© 2014 Medidata Solutions, Inc.

Can Big Data/Real World Data Cure Life Science’s R&D Malaise?

Glen de VriesFounder and President

Development Commercial

Regulators Payers

EfficacyData

EffectivenessData

© 2014 Medidata Solutions, Inc.

Development Commercial

Regulators Payers

The Same Data

© 2014 Medidata Solutions, Inc.

*omics

Clinical

mHealth

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•MEDIDATA, AN INTRODUCTION

6

ENGAGE, COLLABORATE, INNOVATE

The GADGET Method Development Effort

+

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© 2014 Medidata Solutions, Inc.

Genetic Biomarkers

PhenotypicBiomarkers

Digital Biomarkers

© 2014 Medidata Solutions, Inc.

12

13

The Medidata MOVE-2014 Study

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SafetyPrivacy Regulation

Objections

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© 2014 Medidata Solutions, Inc.

Approval Patent Expiration

Val

ue (

The

rape

utic

& E

cono

mic

)

Time

Baseline Value

Commercial Patient Engagement Strategy

Clinical Development Patient Engagement

Strategy

lost annually from patients not taking their medicines

£350 Billion

TherapeuticBenefits!

+

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There will be life sciences companies using objectively measured digital biomarker data

with both regulators and payers…

And there will still be life sciences companiesthat are not

2020 Predictions

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10 years from now life sciences companies that don’t use digital

biomarkers as part of their solutions will no longer exist

© 2014 Medidata Solutions, Inc.

© 2014 Medidata Solutions, Inc.

Thank you!