VITAEblasts.uco.edu/centralities/files/CMS - Chen CV.pdfWei R. Chen, Ph.D. Page 2 of 80 Central Oklahoma Alliance for Physics Teaching, 1992-1996 Vice Chair, 1992-1993; Chair, 1993-1994

VITAE NAME: Wei R. Chen POSITION TITLE:

Interim Dean College of Mathematics and Science University of Central Oklahoma Director Center for Interdisciplinary Biomedical Education and Research (CIBER) College of Mathematics and Science University of Central Oklahoma Professor Biomedical Engineering Program

Department of Engineering and Physics University of Central Oklahoma

URL: http://faculty.uco.edu/cms/wchen EDUCATION: Shandong University, Jinan, China B.S. Feb. 1982 Physics University of Oregon, Eugene, Oregon M.S. June 1984 Physics University of Oregon, Eugene, Oregon Ph.D. Aug. 1988 Physics University of Oregon, Eugene, Oregon Postdoc. 1989 Physics PROFESSIONAL SOCIETY: American Physical Society, 1984-1995 SPIE- The International Society for Optics and Photonics, 1992-present Member: Executive Organizing Committee, Biomedical Optics (BiOS) Symposium, 2006-

Present Fellow, SPIE 2007-Present

Wei R. Chen, Ph.D.

Page 2 of 80

Central Oklahoma Alliance for Physics Teaching, 1992-1996 Vice Chair, 1992-1993; Chair, 1993-1994

Sigma Xi, 1999-Present President-Elect, University of Central Oklahoma Chapter, 2004-2005; 2011-2012 President, University of Central Oklahoma Chapter, 2005-2006; 2012-2013 Past President, University of Central Oklahoma Chapter, 2006-2007; 2013-2014 Oklahoma Academic of Science, 1999-present

Vice Chair, Engineering Science Section, 2002-2003 Chair, Engineering Science Section, 2003-2004 Vice Chair, Engineering Science Section, 2004-2005 Member of Oklahoma Academic of Science Council, 2002-2005

Council of Chinese American Deans and Presidents (CCADP) Founder and Member, 2007-present

Secretary/Treasurer, 2008-2010 ACADEMIC APPOINTMENTS: 1983-1988 Research Assistant, Institute of Theoretical Science, University of Oregon 1987-1988 Teaching Assistant, Department of Physics, University of Oregon 1988-1989 Assistant Professor of Physics, Parks College of St. Louis University 1989 Research Associate, Institute of Theoretical Science, University of Oregon 1990 Visiting Research Associate, Dept. of Physics and Astronomy, University of Oklahoma 1990-1996 Adjunct Assistant Professor of Physics, Dept. of Physics, University of Oklahoma 1989-1999 Instructor of Physics, Oklahoma School of Science and Mathematics 1994-1999 Lecturer of Physics, Department of Physics, University of Central Oklahoma 1998, Summer Visiting Research Scientist, Department of Radiology, University of Virginia 1999-2001 Assistant Professor of Physics and Engineering, Department of Physics and

Engineering, University of Central Oklahoma 1999-2000, Summer Visiting Research Scientist, Department of Radiology and Biomedical

Engineering, The Johns Hopkins University 2001, Summer Senior Research Scientist, School of Electrical Engineering, University of

Oklahoma 2001- 2005 Associate Professor of Physics and Engineering, Department of Physics and

Engineering, University of Central Oklahoma 2001- 2006 Director of Biomedical Engineering Program, Department of Physics and Engineering,

University of Central Oklahoma 2004- 2007 Adjunct Associate Professor of Physics, Department of Physics, College of Arts and

Sciences, Oklahoma State University 2007-Present Adjunct Professor of Physics, Department of Physics, College of Arts and Sciences,

Oklahoma State University 1996-Present Adjunct Associate Professor of Physics, Department of Physics, University of

Oklahoma 2001- Present Adjunct Associate Professor, School of Aerospace and Mechanical Engineering,

University of Oklahoma 2004- Present Adjunct Associate Professor of Veterinary Clinical Sciences, Department of Veterinary

Clinical Sciences, College of Veterinary Medicine, Oklahoma State University 2005 - Present Professor of Engineering and Physics, Department of Engineering and Physics,

University of Central Oklahoma 2006 - 2015 Assistant Dean, College of Mathematics and Science, University of Central Oklahoma

Wei R. Chen, Ph.D.

Page 3 of 80

2006 - 2009 Campus and Program Coordinator, National Science Foundation (NSF) SURE-STEP Program (Supporting Undergraduate Research and Education for the Science, Technology, Engineering, and Mathematics Talent Expansion Program), University of Central Oklahoma

2009 - 2015 Principal Investigator/Project Director, Oklahoma National Science Foundation (NSF) STEP Program, Oklahoma

2010 - Present Founder and Director, Center for Interdisciplinary Biomedical Education and Research (CIBER), College of Mathematics and Science, University of Central Oklahoma

2010 - Present SPIE (The International Society for Optics and Photonics)’s Alternate Director on the ABET Board

2015 - Present Interim Dean, College of Mathematics and Science, University of Central Oklahoma PROFESSIONAL EXPERIENCE: Conference Organization: Member Program Committee of SPIE International Conference of Laser-Tissue Interaction IX;

and Chair, “Immunologic Mechanisms During PDT” session, Photonics West; January 1998, San Jose, CA

Member Program Committee of SPIE International Conference of Biomedical Optics and Lasers: Diagnostics and Treatment; and Chair, “Cancer Treatment” session, Photonics China ‘98, September 16-19, 1998, Beijing, China

Member Program Committee of SPIE International Conference of Laser-Tissue Interaction X; and Chair, “Immunologic Responses to Thermal and PDT Effects” session, Photonics West; January 1999, San Jose, CA

Member International Academic Committee and Organization Committee, International Conference on Biomedical Optics (BMO ’99), October 25-27, 1999, Wuhan, China

Member Program Committee of SPIE International Conference of Laser-Tissue Interaction XI; and Chair, “PDT and Immunotherapy” session, Photonics West; January 2000, San Jose, CA

Member Program Committee of the 13th IEEE Symposium on Computer-Based Medical Systems, June 23-24, 2000, Houston, TX

Member Program Committee of SPIE International Conference of Biomedical Photonics and Optoeletronic Imaging; and Chair, “Applications” session, November 8-10, 2000, Beijing, China

Member Program Committee of SPIE International Conference of Laser-Tissue Interaction XII; and Chair, “PDT and Immunotherapy” and “PDT” sessions, Photonics West; January 2001, San Jose, CA

Member Program Committee of Wuhan International Workshop on Photonics and Imaging in Biology and Medicine (PIBM’01); and Chair of two sessions, October 8-10, 2001, Wuhan, China

Member Program Committee of SPIE International Conference of Laser-Tissue Interaction XIII; and Chair, “Photochemical and thermal injury effects that induce immune responses to cancer” sessions, Photonics West; January 2002, San Jose, CA

Wei R. Chen, Ph.D.

Page 4 of 80

Chair Saratov International Workshop on Biophotonics – SIWB-02, June 19 - 21, 2002, Saratov, Russia

Member Program Committee of SPIE International Conference of Optics in Health Care and Biomedical Optics: Diagnostics and Treatment, Photonics Asia; October 14-18, 2002, Shanghai, China

Member Program Committee of SPIE International Conference of Laser-Tissue Interaction XIV; and Chair, “PDT and Photothermal Effects on Immunologic Responses” session, Photonics West; January 2003, San Jose, CA

Member International Advisory Committee and Program Committee of International Conference Photonics Pacific Rim - Photonics and Imaging in Biology and Medicine (PIBM2003), June 8-12, 2003, Wuhan, China

Member Program Committee of International Conference of Advanced Laser Technologies (ALT’03), September 19-23, 2003, Bedfordshire, United Kingdom

Member International Program Committee, Saratov Fall Meeting 2003: Optical Technologies in Biophysics and Medicine V, October 7-10, 2003, Saratov, Russia

Moderator Engineering Sciences Section, Oklahoma Academy of Science 92nd Technical Meeting, November 7, 2003, Chickasha, Oklahoma

Member Program Committee of SPIE International Conference of Laser Interaction with Tissue and Cells XV; and Chair, “Photodynamic Therapy I” and “Photodynamic Therapy II” sessions, Photonics West; January 24-29, 2004, San Jose, CA

Member International Program Committee of Saratov Fall Meeting - SFM'04, Workshop on Optical Technologies in Biophysics & Medicine VI, September 21 - 24, 2004, Saratov, Russia

Member Program Committee of SPIE International Conference of Optics in Health Care and Biomedical Optics: Diagnostics and Treatment II (PA104), Photonics Asia; and Chair, “Brain, Cancer, Molecular Beacons” and “Microscopy and Photonics Technology in Genomics and Proteomics of Cell I” sessions, November 8-12 November 2004, Beijing, China

Member Organizing / Technical Program Committee of Second Asian and Pacific Rim Symposium on Biophotonics (APBP), December 15-17, 2004, Taipei, Taiwan

Member Program Committee of SPIE International Conference of Laser Interaction with Tissue and Cells XVI; and Chair of Sessions “PDT I” and “PDT II”, Photonics West; January 22-27, 2005, San Jose, CA

Member Scientific Organizing Committee of The 4th Photonics and Imaging in Biology and Medicine - PIBM05,

and Chair, “Laser Interaction with Matter and Biological Materials” Session, September 3 - 6, 2005, Tianjin, China

Member International Program Committee of Saratov Fall Meeting - SFM'05, Workshop on Optical Technologies in Biophysics & Medicine VII, September 27 - 30, 2005, Saratov, Russia

Moderator Engineering Sciences Section, Oklahoma Academy of Science 94th Technical Meeting, November 5, 2005, Oklahoma City, Oklahoma

Chair SPIE International Conference of Biophotonics and Immune Responses; and Chair of Session “Photo-immune interactions”, Photonics West; January, 2006, San Jose, CA

Wei R. Chen, Ph.D.

Page 5 of 80

Member Program Committee of SPIE International Conference of Complex Dynamics and Fluctuations in Biomedical Photonics III, Photonics West; January, 2006, San Jose, CA

Member Executive Organizing Committee of SPIE International Symposium BiOS 2006 (Biomedical Optics), January, 2006, San Jose, CA

Member Program Committee of The 5th International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2006);

and Chair of Plenary Session V; September 1-3, 2006, Wuhan, China. Member International Program Committee of Saratov Fall Meeting - SFM'06, Workshop on

Optical Technologies in Biophysics & Medicine VIII, September 26 - 29, 2006, Saratov, Russia

Panelist Special Session “Laser in Surgery”, American College of Surgeons 92nd Annual Clinical Congress, October 10, 2006, Chicago, IL

Member Executive Organizing Committee of SPIE International Symposium BiOS 2007 (Biomedical Optics), January, 2007, San Jose, CA

Chair SPIE International Conference of Biophotonics and Immune Responses II; and Chair of Session “Photo-immune interactions”, Photonics West; January, 2007, San Jose, CA

Member Program Committee of SPIE International Conference of Complex Dynamics and Fluctuations in Biomedical Photonics IV, and Chair of Session “Dynamics of Laser Induced Nanoparticle Photothermolysis”, Photonics West; January, 2007, San Jose, CA

Member Program Committee of SPIE International Conference of Optical Interactions with Tissue and Cells XVIII; Photonics West; January, 2007, San Jose, CA

Member Scientific Committee, 11th World Congress on International Photodynamic Association; March 28-31, 2007, Shanghai, China

Member International Program Committee of Saratov Fall Meeting - SFM'07, Workshop on Optical Technologies in Biophysics & Medicine IX, September 25 - 28, 2007, Saratov, Russia

Member International Advisory Committee and Program Committee of International Conference Photonics Pacific Rim - Photonics and Imaging in Biology and Medicine (PIBM2007),

and Chair, Plenary Session II November 4-6, 2007, Wuhan, China Member Program Committee of SPIE International Conference of Optics in Health Care and

Biomedical Optics and Chair, “Light-tissue interaction and modeling” Session. Photonics Asia, November 11-15, 2007, Beijing, China Member Executive Organizing Committee of SPIE International Symposium BiOS 2008

(Biomedical Optics), January 19-24, 2008, San Jose, CA Chair SPIE International Conference of Biophotonics and Immune Responses III;

and Chair of Session “Monitoring Techniques”, Photonics West; January 21, 2008, San Jose, CA

Member Program Committee of SPIE International Conference of Complex Dynamics and Fluctuations in Biomedical Photonics V, Photonics West; January 19, 2008, San Jose, CA

Member International Program Committee of Saratov Fall Meeting - SFM'08, Workshop on Optical Technologies in Biophysics & Medicine X, September 23 - 26, 2008, Saratov, Russia

Wei R. Chen, Ph.D.

Page 6 of 80

Member Program Committee of 7th International Conference on Photonics and Imaging in Biology and Medicine (PIBM2008), November 24-27, 2008, Wuhan, China

Member Program Committee, Session “Laser Biomedical Diagnostics”, International Conference on Laser Applications in Life Sciences, December 4-6, 2008, Taipei, Taiwan

Member Executive Organizing Committee of SPIE International Symposium BiOS 2009 (Biomedical Optics), January 24-29, 2009, San Jose, CA

Member Program Committee of SPIE International Conference of Complex Dynamics and Fluctuations in Biomedical Photonics VI, and Chair of Session “Cell and Tissue Spectroscopy and Imaging” Photonics West; January 24, 2008, San Jose, CA

Chair SPIE International Conference of Biophotonics and Immune Responses IV; and Chair of Session “Detections of Photoimmune Activities”, Photonics West; January 26, 2009, San Jose, CA

Organizer - Secretary/Treasurer 7th Forum of Council of Chinese American Deans and Presidents (CCADP), January 30 – February 1, 2009, San Francisco, CA

Member International Advisory Committee and Program Committee of Symposium on Photonics and Optoelectronics (SOPO), August 23-25, 2009, Wuhan, China

Member Program Sub-Committee on “Laser Chemistry, Biophotonics and Applications” of The 8th Pacific Rim Conference on Lasers and Electro-Optics (CLEO/PR 2009), August 30 – September 3, 2009, Shanghai, China

Member International Program Committee of Saratov Fall Meeting - SFM'09, Workshop on Optical Technologies in Biophysics & Medicine XI, September 21-24, 2009, Saratov, Russia

Member International Program Committee of Saratov Fall Meeting - SFM'09, Workshop on Internet Biophotonics II, September 21-24, 2009, Saratov, Russia

Member Executive Organizing Committee of SPIE International Symposium BiOS 2010 (Biomedical Optics), January 23-28, 2010, San Francisco, CA

Member Program Committee of SPIE International Conference of Complex Dynamics and Fluctuations in Biomedical Photonics VI, Photonics West; January 23-28, 2010, San Francisco, CA

Chair SPIE International Conference of Biophotonics and Immune Responses V; and Chair of Session “Photoimmunotherapy: Pre-clinical”, Photonics West; January 23-28, 2010, San Francisco, CA

Organizer - Secretary/Treasurer 8th Forum of Council of Chinese American Deans and Presidents (CCADP), January 29 - 31, 2010, San Francisco, CA

Panelist and Invited Speaker The Sino-American Presidents and Deans Forum – Quality Assurance and Global Strategy in Higher Education, August 3, 2010, Shanghai, China

Member International Program Committee of Saratov Fall Meeting - SFM'10, Workshop on Optical Technologies in Biophysics & Medicine XII, October 5-8, 2010, Saratov, Russia

Member International Program Committee of Saratov Fall Meeting - SFM'10, Workshop on Internet Biophotonics III, October 5-8, 2010, Saratov, Russia

Member Program Committee of SPIE International Conference of Optics in Health Care and Biomedical Optics IV, Photonics Asia, October 18-20, 2010, Beijing, China


Member Executive Organizing Committee of SPIE International Symposium BiOS 2011 (Biomedical Optics), 22-27 January 2011, San Francisco, CA

Wei R. Chen, Ph.D.

