARDS 17

ACCOMPLISHMENTS 17

GOALS FOR 2015 17

CONTACT INFORMATION 18

STUDY COORDINATORS 19

ACTIVE PARTNERS 22

PARTNERS 29

Introduction

The incidence of invasive fungal disease (IFD) is increasing in all parts of the

world. The etiology for this ongoing epidemiological development is not

completely understood. However, major contributing factors are the increasing

number of transplantation procedures undertaken around the world (estimated

at 500,000 per year), a widening of the indications for intensive chemotherapy,

and the growing number of other clinical conditions requiring

immunosuppressive treatment.

Therapeutic standards have been developed for the most frequent IFD, i.e.

candidiasis, aspergillosis and cryptococcosis. However, the so called “emerging

fungi” are also a reason for the increased number of IFDs. Thus, clinicians are

now facing infections due to a variety of different fungi without any reliable

treatment recommendations and therapeutic decision making is not evidence-

based. Prevalence of “emerging fungi” is virtually unknown and there is an

additional knowledge gap in pathogen biology, since isolates have not been

collected systematically.

These shortcomings have been described in detail in the recent Clinical Practice

Guidelines of the European Fungal Infection Study Group (ESCMID-EFISG) and

the European Confederation of Medical Mycology (ECMM).

In order to help alleviate the lack of knowledge on epidemiology, clinical

course, biology and pathomechanisms, and finally to aid in facilitating an

evidence based diagnostic-therapeutic integrated approach of IFD caused by

“emerging fungi”, Fungiscope™ - A Global Emerging Fungal Infection Registry

has been created in 2003.

FungiScope™ uses a web-based electronic case form accessible via

www.fungiscope.net.

For inclusion into the registry cultural, histopathological, serological or

molecular evidence of IFD and associated clinical symptoms and signs are

required. The clinical data on underlying disorder and IFD are entered through

a web-based interface. Ideally, the pathogen isolated and samples of infected

tissue are collected, examined and stored in a bio-bank called Fungithek. The

clinical and biological data are subsequently evaluated and analysed. Figure 1a

and b present the data / sample flow and overall project structure. The clinical

database and the bio-bank are connected and anonymized data are easily

accessable via a web-based search engine - FungiQuest (Figure 2).

In the following report we introduce the most current results and

achievements. We also discuss future goals and ongoing developments of the

project.

Figure 1a. Project structure

Report December 2014 5

<

Figure 1b. Material flow. Fungal isolates can be send 1.) to Prof. Cornely to Cologne, Germany for formal identification and

biobanking in the FungiThek or 2.) to the reference lab in your country (please see in section Study Coordinators below).

Bottom: Reference analyses from biopsies will be performed at the Robert Koch Institute in Berlin, Germany.

Results are

documented in the

database by the FungiScope.Team

Biopsy

Shipment to:

Prof. Cornely Cologne, GER

Sequencing and

Ribosomal RNA FISH

For

reference

analysis:

Isolate

FungiThek Isolate Collection

in Cologne

Morphological ID Sequencing & MALDI-TOF

1. Shipment to:

Prof. Cornely Cologne, GER

Research

Isolate Collection at central lab

2. Shipment to:

Central Lab in your country

Morphological ID

Sequencing & MALDI-TOF

& Labor Dr. Wisplinghoff

or

Report December 2014 6

Figure 2. FungiQuest database search engine

Found a fungus you know nothing about?

Go to www.fungiquest.net Type the name of the fungus

into the search box

Browse through FungiScope cases with

the same kind of fungal infection

Report December 2014 7

Current Results

Until now, 402 cases have been documented and considered valid. The most

frequently registered pathogens were mucoromycotina (n=177; 44%), Fusarium

spp. (n=63; 15.7%), yeasts (n=53; 13.2%), and Dematiaceae (n=44; 10.9%)

followed by Penicillium spp./Paecilomyces spp. (n=19; 4.7%) and Scedosporium

spp. (n=15; 3.7 %) (Figure 3). The contribution of cases by country is shown in

Figure 4. A list of major contributors is given in Figure 5, whereby the majority of

cases has been documented by central laboratories that have an intermediary

function between contributors from their country and FungiScope. The majority of

documented patients were Caucasian (70%) followed by Asian (23%) and

North/South American Indian origins (3%) (Figure 6).

Sites of infection differ among pathogens (Figure 7). In patients with invasive

mucormycosis, the lungs were the most commonly involved organs with an

incidence of 70.1%. Other involved sites were the paranasal sinuses (22.6%), deep

soft tissues (15.3%) and the central nervous system (13.6%). Fusarium spp.

infections most frequently presented as blood stream infections (47.6%) or skin

infections (46%). Other commonly affected sites were lungs (38.1%) and deep soft

tissues (22.2%). Infections with Dematiaceae mostly involved the paranasal

sinuses, eyes, deep soft tissues, lungs, and skin (range from 11.4% to 31.8%).

Yeasts were most often diagnosed from blood cultures (67.9%) followed by

pulmonary infections (26.4%).

The evaluation of risk factors for the development of IFD revealed differences

between individual pathogens shown in Figure 8. The most common risk factors for

developing an infection with Mucorales and Fusarium spp. were chemotherapy

(55.9% and 57.1%, respectively) or haematopoetic stem cell transplantation

(HSCT) (31.6% and 30.2%, respectively) followed by Intensive Care Unit (ICU) stay

and diabetes mellitus, with rates of 15.8% to 27.1%.

In patients presenting with yeast infections chemotherapy was also the most

common risk factor (50.9%). In addition, 37.7% of patients were treated in

intensive care units. Other risk factors were solid organ transplantation (11.3%),

diabetes mellitus and chronic pulmonary disease (each 13.2%), and haematopoetic

stem cell transplantation (18.9%).

By contrast, patients with a Dematiaceae infection presented most frequently with

diabetes mellitus (40.9%) and/or chronic renal disease (13.6%).

All-cause-mortality, mortality due to fungal infection and response to treatment

differed among individual pathogens and are shown in Figure 9. The highest all-

cause-mortality was observed in patients with mucoromycosis (59.3%), followed by

patients with yeast (54.7%) and Fusarium spp. infections (50.8%). When looking

at the mortality due to the fungal infection it was highest in infections caused by

Mucorales (45.2%) followed by Fusarium spp (38.1%) and Yeast (41.5%). By

contrast, the lowest all-cause-mortality was revealed in patients with Dematiaceae,

equaling only 9%. Just 5% of these deaths was due to the fungal infection. The

highest rates of complete and partial remissions were observed in patients with IFD

Report December 2014 8

caused by Dematiaceae and Penicillium/Paecilomyces spp (73.5% and 70.6%,

respectively). Patients with a Mucorales infection displayed the lowest rate of

response to treatment (39.9%).

In conclusion, the clinical relevance of invasive fungal infections by emerging fungi

is increasing. Over the past 10 years a large number of cases from several countries

world-wide could be documented and showed a broad spectrum of pathogens.

Further investigators and coordinators are encouraged to contribute to the success

of FungiScope™.

Figure 3. Distribution of 402 pathogens by major group

Figure 4. Contributing countries

177

63

53

44

1915 29

Mucorales

Fusarium

Yeast

Dematiaceae

Penicillium/Paecilomyces

Scedosporium

Others

Report December 2014 9

Figure 5. List of major contributors including three central laboratories in the

Czech Republic (Z. Racil), Russia (N. Klimko) and India (A. Kindo).

Figure 6. Distribution of major ethnic subgroups

70%

23%

3%1% 3%

CaucasianAsianAmerican Indian or Alaska NativeSub-Saharan African/Afro-AmericanOther

0%

5%

10%

15%

20%

Report December 2014 10

Figure 7. Sites of infection for major groups of fungi. (CNS, Central nervous system)

11%

11%

12%

14%

15%

23%

70%

Gastrointestinal tract

Skin

Bones

CNS

Deep soft tissues

Paranasal sinus(es)

Lungs

Mucorales (n=177)

16%

18%

22%

38%

46%

48%

Eyes

Paranasal sinus(es)

Deep soft tissues

Lungs

Skin

Blood

Fusarium (n=63)

13%

13%

15%

26%

68%

Kidneys

Liver

CNS

Lungs

Blood

Yeasts (n=53)

11%

14%

18%

25%

32%

Skin

Lungs

Deep soft tissues

Eyes

Paranasal sinus(es)

Dematiaceae (n=44)

Report December 2014 11

Figure 8. Most important risk factors for major groups of fungi. (HSCT, Hematopoietic stem cell transplantation; ICU,

Intensive Care Unit)

56%

32%

27%

16%

Chemotherapy

HSCT

ICU stay

Diabetes mellitus

Mucorales (n=177)

57%

30%

19%

18%

Chemotherapy

HSCT

ICU stay

Diabetes mellitus

Fusarium (n=63)

51%

37%

19%

13%

13%

11%

11%

Chemotherapy

ICU stay

HSCT

Chronic pulmonary disease

Diabetes mellitus

Chronic renal disease

Solid organ transplantation

Yeasts (n=53)

41%

14%

14%

11%

Diabetes mellitus

Chemotherapy

Chronic renal disease

Solid organ transplantation

Dematiaceae (n=44)

Report December 2014 12

Figure 9. Mortality rates and outcome for major groups of fungi. Favorable outcome is defined by complete response and

stable disease.

59%

45%

40%

51%

38%

49%

55%

42%

47%

9%5%

75%

Mortality Mortality due to IFD Favourable outcome

Mucorales Fusarium Yeasts Dematiaceae

Report December 2014 13

Public Relation Activities

We were pleased to present FungiScope® at ICAAC 2013 in Denver at a booth

in the exhibition hall. There we offered information about the project in

pamphlets as well as reminders of the activity (Fungiscope® pens and post-it

pads). Over the 3 days of the

convention, an estimated 100

conversations, either brief or

more in-depth, were held about

the project with interested booth

visitors. The majority of visitors,

who were mainly clinicians or

microbiologists, had never heard

of Fungiscope®, and many

commented that there is a

definite need for this registry and

were happy to realize that it

exists and could be a receptacle

for cases from their institution. Approximately 250 flyers were taken, along

with 500 pens and 250 post-it pads.

Karen Pankraz, TA from our team, was at the booth fulltime to welcome

inquiries and distribute information. Additionally, Dr. Wahlers, Dr. Vehreschild

and Prof. Cornely were often present to answer specific and in-depth questions

about the project. Where appropriate, contact information was collected for

future collaboration.

Overall, this was a positive experience for our team—many inquiries, much

positive feedback.

FungiQuest Activity

The usage of FungiQuest has been monitored continously over the last four

years and information of country of origin of users has been collected.

Figure 10 gives an overview over the number of enquieries on the website and

an overview of the countries the enquieries came from. Of note, the usage has

increased considerably since May 2013 i.e. after our ECCMID appreance.

Report December 2014 14

Figure 10. FungiQuest User. Left: Number of enquiries of FungiQuest per month (trendline is displayed as dashed

Right: Countries of origin of FungiQuest-Users (countries with >10 clicks are shown).

1 100

GermanyUnited States

ChinaNetherlands

FranceItaly

RomaniaRussia

CanadaSpain

TurkeyIndia

AustraliaJapan

SwedenArgentina

GreeceBelgium

PolandGreat Britain

AustriaUkraine

SwitzerlandBrazilCuba

DenmarkMalaysiaHungary

MexicoPortugal

Tunisia

Overall clicks

Report December 2014 15

Achievements and Goals

Presentations 2012 - 2014

October 13 – 15, 2014 Research for Rare - Translational Science Meeting,

Munich, Germany

September 5 – 9, 2014 54th Interscience Conference on Antimicrobial

Agents and Chemotherapy (ICAAC), Washington,

USA

June 25 – 28, 2014 Kongress für Infektionskrankheiten und

Tropenmedizin (KIT), Köln, Germany

June 15 – 16, 2014 Symposium on Infections in the

immunocompromised hosts, International

Immunocompromised Host Society (ICHS), Berlin,

Germany

May 10 – 13 , 2014 24th European Congress of Clinical Microbiology

and Infectious Diseases (ECCMID), Barcelona,

Spain

January 10 – 12, 2014 10th National Conference of the Society for Indian

Human and Animal Mycologists (SIHAM),

Coimbatore, Tamil Nadu, India

October 11 – 14, 2013 6th Trends in Medical Mycology (TIMM),

Copenhagen, Denmark

September 22 – 25, 2013 Joint Annual Meeting of the German Society for

Hygiene and Microbiology and the German Society

for Infectious Diseases (DGI), Rostock, Germany

September 9 – 13, 2013 53rd Interscience Conference on Antimicrobial

Agents and Chemotherapy (ICAAC), Denver, CO,

USA

September 5 – 7, 2013 47th Congress of the German Society for Mycology

(DMykG e.V.), Tübingen, Germany

April 27 – 30, 2013 23rd European Congress of Clinical Microbiology

and Infectious Diseases (ECCMID), Berlin,

Germany

October 19-23, 2012 Annual Congress of the German Society for

Hematology and Oncology (DGHO), Stuttgart,

Germany

September 9-12, 2012 52nd Interscience Conference on Antimicrobial

Agents and Chemotherapy (ICAAC), San

Francisco, CA, USA

June 23-26, 2012 18th Congress of the International Society for

Human and Animal Mycology, Berlin, Germany

Report December 2014 16

Publications

October 2013 Nucci M, Marr K, Vehreschild M, de Souza C, Velasco E,

Cappelano P, Carlesse F, Queiroz-Telles F, Sheppard D,

Kindo A, Cesaro S, Hamerschlak N, Solza C, Heinz W,

Schaller M, Atalla A, Arikan-Akdagli S, Bertz H, Castro Jr

C, Herbrecht R, Hoenigl M, Härter G, Hermansen NE,

Josting A, Pagano L, Salles M, Mossad SB, Ogunc D,

Pasqualotto A, Araujo V, Troke P, Lortholary O, Cornely O,

Anaissie E: Improvement in the outcome of invasive

fusariosis in the last decade. Accepted for publication in

Clinical Microbiology and Infection

May 2013 Pagano L, Cornely O, Caira M, Cesaro S, Gasbarrino C,

Girmenia C, Heinz WJ, Herbrecht R, Lass-Flörl C, Nosari A,

Potenza L, Racil Z, Rickerts V, Sheppard DC, Simon A,

Ullmann AJ, Valentini CG, Vehreschild JJ, Candoni A,

Vehreschild MJ. Combined antifungal approach for the

treatment of invasive mucormycosis in patients with

hematological diseases: a report from the SEIFEM and

FUNGISCOPE registries. Haematologica 2013 May 28,

Epub ahead of print

January 2013 Christopeit M, Lindner A, Surov A, Weber T, Vehreschild

MJ, Bialek R, Schmoll HJ.Right flank pain and high fever in

a neutropenic patient with acute lymphoblastic leukaemia.

Mycoses 2013, Jan; 56(1):90-92

October 2011 de Hoog GS, Robert V, Lackner M, Vehreschild MJ,

Vehreschild JJ, Symoens F, Göttlich-Fligg E, Garcia-

Hermoso D, Harun A, Meyer W, Chen SC, Hamprecht A,

Fischer G, Buzina W, Cornely OA, Guarro J, Cano J, Horré

R

Making moulds meet. Information retrieval as a basis for

understanding Pseudallescheria and Scedosporium

Mycoses. 2011 Oct;54 Suppl 3:1-4

December 2009 M.J.G.T. Rüping, W.J. Heinz, A.J. Kindo, V. Rickerts, C.

Lass-Flörl, C. Beisel, R. Herbrecht, Y. Roth, G. Silling, A.J.

Ullmann, K. Borchert, G. Egerer, J. Maertens, G.

Maschmeyer, A. Simon, M. Wattad, G. Fischer, J.J.

Vehreschild, O.A.Cornely Forty-one Recent Cases of

Invasive Zygomycosis from a Global Clinical Registry

J Antimicrob Chemother. 2010 Feb;65(2):296-302

July 2008 Rüping M.J.G.T., Albermann N., Ebinger F., Burckhard I.,

Beisel C., Müller C., Vehreschild J.J., Kochanek M.,

Report December 2014 17

Fätkenheuer G., Bangard C., Ullmann A.J., Herr W., Kolbe

K., Hallek M., Cornely O.A.

Posaconazole concentrations in the central nervous

system.