Page 7 of 80

Member Program Committee of SPIE International Conference of Complex Dynamics and Fluctuations in Biomedical Photonics VII, Photonics West; 22-27 January 2011, San Francisco, CA

Chair SPIE International Conference of Biophotonics and Immune Responses VI; and Chair of Session “Photoimmunotherapy: Pre-clinical”, Photonics West; 22-27 January 2011, San Francisco, CA

Member International Program Committee of Saratov Fall Meeting - SFM'11, Workshop on Optical Technologies in Biophysics & Medicine XIII, September 27-30, 2011, Saratov, Russia

Member International Program Committee of Saratov Fall Meeting - SFM'11, Workshop on Internet Biophotonics IV, September 27-30, 2011, Saratov, Russia



Member Program Committee of SPIE International Conference of Complex Dynamics and Fluctuations in Biomedical Photonics VII, Photonics West; 21-26 January 2012, San Francisco, CA

Chair SPIE International Conference of Biophotonics and Immune Responses VII; and Chair of Session “Laser-Nanotechnology”, Photonics West; 21-26 January 2012, San Francisco, CA

Member Organizing Committee, Symposium “Cosmos, Cancer, Criticality and Chromoplasmology”, May 6, 2012, Seattle, WA

Member International Program Committee of Saratov Fall Meeting - SFM'12, Workshop on Optical Technologies in Biophysics & Medicine XIV, September 25-28, 2012, Saratov, Russia

Member International Program Committee of Saratov Fall Meeting - SFM'12, Workshop on Internet Biophotonics V, September 25-28, 2012, Saratov, Russia

Member Program Committee of SPIE International Conference of Optics in Health Care and Biomedical Optics V, Photonics Asia, November 4-7, 2012, Beijing, China

Member Executive Organizing Committee of SPIE International Symposium BiOS 2013 (Biomedical Optics), 2-7 February 2013, San Francisco, CA

Member Program Committee of SPIE International Conference of Complex Dynamics and Fluctuations in Biomedical Photonics IX, Photonics West; 2-7 February 2013, San Francisco, CA

Chair SPIE International Conference of Biophotonics and Immune Responses VIII, Photonics West; 4 February 2013, San Francisco, CA

Member Program Committee of 11th International Conference on Photonics and Imaging in Biology and Medicine (PIBM2013), May 26-29, 2013, Wuhan, China

Honorable Chair The 3rd Shanghai International Forum on Photodynamic Medicine, June 1-2, 2013, Shanghai, China

Lecturer The 3rd Shanghai International Forum on Photodynamic Medicine, June 1, 2013, Shanghai, China

Member International Program Committee of Saratov Fall Meeting - SFM'13, Workshop on Optical Technologies in Biophysics & Medicine XV, September 25-28, 2013, Saratov, Russia

Member International Program Committee of Saratov Fall Meeting - SFM'13, Workshop on Internet Biophotonics VI, September 25-28, 2013, Saratov, Russia

Wei R. Chen, Ph.D.

Page 8 of 80


Member Program Committee of SPIE International Conference of Complex Dynamics and Fluctuations in Biomedical Photonics X, Photonics West; 1-6 February 2014, San Francisco, CA

Chair SPIE International Conference of Biophotonics and Immune Responses IX; Photonics West; 1-6 February 2014, San Francisco, CA

Member International Program Committee of Saratov Fall Meeting - SFM'15, Optical Technologies in Biophysics & Medicine XVII, September 22-25, 2015, Saratov, Russia

Member International Program Committee of Saratov Fall Meeting - SFM'15, Internet Biophotonics VIII, September 22-25, 2015, Saratov, Russia


Member Program Committee of SPIE International Conference of Complex Dynamics and Fluctuations in Biomedical Photonics XI, Photonics West; 21-26 January 2015, San Francisco, CA

Chair SPIE International Conference of Biophotonics and Immune Responses X; Photonics West; 21-26 January 2015, San Francisco, CA

Member Program Committee of Track 5, Biophotonics and Optical Sensors, Asia Communication and Photonics Conference 2015 (ACP 2015), November 19-23, 2015, Hong Kong


Member Program Committee of SPIE International Conference of Complex Dynamics and Fluctuations in Biomedical Photonics XII, Photonics West; 13-18 February 2016, San Francisco, CA

Chair SPIE International Conference of Biophotonics and Immune Responses XI; Photonics West; 13-18 February 2016, San Francisco, CA

Journal Editing: Chair/Editor SPIE Proceedings Volume 6087 “Biophotonics and Immune Responses”, 2006 Chair/Editor SPIE Proceedings Volume 6438 “Biophotonics and Immune Responses II”, 2007 Chair/Editor SPIE Proceedings Volume 6857 “Biophotonics and Immune Responses III”, 2008 Chair/Editor SPIE Proceedings Volume 7178 “Biophotonics and Immune Responses IV”, 2009 Chair/Editor SPIE Proceedings Volume 7565 “Biophotonics and Immune Responses V”, 2010 Chair/Editor SPIE Proceedings Volume 7900 “Biophotonics and Immune Responses VI”, 2011 Chair/Editor SPIE Proceedings Volume 8224 “Biophotonics and Immune Responses VII”, 2012 Chair/Editor SPIE Proceedings Volume 8582 “Biophotonics and Immune Responses VIII”, 2013 Chair/Editor SPIE Proceedings Volume 8944 “Biophotonics and Immune Responses IX”, 2014 Chair/Editor SPIE Proceedings Volume 9324 “Biophotonics and Immune Responses X”, 2015 Chair/Editor SPIE Proceedings Volume 9709 “Biophotonics and Immune Responses XI”, 2016 Associate Editor Journal of X-Ray Science and Technology, 2004 – 2010 Editor-in-Chief Journal of X-Ray Science and Technology, 2011 – 2015 Member Editorial Board of Journal on Biomedical Photonics, 2007 – present Member Editorial Board of Journal of Innovative Optical Health Sciences (JIOHS), 2007 –

present Guest Editor Special Issue “Biophotonics”, 2002, Journal of X-Ray Science and Technology Ad Hoc Associate Editor Journal of Medical Physics, 2007 (MS #07-870)

Wei R. Chen, Ph.D.

Page 9 of 80

Journal Review: Reviewer Academic Radiology Reviewer Acta Pharmacologica Sinica Reviewer Annals of Biomedical Engineering Reviewer Apoptosis Reviewer Applied Optics Reviewer Applied Physics Letters Reviewer Biochemical and Biophysical Research Communications Reviewer Bioconjugate Chemistry (2014-04) Reviewer Biopolymers (2014-04) Reviewer Biosensors & Bioelectronics Reviewer Biotechnology Advances Reviewer Breast Cancer Research and Treatment Reviewer British Journal of Cancer Reviewer Cancer Immunology Immunotherapy Reviewer Cancer Letters Reviewer Cancer Research (2014-07) Reviewer Cell Cycle Reviewer European Journal of Cancer Reviewer IEEE Transactions on Biomedical Engine Reviewer IEEE Transactions on Education Reviewer Immunological Methods Reviewer International Journal of Cancer Reviewer International Journal of Hyperthermia Reviewer International Journal of Nanomedicine Reviewer Journal of Biomechanical Engineering – Transactions of ASME Reviewer Journal of Biomedical Optics Reviewer Journal of Biophotonics Reviewer Journal of Cellular Physiology Reviewer Journal of Innovative Optical Health Sciences Reviewer Journal of Photochemistry and Photobiology B: Biology Reviewer Journal of X-Ray Science and Technology Reviewer Lasers in Surgery and Medicine Reviewer Measurement Science and Technology Reviewer Medical and Biological Engineering and Computing Reviewer Medical Physics Reviewer Medicinal Research Reviews Reviewer Molecular and Cellular Biochemistry Reviewer Nanomedicine Reviewer Nanomedicine: Nanotechnology, Biology and Medicine Reviewer Nano Research Reviewer Nature Communications (2014-01, 2014-10) Reviewer Optical Engineering Reviewer Optics Express Reviewer Photochemistry and Photobiology Reviewer Physics D: Applied Physics Reviewer PLoS One

Wei R. Chen, Ph.D.

Page 10 of 80

Reviewer Proceedings of the National Academy of Science, U.S.A. Reviewer Review of Scientific Instruments Reviewer Sensors and Actuators: B. Chemistry Reviewer Vaccine Book Review: Reviewer Frontiers in Cancer Immunology: Cancer Immunotherapy, edited (Jianxun Song)

Bentham Science Publishers (Reviewed, August 2014) Grant Review: Reviewer 2005, Academic Research Fund Grant, National University of Singapore, Singapore Reviewer 2003, Arkansas Breast Cancer Research Program University of Arkansas for

Medical Sciences, Little Rock, Arkansas Reviewer 2007, Langston University biotechnology proposal, Langston University, Langston,

Oklahoma Panelist November 2009, National Science Foundation Review Panel for STEP grants,

Washington, DC Panelist November 2010, National Science Foundation Review Panel for STEP grants,

Washington, DC Mail Reviewer December 2009, National Institutes of Health, Vaccines Against Microbial Diseases

(VMD) Study Section Mail Reviewer December 2010, National Institutes of Health, Vaccines Against Microbial Diseases

(VMD) Study Section Ad hoc Reviewer March 2010, National Institutes of Health SBIR grant applications in “Development

and Translation of Medical Technologies that Reduce Health Disparities (SBIR [R43/R44]”

Reviewer December 2011, US Fulbright grant applications (Scholars from Taiwan to the US) Reviewer February 2012, US Fulbright grant applications (Scholars from the US to Taiwan) Reviewer September 2012, US Fulbright grant applications (Scholars from Russia to the US) Reviewer October 2012, National Institutes of Health, Special Emphasis Panel (SEP) BST-

U(91) – R15 AREA applications (gene/drug delivery and nanotechnology) Panelist January 2013, National Science Foundation Review Panel for STEP grants,

Washington, DC Member July 2014 to June 2017, US Fulbright Scholar Discipline Peer Review Committee -

Biomedical Engineering, Council for International Exchange of Scholars (CIES) HONORS AND AWARDS: International Awards Fellow of SPIE- The International Society for Optics and Photonics elected 2007 SPIE Educator Award - The International Society for Optics and Photonics 2012 National Awards National Institute of Health Summer Fellowship, Dept. of Physics, University of Oklahoma 1991 National Institute of Health Summer Fellowship, University of Oklahoma Health Center 1993

Wei R. Chen, Ph.D.

Page 11 of 80

Associated Western University Inc. Faculty Summer Research Fellowship, U. S. Department of Energy, Pittsburgh Energy Technology Center 1995 National Tandy Technology Prize for Science, Mathematics and Computer Science Teaching 1998 Selected as the Only Representative from Oklahoma (with Student Abdul Mohamed) to Present Research at “Posters on the Hill” in Washington, DC, April, 2007 US Professor of the Year (Outstanding Master’s Universities and Colleges Professor of the Year) 2008 Selected as the Only Representative from Oklahoma (with Student Henry Le) to Present Research at “Posters on the Hill” in Washington, DC, April, 2010 2011-2012 US Fulbright Lecturing / Research Award for Taiwan (September 1, 2011 to June 30, 2012) April 2011 State Awards Oklahoma DaVinci Fellows Award, Oklahoma 2006 Recognized for “High Level Teaching and Quality of Education” by Oklahoma State Senate Resolution No. 47 (52-1-1924), Sponsored by Senator Clark Jolley May 4, 2009 Selected as the Only Representative from the University of Central Oklahoma (with Student Henry Le) to Present Research at “Research Day at the Capitol” in Oklahoma City, Oklahoma, February, 2010 Selected as the Only Representative from the University of Central Oklahoma (with Student Kelvin Le) to Present Research at “Research Day at the Capitol” in Oklahoma City, Oklahoma, March, 2011 Winner of Medal for Excellence in Teaching, Oklahoma Foundation for Excellence (the highest teaching award in Oklahoma) May, 2011 University Awards Research Scholarship, Physics Department, University of Oregon 1983-1988 Faculty Merit-Credit Award (Research/Creative Activity Awards), Univ. of Central Oklahoma 2000 Faculty Research Grants/Publication Award, University of Central Oklahoma 2000 Faculty Research Grants/Publication Award, University of Central Oklahoma Spring, 2001 Faculty Research Grants/Publication Award, University of Central Oklahoma Fall, 2001 Faculty Merit-Credit Award (Teaching Activity Awards), University of Central Oklahoma 2001 Hauptman Fellowship Award, University of Central Oklahoma 2001 Sigma Xi Outstanding Research Award, UCO Chapter 2002 Faculty Research Grants/Publication Award, University of Central Oklahoma Spring, 2002 Faculty Merit-Credit Award (Research/Creative Activity Awards), Univ. of Central Oklahoma 2002 Faculty Research Grants/Publication Award, University of Central Oklahoma Fall, 2002 Distinguished Scholar Award of The University of Central Oklahoma Chapter of the American

Association of University Professors 2003 Faculty Merit-Credit Award (Teaching Activity Awards), University of Central Oklahoma Fall,

2003 Faculty Research Grants/Publication Award, University of Central Oklahoma Fall, 2003 Gold Faculty Merit-Credit Award (Research/Creative Activity Awards), Univ. of Central Okla. 2004 Faculty Merit-Credit Award (Service Activity Awards), Univ. of Central Okla. 2005 Faculty Merit-Credit Award (Research/Creative Activity Awards), Univ. of Central Okla. 2006 Faculty Research Grants/Publication Award, University of Central Oklahoma, Spring 2007 Vanderford Faculty Award in Support of Undergraduate Research, Creative and Scholarly Activities

University of Central Oklahoma, August 2007 Faculty Merit-Credit Award (Research/Creative Activity Awards), Univ. of Central Okla. 2008

Wei R. Chen, Ph.D.