J Antimicrob Chemother 2008 Dec;62 (6):1468-70

Awards

Young Investigator Award 2010 (Nachwuchsförderpreis) of the German

Society for Mycology (DMykG e.V.) awarded to Dr. M.J.G.T. Vehreschild for

her work on FungiScope

Accomplishments

Booth in exhibit hall of 53rd Interscience Conference on Antimicrobial

Agents and Chemotherapy (ICAAC), Denver, CO, USA (September 9 –

13, 2013)

Database restructuring including:

o Harmonizing different wording used for documentation

o Implementation of new taxonomy

o Structural adjustments facilitating data export and analysis

o Incorporation of FungiThek into the database

Optimization of workflow for centralized reference analysis of fungal

isolates

New web presence on the Research for Rare website

www.research4rare.de

Goals for 2015

Launch of new CRF with renewed and approved votum of the ethics

committee

Extending the FungiQuest™ platform (launched in April 2010)

o Faster inclusion of new cases

o Inclusion of FungiThek / isolate information

o Improved search-engine cross linking old and new taxonomy

Publication of a subset analysis on rare yeasts, including resistance

patterns

Publication of a comparison between sequencing and morphological

results for the first 100 FungiScope isolates

Report December 2014 18

Contact Information

Chair

Oliver A. Cornely, MD, FIDSA, FACP

[email protected]

Project coordinator

Danila Seidel, PhD

[email protected]

Coordinating physicians

Maria J.G.T. Vehreschild (née Rüping), MD

[email protected]

Kerstin Wahlers, MD

[email protected]

Reviewing physicians

Philipp Köhler, MD

[email protected]

Hilmar Wisplinghoff, MD

[email protected]

Reviewing documentarist

Frank Mueller

[email protected]

Technical advisor, site operator clinicalsurveys.net

Jörg J. Vehreschild, MD

[email protected]

Universität zu Köln

Infectious Diseases – Clinical Trials Unit II

Zentrum für Klinische Studien (ZKS)

Herderstr. 52-54

50931 Köln

Germany

T +49-221-478-6494

F +49-221-478-3611

www.fungiscope.net

Report December 2014 19

Study Coordinators

Clinical ID Microbiology Molecular Biology Pharmacology Pathology

Austria

Elisabeth Presterl, MD

Allgemeines Krankenhaus -

Universitätskliniken Wien

Währinger Gürtel 18-20

1090 Wien

T +43-1-40400-4440

F +43-1-4400-4418

elisabeth.presterl@meduniwie

n.ac.at

Cornelia Lass-Flörl, MD

Institute of Hygiene,

Microbiology and Social

Medicine

Universität Innsbruck

Fritz-Pregl-Str. 3

6020 Innsbruck

T +43-512-9003-70725

F +43-512-9003-73700

[email protected]

Walter Buzina, MD

Institut für Hygiene

Medizinische Universität

Universitätsplatz 4

8010 Graz

T +43-316-380-7719

F +43-316-380-9648

walter.buzina@meduni-

graz.at

Ulrich Strasser. MD

Institut für Pathologie

Medizinische Universität

Innsbruck

Müllerstr. 44

A-6020 Innsbruck

T +43-512-9003-71304

F +43-512-582-088

[email protected]

Brazil

Marcio Nucci, MD

Hospital Universitário

Universidade Federal do Rio

de Janeiro

Av. Brigadeiro Trompovsky

21941-590 Rio de Janeiro

T +55-21-2562-2463

[email protected]

Czech Republic

Zdeněk Ráčil, MD

Dept. of Internal Medicine

Hemato-Oncology

University Hospital Brno

Jihlavska 20

62500 Brno

T +420-53223-2830/3642

F +420-53223-3603

[email protected]

Iva Kocmanova, MD

Dept. of Microbiology

University Hospital Brno,

Jihlavska 20

62500 Brno

T +420 53223 2974

[email protected]

Martina Lengerova, MD

Dept. of Internal Medicine

Hemato-Oncology

University Hospital Brno

Jihlavska 20

62500 Brno

T +420 53223 3642

[email protected]

Mojmir Moulis, MD

Dept. of Pathology

University Hospital Brno

Jihlavska 20

62500 Brno

T +420 53223 1111

[email protected]

Ludmila Malaskova, MD

Dept. of Biochemistery

University Hospital Brno

Jihlavska 20

62500 Brno

T. +420 53223 3073

[email protected]

Report December 2014 20

Clinical ID Microbiology Molecular Biology Pharmacology Pathology

Germany

Oliver A. Cornely, MD, FIDSA,

FACP

Klinikum der Universität

Klinik I für Innere Medizin

50924 Köln

T +49 221 478-6494

F +49 221 478-3611

[email protected]

Hilmar Wisplinghoff, MD

Klinikum der Universität

Institut f. Mikrobiologie,

Immunologie u. Hygiene

Goldenfelsstr. 19-2

50935 Köln

T +49 221 478 32023

hilmar.wisplinghoff@uk-

koeln.de

Ralf Bialek, MD

MVZ Labor Dr. Krause

Steenbeker Weg 25

24106 Kiel

T +49-431 388 252

[email protected]

Fedja Farowski, Biochemist

Klinikum der Universität

Institut für Pharmakologie

50924 Köln

T +49 221 478 87275

F +49 221 478 3611

[email protected]

Birgid Markiefka

Klinikum der Universität

Institut für Pathologie

50924 Köln

birgid.markiefka@uk-

koeln.de

Volker Rickerts, MD

Robert Koch Institute

Postbox: 650280

13302 Berlin

T +49 30 18754 2862

[email protected]

India

Anupma Jyoti Kindo, MD

Dept. of Microbiology

Sri Ramachandra Medical

College/Research Institute

No.1, Ramachandra Nagar

Porur, Chennai, 600 116

T +91 944 523-9196

[email protected]

Anuradha Chowdary

Department of Medical

Mycology

Vallabhbhai Patel Chest

Institute

University of Delhi

Delhi 110 007

T +91 11 2766 7560

[email protected]

Report December 2014 21

Clinical ID Microbiology Molecular Biology Pharmacology Pathology

Israel

Morad Wattad, MD

Rabin Medical Center

Infectious Diseases Unit

39 Jabotinski St.

49100 Petah Tikva

T +972-3-937-7377

F +972-3-937-6365

[email protected]

Italy

Livio Pagano, MD

Dipartimento di Ematologia

Universita Cattolica del Sacro

Cuore (Roma)

Largo Francesco Vito 1

00168 Roma

T +39-6-355-03953

F +39-630-51343 [email protected]

Maurizio Sanguinetti, MD

Istituto di Microbiologia

(Roma)

Università Cattolica del Sacro

Cuore

Largo Francesco Vito 1

00168 Roma

T +39-06-3015-4964

F +39-06-3051-152

[email protected]

Annamaria Tortorano, MD

Dip. Sanità Pubblica-

Microbiologia-Virologia Milano

Università di Milano

Via Pascal, 36/38

20133 Milano

T +39-2-503-15145

F +39-2-503-15146

[email protected]

t

Andrea Novelli, MD

Dipartimento di Farmacologia

Università degli Studi di

Firenze

Viale Pieraccini, 6

50139 Firenze

T +39-055-4271-286

F +39-055-4271-280

[email protected]

Gianluigi Vago, MD

Department of Clinical

Sciences

Luigi Sacco Hospital

University of Milan

Via Pascal, 36/38

20133 Milano

T +39 0285994869

F +39 0285994800

[email protected]

Turkey

Sevtap Arikan-Akdagli, MD

Mycology Laboratory

(Ankara)

Hacettepe University

06100 Ankara

F +90 (312) 3115250

[email protected]

Report December 2014 22

Active Partners

Australia

Melbourne

Royal Melbourne Hospital Infectious Diseases Nenad Macesic

Royal Melbourne Hospital Clinical Centre of Excellence in Infectious Diseases

Monica Slavin

Westmead

Westmead Hospital Molecular Mycology Research

Laboratory Sharon Chen

Austria

Graz

Medical University of Graz Department of Internal Medicine, Joint Facilities,

Division of Pulmonology

Martin Hoenigl

Innsbruck

Innsbruck Medical University Division of Hygiene und Medical Microbiology (HMM)

Cornelia Lass- Flörl

Wien

AKH Wien Klinisches Institut für Hygiene und Medizinische Mikrobiologie

Birgit Willinger

Belgium

Leuven

University Hospitals Leuven Department of Pharmaceutical and Pharmacological Science