Page 12 of 80

Neely Excellence in Teaching Award, Univ. of Central Okla. 2009 Faculty Merit-Credit Award (Research/Creative Activity Awards), Univ. of Central Okla. 2010 Faculty Merit-Credit Award (Research/Creative Activity Awards), Univ. of Central Okla. 2012 Faculty Merit-Credit Award (Research/Creative Activity Awards), Univ. of Central Okla. 2014 Inducted to the Inaugural Class of Luminary Society, Univ. of Central Okla. 2015 PATENTS ISSUED: 1. Robert E. Nordquist, Wei R. Chen, Raoul Carubelli, and Robert L. Adams, “Chitosan-Derived

Biomaterials”, United State Patent: 5,747,475 (Issued May 5 1998). 2. Robert E. Nordquist and Wei R. Chen, “Laser light delivery method”, United State Patent:

6,099,554 (Issued August 8, 2000). 3. Robert E. Nordquist, Robert L. Adams, Wei R. Chen, and Raoul Carubelli, “Cancer Treatment by

Photodynamic Therapy, in Combination with an Immunoadjuvant”, Australia Patent: 721276 (Issued October 12, 2000).

4. Robert E. Nordquist, Wei R. Chen, and Raoul Carubelli, “Laser/Sensitizer Assisted Immunotherapy”, United State Patent: 6,149,671 (Issued November 21, 2000).

5. Robert E. Nordquist, Wei R. Chen, and Raoul Carubelli, “Products in the Treatment of Cancer”, European Patent: 98920235.3-2116 (Issued March 5, 2001).

6. Robert E. Nordquist, Wei R. Chen, and Raoul Carubelli, “Laser/Sensitizer Assisted Immunotherapy”, United State Patent: 6,290,712 (Issued September 18, 2001).

7. Robert E. Nordquist, Wei R. Chen, and Raoul Carubelli, “Combined physical and immunotherapy for cancer”, United States Patent: 6,316,007 (Issued November 13, 2001).

8. Robert E. Nordquist, Wei R. Chen, Raoul Carubelli, and Robert L. Adams, “Cancer Treatment by Photodynamic Therapy, in Combination with an Immunoadjuvant”, Chinese Patent: ZL 961 94438.2 (Issued September 4, 2002).

9. Robert E. Nordquist, Wei R. Chen, Raoul Carubelli, and Robert L. Adams, “Cancer Treatment by Photodynamic Therapy in Combination with an Immunoadjuvant”, Japanese Patent: 3929491 (Issued March 23, 2003).

10. Fu-Jen Kao, Wei R. Chen, and Shin-Shian Lee, “Light Disinfection Device”, United States Patent: 8,614,426 (Issued December 24, 2013).

11. Wei R. Chen, “Immunologically Modified Carbon Nanotubes for Cancer Treatment”, United States Patent: 8,664,198 (Issued March 4, 2014).

12. Wei R. Chen, “Immunologically Modified Carbon Nanotubes for Cancer Treatment”, United States Patent: 9,107,944 (Issued August 18, 2015).

PATENT APPLICATION PUBLICATIONS: 13. Harvey Katz, Claudia Iovino, Stephey Bradway, Richard Iantosca, and Wei R. Chen, “Tire

Treatment Composition, Process and Packaging”, United States Patent Application Publication: 2007/0259990 (Published November 8, 2007)

14. Tomas Hode, Robert E. Nordquist, Wei R. Chen, Raoul Carubelli, Luciano Alleruzzo, Peter Jenkins, Kristopher Waynant, Joseph Raker, “Chitosan-Derived Compositions”, United States Patent Application Publication: 2015/0018748 (Published January 15, 2015).

PATENTS PENDING: 15. Wei R. Chen, “Immunologically Modified Carbon Nanotubes for Cancer Treatment”, submitted,

2013, European Union Patent, (Pending). Application No./Patent No.: 12752621.8 - 1651 PCT/US2012027021

Wei R. Chen, Ph.D.

Page 13 of 80

16. Robert E. Nordquist, Wei R. Chen, Raoul Carubelli, Tomas Hode, Kristopher, Waynant Hamilton, Luciano Alleruzzo, Peter Jenkins, “Chitosan-Derived Biomaterials and Applications Thereof”, submitted, 2011, US Patent, (Pending).

17. Wei R. Chen, Feifan Zhou, Zhifang Li, and Hui Li, "A device and a method for imaging-guided photothermal laser therapy for cancer treatment", US Patent, (pending).

AWARDED RESEARCH GRANTS:

AS PRINCIPAL INVESTIGATOR 1. Principal Investigator; “Photodynamic Immunotherapy for Metastatic Mammary Tumors”,

$173,600, May 1, 1996 to April 31, 1997, Xytronyx, Inc., San Diego, California. 2. Principal Investigator; “Photodynamic Immunotherapy: GLP Efficacy Studies, Treatment of

Prostate Cancer and Immunology Studies”, $72,050, July 1 1997 to Dec. 31, 1997, Pacific Pharmaceuticals, Inc., San Diego, California.

3. Principal Investigator; “Photodynamic Immunotherapy: Treatment of Prostate Cancer, and Immunology Studies II”, $39,270, April 1, 1998 to July 31, 1998, Pacific Pharmaceuticals, Inc., San Diego, California.

4. Principal Investigator; “Laser-Immunotherapy Treatment of Breast Cancer Using Different Immunoadjuvants”, $9,560, July 2000 to June 2001, University of Central Oklahoma.

5. Principal Investigator; “Role of Immunoadjuvants in Photo Dynamic Immuno Therapy”, $79,168, September 1 2000 to August 31, 2001, Oklahoma Center for the Advancement of Science and Technology (OCAST), $39,175 OCAST + $39,993 Industry Matching. (No. AR002-011P)

6. Principal Investigator; “Optimization and mechanistic studies of PDIT”, $583,247, February 1 2001 to January 31, 2004, Oklahoma Center for the Advancement of Science and Technology (OCAST), $290,315 OCAST + $292,932 Industry Matching. (No. AP01.1-016)

7. Principal Investigator; “Selective laser-photothermal interaction: Monte Carlo simulation and experimental determination of temperature distribution”, $5,830, July 2001 to June 2002, University of Central Oklahoma.

8. Principal Investigator; “Selective Photothermal Tissue Interaction using 805-nm Laser and Indocyanine Green in Tissue Welding”, $6,095, July 2002 to June 2003, University of Central Oklahoma.

9. Principal Investigator; “Immunological and photophysical interactions for cancers”, $250,958, 07/01/04 to 04/30/06, Institutional Development Award (IDeA) Networks of Biomedical Research Excellence (INBRE), National Center for Research Resources, National Institute of Health. (No.: P20RR016478-04).

10. Principal Investigator; “Evaluation of magnetic forces on superparamagnetic Fe304 nanoparticles”, $4,900, 05/01/06 to 06/01/06, Office of Navel Research (N00014-05-1-0385), subcontract.

11. Principal Investigator; Summer Student Program, $1,500, 05/2006 to 07/2006, Institutional Development Award (IDeA) Networks of Biomedical Research Excellence (INBRE).

12. Principal Investigator; “MRI-Guided Photoimmunotherapy”, $261,412, 12/01/06 to 04/30/09, IDeA Networks of Biomedical Research Excellence (INBRE) Grant, National Center for Research Resources, National Institute of Health (NIH). (No.: P20RR016478-06).



Wei R. Chen, Ph.D.

Page 14 of 80

15. Principal Investigator; $10,590/year, 05/2009 to present, College of Mathematics and Science CURE-STEM Scholarship, the University of Central Oklahoma.

16. Principal Investigator; “MRI-Guided Photoimmunotherapy”, $64,040, 05/01/2009 to 04/30/2010, IDeA Networks of Biomedical Research Excellence (INBRE) Grant, National Center for Research Resources, National Institute of Health (NIH). (No.: P20RR016478-09)

17. Principal Investigator; “STEM Double Bridge: Connecting High Schools, Community Colleges, and Universities for Tomorrow’s Leaders in Science, Technology, Engineering and Mathematics”, $1,998,750, 06/01/2009 to 05/31/2014, Science, Technology, Engineering, and Mathematics (STEM) Talent Expansion Program (STEP), National Science Foundation (NSF), (DUE-0856396).

18. Principal Investigator; “Support for High School Teachers in Summer Bridge Program”, $50,000, 06/01/2009 to 05/31/2014, Oklahoma EPSCoR.

19. Principal Investigator; “Therapeutic Evaluation of Magnetic Nanoprobes Specific for Malignant Tumor Markers”, $29,700, 05/01/2010 to 04/30/2011, NIH R21, (2 R21 CA136642-01A1), subcontract.

20. Principal Investigator; “Pre-Clinical Investigation of Nitrone Anti-Glioma Agent”, $25,000, 08/01/2009 to 07/31/2010, OCAST OARS (Project No. AR091-053), subcontract.

21. Principal Investigator; “Enhancing Laser Immunotherapy for Treatment of Metastatic Tumors by Reducing TGF-β Levels in Tumor Microenvironment”, $63,231, 04/01/2010 to 03/31/2011, IDeA Networks of Biomedical Research Excellence (INBRE) Grant, National Center for Research Resources, National Institute of Health (NIH). (No.: P20RR016478-10).

22. Principal Investigator; “Release Time for Curriculum Development or Grant Proposal Development”, $26,142, 01/2010 to 05/2010, The Oklahoma State Regents for Higher Education.


24. Principal Investigator; “Interstitial laser immunotherapy for treatment of deep tumors”, $21,044, 08/10/2010 to 01/31/2011, ImmunoPhotonics, Inc., Columbia, MO.

25. Principal Investigator; Equipment grant application, $15,000, 05/2010 to 10/2010, Institutional Development Award (IDeA) Networks of Biomedical Research Excellence (INBRE).

26. Principal Investigator; “Laser-Nanotechnology for Cancer Treatment”, $7,000, 08/01/2011 to 01/31/2012, ImmunoPhotonics, Inc., Columbia, MO.


28. Principal Investigator; “A Novel Multifunctional Bionanoprobe-Based Phototherapy for Metastatic Cancers”, $349,596, 08/01/2013 to 07/31/2015, NIH National Institute of Biomedical Imaging and Bioengineering (NIBIB). (No. 1 R21 EB 015509-01-A1).

29. Principal Investigator; “Fulbright Visiting Scholar Program for Iraq”, $117,000, 06/01/2014 to 09/31/2014, Council for International Exchange of Scholars, Institute of International Education.

30. Principal Investigator; “Antitumor Effect of Hemp Oil”, $10,000, 08/01/2014 to 07/31/2016, Earth Science Tech, Inc., Boca Raton, FL.

31. Principal Investigator; “Cellular immunological responses induced by glycated chitosan”, $25,000, 01/01/2015 to 12/31/2016, ImmunoPhotonics, Inc., St. Louis, MO.

32. Principal Investigator; “Fulbright Visiting Scholar Program for Iraq”, $72,500, 06/01/2015 to 09/31/2015, Council for International Exchange of Scholars, Institute of International Education.

Wei R. Chen, Ph.D.

Page 15 of 80

33. Principal Investigator; Equipment grant application, $25,000, 05/2015 to 04/2016, Institutional Development Award (IDeA) Networks of Biomedical Research Excellence (INBRE).


35. Principal Investigator; Conference Travel Grant, $2,000, 01/2016 to 07/2016, Institutional Development Award (IDeA) Networks of Biomedical Research Excellence (INBRE).

36. Principal Investigator; “Effects of interstitial inCVAX for the treatment of metastatic tumors in rats”, $71,000, 09/2015 to 12/2016, BioGenerator, St. Louis, MO.

AS CO-PRINCIPAL INVESTIGATOR 1. Co-Principal Investigator; “Laser Immunotherapy for the Treatment of Cancer in Man and

Animals”; $39,970 (direct cost); June 1998 to May 1999; Puterbaugh Foundation, McAlester, Oklahoma.

2. Co-Principal Investigator; “Photodynamic therapy and photothermal coagulation for selective treatment of cancer and other pathologic conditions”, $225,000 (direct cost); June 1999 to May 2001; Presbyterian Foundation, McAlester, Oklahoma.

3. Co-Principal Investigator; “Laser Immunotherapy in Treatment of Metastatic Prostate Tumors”, $9,932 (direct cost); July 1999, to June 2000; University of Central Oklahoma.

4. Co-Principal Investigator; “Phase I clinical trial of chromophore-enhanced laser-induced hyperthermia”, $36,575, (direct cost); January 2001 to December 2001; Barbour Foundation, Oklahoma.

5. Co-Principal Investigator; “Mechanisms of low intensity laser irradiation stimulation of wound healing”, $134,488, (direct cost); 7/01/02 to 6/30/05, Oklahoma Center for the Advancement of Science and Technology (OCAST HR02-153RS).

6. Co-Principal Investigator; “Indocyanine Green and Immunoadjuvant in Selective Hyperthermia for Treatment of Mouse Melanoma”, $19,036, (direct cost); 06/01/03 to 12/31/03, Barbour Foundation, Oklahoma.

7. Co-Principal Investigator; “Photodynamic Therapy in Combination with Chemotherapy and Immunotherapy for Treatment of Metastatic Mammary Rat Tumors”, $26,998 (direct cost); 06/01/03 to 12/31/03, Kleberg Foundation, Oklahoma.

8. Co-Principal Investigator; “A dual detector technique for x-ray attenuation and phase imaging”, $1,782,908, 10/01/2003 to 09/30/2007, National Institute of Health (NIH/NIBIB) (No.: R01 EB002604).

9. Co-Principal Investigator; “Phase contrast x-ray imaging with a field emission source”, $1,672,013, 12/1/2003-11/30/2007, National Institute of Health (NIH/NCI) (No.: R01 CA104773).

10. Co-Principal Investigator; “Center for Undergraduate Research & Education Student Scholars in Science, Technology, Engineering, and Mathematics”, $600,000, 06/01/2010 to 05/31/2015, S-STEM Program, National Science Foundation (NSF), (DUE-0965864).

EDUCATION PROGRAMS PROPOSED AND DEVELOPED: 1. Biomedical Engineering undergraduate degree program (University of Central Oklahoma)

Developed: 1999 to 2000 Proposed: fall, 2000 Approved: December 2000, by Oklahoma State Regents for Higher Education

Wei R. Chen, Ph.D.

Page 16 of 80

COURSES PROPOSED: 1. Principle of Biomedical Engineering I (University of Central Oklahoma), Fall, 2000 2. Principle of Biomedical Engineering II (University of Central Oklahoma), Fall, 2000

COURSES DEVELOPED: 1. Medical Physics (University of Central Oklahoma), 1996 and 1997 (revised and developed) 2. Medical Physics Lab (University of Central Oklahoma), 1996 and 1997 (revised and

developed) 3. Modern Physics Lab (University of Central Oklahoma), Fall 1999 and 2000 4. Principle of Biomedical Engineering I (University of Central Oklahoma), Fall, 2002 5. Principle of Biomedical Engineering II (University of Central Oklahoma), Spring, 2003 COURSES TAUGHT: 1. Physical Science 2. General Physics 3. Engineering Physics 4. General Physics I 5. Mechanics (calculus based) 6. Electricity and Magnetism (calculus based) 7. Modern Physics 8. Modern Physics Lab 9. Introduction to Modern Physics 10. Modern Physics II 11. Mathematics (Algebra for college freshmen) 12. Medical Physics 13. Medical Physics Lab 14. Semiconductor (Graduate Course) 15. Mathematical Physics I 16. Quantum Mechanics 17. Principles of Biomedical Engineering I 18. Principles of Biomedical Engineering II 19. Biomedical Imaging 20. Classical Mechanics 21. Electromagnetic Fields II OTHER WORK EXPERIENCE: 1. Teacher Trainer (for high school teachers) for Mechanical Universe High School Adaptation,

certified by National Diffusion Network 1989-1999 2. Member, Panel for Oklahoma State Regents for Higher Education Reviewing and Evaluating grant proposals for Summer Academies for Mathematics, Science, and

Multidisciplinary Studies 1993-1999 3. Member, Panel for Oklahoma State Regents for Higher Education Reviewing and Evaluating grant proposals for Dwight D. Eisenhower Mathematics and Science

Education Program (Title II Grant) 1994-1999

Wei R. Chen, Ph.D.

Page 17 of 80

UNIVERSITY SERVICE AT UNIVERSITY OF CENTRAL OKLAHOMA: Department of Engineering and Physics 1. 1999-2015 Member Graduate Program Committee, Department of Physics and Engineering,

University of Central Oklahoma 2. 2000-2001 Chair Committee for Biomedical Engineering program, Department of Physics

and Engineering, University of Central Oklahoma 3. 1999-2006 Member Curriculum Committee, Biomedical Engineering Department of Physics

and Engineering, University of Central Oklahoma 4. 2000-2006 Member Recruitment and Retention Committee, Department of Physics and

Engineering, University of Central Oklahoma 5. 2000-2006 Director Biomedical Engineering Program, Department of Physics and

Engineering, University of Central Oklahoma 6. 2001-2002 Member Task Force on Accreditation Board for Engineering and Technology

(ABET), Department of Physics and Engineering, University of Central Oklahoma

7. 2001-2002 Chair Curriculum Committee, Department of Physics and Engineering, University of Central Oklahoma

8. Fall, 2002 Member Faculty Promotion Committee, Department of Physics and Engineering, University of Central Oklahoma

9. 2003-2004 Member Faculty Search Committee, Department of Physics and Engineering, University of Central Oklahoma

10. Spring, 2004 Member Development of Chairperson’s Evaluation Tool Committee, Department of Physics and Engineering, University of Central Oklahoma

11. Fall, 2004 Member Schedule Committee, Department of Physics and Engineering, University of Central Oklahoma

12. Fall, 2004 Member Budget Committee, Department of Physics and Engineering, University of Central Oklahoma

College of Science and Mathematics 1. 1999-2000 Member Task Force for Biomedical Engineering program, College of

Mathematics and Science, University of Central Oklahoma 2. 2001-2003 Member Curriculum Committee, College of Mathematics and Science, University

of Central Oklahoma 3. 2004 Member Task Force for Rothbaum Scholarship, College of Mathematics and

Science, University of Central Oklahoma 4. 2005-2006 Member College Promotion Committee, College of Mathematics and Science,

University of Central Oklahoma University of Central Oklahoma 1. 1999-2002 Liaison Research Advisory Council, University of Central Oklahoma 2. 2001-2005 Member Task Force on Globalization, University of Central Oklahoma 3. 2003-2005 Member Faculty Senate, University of Central Oklahoma 4. 2004-2007 President-Elect, President, Past-President Sigma Xi, UCO Chapter 5. 2004-2005 Chair Faculty Senate Faculty Welfare & Development Committee, University

of Central Oklahoma 6. 2004-2005 Member Faculty Senate Faculty Adjunct Affairs Committee, University of

Central Oklahoma

Wei R. Chen, Ph.D.

Page 18 of 80

7. 2004-2005 Member Faculty Senate Faculty Information Resources Committee, University of Central Oklahoma

8. 2004-2005 Member Faculty Senate Faculty Technology Committee, University of Central Oklahoma

9. 2006-2008 Member Retention Committee, University of Central Oklahoma 10. 2008-2010 Member Passport UCO, Planning Committee, University of Central Oklahoma 11. 2006-2009 Campus and Program Coordinator, National Science Foundation (NSF) SURE-

STEP Program (Supporting Undergraduate Research and Education for the Science, Technology, Engineering, and Mathematics Talent Expansion Program), University of Central Oklahoma

12. 2011-2013 President-Elect, President, Past-President Sigma Xi, UCO Chapter 13. 2012-Present Faculty Mentor, For UCO new faculty member, Mark Janzen PROFESSIONAL SOCIETY SERVICE 1. 2004-2006 Member Ph.D. Committee for Surya C. Gnyawali, Department of Physics,

Oklahoma State University 2. 2004-2006 Advisor Ph.D. thesis, Surya C. Gnyawali, Department of Physics, Oklahoma

State University 3. 2007-present Member Ph.D. Committee for Zhen Jiang, School of Electrical & Computer

Engineering, Oklahoma State University 4. 2007-2009 Member Education Committee of SPIE – The International Society for Optics and

Photonics 5. 2009-2010 Member Fellows Committee of SPIE – The International Society for Optics and

Photonics 6. 2015-2017 Member Educator Award Committee of SPIE – The International Society for

Optics and Photonics COMMUNITY SERVICE 1. December 11, 2007 Speaker BME program in US and in Oklahoma, Norman High

School 2. September 27, 2007 Host College of Mathematics and Science Seminar Series, Dr.

Robert Nordquist presentation “Cancer Cell Defense Mechanism”. 3. September 24, 2008 Speaker “Challenges in Phototherapy for Cancer”, Presentation to

Saratov High School Math-Physics Students, Saratov, Russia.

Wei R. Chen, Ph.D.

Page 19 of 80

WORKING WITH PEOPLE HOST FOR VISITING SCHOLARS TO UCO 1. S. Winkins Santosh, PhD, Assistant Professor (Sr.G),

Department of Biotechnology, School of Bioengineering SRM University, Kattankulathur- 603203, Tamilnadu,India. Visiting Time: February to March 2009

Topic: Laser induced immunological responses 2. Xiaosong Li, MD/PhD, Attending Physician

Department of Oncology and Department of Laser Medicine The First Affiliated Hospital of Chinese PLA General Hospital, Beijing 100048, China Visiting Time: February to September 2009; March 2010 to October 2010

Topic: Laser immunotherapy for metastatic cancers MENTOR TO JUNIOR FACULTY 1. Mohamed Bingabr, Ph.D.

Assistant Professor Department of Physics and Engineering 2005 to 2007

RESEARCH ASSOCIATE ADVISOR: 1. Yichao Chen, Ph.D.

Department of Engineering and Physics, University of Central Oklahoma The first post-doctoral full-time research associate in the University of Central Oklahoma February 2005 – May 2008

2. Okhil Kumar Nag, Ph.D.

Department of Engineering and Physics, University of Central Oklahoma May 2011 – December 2011

3. Feifan Zhou, Ph.D. Department of Engineering and Physics, University of Central Oklahoma January 2014 – present

PH.D. THESIS ADVISOR:

1. Surya C. Gnyawali Department of Physics, Oklahoma State University Title: Study of Tissue Temperature Distribution during Laser-Immunotherapy for Cancer Treatment Starting Data: March 2004 Graduate Date: May 2007

2. Lei Liu

Institute of Laser Life Science South China Normal University

Wei R. Chen, Ph.D.

Page 20 of 80

Guangzhou, China Title: PDT induced apoptosis in cancer treatment Starting Data: August 2005

Graduate Date: June 2009

3. Feifan Zhou Institute of Laser Life Science South China Normal University

Guangzhou, China Title: Study on the regulation mechanism of immune response and the application under tumor

laser immunotherapy Starting Data: August 2006

Graduate Date: June 2010 MASTER’S THESIS ADVISOR: 1. Sang Won Jeong

Department of Engineering and Physics, University of Central Oklahoma Title: Selective Photothermal Interaction of Laser-Irradiated Tissue in Cancer Treatment Starting Date: August 2001 Graduation Date: May 2003

2. HemanthKumar Athiraman Department of Engineering and Physics, University of Central Oklahoma Title: Near-Infrared Laser and Laser-Absorbing Dye in Tissue Welding Starting Date: January 2002 Graduation Date: May 2003

3. Jeremy Bjorlie Department of Engineering and Physics, University of Central Oklahoma Title: MRI in Biomedical Engineering Research Starting Date: January 2005 Transferred to the University of Oklahoma August 2005

4. Akhee Sarker Department of Engineering and Physics, University of Central Oklahoma Title: MRI in Laser Cancer Treatment Starting Date: January 2008 Graduation Date: August 2009

5. Chet Joshi Department of Engineering and Physics, University of Central Oklahoma Title: Photothermal Effects in Laser Cancer Treatment Starting Date: August 2010 Graduation Date: December 2011

UNDERGRADUATE / GRADUATE STUDENT RESEARCH ADVISOR: 1. Andrea K. Ives, Undergraduate Student

Department of Engineering and Physics, University of Central Oklahoma Project: A Novel Treatment Method for Metastatic Tumors Time: August 1999 to May 2000

2. Ahmad El-Samad, Undergraduate Student Department of Chemistry, University of Central Oklahoma

Wei R. Chen, Ph.D.

Page 21 of 80

Project: Laser-Dye-Immunoadjuvant Treatment of Prostate Tumor in Rats Time: August 1999 to May 2000

3. Sarah Kimball, Undergraduate Student Department of Chemistry, University of Central Oklahoma Project: Laser Cancer Treatment Time: August 2000 to May 2001

4. Shawn L. Baker, Graduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Photo Dynamic Immunotherapy with Different Immunoadjuvants Time: August 2000 to May 2001

5. Jeremy Real, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Cancer Treatment Using Laser and Dye Time: August 2001 to May 2002

6. Christopher Bailey, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Monte Carlo Simulation of Laser Photothermal Tissue Interaction Time: January 2002 to May 2003

7. Jared Crochet, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Laser Photothermal Tissue Interaction Time: August 2002 to July 2004

8. Tiffany Thoren, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Laser Cancer Treatment Time: January 2003 to May 2004

9. Kirill Andrienko, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Laser-Immunotherapy Cancer Treatment Time: June 2003 to May 2005

10. Suman Shivakoti, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Thermal Properties and Laser Cancer Treatment Time: June 2003 to May 2005

11. Amir Isbell, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Biological Tissue Strength Time: January 2005 to May 2006

12. Yassir Janah, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: MRI in Biomedical Engineering Research Time: January 2005 to May 2006

13. Jeremy Bjorlie, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: MRI in Biomedical Engineering Research Time: August 2003, to January 2005

14. Ademola Adeyemi, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma

Wei R. Chen, Ph.D.

Page 22 of 80

Project: Thermal Effect in Laser Tissue Interaction Time: July 2005 to May 2007

15. Jennifer Ellis, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Laser Immunotherapy for Cancer Treatment Time: July 2006 to June 2008

16. Chris Bobo, Undergraduate Students Department of Engineering and Physics, University of Central Oklahoma Project: Laser Immunotherapy for Cancer Treatment Time: July 2006 to June 2009

17. Gaurav Kumar, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Thermal Effect in Laser Tissue Interaction Time: July 2006 to May 2007

18. Abdiwahab “Adbul” Mohamed, Undergraduate Student Department of Chemistry, University of Central Oklahoma Project: Immunological Effects of Laser Treatment of Cancer Time: June 2006 to May 2007

19. Henry Le, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Thermal Effect in Laser Tissue Interaction Time: March 2007 to May 2010

20. Halie Ferguson, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Comparison of Different Tumor Treatment Methods – Surgery versus Laser Treatment Time: August 2007 to May 2010

21. Kelvin Le, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: MR Imaging Analysis for Laser-Tissue Interaction Time: August 2007 to May 2011

22. Temesha Brown, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Biomedical Engineering Instrumentation Time: August 2007 to July 2008

23. Chet Joshi, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Laser Treatment of Animal Tumors Time: January 2008 to August 2010

24. Bailee Loftis, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Laser Immunotherapy for Cancer Treatment Time: August 2008 to May 2009

25. Christian Oliphant, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Laser Immunotherapy for Cancer Treatment Time: August 2008 to May 2009

26. Daniel Figueroa, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma

Wei R. Chen, Ph.D.

Page 23 of 80

Project: MRI Monitoring of Thermal Effect Time: August 2008 to May 2011

27. KC Denney, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: MRI Monitoring of Thermal Effect Time: August 2008 to May 2009

28. Moones Akbaran, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: MRI in Biomedical Applications Time: November 2008 to May 2009

29. Amanda Walker, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Laser Cancer Treatment Time: August 2009 to May 2011

30. Jonny Walla, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Laser Cancer Treatment Time: August 2009 to May 2011

31. Long Nguyen, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Laser Cancer Treatment Time: August 2009 to May 2011

32. Toney Stacy, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Laser Cancer Treatment Time: August 2009 to May 2011

33. Katherine Kastl, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Laser Cancer Treatment Time: August 2010 to May 2012

34. Jessnie Jose, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Laser Cancer Treatment Time: August 2010 to May 2012

35. Jessica Goddard, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Laser Cancer Treatment Time: August 2010 to May 2012

36. Mallory Martin, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Laser Cancer Treatment Time: August 2010 to May 2012

37. Destiny Brown, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Laser Cancer Treatment Time: August 2010 to May 2012

38. Sean Pontius, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma

Wei R. Chen, Ph.D.