Isabel Spriet

University Hospitals Leuven Laboratory of Clinical

Bacteriology and Mycology

Edith

Vermeulen

University Hospitals Leuven Department of Haematology Johan Maertens

Brazil

Curitiba

Hospital de Clinicas, Federal University of Paraná

Laboratory of Mycology Flavio de Queiroz Telles

Porto Alegre

Universidade Federal do Rio Grande do Sul (UFRGS)

Department of Paediatrics Denise Pereira

Universidade Federal do Rio

Grande do Sul (UFRGS)

Department Molecular

Diagnostic Laboratory

Alessandro

Pasqualotto

Canada

Montreal

Université de Montréal CHU Sainte-Justine, Pédiatres

infectiologues

Philipe

Ovetchkine

McGill University Department Microbiology and Immunology

Don Sheppard

China

Zhejiang

Zhejiang University Pulmonary Department Zhang Jin

Report December 2014 23

Cuba

Habana

Instituto de Hematologia e

Imunologia

Alberto Arencibia

Núñez

Czech Republic

Brno

University Hospital Brno Department of Internal

Medicine Hemato-Oncology Zdenek Racil

Denmark

Copenhagen

Copenhagen University

Hospital Rigshospitalet Department of Haematology

Emil

Hermansen

Finland

Turku

Turku University Hospital Department of Medical Microbiology and Immunology

Jarmo Oksi

France

Strasbourg

University Hospital of Strasbourg

Hôpital de Hautepierre, Department of Oncology and

Hematology

Raoul Herbrecht

Argenteuil

Centre Hospitalier

d’Argenteuil Réanimation Polyvalente

Gaëtan

Plantefève

Germany

Aachen

Uniklinik RWTH Aachen

Medizinische Klinik IV, Klinik

für Onkologie, Hämatologie und Stammzelltransplantation

Carolin Becker

Berlin

Robert Koch Institut Abteilung für

Infektionskrankheiten Volker Rickerts

Charité -

Universitätsmedizin Berlin

Universitätsklinik für Allgemein-, Viszeral-, Gefäß-

und Thoraxchirurgie

Sebastian

Friese

Charité -

Universitätsmedizin Berlin

Universitätsklinik für Allgemein-, Viszeral-, Gefäß-

und Thoraxchirurgie

Barbara

Korinth

Charité - Universitätsmedizin Berlin

Center for Cardiovascular Research (CCR)

Oskar Wischnewski

Dresden

University Hospital Dresden Medizinische Klinik und Poliklinik I

Nael Alakel

Dortmund

Klinikum Dortmund Nord Abteilung Pneumologie und

Infektiologie Stefanie Später

Report December 2014 24

Erlangen

Universitätsklinikum Erlangen

Medizinische Klinik 5 –

Hämatologie und Internistische Onkologie

Stefan Kallert

Universitätsklinikum Erlangen

Medizinische Klinik 5 –

Hämatologie und Internistische Onkologie

Lisa Meintker

Universitätsklinikum Erlangen

Medizinische Klinik 5 –

Hämatologie und Internistische Onkologie

Vanessa Hofmann

Essen

Universitätsklinikum Essen Institut für Medizinische Mikrobiologie

Jörg Steinmann

Frankfurt am Main

Universitätsklinikum

Frankfurt Abteilung Infektiologie Johanna Kessel

Frankfurt an der Oder

Klinikum Frankfurt Oder Abteilung Unfallchirurgie Dirk Kunzmann

Freiburg

Universitätsklinikum

Freiburg

Klinik für Innere Medizin I, Abteilung Hämatologie,

Onkologie und

Stammzelltransplantation

Hartmut Bertz

Göttingen

Georg-August-Universität Abteilung Hämatologie und Onkologie

Silke Neumann

Greifswald

Ernst-Moritz-Arndt-Universität Greifswald

Friedrich Loeffler Institut für Medizinische Mikrobiologie

Katrin Schulz

Halle-Wittenberg

Martin-Luther-Universität Halle-Wittenberg

Klinik für Innere Medizin IV, Onkologie und Hämatologie

Hans-Joachim

Schmoll, Maximillian

Christopeit

Heidelberg

Ruprecht-Karls-Universität

Heidelberg

Medizinische Klinik V, Abt.

Hämatologie, Onkologie und Rheumatologie

Martina

Gronkowski

Ruprecht-Karls-Universität

Heidelberg

Medizinische Klinik V, Abt.

Hämatologie, Onkologie und Rheumatologie

Gerlinde Egerer

Universitätsklinikum

Heidelberg ThoraxKlinik

Maren

Schuhmann

Homburg/Saar

Universitätsklinikum des

Saarlandes und Medizinische Fakultät der Universität des

Saarlandes

Klinik für Pädiatrische Onkologie und Hämatologie

Arne Simon

Jena

Universitätsklinikum Jena

Klinik für Kinder- und Jugendmedizin, Sektion

Hämatologie, Onkologie,

Stammzelltransplantation

Bernd Gruhn

Report December 2014 25

Universitätsklinikum Jena

Klinik, Zentrum für

Infektionsmedizin und Krankenhaushygiene

Stephanie

Beier

Universitätsklinikum Jena

Klinik, Zentrum für

Infektionsmedizin und Krankenhaushygiene

Mathias Pletz

Karlsruhe

Städtisches Klinikum

Karlsruhe Medizinische Klinik III

Jean-Charles

Moulin

Köln

Uniklinik Köln, Klinik I für

Innere Medizin Klinik I für Innere Medizin Oliver Cornely

Uniklinik Köln, Klinik I für Innere Medizin

Klinik I für Innere Medizin Fedja Farowski

Uniklinik Köln, Klinik I für

Innere Medizin Klinik I für Innere Medizin

Maria J.G.T.

Vehreschild

Uniklinik Köln, Klinik I für

Innere Medizin Klinik I für Innere Medizin

J. Janne

Vehreschild

Uniklinik Köln, Klinik I für Innere Medizin

Klinik I für Innere Medizin Kerstin Wahlers

Magdeburg

Städtisches Klinikum Magdeburg

Hämatologie/ Onkologie Kersten Borchert

München

Klinikum der Universität München (LMU)