Page 24 of 80

Project: Laser Cancer Treatment Time: August 2010 to May 2012

39. Joseph Acquaviva, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Laser-Nanotechnology for Cancer Treatment Time: January 2011 to May 2014

40. Allie Sikes, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Laser Effects on Biomechanical Properties of Cells Time: August 2012 to May 2014

41. Cody Bahavar, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Fluid Dynamics of Glycated Chitosan and Laser Cancer Treatment Time: August 2012 to present

42. Ellen Boarman, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Laser Cancer Treatment Time: August 2012 to May 2014

43. Keegan Phillips, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Fluid Dynamics of Glycated Chitosan and Laser Cancer Treatment Time: August 2012 to May 2014

44. Zachary Burton, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Laser Effects on Biomechanical Properties of Cells Time: August 2012 to May 2014

45. Brock Henderson, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Laser Cancer Treatment Time: August 2012 to May 2014

46. Erica Halterman, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Laser Cancer Treatment Time: August 2012 to May 2015t

47. Aamr Hasanjee, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Laser Immunotherapy for Cancer Treatment Time: August 2013 to present

48. Sheyla Rabie, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Laser Immunotherapy for Cancer Treatment Time: August 2013 to present

49. Weston Schloss, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Laser Immunotherapy for Cancer Treatment Time: August 2013 to December 2013

50. Bailey Vasquez, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma

Wei R. Chen, Ph.D.

Page 25 of 80

Project: Laser Immunotherapy for Cancer Treatment Time: August 2013 to May 2014

51. Ethan Wood, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Laser Immunotherapy for Cancer Treatment Time: August 2013 to present

52. Elivia Layton, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Project: Laser Immunotherapy for Cancer Treatment

Time: December 2013 to present 53. Austin Doughty, Undergraduate Student

Department of Engineering and Physics, University of Central Oklahoma Project: Laser Immunotherapy for Cancer Treatment

Time: August 2014 to present 54. Connor West, Undergraduate Student


Time: August 2014 to present 55. Chante Preston, Undergraduate Student


Time: August 2014 to December 2014 56. Marissa Buller, Undergraduate Student


Time: August 2014 to present 57. Caleb Mohr, Undergraduate Student


Time: August 2014 to present 58. Payden Cloud, Undergraduate Student


Time: August 2014 to present 59. Prayus Barua, Undergraduate Student


Time: August 2015 to present 60. Blake Young, Undergraduate Student


Time: August 2015 to present 61. Brittani Kellogg, Undergraduate Student


Time: August 2015 to present 62. Kegan Silk, Undergraduate Student

Department of Engineering and Physics, University of Central Oklahoma

Wei R. Chen, Ph.D.

Page 26 of 80

Project: Laser Immunotherapy for Cancer Treatment Time: August 2015 to present 63. Caleb Shaw, Undergraduate Student


Time: August 2015 to present 64. Darian Lincoln, Undergraduate Student


Time: August 2015 to present 65. Alex Pettitt, Undergraduate Student


Time: August 2015 to present STUDENT INTERNSHIP COORDINATOR / ADVISOR: 1. Fadee Mondelek, Undergraduate Student

January 2003 to May 2003 Department of Engineering and Physics, University of Central Oklahoma Internship: University of Oklahoma Health Science Center Project: Magnetic Nanoparticle in Drug Delivery

4. Kirill Andrienko, Undergraduate Student May 2004 to August 2004 Department of Engineering and Physics, University of Central Oklahoma Internship: ForHealth Technologies, Inc., Daytona Beach, FL Project: Automation in Drug Delivery and Health Care

5. Moatez Eldib, Undergraduate Student June 2004 to August 2004 Department of Engineering and Physics, University of Central Oklahoma Internship: The Samuel Roberts Noble Foundation, Inc., Ardmore, Oklahoma Project: DNA and Gernomics

6. Natessa C. Riley, Undergraduate Student January 2005 to August 2005 Department of Engineering and Physics, University of Central Oklahoma Internship: The Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma Project: Biomedical Technology in Research

7. Arinze “Ike” Abiakam, Undergraduate Student January 2005 to August 2005 Department of Engineering and Physics, University of Central Oklahoma Internship: The NanoBioMagnetics, Inc, Edmond Oklahoma Project: Biomedical Magnetic Nanoparticles

STUDENT INDEPENDENT STUDY / PROJECT SUPERVISOR: 1. Mekhala Desikachar, Graduate Student

Department of Engineering and Physics, University of Central Oklahoma Title: Directed Study in Biomedical Engineering Topics: Design and development of digital thermal meter and electrocardiograph device

Wei R. Chen, Ph.D.

Page 27 of 80

Time: August 2002 to May 2003 2. Micah Bell, Undergraduate Student

Department of Engineering and Physics, University of Central Oklahoma Title: Directed Study in Biomedical Engineering Topics: Applications of Lasers in Biomedical Research Time: August 2002 to May 2003

3. Fadee Mondelek, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Title: Biomedical Ethics Project: Term Paper: Animal Use in Biomedical Research Time: January 2003 to May 2003

4. Zachary M. Smith, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma Title: Biomedical Ethics Project: Term Paper: Patient Privacy Time: January 2004 to May 2004

5. Stella Onyeri, Senior Design, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma School of Chemical Engineering, Oklahoma State University Project Title: Design of Chitosan-Gelatin Scaffolds for Tissue Engineering Time: August 2007 to May 2008

6. Kelvin Le, Senior Design, Undergraduate Student Department of Engineering and Physics, University of Central Oklahoma

Project Title: Laser light delivery system for medical applications Time: August 2010 to May 2011 7. Kajal Jassemnejad, Senior Design, Undergraduate Student

Department of Engineering and Physics, University of Central Oklahoma Project Title: Laser light delivery system for medical applications Time: August 2010 to May 2011 8. Henry Le, Senior Design, Undergraduate Student

Department of Engineering and Physics, University of Central Oklahoma Project Title: Laser light delivery system for medical applications Time: August 2010 to May 2011 9. Kendal Wilsey, Senior Design, Undergraduate Student

Department of Engineering and Physics, University of Central Oklahoma Project Title: Laser light delivery system for medical applications Time: August 2010 to May 2011 10. Lance Straughn, Senior Design, Undergraduate Student

Department of Engineering and Physics, University of Central Oklahoma Project Title: Temperature Data Logger and Control System

Time: August 2012 to May 2013 11. Shayla Pearson, Senior Design, Undergraduate Student


Time: August 2012 to May 2013 12. Amanda Walker, Senior Design, Undergraduate Student


Wei R. Chen, Ph.D.

Page 28 of 80

Time: August 2012 to May 2013 SUMMER STUDENT RESEARCH ADVISOR: 1. Thomas Cowan, Undergraduate Student

Department of Biomedical Engineering, University of Southern California Los Angeles, California Project: Selective Photothermal Interaction in Cancer Treatment Time: Summer 2001 Place: D Department of Engineering and Physics, University of Central Oklahoma

2. Thomas Cowan, Medical School Student (Ph.D./M.D. Program) Medical School, Case Western Reserve University Cleveland, Ohio Project: Selective Photothermal Interaction in Cancer Treatment Time: Summer 2002 Place: Department of Engineering and Physics, University of Central Oklahoma

3. Vinson Liu, Undergraduate Student Department of Computer Engineering, The Johns Hopkins University Baltimore, Maryland Project: Computer Simulation of Selective Photothermal Interaction Time: Summer 2001

4. Vinson Liu, Undergraduate Student Department of Computer Engineering, The Johns Hopkins University Baltimore, Maryland Project: Computer Simulation of Selective Photothermal Interaction Time: Summer 2002 Place: Department of Engineering and Physics, University of Central Oklahoma

5. Vinson Liu, Undergraduate Student Department of Computer Engineering, The Johns Hopkins University Baltimore, Maryland Project: Computer Simulation of Selective Photothermal Interaction Time: Summer 2003

6. Dan Stark, Undergraduate Student Department of Physics, University of Oklahoma Norman, Oklahoma Project: Laser-Tissue Interaction Time: Summer 2001 Place: Department of Engineering and Physics, University of Central Oklahoma

7. Sarah Simmons, Undergraduate Student Department of Biomedical Engineering, Massachusetts Institute of Technology Boston, Massachusetts Project: Selective Photothermal Laser-Tissue Interaction Time: Summer 2001 Place: Department of Engineering and Physics, University of Central Oklahoma

8. Elisa N. Shoate, Undergraduate Student University of Central Oklahoma SURE-Summer Bridge Student Project: Laser Cancer Treatment

Wei R. Chen, Ph.D.

Page 29 of 80

Time: Summer 2006 Place: Department of Engineering and Physics, University of Central Oklahoma

9. Kandace N. Metcalf, Undergraduate Student University of Central Oklahoma SURE-Summer Bridge Student Project: Laser Cancer Treatment Time: Summer 2006 Place: Department of Engineering and Physics, University of Central Oklahoma

10. Kim D. Sookbang, Undergraduate Student University of Central Oklahoma SURE-Summer Bridge Student Project: Laser Cancer Treatment Time: Summer 2006 Place: Department of Engineering and Physics, University of Central Oklahoma

11. Novella Peyton, Undergraduate Student University of Central Oklahoma SURE-Summer Bridge Student Project: Laser Cancer Treatment Time: Summer 2006 Place: Department of Engineering and Physics, University of Central Oklahoma

12. Chris D. Bobo Jr, Undergraduate Student University of Central Oklahoma SURE-Summer Bridge Student Project: Laser Cancer Treatment Time: Summer 2006 Place: Department of Engineering and Physics, University of Central Oklahoma

13. Jenifer A. Ellis, Undergraduate Student University of Central Oklahoma SURE-Summer Bridge Student Project: Laser Cancer Treatment Time: Summer 2006 Place: Department of Engineering and Physics, University of Central Oklahoma

14. Deon Peoples, Undergraduate Student University of Central Oklahoma SURE-Summer Bridge Student Project: Laser Photothermal Effect in Cancer Treatment Time: Summer 2007 Place: Department of Engineering and Physics, University of Central Oklahoma

15. Halie Ferguson, Undergraduate Student University of Central Oklahoma SURE-Summer Bridge Student Project: Laser Photothermal Effect in Cancer Treatment Time: Summer 2007 Place: Department of Engineering and Physics, University of Central Oklahoma

16. JP Cooper, Undergraduate Student University of Central Oklahoma SURE-Summer Bridge Student Project: Laser Photothermal Effect in Cancer Treatment

Wei R. Chen, Ph.D.

Page 30 of 80


17. Kelvin Le, Undergraduate Student University of Central Oklahoma SURE-Summer Bridge Student Project: Laser Photothermal Effect in Cancer Treatment Time: Summer 2007 Place: Department of Engineering and Physics, University of Central Oklahoma

18. Savanna White, Undergraduate Student University of Central Oklahoma SURE-Summer Bridge Student Project: Laser Photothermal Effect in Cancer Treatment Time: Summer 2007 Place: Department of Engineering and Physics, University of Central Oklahoma

19. Tamesha Brown, Undergraduate Student University of Central Oklahoma SURE-Summer Bridge Student Project: Laser Photothermal Effect in Cancer Treatment Time: Summer 2007 Place: Department of Engineering and Physics, University of Central Oklahoma

20. Bailee Loftis, Undergraduate Student University of Central Oklahoma SURE-Summer Bridge Student Project: Laser Immunotherapy for Cancer Treatment Time: Summer 2008 Place: Department of Engineering and Physics, University of Central Oklahoma

21. Christian Oliphant, Undergraduate Student University of Central Oklahoma SURE-Summer Bridge Student Project: Laser Immunotherapy for Cancer Treatment Time: Summer 2008 Place: Department of Engineering and Physics, University of Central Oklahoma

22. Daniel Figueroa, Undergraduate Student University of Central Oklahoma SURE-Summer Bridge Student Project: MRI Monitoring of Thermal Effect Time: Summer 2008 Place: Department of Engineering and Physics, University of Central Oklahoma

23. KC Denney, Undergraduate Student University of Central Oklahoma SURE-Summer Bridge Student Project: MRI Monitoring of Thermal Effect Time: Summer 2008 Place: Department of Engineering and Physics, University of Central Oklahoma

24. Stephanie Capson, Undergraduate Student University of Central Oklahoma SURE-Summer Bridge Student Project: MRI Monitoring of Thermal Effect

Wei R. Chen, Ph.D.

Page 31 of 80


25. Amanda Walker, Undergraduate Student University of Central Oklahoma STEP Summer Bridge Student Project: Monitoring Temperature Increase in Gel Phantom and Tissue during Laser Irradiation Time: Summer 2009 Place: Department of Engineering and Physics, University of Central Oklahoma

26. Jonny Walla, Undergraduate Student University of Central Oklahoma STEP Summer Bridge Student Project: Monitoring Temperature Increase in Gel Phantom and Tissue during Laser Irradiation Time: Summer 2009 Place: Department of Engineering and Physics, University of Central Oklahoma

27. Long Nguyen, Undergraduate Student University of Central Oklahoma STEP Summer Bridge Student Project: Monitoring Temperature Increase in Gel Phantom and Tissue during Laser Irradiation Time: Summer 2009 Place: Department of Engineering and Physics, University of Central Oklahoma

28. Nikke Sogunno, Undergraduate Student University of Central Oklahoma STEP Summer Bridge Student Project: Monitoring Temperature Increase in Gel Phantom and Tissue during Laser Irradiation Time: Summer 2009 Place: Department of Engineering and Physics, University of Central Oklahoma

29. Toney Stacy, Undergraduate Student University of Central Oklahoma STEP Summer Bridge Student Project: Monitoring Temperature Increase in Gel Phantom and Tissue during Laser Irradiation Time: Summer 2009 Place: Department of Engineering and Physics, University of Central Oklahoma

30. Rachel Evans, Undergraduate Student University of Central Oklahoma STEP Summer Bridge Student Project: Laser Cancer Treatment Using Photothermal Interactions Time: Summer 2010 Place: Department of Engineering and Physics, University of Central Oklahoma

31. Katherine Kastl, Undergraduate Student University of Central Oklahoma STEP Summer Bridge Student Project: Laser Cancer Treatment Using Photothermal Interactions Time: Summer 2010 Place: Department of Engineering and Physics, University of Central Oklahoma

32. Jessnie Jose, Undergraduate Student University of Central Oklahoma STEP Summer Bridge Student Project: Laser Cancer Treatment Using Photothermal Interactions

Wei R. Chen, Ph.D.

Page 32 of 80


33. Jessica Goddard, Undergraduate Student University of Central Oklahoma STEP Summer Bridge Student Project: Laser Cancer Treatment Using Photothermal Interactions Time: Summer 2010 Place: Department of Engineering and Physics, University of Central Oklahoma

34. Mallory Martin, Undergraduate Student University of Central Oklahoma STEP Summer Bridge Student Project: Laser Cancer Treatment Using Photothermal Interactions Time: Summer 2010 Place: Department of Engineering and Physics, University of Central Oklahoma

35. Destiny Brown, Undergraduate Student University of Central Oklahoma STEP Summer Bridge Student Project: Laser Cancer Treatment Using Photothermal Interactions Time: Summer 2010 Place: Department of Engineering and Physics, University of Central Oklahoma

36. Allie Sikes, Undergraduate Student University of Central Oklahoma STEP Summer Bridge Student Project: Laser Cancer Treatment Time: Summer 2012 Place: Department of Engineering and Physics, University of Central Oklahoma

37. Cody Bahavar, Undergraduate Student University of Central Oklahoma STEP Summer Bridge Student Project: Laser Cancer Treatment Time: Summer 2012 Place: Department of Engineering and Physics, University of Central Oklahoma

38. Ellen Boarman, Undergraduate Student University of Central Oklahoma STEP Summer Bridge Student Project: Laser Cancer Treatment Time: Summer 2012 Place: Department of Engineering and Physics, University of Central Oklahoma

39. Keegan Phillips, Undergraduate Student University of Central Oklahoma STEP Summer Bridge Student Project: Laser Cancer Treatment Time: Summer 2012 Place: Department of Engineering and Physics, University of Central Oklahoma

40. Zachary Burton, Undergraduate Student University of Central Oklahoma STEP Summer Bridge Student Project: Laser Cancer Treatment

Wei R. Chen, Ph.D.

Page 33 of 80


41. Aamr Hasanjee, Undergraduate Student University of Central Oklahoma STEP Summer Bridge Student Project: Laser Immunotherapy for Cancer Treatment Time: Summer 2013 Place: Department of Engineering and Physics, University of Central Oklahoma

42. Sheyla Rabei, Undergraduate Student University of Central Oklahoma STEP Summer Bridge Student Project: Laser Immunotherapy for Cancer Treatment Time: Summer 2013 Place: Department of Engineering and Physics, University of Central Oklahoma

43. Weston Schloss, Undergraduate Student University of Central Oklahoma STEP Summer Bridge Student Project: Laser Immunotherapy for Cancer Treatment Time: Summer 2013 Place: Department of Engineering and Physics, University of Central Oklahoma

44. Bailey Vasquez, Undergraduate Student University of Central Oklahoma STEP Summer Bridge Student Project: Laser Immunotherapy for Cancer Treatment Time: Summer 2013 Place: Department of Engineering and Physics, University of Central Oklahoma

45. Ethan Wood, Undergraduate Student University of Central Oklahoma STEP Summer Bridge Student Project: Laser Immunotherapy for Cancer Treatment Time: Summer 2013 Place: Department of Engineering and Physics, University of Central Oklahoma

46. Austin Doughty, Undergraduate Student University of Central Oklahoma STEP Summer Bridge Student Project: Laser Immunotherapy for Cancer Treatment Time: Summer 2014 Place: Department of Engineering and Physics, University of Central Oklahoma

47. Connor West, Undergraduate Student University of Central Oklahoma STEP Summer Bridge Student Project: Laser Immunotherapy for Cancer Treatment Time: Summer 2014 Place: Department of Engineering and Physics, University of Central Oklahoma

48. Chante Preston, Undergraduate Student University of Central Oklahoma STEP Summer Bridge Student Project: Laser Immunotherapy for Cancer Treatment

Wei R. Chen, Ph.D.

Page 34 of 80


49. Marissa Buller, Undergraduate Student University of Central Oklahoma STEP Summer Bridge Student Project: Laser Immunotherapy for Cancer Treatment Time: Summer 2014 Place: Department of Engineering and Physics, University of Central Oklahoma

50. Caleb Mohr, Undergraduate Student University of Central Oklahoma STEP Summer Bridge Student Project: Laser Immunotherapy for Cancer Treatment Time: Summer 2014

Place: Department of Engineering and Physics, University of Central Oklahoma 51. Payden Cloud, Undergraduate Student

University of Central Oklahoma STEP Summer Bridge Student Project: Laser Immunotherapy for Cancer Treatment Time: Summer 2014

Place: Department of Engineering and Physics, University of Central Oklahoma 52. Prayus Barua, Undergraduate Student


Place: Department of Engineering and Physics, University of Central Oklahoma 53. Blake Young, Undergraduate Student


Place: Department of Engineering and Physics, University of Central Oklahoma 54. Brittani Kellogg, Undergraduate Student


Place: Department of Engineering and Physics, University of Central Oklahoma 55. Kegan Silk, Undergraduate Student


Place: Department of Engineering and Physics, University of Central Oklahoma 56. Caleb Shaw, Undergraduate Student

University of Central Oklahoma STEP Summer Bridge Student Project: Laser Immunotherapy for Cancer Treatment

Wei R. Chen, Ph.D.

Page 35 of 80

Time: Summer 2015 Place: Department of Engineering and Physics, University of Central Oklahoma 57. Darian Lincoln, Undergraduate Student


Place: Department of Engineering and Physics, University of Central Oklahoma 58. Alex Pettitt, Undergraduate Student


Place: Department of Engineering and Physics, University of Central Oklahoma

Wei R. Chen, Ph.D.

Page 36 of 80

PUBLICATIONS A. Edited Books / Proceedings 1. Wei R. Chen, Chair/Editor, SPIE Proceedings Volume 6087 “Biophotonics and Immune

Responses”, San Jose, California, January 2006. 2. Wei R. Chen, Chair/Editor, SPIE Proceedings Volume 6438 “Biophotonics and Immune

Responses II”, San Jose, California, January 2007. 3. Wei R. Chen, Chair/Editor, SPIE Proceedings Volume 6857 “Biophotonics and Immune

Responses III”, San Jose, California, January 2008. 4. Wei R. Chen, Chair/Editor, SPIE Proceedings Volume 7178, “Biophotonics and Immune

Responses IV”, San Jose, California, January 2009. 5. Wei R. Chen, Chair/Editor, SPIE Proceedings Volume 7565, “Biophotonics and Immune

Responses V”, San Francisco, California, January 2010. 6. Wei R. Chen, Chair/Editor, SPIE Proceedings Volume 7900, “Biophotonics and Immune

Responses VI”, San Francisco, California, January 2011. 7. Wei R. Chen, Chair/Editor, SPIE Proceedings Volume 8224, “Biophotonics and Immune

Responses VII”, San Francisco, California, January 2012. 8. Wei R. Chen, Chair/Editor, SPIE Proceedings Volume 8582, “Biophotonics and Immune

Responses VIII”, San Francisco, California, February 2013. 9. Wei R. Chen, Chair/Editor, SPIE Proceedings Volume 8944, “Biophotonics and Immune

Responses IX”, San Francisco, California, February 2014. 10. Wei R. Chen, Chair/Editor, SPIE Proceedings Volume 9324, “Biophotonics and Immune

Responses X”, San Francisco, California, February 2015. 11. Wei R. Chen, Chair/Editor, SPIE Proceedings Volume 9709, “Biophotonics and Immune

Responses XI”, San Francisco, California, February 2016.

B. Book Chapters 1. Zheng Huang, Hong Liu, and Wei R. Chen, “Mechanisms and Applications of Photodynamic

Therapy”, in Fundamentals and Applications of Biophotonics in Dentistry, Editors Anil Kishen and Anand Asundi, (Imperial College Press, 2007), pp 154-181.

2. Wei R. Chen, Xiaosong Li, Mark F. Naylor, Hong Liu, and Robert E. Nordquist, “Advances in Cancer Photothermal Therapy”, in Handbook of Photonics for Biomedical Science, Editors Valery V. Tuchin, (CRC Press, 2010), pp 499-526.

3. Tomas Hode, Xiaosong Li, Mark Naylor, Lars Hode, Peter Jenkins, Gabriela Ferrel, Robert E. Nordquist, Orn Adalsteinsson, John Lunn, Michael R. Hamblin, Luciano Alleruzzo, Wei R. Chen, "Laser Immunotherapy", in Handbook of Photomedicine, Editors Michael R. Hamblin and Ying-Ying Huang, (Taylor & Francis, 2013), ISBN 978-1-4398-8469-0, pp 763-770.

4. Mark F. Naylor, Xiaosong Li, Robert E. Nordquist, Tomas Hode, Orn Adalsteinsson, Hong Liu, and Wei R. Chen, “In Situ Immunotherapy for Melanoma”, in From Early Detection to Treatment / Book 2, ISBN 980-953-307-600-8, to be published.

C. Refereed Journal Papers 1 Wei R. Chen and Rudolph C. Hwa, "Geometrical scaling, branching and Koba-Nielson-Olesen

scaling", Physical Review D: Particles and fields, 36, 760-764, 1987.

Wei R. Chen, Ph.D.

Page 37 of 80

2 Wei R. Chen, Rudolph C. Hwa and Xing-Nian Wang, "Particle productivity in pp and pA collisions", Physical Review D: Particles and fields, 38, 3394-3396, 1988.

3 Wei R. Chen and Rudolph C. Hwa, "Geometrical Branching model: Phenomenology with jets", Physical Review D: Particles and fields, 39, 179-186, 1989.

4 Wei R. Chen, Rudolph C. Hwa and Xin-Nian Wang, "Cluster cascading in the geometrical branching model", Physical Review D: Particles and fields, 43, 2425-2428, 1991.

5 Moustafa Bahran, Wei R. Chen and George R. Kalbfleisch, "Fermi theory of nuclear decay and heavy neutrino searches", Physical Review D: Particles and fields, 47, (Rapid Communications) R759-R763, 1993.

6 Wei R. Chen, Robert L. Adams, Sean Heaton, D. Thomas Dickey, Kenneth E. Bartels and Robert E. Nordquist, "Chromophore-enhanced laser-tumor tissue photothermal interaction using 808 nm diode laser", Cancer Letters, 88, 15-19, 1995.

7 Wei R. Chen, Robert L. Adams, Kenneth E. Bartels and Robert E. Nordquist, “Chromophore-enhanced in vivo tumor cell destruction using an 808-nm diode laser”, Cancer Letters, 94, 125-131, 1995.

8 Wei R. Chen, Arne Troelstra, and Xifan Liu, “Acceleration of a pendulum with arbitrary releasing positions”, NCSSSMST Journal, 2, 17-22, 1995.

9 Wei R. Chen, Robert L. Adams, Aaron K. Higgins, Kenneth E. Bartels and Robert E. Nordquist, “Photothermal effects on murine mammary tumors using indocyanine green and an 808-nm diode laser: An in vivo efficacy study”, Cancer Letters, 98, 169-173, 1996.

10 Wei R. Chen, Robert L. Adams, Raoul Carubelli and Robert E. Nordquist, “Laser-photosensitizer assisted immunotherapy: A novel modality in cancer treatment”, Cancer Letters, 115, 25-30, 1997.

11 Li-hong Wang, Robert E. Nordquist and Wei R. Chen, “Optimal beam size for light delivery to absorption-enhanced tumors buried in biological tissues and effect of multiple beam delivery: a Monte Carlo study”, Applied Optics Vol. 36, 8286-8291, 1997.

12 Wei R. Chen and Arne A. Troelstra, “The kinetic energy of a rotating figure skater”, NCSSSMST Journal, Vol. 3(2), 3-5, 1998.

13 Joy Lin, Arne A. Troelstra and Wei R. Chen, “Quantization of a two-body system with a 1/r4 attractive force: A hypothetical quantum atomic structure”, NCSSSMST Journal, Vol. 4(1), 9-12, 1998.

14 Wei R. Chen, Wei-Guo Zhu, Joseph R. Dynlacht, Hong Liu and Robert E. Nordquist, “Long-term tumor resistance induced by laser photo-immunotherapy”, International Journal of Cancer, 81, 808-812, 1999.

15 Fang Xu, Hong Liu, Xizeng Wu, Hangyi Jiang, Robert E. Nordquist and Wei R. Chen, “Measurement of x-ray attenuation coefficients of aqueous solutions of indocyanine green and glycated chitosan”, Medical Physics, 26, 1371-1374, 1999.

16 Wei R. Chen, Hong Liu, John A. Nordquist and Robert E. Nordquist, “Tumor cell damage and leukocyte infiltration after laser immunotherapy treatment”, Lasers in Medical Science, 15, 43-48, 2000.

17 Hong Liu, Hangyi Jiang, Laurie L. Fajardo, Andrew Karellas, and Wei R. Chen, “Lens distortion in optically coupled digital x-ray imaging”, Medical Physics, 27, 906-912, 2000.

18 Hangyi Jiang, Hong Liu, Ge Wang, Wei Chen and Laurie L. Fajardo, “A localization algorithm and error analysis for stereo x-ray image guidance”, Medical Physics, 27, 885-893, 2000.

19 Wei R. Chen, Anil K. Singhal, Hong Liu, and Robert E. Nordquist, “Laser immunotherapy induced antitumor immunity and its adoptive transfer”, (Advances in Brief) Cancer Research, 61, 459-461, 2001.

Wei R. Chen, Ph.D.

Page 38 of 80

20 Hong Liu, Hangyi Jiang, Laurie L. Fajardo, Andrew Karellas, and Wei R. Chen, “Characteristics of lens distortion and methods to correct geometrical distortion caused by lenses in optically coupled digital x-ray imaging: A response to Dr. E. H. B. M. Gronenschild's comment”, Medical Physics, Vol. 28(6), 1139-1140, 2001.

21 Wei R. Chen, Hong Liu and Robert E. Nordquist, “Dynamically observing intratumor injection of laser-absorbing dye and immunoadjuvant using digital x-ray imaging technique”, Optical Engineering, Vol. 40 (7), 1249-1254, 2001.

22 Hangyi Jiang, Hong Liu, and Wei R. Chen, “Determination of the monoplane 3D system geometry in X-ray imaging guidance”, Journal of X-Ray Science and Technology, 9, 19-28, 2001.

23 Hangyi Jiang, Wei R. Chen, Ge Wang, and Hong Liu, “Localization error analysis for stereo x-ray image guidance with probability method”, Medical Engineering and Physics, Vol. 23, 573-581, 2001.

24 Hangyi Jiang, Wei R. Chen, and Hong Liu, “Position-dependent image characteristics of a CCD-based full-field digital mammography system”, Journal of X-Ray Science and Technology, 9, 101-111, 2001.

25 Fabrice Ouandji, Eric Potter, Wei R. Chen, Yuhua Li, David Tang, and Hong Liu, “Characterization of a CCD-based digital x-ray imaging system for small animal studies: Properties of spatial resolution”, Applied Optics, Vol. 41, No.13, 2420-2427, 2002.

26 Yuhua Li, Wei R. Chen, Yimou Zhang, Wei Qian, and Hong Liu, “Comparison of analog and digital Fourier Transforms in medical image analysis”, Journal of Biomedical Optics, Vol. 7, No. 2 255-261, 2002.

27 Wei R. Chen, Jerry W. Ritchey, Kenneth E. Bartels, Hong Liu, and Robert E. Nordquist, “Effect of different components of laser immunotherapy in treatment of metastatic tumors in rats”, Cancer Research, 62 4295-4299, 2002.