Medizinische Klinik und

Poliklinik IV, Klinische

Infektiologie

Johannes Bogner

Klinikum München Krankenhaushygiene Elisabeth

Meyer

Münster

Universitätsklinikum

Münster

Klinik für Kinder- und

Jugendmedizin- Pädiatrische Hämatologie und Onkologie

Andreas Groll

Universitätsklinikum

Münster

Klinik für Kinder- und

Jugendmedizin- Pädiatrische Hämatologie und Onkologie

Gerda Silling

Postdam

Ernst von Bergmann Klinikum

Klinik für Hämatologie, Onkologie und Palliativmedizin

Georg Maschmeyer

Ulm

Uniklinik Ulm

Klinik III für Innere Medizin,

Sektion Infektiologie und Klinische Immunologie

Georg Härter

Würzburg

Universitätsklinikum Würzburg

Medizinische Klinik und Poliklinik II, Abtl. Leber- und

Infektionsambulanz

Werner Heinz

Universitätsklinikum Würzburg

Medizinische Klinik und Poliklinik II, Abtl. Leber- und

Infektionsambulanz

Andrew Ullmann

Universitätsklinikum Würzburg

Medizinische Klinik und Poliklinik II, Abtl. Leber- und

Infektionsambulanz

Anna Kuhn

Report December 2014 26

Universitätsklinikum

Würzburg

Medizinische Klinik und

Poliklinik II, Abtl. Leber- und Infektionsambulanz

Carolin

Spielau-Gleidies

Greece

Athens

Attikon University Hospital Department of Emergency and Critical Care

Elisabeth Paramythiotou

Attikon University Hospital Laboratory for Clinical

Microbiology

Joseph

Meletiadis

Hungary

Budapest

Semmelweis University First Department of Medicine Judit Demeter

Szeged

University of Szeged Faculty of Science, Department of Microbiology

Lorant Hatvani

University of Szeged

Albert Szent-Györgyi Clinical

Centre, Department of Clinical Microbiology

László Bereczki

University of Szeged Department Of Microbiology Laszlo Kredics

India

Ahmedabad

Infectious Diseases Clinic "VEDANTA" Institute of Medical

Sciences Navarangpura Atul Patel

Chandigarh

Government Medical College

Hospital (GMCH) Department of Microbiology

Jagdish

Chander

Mumbai

Hinduja Hospital Sangmesh Chavanda

Porur

Sri Ramachandra University Medical College

Department of Microbiology Anupma Jyoti Kindo

Israel

Holon

Edith Wolfson Medical Center

Department of Otolaryngology – Head & Neck Surgery

Yehudah Roth

Jerusalem

Hadassah University Medical Center

Department of Internal Medicine, Infectious Diseases

Maya Korem

Shaare Zedek Medical

Center Infectious Disease Unit Eli Ben-Chetrit

Petah Tikva

Rabin Medical Center Infectious Diseases Unit Morad Wattad

Italy

Bari

University of Bari Aldo Modo Department of Biomedical Science and Human Oncology

Maria Teresa Montagna

Report December 2014 27

Brescia

Spedali Civili Department of Hematology Chiara

Cattaneo

Padova

Policlinico G.B. Rossi Oncoematologia Pediatrica Simone Cesaro

Palermo

University of Palermo Department of Internal Medicine

Pasquale Mansueto

Rome

Universita Cattolica del Sacro Cuore

Istituto di Microbiologia Maurizio Sanguinetti

Netherlands

Nijmegen

Canisius-Wilhelmina Ziekenhuis Hospital

Department of Medical Microbiology

Jacques Meis

Romania

Iași

Universitatea Petre Andrei Department of Mycology-Mycotoxicology

Mihai Mares

Russia

Moscow

Federal research center of pediatric hematology,

oncology and immunology

named after Dmitry Rogachev

Infection Control Department Galina Solopova

St. Petersburg

St. Petersburg Medical

Academy of Postgraduate Education

Department of Clinical

mycology allergology and immunology

Nikolay Klimko

St. Petersburg Medical

Academy of Postgraduate Education

Department of Clinical

mycology allergology and immunology

Sofya Khostelidi

Serbia

Belgrade

University of Belgrade Institute for Microbiology and

Immunology

Valentina Arsic

Arsenijevic

Slovakia

Bratislava

National Cancer Institute Lubos Drgona

Thailand

Khon Kaen

Khon Kaen University Division of Infectious Diseases

and Tropical Medicine

Ploenchan

Chetchotisakd

Bangkok

Chulalongkorn University Department of Medicine, Division of Infectious Diseases

Chusana Suankratay

Report December 2014 28

Tunisia

Sousse

CHU Farhat Hached of Sousse and the Faculty of

Medicine of Sousse

Akila Fathallah

Turkey

Ankara

Hacettepe University Medical School

Department of Medicine,

Section of Infectious Diseases and Clinical Microbiology

Sevtap Arikan

Antalya

Akdeniz University Medical Faculty

Department of Clinical Microbiology

Dilara Ogunc

United Kingdom

London

Imperial College London,

Faculty of Medicine Department of Medicine

Darius Armstrong-

James

USA

Cleveland

Cleveland Clinic Lerner College of Medicine of Case

Western University

Department of Infectious

Diseases, Section of Transplant

Infectious Diseases, Medicine Institute and

Sherif Beniameen

Mossad

Report December 2014 29

Partners

Angola

Luanda

University of Luanda Department of Microbiology Moises Francisco

Argentina

Buenos Aires

El Centro de Internacion de FUNDALEU

Departamento Medico, REMIIN (Registro de Micosis Invasoras)

Maria Cecilia Dignani

Instituto Nacional de

Enfermedades Infecciosas „Dr. C.G. Malbran”

Susana Cordoba

Rosario

Universidad Nacional de Rosario

Centro de Referencia de Micologia Facultad de Ciencias

Bioquimicas

Maria Biasoli

University Hospital Rosario Centro de Transplante de Medula Osea de Rosario

(CETRAMOR)

Jose Anibal Cozzi

Australia

Perth

Royal Perth Hospital Department of Microbiology

and Infectious Diseases

Christopher

Heath

Austria

Baden

Landesklinikum Baden-

Mödling

Anästhesiologie und

Intensivmedizin

Franz

Schwameis

Feldbach

LKH Feldbach Abteilung für Innere Medizin -

Fürstenfeld, Hämato-Onkologie

Christina

Leitner

Feldkirch

Landeskrankenhaus Feldkirch

Abteilung für Innere Medizin Bernd-Lorenz Hartmann

Graz

Medizinische Universität Graz

Institut für Hygiene, Mikrobiologie und

Umweltmedizin

Walter Buzina

Innsbruck

Medizinische Universität

Innsbruck

Institut für Hygiene,

Mikrobiologie und Sozialmedizin

Anna Huppert,

Medizinische Universität

Innsbruck

Institut für Hygiene,

Mikrobiologie und Sozialmedizin

Isabella Schalk

Medizinische Universität

Innsbruck Institut für Pathologie Ulrich Strasser

Klagenfurt

Landeskrankenhaus Klagenfurt

Krankenhaushygiene Ulrich Zerlauth

Report December 2014 30

Linz

Allgemeines Krankenhaus

Linz Kinder- Herzzentrum Linz

Werner

Moosbauer

Wagner-Jauregg

Nervenklinik Klinik für Anästhesiologie Udo Illievich

Salzburg

Salzburger

Universitätsklinikum

Zentrum für

Krankenhaushygiene und Infektionskontrolle

Markus Hell

St. Pölten

Landesklinikum St. Pölten 1. Medizinische Abteilung Petra Pichler

Steyr

Landeskrankenhaus Steyr Institut für Anästhesie und

Intensivmedizin

Achim von

Goedecke

Wien

Hanusch-Krankenhaus der

Wiener Gebietskrankenkasse

Institut für Pathologie und

Mikrobiologie Uwe König

Hanusch-Krankenhaus der Wiener Gebietskrankenkasse

3. Medizinische Abteilung,

Hämatologisch-Onkologisches

Zentrum

Michael Pfeilstöcker

Medizinische Universität Wien

Universitätsklinik I für Innere

Medizin, Infektionen und

Tropenmedizin

Christina

Forstner (nee

Kratzer)

Medizinische Universität Wien

Universitätsklinik I für Innere

Medizin, Infektionen und

Tropenmedizin

Wolfgang Pöppl

Medizinische Universität Wien

Universitätsklinik I für Innere

Medizin, Infektionen und

Tropenmedizin

Peter Starzengruber

Medizinische Universität Wien

Universitätsklinik I für Innere

Medizin, Infektionen und

Tropenmedizin

Christoph Steininger

Medizinische Universität

Wien

Klinik für Dermatologie,

Abteilung für

Immundermatologie und Infektiöse Hauterkrankungen

Katharina Grabmeier-

Pfistershammer

Wilhelminenspital Wien Abteilung für Anästhesie,

Intensiv- und Schmerzmedizin Peter Wimmer

Universitätsklinik für

Krankenhaushygiene und

Infektionskontrolle

Elisabeth Presterl

Belarus (Republic of)

Minsk

Republic Research Center

for Pediatric Oncology Hematology and Immunolog

Sviatlana

Kandaurava

Belgium

Leuven

KU Leuven

Faculty of Medicine,

Department of Microbiology and Immunology, Laboratory

of Clinical Bacteriology and Mycology

Katrien Lagrou

Report December 2014 31

Mons

CHU Ambroise Paré Unité d’hémato-oncologie Marc Antoine

Brazil

Salvador da Bahia

Hospital Universitario

Professor Edgard Santos – UFBA

Serviço de Oncohematologia / TMO

Marco Aurélio Salvino

Hospital Universitario

Professor Edgard Santos – UFBA

Serviço de Oncohematologia / TMO

Monica Botura

Rio de Janeiro

Hospital Universitário Clementino Fraga (UFRJ)

Hematology and Mycology Laboratory

Marcio Nucci

Canada

Calgary

Peter Lougheed Center Department of Medicine, Section of Infectiuos Diseases

Andrew Johnson

Montreal

Jewish General Hospital Department of Microbiology and Infectious Diseases

Mark Miller

Quebec

Laboratoire de santé

publique du Quebec Secteur Mycologie

Philippe

Dufresne

Hamilton/Ontario

McMaster University Department of Medicine,

Division of Infectious Diseases Shariq Haider

McMaster University Department of Medicine, Division of Infectious Diseases

Tracy Reed

Hamilton General Hospital

Department of Medicine,

Division of Medical Microbiology

Debbie

Yamamura

Vancouver

Vancouver General Hospital Microbiology Laboratory Diane Roscoe

Chile

Santiago de Chile

Clínica Alemana Unidad de Infectología Luis Thompson

Moya

Valparaíso

Universidad de Valparaíso Facultad de Medicina Thomas Weitzel

China

Beijing

Peking University People's

Hospital Institute of Hematology

Feng-Rong

Wang

Guangdong

Guangdong General Hospital Department of Hematology Xin Du

Guangzhou

GuangZhou NanFang hospital

Respiratory and critical care medicine Department

Su Jin

Report December 2014 32

Hangzhou

Zhejiang University School of Medicine

The First Affiliated Hospital,

Bone Marrow Transplant Center

He Huang

Shanghai

Changhai Hospital Department of Hematology Jian-Min Yang

Columbia

Medellin

Conjunto Residencial Montevideo

Angela Restrepo

Conjunto Residencial

Montevideo Angela Tobón

Croatia

Zagreb

Zagreb University Hospital

Centre Division of Internal Medicine Nemet Damir

Zagreb University Hospital Centre

Division of Internal Medicine Radovan Vrohvac

Czech Republic

Olomouc

Palacky University Faculty of Medicine, Department of Microbiology

Petr Hamal

Denmark

Copenhagen

Copenhagen University Hospital

Deptartment of Hematology Jannik Helweg-Larsen

Rigshospitalet Department of Hematology-Granulocyte Research Lab.