28 Vinson G. Liu, Thomas M. Cowan, Sang-Won Jeong, Steven L. Jacques, Evan C. Lemley and Wei R. Chen, “Selective photothermal interaction using an 805-nm diode laser and indocyanine green in gel phantom and chicken breast tissue”, Lasers in Medical Science, Vol. 17 No. 4, 272-279, 2002.

29 Wei R. Chen, Hong Liu, Raoul Carubelli and Robert E. Nordquist, “Synergistic Effect of Photothermal and Photoimmunological Reactions in Treatment of Metastatic Tumors”, Journal of X-Ray Science and Technology, 10, 225-235, 2002.

30 Michael D. Lucroy, Wei R. Chen, Tisha D. Ridgway, Russell G. Higbee, and Kenneth E. Bartels, “Selective laser-induced hyperthermia for the treatment of spontaneous tumors in dogs”, Journal of X-Ray Science and Technology, 10, 237-243, 2002.

31 Hangyi Jiang, Wei R. Chen, and Hong Liu, “Techniques to improve the accuracy and to reduce the variance in noise power spectrum measurement”, IEEE Transactions on Biomedical Engineering, 49, 1270-1278, 2002.

32 D. Richard Ishmael, Wei R. Chen, John Nordquist, Hong Liu, and Robert E. Nordquist, “Synergistic Effect of Sequential Administration of Mitoguazone (MGBG) and Gemcitabine in Treating Tissue Cultured Human Breast Cancer Cells and Mammary Rat Tumors”, Cancer Investigation, 21, 217-226, 2003.

33 D. Richard Ishmael, Wei R. Chen, Steven A. Hamilton, Hong Liu, and Robert E. Nordquist, “A Phase I Human Trial of Mitoguazone and Gemcitabine Sequential Bi-Weekly Treatment of Cancer Patients”, Cancer Investigation, 21, 542-549, 2003.

34 Wei R. Chen, Raoul Carubelli, Hong Liu, and Robert E. Nordquist, “Laser Immunotherapy: A Novel Treatment Modality for Metastatic Tumors”, Molecular Biotechnology, 25, 37-43, 2003.

Wei R. Chen, Ph.D.

Page 39 of 80

35 Wei R. Chen, Raoul Carubelli, Hong Liu, and Robert E. Nordquist, “Detection of Anti-Tumor Immunity Induced by Laser Immunotherapy”, Molecular Biotechnology, 25, 45-51, 2003.

36 Wei R. Chen, Sang Won Jeong, Michael D. Lucroy, Roman F. Wolf, Eric W. Howard, Hong Liu, and Robert E. Nordquist, “Induced antitumor immunity against DMBA-4 metastatic mammary tumors in rats using laser immunotherapy”, International Journal of Cancer, 107 (6), 1053-1057, 2003.

37 Christopher A. Bailey, Thomas M. Cowan, Vinson G. Liu, Evan C. Lemley, and Wei R. Chen, “Optimization of Selective Hyperthermia”, Journal of Biomedical Optics, 9 (3), 648-654, 2004.

38 Chang Ye, Qingming Luo, Wei R. Chen, Wenxi Liang, Weihua Luo, and Aijun Zhong, “Limitation in Detecting Internal Blood Vessels Using Digital X-ray Imaging Technique”, Journal of X-Ray Science and Technology, 12, 59-71, 2004.

39 Hemanth Athiraman, Roman F. Wolf, Kenneth E. Bartels, Suman Shivakoti, Hong Liu, and Wei R. Chen, “Selective Photothermal Tissue Interaction Using 805-nm Laser and Indocyanine Green in Tissue welding”, Journal of X-Ray Science and Technology, 12, 117-126, 2004.

40 Wei R. Chen, Mladen Korbelik, Kenneth E. Bartels, Hong Liu, Jinghai Sun, and Robert E. Nordquist, “Enhancement of laser cancer treatment by a chitosan-derived immunoadjuvant”, Photochemistry and Photobiology, 81, 190-195, 2005.

41 David Tang, Yuhua Li, Jessica Wong, Sunny Po, Eugene Patterson, Wei R. Chen, Warren Jackman, and Hong Liu, “Characteristics of a CCD-based Optical Mapping System for the Study of Cardiac Arrhythmias”, Journal of Biomedical Optics, 10, 024009-1-024009-7, 2005.

42 Qirong Zhang, Yuhua Li, Ben Steele, Xizeng Wu, Wei R. Chen, John Rong, and Hong Liu, “Comparison of a CMOS-based and a CCD-based digital x-ray imaging system: Observer studies”, Journal of Electronic Imaging, 14(2), 023002-1-023002-6, 2005.

43 Xingwei Wang, Bin Zheng, Marc Wood, Shibo Li, Wei R. Chen, and Hong Liu, “Development and evaluation of automated systems for detection and classification of banded chromosomes: current status and future perspectives”, Journal of Physics D: Applied Physics, 38, 2536–2542, 2005.

44 D. Richard Ishmael, Hong Liu, John A. Nordquist, Robert E. Nordquist, and Wei R. Chen, “Phase I Trial of Concurrent Administration of Topotecan and Docetaxel for Cancer Treatment”, Journal of Applied Research, 5, 53-60, 2005.

45 Yueqing Gu, Wei R. Chen, Mengna Xia, Sang Won Jeong and Hanli Liu, “Effects of Photothermal Therapy on Breast Tumor Vascular Contents: Noninvasive Monitoring by Near-Infrared Spectroscopy”, Photochemistry and Photobiology, 81, 1002-1009, 2005.

46 Wei R. Chen, Zheng Huang, Mladen Korbelik, Robert E. Nordquist, and Hong Liu, “Photoimmunotherapy for Cancer Treatment”, Journal of Environmental Pathology, Toxicology and Oncology, 25, 281-291, 2006.

47 Qirong Zhang, John Rong, Xizeng Wu, Yuhua Li, Wei R. Chen, and Hong Liu, “Impacts of Filtration on Contrast-Detail Detectability of an X-ray Imaging System”, International Journal of Biomedical Imaging, Vol 2006, 95754, 1-8, 2006.

48 Zheng Huang, Qian Yong Gang and Wei R. Chen “Photodynamic Therapy and Anti-tumor Immune Responses”, Chinese Journal of Laser Medicine and Surgery, 15 (2), 121-124, 2006 (in Chinese).

49 Yunxia Wu, Da Xing, and Wei R. Chen, “Single cell FRET imaging for determination of pathway of tumor cell apoptosis induced by photofrin-PDT”, Cell Cycle, 5:7, 720-734, 2006.

50 Da Zhang John Rong, Robert Chu, Wei R. Chen, and Hong Liu, “DQE Measurements in Magnification X-ray Imaging”, Journal of X-Ray Science and Technology, 14, 141-150, 2006.

Wei R. Chen, Ph.D.

Page 40 of 80

51 Jared J. Crochet, Surya C Gnyawali, Yichao Chen, Evan C. Lemley, Lihong V. Wang and Wei R. Chen, “Temperature Distribution in Selective Laser-Tissue Interaction”, Journal of Biomedical Optics, Vol. 11, 034031, 1-10, 2006.

52 Wei R. Chen and Zheng Huang, “Biophotonics and Immune Responses – Highlights from a new SPIE Photonics West Conference (BIOS 2006)”, Photodiagnosis and Photodynamic Therapy, Vol. 3, 184-189, 2006.

53 Wei R. Chen, Kenneth E. Bartels, Hong Liu, and Robert E. Nordquist, “Laser-Photothermal Effect on Skin Tissue – Damage and Recovery”, Journal of X-Ray Science and Technology, 14, 207-215, 2006.

54 Mark F. Naylor, Wei R. Chen, T. Kent Teague, Lisa Perry, and Robert E. Nordquist, “In Situ Photo Immunotherapy: A Tumor-Directed Treatment Modality for Melanoma”, British Journal of Dermatology, 155, 1287-1292, 2006.

55 Xingwei Wang, Shibo Li, Hong Liu, John J. Mulvihill, Wei R. Chen, and Bin Zheng, “A Computer-Aided Method to Expedite the Evaluation of Prognosis for Childhood Acute Lymphoblastic Leukemia”, Technology in Cancer Research and Treatment 5(4), 429-436, 2006.

56 Da Zhang, John Rong, Wei R. Chen, Xizhen Wu and Hong Liu, “Impact of Additive Noise on System Performance of a Digital X-ray Imaging System”, IEEE Transactions on Biomedical Engineering, 54, 69-73, 2007.

57 Yinyuan Wu, Da Xing, Lei Liu, Tongsheng Chen, and Wei R. Chen, “Fluorescence Resonance Energy Transfer Analysis of Bid Activation in Living Cells during Ultraviolet-induced Apoptosis”, Acta Biochimica et Biophysica Sinica, 39 (1), 37–45, 2007.

58 Feng Wu, Lan Zhou, and Wei R. Chen, “Host antitumour immune responses to HIFU ablation”, International Journal of Hyperthermia, 23(2): 165–171, 2007.

59 Liangzhong Xiang, Da Xing, Huaimin Gu, Diwu Yang, Sihua Yang, Lvming Zeng, and Wei R. Chen, “Real-time optoacoustic monitoring of vascular damage during photodynamic therapy treatment of tumor”, Journal of Biomedical Optics, Vol 12, 014001 (Feb) 2007.

60 Feng Wu, Gail ter Haar, and Wei R. Chen, “High-intensity focused ultrasound ablation of breast cancer”, Expert Review of Anticancer Therapy, Vol 7, No. 6, 823-831, 2007.

61 Tongsheng Chen, Jinjun Wang, Da Xing, and Wei R. Chen, “Spatio-Temporal Dynamic Analysis of Bid Activation and Apoptosis Induced by Alkaline Condition in Human Lung Adenocarcinoma Cell”, Cellular Physiology and Biochemistry, Vol. 20, 569-578, (DOI:10.1159/000107540), 2007.

62 Shengnan Wu, Da Xing, Fang Wang, Tongsheng Chen, and Wei R. Chen, “Mechanistic Study of Apoptosis Induced by High Fluence Low Power Laser Irradiation Using Fluorescence Imaging Techniques”, Journal of Biomedical Optics, Vol. 12, 064015 (1-10), 2007.

63 Sihua Yang, Da Xing, Yeqi Lao, Diwu Yang, Lvming Zeng, Liangzhong Xiang, and Wei R. Chen, “Noninvasive monitoring of traumatic brain injury and post-traumatic rehabilitation with laser-induced photoacoustic imaging”, Applied Physics Letters, 90, 243902 (1-3), 2007.

64 Yinyuan Wu, Da Xing, Wei R. Chen, and Xichao Wang, “Bid is not required for Bax translocation during UV-induced apoptosis”, Cellular Signalling, Vol. 19 (12) 2468-2478, 2007.

65 Surya C. Gnyawali, Yichao Chen, Feng Wu, Kenneth E. Bartels, James P. Wicksted, Hong Liu, and Wei R. Chen, “Temperature Measurement on Tissue Surface during Laser Irradiation”, Medical and Biological Engineering and Computing, Vol. 46, 159-168, 2008.

66 Xingwei Wang, Shibo Li, Hong Liu, Marc Wood, Wei R. Chen, and Bin Zheng, “Automated identification of analyzable metaphase chromosomes depicted on microscopic digital images“, Journal of Biomedical Informatics, 41, 264-271, 2008.

Wei R. Chen, Ph.D.

Page 41 of 80

67 Lei Liu, Da Xing, Wei R. Chen, Tongsheng Chen, Yihui Pei, and Xuejuan Gao,“Calpain-mediated pathway dominates cisplatin-induced apoptosis in human lung adenocarcinoma cells as determined by real-time single cell analysis”, International Journal of Cancer, 122, 2210-2222, 2008.

68 Abby Deans, Linda Hess, Michael Koss, Hong Liu, and Wei R. Chen, “Laser Photothermal Effects on Tumor Vasculature Using Laser Doppler Flowmetry”, Journal of X-Ray Science and Technology, 16, 51-57, 2008.

69 Feifan Zhou, Da Xing, and Wei R. Chen, “Dynamics and mechanism of HSP70 translocation induced by photodynamic therapy treatment”, Cancer Letters, 264, 135-144, 2008.

70 Debin Zhu, Yabing Tang, Da Xing, and Wei R. Chen, “PCR-free quantitative detection of genetically modified organism from raw materials. An electrochemiluminescence-based bio bar code method”, Analytical Chemistry, 80, 3566-3571, 2008.

71 Yichao Chen, Surya C. Gnyawali, Feng Wu, Hong Liu, Yasvir A. Tesiram, Andrew Abbott, Rheal A. Towner, and Wei R. Chen, “Magnetic resonance imaging guidance for laser photothermal therapy”, Journal of Biomedical Optics, Vol. 13, 044033, 2008.

72 Xingwei Wang, Bin Zheng, Shibo Li, Roy Zhang, John J. Mulvihill, Wei R.Chen, and Hong Liu, “Automated detection and analysis of fluorescent in situ hybridization spots depicted in digital microscopic images of pap-smear specimens”, Journal of Biomedical Optics, 14, 021002, 2009.

73 Feifan Zhou, Da Xing, Zhongmin Ou, Baoyan Wu, Daniel E. Resasco, and Wei R. Chen, “Cancer photothermal therapy in the near-infrared region by using single-walled carbon nanotubes”, Journal of Biomedical Optics, 14, 021009, 2009.

74 Lifang Liang, Xichao Wang, Da Xing, Tongsheng Chen, and Wei R. Chen, “Noninvasive Determination of Cell Nucleoplasmic Viscosity by Fluorescence Correlation Spectroscopy”, Journal of Biomedical Optics, 14, 024013, 2009.

75 Shengnan Wu, Da Xing, Xuejuan Gao, and Wei R. Chen, “High fluence low-power laser irradiation induces mitochondrial permeability transition mediated by reactive oxygen species”, Journal of Cellular Physiology, 218(3), 603-611, March 2009.

76 Sheng Song, Feifan Zhou, Robert E. Nordquist, Raoul Carubelli, Hong Liu, and Wei R. Chen, “Glycated chitosan as a new non-toxic immunological stimulant”, Immunopharmacology and Immunotoxicology, 31(2), 202–208, 2009.

77 Feifan Zhou, Da Xing, and Wei R. Chen, “Single Cell Imaging of Bax Translocation during Apoptosis Induced by Photofrin-PDT”, Journal of Innovative Optical Health Sciences, 2, 209-214, 2009.

78 Feifan Zhou, Da Xing, and Wei R. Chen, “Regulation of HSP70 on activating macrophages using PDT-induced apoptotic cells”, International Journal of Cancer, 125, 1380-1389, 2009.

79 Xianwang Wang, Da Xing, Lei Liu, and Wei R. Chen, “BimL directly neutralizes Bcl-xL to promote Bax activation during UV-induced apoptosis”, FEBS Letters 583 (12), 1873-1879, 2009.