Andreas

Birkedal Glenthøj

France

Montpellier

Service de soins intensifs en

hématologie Patrice Ceballos

Nantes

CHU Hematology Pierre Peterlin

Paris

Hospital Saint-Louis Département d'Hématologie Emmanuel

Raffoux

Hospital Saint-Louis Département d'Hématologie Patricia Ribaud

Germany

Aachen

Medizinisches Zentrum Städteregion Aachen

Klinik für Orthopädie Rolf Sobottke

Augsburg

Klinikum Augsburg II. Medizinische Klinik, Einheit für Stammzelltransplantation

Christoph Schmid

Bad Kreuznach

Sana Rheumazentrum

Rheinland-Pfalz AG Rheumatologische Ambulanz Eckhard Weber

Report December 2014 33

Berlin

Vivantes Krankenhaus Klinik für Hämatologie und

Onkologie Jörg Beyer

Vivantes Krankenhaus Klinik für Hämatologie und Onkologie

Markus Müller

DRK Kliniken Berlin Olaf Süss

Charité-Universitätsmedizin Berlin

Medizinische Klinik und Poliklinik II

Markus Ruhnke

Charité-Universitätsmedizin

Berlin

Center für Muskuloskeletale

Chirurgie Andrej Trampuz

Robert Koch Institut Abteilung für

Infektionskrankheiten Michael Seibold

Helios-Klinikum Berlin-Buch Klinik für Neurologie Franz- Josef Dieste

Bielefeld

Städtische Kliniken Bielefeld gem.GmbH

Klinik für Hämatologie, Onkologie & Palliativmedizin

Martin Görner

Bochum

Klinikum der Ruhr-Universität Bochum

St. Josef Hospital,

Gastroenterologie und

Infektiologie

Renate Schlottmann

Bonn

Universitätsklinikum zu Bonn

Klinik für Neonatologie Cornelia Graef

Universitätsklinikum zu

Bonn

Medizinische Klinik und

Poliklinik III Axel Kaeferstein

Universitätsklinikum zu Bonn

Medizinische Klinik und Poliklinik III

Dominik Wolf

Borstel

Medical Clinic

Research Center Borstel,

Division of Clinical Infectious

Diseases

Christoph Lange

Bremen

Klinikum Bremen-Mitte Medizinische Klinik I Henrike Thomssen

Dortmund

Klinikum Dortmund Nord Abteilung Pneumologie/Infektiologie

Bernhard Schaaf

Klinikum Dortmund Nord Abteilung

Pneumologie/Infektiologie Greta Ullrich

Dresden

University Hospital Dresden Medizinische Klinik und Poliklinik I

Ulrich Schuler

Krankenhaus Dresden-

Friedrichstadt Dermatologie Gesina Hansel

Krankenhaus Dresden-Friedrichstadt

Mykologisches Labor Irina Vennewald

Düsseldorf

Universitätsklinikum

Düsseldorf HNO-Klinik Katrin Gollner

Universitätsklinikum Düsseldorf

HNO-Klinik Kathrin Scheckenbach

Report December 2014 34

Universitätsklinikum

Düsseldorf

Klinik für Hämatologie,

Onkologie und klinische Immunologie

Thomas

Schröder

Erlangen

Uniklinik Erlangen

Medizinische Klinik 5 –

Hämatologie und Internistische Onkologie

Stefan Krause

Uniklinik Erlangen

Medizinische Klinik 5 –

Hämatologie und Internistische Onkologie

Wolf Rösler

Essen

Universitätsklinikum Essen Klinik für Knochenmarktransplantation

Rudolf Trenschel

Universitätsklinikum Essen Klinik für Nephrologie Oliver Witzke

Kliniken Essen Süd

Klinik für Hämatologie/

Internistische Onkologie und

Stammzelltransplantation

Mohammed Wattad

Frankfurt am Main

Infektiologikum Frankfurt Gaby Knecht

Onkologikum Frankfurt Angelika Böhme

Klinikum der Johann

Wolfgang Goethe-Universität

Zentrum für Kinder- und

Jugendmedizin, Klinik III

Thomas

Lehrnbecher

Klinikum der Johann

Wolfgang Goethe-Universität

Zentrum für Innere Medizin, Medizinische Klinik II –

Hämatologie, Onkologie,

Rheumatologie, Infektiologie

Anjali Dubey

AGAPLESION Markus-

Krankenhaus Klinik für

Palliativmedizin

Sabine Mousset

Frankfurt an der Oder

Klinikum Frankfurt Oder Abteilung für Innere Medizin, Hämatologie und Onkologie

Michael Kiehl

Freiburg

Universitätsklinikum Freiburg

Hämatologie und Onkologie Werner Neubauer

Universitätsklinikum

Freiburg Helmut Lang

Universitätsklinikum

Freiburg

Zentrum für Infektiologie und

Reisemedizin Dirk Wagner

Geesthacht

Medizinischen

Versorgungszentrum Dr. Kramer und Kollegen

LADR GmbH Ralf Bialek

Göttingen

Universitätskliniken Göttingen

Institut für Medizinische Mikrobiologie

Uwe Groß

Greifswald

Universitätsklinikum der Ernst-Moritz-Arndt-

Universität Greifswald

Klinik und Poliklinik für Innere

Medizin C, Hämatologie und Onkologie-

Transplantationszentrum

William Krüger

Halle (Saale)

Report December 2014 35

Universitätsklinikum Halle

(Saale)

Claudia

Wickenhauser

Halle-Wittenberg

Martin-Luther-Universität Halle-Wittenberg

Klinik für Innere Medizin IV, Onkologie und Hämatologie

Hans- Heinrich Wolf

Hamburg

Asklepios Klinik St. Georg Institut für Infektiologie M. Sabranski

Heidelberg

Universitätsklinikum

Heidelberg

Medizinische Klinik V, Abt.

Hämatologie, Onkologie und Rheumatologie

Johann-Wilhelm

Schmier

Universitätsklinikum

Heidelberg

Medizinische Klinik V, Abt.

Hämatologie, Onkologie und Rheumatologie

Gerlinde Egerer

Universitätsklinikum

Heidelberg

Medizinische Klinik V, Abt.

Hämatologie, Onkologie und Rheumatologie

Nicola Lehners

Universität Heidelberg Abteilung für Infektiologie,

Sektion Krankenhaushygiene

Alexandra

Heininger

Zelluläre Immuntherapie Medizinische Universitätsklinik V

Michal Schmitt

Homburg/Saar

Universitätskliniken des

Saarlandes Innere Medizin I Jörg Bittenbring

Karlsruhe

Städtisches Klinikum

Karlsruhe Medizinische Klinik III

Jean-Charles

Moulin

Kiel

Universitätsklinikum

Schleswig-Holstein

Medizinische Klinik und

Poliklinik II Heinz-A. Horst

Köln

Kliniken der Stadt Köln Krankenhaus Merheim, Institut für Hygiene

Frauke Mattner

Konstanz

Klinikum Konstanz Klinik für Anästhesiologie und Operative Intensivmedizin

Wolfgang Krüger

Leverkusen

Klinikum Leverkusen

Medizinische Klinik IV –

Allgemeine Innere Medizin, Infektiologie, Pneumologie,

Osteologie

Stefan Reuter

Lübeck

Universität Lübeck Institut für Medizinische

Mikrobiologie und Hygiene Jan Rupp

Mainz

Johannes-Gutenberg-Universität

III. Medizinische Klinik und

Poliklinik, Hämatologie, internistische Onkologie,

Pneumologie

Ralf Georg Meyer

Universitätsmedizin Mainz I. Medizinische Klinik und Poliklinik, Innere Medizin

Martin Sprinzl

Report December 2014 36

Mannheim

Universitätsklinikum

Mannheim III. Medizinische Klinik Anne Dietz

Mönchengladbach

MVZ Stein und Kollegen

Laboratoriumsmedizin,

Mikrobiologie, Infektionsepidemiologie

Roman Schwarz

München

Ludwig- Maximilians-Universität München

Medizinische Klinik und

Poliklinik IV, Abteilung für

Infektions- und Tropenmedizin

Thomas Löscher

Klinikum Harlaching

Städtisches Klinikum München

GmbH, Klinik für Hämato-

Onkologie

Meinolf Karthaus

Klinikum Harlaching

Städtisches Klinikum München

GmbH, Klinik für Hämato-

Onkologie

Xaver Schiel

Klinikum der Universität

München-Großhadern

Kinderkardiologie und

Pädiatrische Intensivmedizin Markus Loeff

Klinikum der Universität München-Großhadern

Klinik für Hals-, Nasen- und Ohrenheilkunde

Robert Guerkov

Klinikum der Universität

München-Großhadern Medizinische Klinik III

Helmut

Ostermann

Klinikum der Universität München-Großhadern

Medizinische Klinik III Lisa Peterson

Münster

Uniklinik Münster Medizinische Klinik A Felix Rosenow

Mutlangen

Klinikum Schwäbisch Gmünd

Stauferklinik,

Hämatologie/Onkologie/Immunologie/Rheumatologie

Holger Hebart

Rostock

Universitätsklinikum Rostock

Klinik und Poliklinik für Innere Medizin, Abteilung für

Hämatologie, Onkologie, Palliativmedizin

Brigitte Kragl

Sindelfingen

Kliniken Sindelfingen Medizinische Klinik I,

Hämatologie und Onkologie,

Stefan

Neuburger

Tübingen

Universität Tübingen Klinik für Dermatologie Sybille Schmidt

Universität Tübingen Institut für Medizinische Mikrobiologie und Hygiene

Matthias Willmann

Witten

Marienhospital Witten Abteilung für Kinder- und

Jugendmedizin

Bahman

Gharavi

Universität Witten/Herdecke Medizinische Klinik 5- Hämatologie und Internistische

Onkologie

Stefan

Sauerland

Würzburg

Universität Würzburg Medizinische Klinik und

Poliklinik für Innere Medizin II Jürgen Löffler

Report December 2014 37

Universität Würzburg Medizinische Klinik und

Poliklinik für Innere Medizin II Hartwig Klinker

Universität Würzburg Institut für Hygiene und

Mikrobiologie Bhanu Sinha

Greece

Athens

Athens University 1st Department of Propaedeutic Medicine

Anna Skiada

Aghia Sophia Children´s

Hospital Cystic Fibrosis Department

Stavros

Doudounakis

Athens University

Infectious Diseases and

Antimicrobial Chemotherapy

Research Laboratory

George L. Petrikkos

General University Hospital

ATTIKON Maria Stamouli

Hungary

Budapest

Military Hospital Laszlo Rokusz

India

Bangalore

Narayana Health Bangalor Anil Kumar

Apollo Hospitals Ramaiah Curie Centre of Oncology

Purnima Parthasarathy

Mazumdar Shaw Hospital

Center Narayana Health Sunil Bhat

Chandigarh

Postgraduate Institute of

Medical Education & Research

Department of Medical

Microbiology

Arunaloke

Chakrabarti

Postgraduate Institute of

Medical Education & Research

Department of Pulmonary

Medicine Ritesh Agarwal

Chennai

Global Hospital and Health

City

Department of Infectious

Diseases

Subramanian

Swaminathan

Kolkata

Tata Medical Center Mammen

Chandy

Manipal

Manipal University Kasturba Medical College,

Department of Microbiology

Prakash

Yegneswaran

Mumbai

Grant Medical College and Sir J.J. Group of Hospitals

Department of Microbiology Sarala Menon

Jaslok Hospital Department of Infectious

Diseases Om Shrivastav

Global Hospitals Dhanashree Kelkar-

Galwankar

Report December 2014 38

New Delhi

Institute Rotary Cancer

Hospital Sameer Bakhshi

Institute Rotary Cancer Hospital

Lalit Kumar

Deen Dayal Upadhyayaa

Hospital Neelam Sood

University of Delhi Department of Medical Mycology Vallabhbhai Patel

Chest Institute

Anuradha Chowdhary

Pune

Jehangir Hospital Incharge Carciac Recovery Unit C.S. Sharma

Tiruchirapalli

Institute of Ophthalmology Philip A. Thomas

Indonesia

Jakarta

Mangunkusumo Hospital University of Indonesia, Department of Internal

Medicine

Erni Juwita

Nelwan

Ireland

Dublin

Dublin Saint James Hospital Trinity College, Department of

Microbiology Thomas Rogers

Israel

Haifa

Rambam Medical Center Infection Disease Unit Anat Shteren

Petah Tikva

Rabin Medical Center Department of Infectious

Disease Jihad Bishara

Tel Aviv

Sheba Medical Center Israel Department of Clinical

Microbiology Nathan Keller

Tel Aviv Sourasky Medical

Center Infectious Diseases Unit Ronen Ben-Ami

Tel Aviv Sourasky Medical Center

Infectious Diseases Unit Michal Dekel

Tel Aviv Sourasky Medical Center

Department of Otolaryngology,

Head and Neck Surgery and Maxillofacial Surgery

Dan M. Fliss

Italy

Bologna

Alma Mater Studiorum

Università di Bologna

Dipartimento di Scienze

Mediche e Chirurgiche

Russell Edward

Lewis

Firenze

Università degli Studi di Firenze

Dipartimento di Farmacologia Andrea Novelli

Genova

Ospedale San Martino Divisione di Ematologia e Trapianto di Midollo Osseo

Andrea Bacigalupo

Report December 2014 39

Milan

University of Milan

Laboratorio di Micologia

Medica, Sezione Sanità Pubblica

Anna Maria Tortorano

University of Milan Luigi Sacco Hospital, Pathology

Unit Gianluigi Vago

Humanitas Clinical Institute Concetta De Luca

Rome

Universita Cattolica del Sacro Cuore

Dipartimento di Ematologia Livio Pagano

San Camillo-Forlanini

Hospital Hematology Unit

Mariagrazia

Garzia

Palermo

Policlinico Gemelli Department of Infectious Diseases

Enrico Maria Trecarichi

Japan

Chiba

Chiba University Hospital Medical Mycology Research Center (MMRC), Division of

Clinical Research

Katsuhiko

Kamei,

Chiba University Hospital Medical Mycology Research Center (MMRC), Division of

Clinical Research

Akira Watanabe

Nagasaki

Nagasaki University Hospital Department of Molecular

Microbiology and Immunology Shigeru Kohno

Shizuoka

Shizuoka Cancer Center Division of Infectious Diseases Shinichiro

Morioka

Korea

Seoul

Center for Specific Organs Cancer

Research Institute and

Hospital, National Cancer Center, Hematology-Oncology

Clinic, Hematopoietic Stem Cell Transplantation Center

Hyeon Seok Eom

The Catholic University of

Korea

Department of Internal

Medicine, Division of Infectious Diseases

Dong-Gun Lee

Suwon

Ajou University School of Medicine

Department of Hematology-Oncology

Joon Seong Park

Kuwait

Kuwait City

Kuweit University Faculty of Medicine, Department of Microbiology

Eiman Mokaddas

Lebanon

Beirut

American University of Beirut Medical Center

Department of Medicine, Division of Infectious Disease

Souha Kanj-Sharara

Report December 2014 40

Lithuania

Vilnius

Vilnius University Hospital

Santariskiu Klinikos, Nephrology Centre,

Department of Nephrology, Kidney Transplantation and

Dialysis

Marius Miglinas

Vilnius University Hospital Santariskiu Klinikos, Department of Hematology

Indre Klimiene

Macedonia

Skopje

University Sts Cyril and Methodius

Medical Faculty, Institute for Microbiology and Parasitology

Gordana Mirchevska

Mexico

Guadalajara

Hospital Civil de Guadalajara

Fray Antonio Alcalde, Instituto

de Patología Infecciosa y Experimental

Eduardo

Rodriguez-Noriega

Mexico City

Ixtlamatia Clinical Research

S.A. de C.V

Miguel Ángel

Reséndiz

Sinaloa

Hospital General de Culiacán Ramón Rivas

Llamas

Netherlands

Groningen

University Medical Center

Groningen Jan P. Arends

Utrecht

New Zealand

Wellington

Aotea Pathology Microbiology Department Hongtao Liu

Nigeria

Lagos

University of Lagos College of Medicine Rita Oladele

North Ireland

Belfast

Belfast City Hospital Department of Bacteriology John E. Moore

Norway

Trondheim

Medisinsk Klinikk - St. Olav Hospital HF

Department of Infection Raisa Hannula

Peru

Lima

Hospital Nacional Edgardo

Rebagliati Martins Hematology/ BMT Department

Eduardo Fernandez-

Vertiz

Report December 2014 41

Poland

Gdansk

Medical University Gdánsk Agata Szymańska

Lodz

Medical University of Lodz

Department of Pediatrics,

Oncology, Hematology and

Diabetics

Filip Pierlejewski

Warsaw

Klinika Pediatrii Hematologii i Onkologii Dziecięcej

Magdalena Bartnik

Wroclaw

Wroclaw Medical University Oncology, Hematology and Diabetics

Jaroslaw Dybko

Portugal

Coimbra

Coimbra University Hospital Rui Tome

Porto

University of Porto Institute of Molecular

Pathology and Immunology Rita Caramalho

Hospital São João Ana Carneiro

Hospital São João Laboratorio de Microbiologia Maria Dolores

Pinheiro

Russia

Krasnodar City

Regional Children Hospital Tatiana

Askretova

Moscow

Russian Cancer Research

Centre Anton Ivanov

Vishnevsky Institute of

Surgery Andrey Chizhov

Federal research center of pediatric hematology,

oncology and immunology

named after Dmitry Rogachev

Infection Control Department Galina Solopova

St. Petersburg

I Pavlov State Medical

University Vladimir Vavilov

Saudi Arabia

Riyadh

King Fahad Medical City Department of Medicine Musa Garbati

King Faisal Specialist Hospital and Research

Center

Section of Infectious Diseases Hail Mater Al-

Abdely

Serbia

Belgrade

Clinic of hematology Clinical Centre of Serbia Ava Vidovic

Report December 2014 42

Novi Sad

Clinical center of Vojvodina Ivanka Savic-

Tatic

Singapore

Mount Elizabeth Medical

Centre Infectious Diseases Care Asok Kurup

University Medicine Center National University Health System (NUHS), Division of

Infectious Diseases

Chai Louis Yi Ann

National University Hospital Department of Pediatrics Infectious Diseases

Si Min Chan

South Africa

Cape Town

Groote Schuur Hospital University of Cape Town, Department of Orthopaedic

Surgery

Robert Dunn

Durban

University of KwaZulu-Natal

Nelson R. Mandela School of

Medicine, Department of Infection Prevention and

Control

Teke Apalata

Johannesburg

Hospital and University of Witwatersrand

Department of Medicine Mervyn Mer

Spain

Cadiz

Puerta del Mar University

Hospital

Clinical Microbiology

Laboratory

Manuel

Rodriguez-Iglesias

Huelva

Hospital Juan Ramon

Jimenez-Huelva

Grupo Andaluz de Leucemias

Agudas GALA

Eusebio Martín

Chacón

Madrid

Hospital de la Princesa

Servicio de Hematología de la

Unidad de Consejo y Cuidado Oncológico de Sanitas

Rafael de la

Cámara

Hospital la Paz Department of Hematology Pilar Gomez

Pietro

Murcia

Hospital Morales Meseguer Hematology and Medical Oncology Service

Pastora Iniesta Lopez-Matencio

Palma de Mallorca

University Hospital Son Espases

Antonia Sampol

Santander

Hospital Universitario

Marqués De Valdecilla Department of Hematology

Lucrecia Yanez

San Segundo

Sevilla

University Hospital Virgen

des Rocio/CSIC/University of Seville

Clinical Unit of Infectious

Disease, Microbiology and Preventative Medicine

Martin-Pena

Almudena

Report December 2014 43

Valencia

Hospital Universitario La Fe Servicio de Microbiología, Javier Peman

University Hospital La Fe Department of Hematology Rebeca Rodriguez-

Veiga

Schweden

Luleå

Sunderby Hospital Clinical Microbiological

Laboratory Peter Cettner

Lund

Skane University Hospital Department of Infectious

Diseases Gisela Otto

Spain

Oviedo

Asturias Central University

Hospital

María del Pilar

Palmo

Switzerland

Basel

Universitätsspital Basel Abteilung für Infektiologie und

Spitalhygiene

Andreas

Widmer

Universitätsspital Basel Abteilung für Infektiologie und Spitalhygiene

Ursula Flueckiger

Universitätsspital Basel Medizin I Abteilung für

Hämatologie Alois Gratwohl

Bern

Inselspital Universitätsklinik für

Infektiologie Stefan Zimmerli

Inselspital Klinik für Pneumologie Sebastian Ott

Taiwan, Province of China

Taipei

Far Eastern Memorial Hospital

Department of Internal

Medicine, Division of Infectious

Diseases

Chia- Ying Liu

National Taiwan University

Hospital

Tai-Chen Stem Cell Therapy

Center Jih-Luh Tang

National Taiwan University

Hospital

Department of Internal Medicine, Division of Infectious

Diseases

Yee-Chun Chen

Turkey

Ankara

Hacettepe University Medical School

Department of Medicine, Section of Infectious Diseases

Murat Akova

Hacettepe University Medical

School

Department of Medicine,

Section of Infectious Diseases Ömrün Uzun

Baskent University

Faculty of Medicine,

Department of Internal

Medicine, Division of Hematology

Can Boga

Gazi University Pediatric Hematology and

Oncology Ertan Sal

Report December 2014 44

Gazi University Pediatric Hematology and

Oncology Funda Tekkesīn

Istanbul

Beyoglu Eye Training and Research Hospital

Serhat Imamoglu

Capa University Zeynep Memis

Izmir

Dokuz Eylül University Faculty of Medicine, Division of Hematology

Fatih Demirkan,

Dokuz Eylül University Faculty of Medicine, Division of

Hematology

Ömür Gökmen

Sevindik

Kayseri

Erciyes University

Faculty of Medicine,

Department of Pediatrics Division of Pediatric

Hematology and Oncology

Ekrem Unal

Ukraine

Kiev

National Cancer Institute Kateryna

Filonenko

Ukranian National Children Hospital

Centre of pediatric hematology and BMT

Iulia Bazaluk

United Kingdom

Glasgow

Southern General Hospital Department of Microbiology Nitish Khanna

Kilmarnock

University Hospital Crosshouse

Department of Microbiology Abhijit Bal

Kingsgate

ID Consultancy Peter F. Troke

London

St Guys and St. Thomas

NHS Trust Jon Lambourne

Orpington

South London Healthcare NHS Trust

Princess Royal University Hospital

M. Mansour Ceesay

Swansea

Singleton Hospital Department of Microbiology Nidhika Berry

USA

Ann Arbor

Taubman Center Department of Internal Medicine, Division of Infectious

Diseases

Marisa Miceli

Baltimore

Johns Hopkins University School of Medicine

Department of Pathology, Division of Microbiology

Sean Zhang

Detroit

Henry Ford Medical Center Transplantation Infectious Diseases

Mayur Ramesh

Report December 2014 45

Denver

University of Colorado Department of Pathology Diane

Hutchinson

Duarte

City of Hope National

Medical Center Division of Infectious Diseases

Sanjeet Singh

Dadwal

Indianapolis

MiraVista Diagnostics and MiraBella Technologies

Patricia Connolly

Iowa City

University of Iowa College of Medicine, Department of Pathology,

Medical Microbiology Division,

Linda Boyken

Memphis

St. Jude Children's Research

Hospital Department of Surgery

John A.

Sandoval

Park Ridge

St. James School of Medicine

Harish Gugnani

Washington

University of Washington Division of Infectious Diseases Philip Coffin

Report December 2014 46