80 Lei Liu, Da Xing, and Wei R. Chen, "Micro-calpain regulates caspase-dependent and apoptosis inducing factor-mediated caspase-independent apoptotic pathways in cisplatin-induced apoptosis”, International Journal of Cancer, 125 (12), 2757-2766, 2009.

81 Xiaoming Zhou, Da Xing, Yonghong Tang, and Wei R. Chen, “PCR-Free Detection of Genetically Modified Organisms Using Magnetic Capture Technology and Fluorescence Cross-Correlation Spectroscopy”, PLoS ONE, 4(11): e8074. doi:10.1371/journal.pone.0008074, 2009.

Wei R. Chen, Ph.D.

Page 42 of 80

82 Feifan Zhou, Da Xing, Shengnan Wu, and Wei R. Chen, “Intravital imaging of tumor apoptosis with FRET probes during tumor therapy”, Molecular Imaging and Biology, 12, 63-70, 2010.

83 Feifan Zhou, Da Xing, Baoyan Wu, Shengnan Wu, Zhongmin Ou, and Wei R. Chen, “New insights of transmembranal mechanism and subcellular localization of noncovalently modified single-walled carbon nanotubes”, Nano Letters, 10, 1677-1681, 2010.

84 Yunlong Li, Da Xing, Qun Chen, and Wei R. Chen, “Enhancement of Chemotherapeutic Agent-Induced Apoptosis by Inhibition of NF-κB Using Ursolic Acid”, International Journal of Cancer, 127, 462-473, 2010.

85 Xiaosong Li, Tomas Hode, Maria C. Guerra, Gabriela L. Ferrel, John A. Lunn, Orn Adalsteinsson, Robert E. Nordquist, and Wei R. Chen, “Combined effects of selective photothermal therapy and immunoadjuvant against Stage IV breast cancer”, Journal of Innovative Optical Health Science, 3, 279-284, 2010.

86 Hui Li, Lei Liu, Da Xing, and Wei R. Chen, “Inhibition of JNK/Bim Pathway by Hsp70 Prevents Bax Activation in UV-induced Apoptosis”, FEBS Letters, 84(22), 4672-4678, 2010.

87 Xiaosong Li, Mark F. Naylor, Henry Le, Robert E. Nordquist, T. Kent Teague, C. Anthony Howard, Cynthia Murray, and Wei R. Chen, “Clinical effects of in situ photoimmunotherapy on late-stage melanoma patients: A preliminary study”, Cancer Biology and Therapy, 10(11), 1081-1087, 2010.

88 Xiaosong Li and Wei R. Chen, “Laser Immunotherapy: Novel Modality to Treat Cancer through Specific Antitumor Immune Response”, Chinese Journal of Lasers, 37(11), 2698-2702, 2010.

89 Xiaosong Li, Henry Le, Roman F. Wolf, Vivian A. Chen, Akhee Sarkar, Robert E. Nordquist, Halie Ferguson, Hong Liu, and Wei R. Chen, “Long-Term Effect on EMT6 Tumors in Mice Induced by Combination of Laser Immunotherapy and Surgery”, Integrative Cancer Therapies, 10, 368-373, 2011.

90 Xiaosong Li, Gabriela L. Ferrel, Maria C. Guerra, Tomas Hode, John A. Lunn, Orn Adalsteinsson, Robert E. Nordquist, Hong Liu, and Wei R. Chen, “Preliminary safety and efficacy results of laser immunotherapy for the treatment of metastatic breast cancer patients”, Photochemical & Photobiological Sciences, 10, 817-821, 2011.

91 Xiaohui Zheng, Da Xing, Feifan Zhou, Baoyan Wu, and Wei R. Chen, “Indocyanine Green-Containing Nanostructure as Near Infrared Dual-Functional Targeting Probes for Optical Imaging and Photothermal Therapy”, Molecular Pharmaceutics, 8, 447-456, 2011.

92 Feifan Zhou, Sheng Song, Wei R. Chen, and Da Xing, “Immunostimulatory properties of glycated chitosan”, Journal of X-Ray Science and Technology, 19, 285–292, 2011.

93 Feifan Zhou, Shengnan Wu, Baoyan Wu, Wei R. Chen, and Da Xing, “Mitochondria-Targeting Single-Walled Carbon Nanotubes for Cancer Photothermal Therapy”, Small, 7 (19), 2727–2735, 2011.

94 Kelvin Le, Xiaosong Li, Daniel Figueroa, Rheal A. Towner, Philippe Garteiser, Debra Saunders, Nataliya Smith, Hong Liu, Tomas Hode, Robert E. Nordquist, and Wei R. Chen, “Assessment of Thermal Effects of Interstitial Laser Phototherapy on Mammary Tumors Using Proton Resonance Frequency Method”, Journal of Biomedical Optics, 16(12), 128001, 2011.

95 Feifan Zhou, Shengnan Wu, Sheng Song, Wei R. Chen, Daniel E. Resasco, and Da Xing, “Antitumor Immunologically Modified Carbon Nanotubes for Photothermal Therapy”, Biomaterials, 33(11), 3235-42, 2012.

96 Xianwang Wang, Wei R. Chen, and Da Xing, “A pathway from JNK through decreased ERK and Akt activities for FOXO3a nuclear translocation in response to UV irradiation”, Journal of Cellular Physiology, 227(3), 1168-1178, 2012.

Wei R. Chen, Ph.D.

Page 43 of 80

97 Xiaohui Zheng, Feifan Zhou, Baoyan Wu, Wei R. Chen, and Da Xing, “Enhanced tumor treatment using biofunctional indocyanine green-containing nanostructure by intratumoral or intravenous injection”, Molecular Pharmaceutics, 9(3), 514-22, 2012.

98 Feifan Zhou, Shengnan Wu, Yi Yuan, Wei R. Chen, and Da Xing, “ Mitochondria-Targeting Photoacoustic Therapy Using Single-Walled Carbon Nanotubes”, Small, 8(10), 1543-1550. 2012.

99 Zheng Li, Shibo Li, Zheng Bin, Roy Zhang, Yuhua Li, Huimin Tian, Wei R. Chen, Hong Liu, “Potential clinical impact of three-dimensional visualization for fluorescent in situ hybridization image analysis”, Journal of Biomedical Optics 17, JBO Letters, 050501-(1-3), 2012.

100 Zhifang Li, Hui Li, Zhiping Zeng, Wengming Xie, and Wei R. Chen, “Determination of an absolute optical absorption coefficient with a focusing photoacoustic imaging”, Journal of Biomedical Optics, 17, 061216(1-6), 2012.

101 Xiaosong Li, Min Min, Ying Gu, Nan Du, Tomas Hode, Robert E. Nordquist, Roman F. Wolf, Eric Howard, John A. Lunn, Orn Adalsteinsson, and Wei R. Chen, “Laser Immunotherapy: Concept, Possible Mechanism, Clinical Applications and Recent Experimental Results”, IEEE Journal of Selected Topics in Quantum Electronics, 18, 1434-1438, 2012.

102 Sheng Song, Feifan Zhou, and Wei R. Chen, “Low-level laser therapy regulates microglial function through Src-mediated signaling pathways: Implications for neurodegenerative diseases”, Journal of Neuroinflammation, 9, 219(1-17), 2012.

103 Yuchen Qiu, Xiaodong Chen, Yuhua Li, Bin Zheng, Shibo Li, Wei R. Chen, and Hong Liu, “The impact of the optical depth of field on cytogenetic image quality”, Journal of Biomedical Optics, 17(9), 096017(1-7), 2012.

104 Sheng Song, Feifan Zhou, Wei R. Chen, and Da Xing, “PDT-induced HSP70 externalization up-regulates NO production via TLR2 signal pathway in macrophages”, FEBS Letters, 587, 128-135, 2013.

105 Jie Cao, Sisi Cui, Siwen Li, Changli Du, Junmei Tian, Shunan Wan, Zhiyu Qian, Yueqing Gu, Wei R. Chen, and Guangji Wang, “Targeted cancer therapy with a 2-deoxyglucose-based adriamycin complex”, Cancer Research, 73(4), 1362-1373, 2013.

106 Xiaosong Li, Min Min, Nan Du, Ying Gu, Tomas Hode, Mark Naylor, Dianjun Chen, Robert E. Nordquist, and Wei R. Chen, “Chitins, chitosans, and glycated chitosan regulate immune responses: the novel adjuvants for cancer vaccine”, Clinical and Developmental Immunology, 2013:387023, 2013.

107 Zhifang Li, Hui Li, Hui Zhang, Xiaona Lin, and Wei R. Chen, “Extracting optical scattering properties based on phase contrast images for diagnosing stomach cancer”, Laser Physics, 23(4), 045605, 2013.

108 John F. Barthell, Wei R. Chen, Beverly K. Endicott, Charles A. Hughes, William J. Radke, Charlotte K. Simmons, and Gregory M. Wilson, “Encouraging and Sustaining a Culture of Student-Centered Research at a Predominantly Undergraduate Institution”, CUR Quarterly, 34(1), 41-47, 2013.

109 Daqing Piao, Rheal A. Towner, Nataliya Smith, and Wei R. Chen, “Magnetothermoacoustics from magnetic nanoparticles by short bursting or frequency chirped alternating magnetic field: A theoretical feasibility analysis”, Medical Physics, 40, 063301, 2013.

110 Feifan Zhou, Xiaosong Li, Sheng Song, Joseph T. Acquaviva III, Roman F. Wolf, Eric W. Howard, and Wei R. Chen, "Anti-tumor responses induced by laser irradiation and immunological stimulation using a mouse mammary tumor model", Journal of Innovative Optical Health Sciences, 6(4), 1350039, 2013.

Wei R. Chen, Ph.D.

Page 44 of 80

111 Yuchen Qiu, Xiaodong Chen, Yuhua Li, Wei R. Chen, Bin Zheng, Shibo Li, Hong Liu, "Evaluations of auto-focusing methods under a microscopic imaging modality for the metaphase chromosome image analysis", Analytical Cellular Pathology, 36, 37–44, 2013.

112 Sheng Song, Wei R. Chen, and Feifan Zhou, "Effects of LPLI on microglial phagocytosis in LPS-induced neuroinflammation model", Journal of Innovative Optical Health Sciences, 7(3) 1350049(1-10), 2014.

113 Shengnan Wu, Feifan Zhou, Yanchun Wei, Wei R. Chen, Qun Chen, and Da Xing, “Cancer Phototherapy via Selective Photoinactivation of Respiratory Chain Oxidase to Trigger a Fatal Superoxide Anion Burst”, Antioxidants & Redox Signaling, 20(5), 733-746, 2014.

114 Ying-Ling Chen, Chung-Yih Wang, Feng-Yi Yang, Bo-Sheng Wang, Jason Y. Chen Liang-Ting Lin, Jyh-Der Leu, Fu-Du Chen, Yi-Jang Lee, and Wei R. Chen, "Synergistic effects of the immunoadjuvant glycated chitosan with high-intensity focused ultrasound on suppression of metastases in a syngeneic breast tumor model", Cell Death and Diseases, 5, e1178, 2014.

115 Siwen Li, Jingyi Qin, Caiping Tian, Jie Cao, Guissi Fida, Zhaohui Wang, Haiyan Chen, Zhiyu Qian, Wei R. Chen, and Yueqing Gu, "The targeting mechanism of DHA ligand and its enhancement for tumor therapy", Oncotarget, 5(11), 3622-3635, 2014.

116 Shu-lian Wu, Hui Li, Xiao-man Zhang, Wei R. Chen, and Yunxia Wang “Character of skin on photo-thermal response and its regeneration process using second-harmonic generation microscopy”, Lasers in Medical Science, 29, 141-146, 2014.

117 Zhifang Li, Haiyu Chen, Hui Li, and Wei R. Chen, "Optical properties of tissues quantified using morphological granulometry from phase-contrast images of thin tissue samples", Journal of X-Ray Science and Technology, 23, 111–118, 2015.

118 Feifan Zhou, Xiaosong Li, Mark F. Naylor, Tomas Hode, Robert E. Nordquist, Luciano Alleruzzo, Joseph Raker, Samuel S.K. Lam, Nan Du, Lei Shi, Xiuli Wang, Wei R. Chen, "InCVAX–A novel strategy for treatment of late-stage, metastatic cancers through photoimmunotherapy induced tumor-specific immunity", Cancer Letters, 359, 169-177, 2015, doi:10.1016/j.canlet.2015.01.029.

119 Zhifang Li, Haiyu Chen, Feifan Zhou, Hui Li, and Wei R. Chen, "Interstitial photoacoustic sensor for measurement of tissue temperature during interstitial laser phototherapy", Sensors, 15, 5583-5593, 2015; doi:10.3390/s150305583.

120 Jie Ji, Zhixia Fan, Feifan Zhou, Xiaojie Wang, Lei Shi, Haiyan Zhang, Peiru Wang, Degang Yang, Linglin Zhang, Wei R. Chen, and Xiuli Wang, “Improvement of DC vaccine with ALA-PDT induced immunogenic apoptotic cells for skin squamous cell carcinoma”, Oncotarget, 6(10), 17135-17146, 2015.

121 Joseph T. Acquaviva III, Cody F. Bahavar, Feifan Zhou, Xiaosong Li, Eric W. Howard, Liz C. Bullen, Ricardo P. Silvy, and Wei R. Chen, “Anti-Tumor Response Induced by Immunologically Modified Carbon Nanotubes and Laser Irradiation Using Rat Mammary Tumor Model”, Journal of Innovative Optical Health Science, 8(4), 1550036 (1-8), 2015.

122 Samuel S.K. Lam, Feifan Zhou, Tomas Hode, Robert E. Nordquist, Luciano Alleruzzo, Joseph Raker, and Wei R. Chen, "Advances in strategies and methodologies in cancer immunotherapy", Discovery Medicine, 105, 293-301, 2015.

123 Xiaojie Wang, Jie Ji, Haiyan Zhang, Zhixia Fan, Linglin Zhang, Lei Shi, Feifan Zhou, Wei R. Chen, Hongwei Wang, and Xiuli Wang, “Simulation of dendritic cells by DAMPs in ALA-PDT treated SCC tumor cells”, Oncotarget, . doi: 10.18632, 2015.

124 Feifan Zhou, Robert E. Nordquist, and Wei R. Chen, “Photonics immunotherapy – A novel strategy for cancer treatment”, Journal of Innovative Optical Health Science, 2016 (in press).

Wei R. Chen, Ph.D.

Page 45 of 80

125 Jie Ji, Yunfeng Zhang, Wei R. Chen, and Xuili Wang, “DC Vaccine Generated By ALA-PDA-Induced Immunogenic Apoptotic Cells for Skin Squamous Cell Carcinoma”, Oncoimmunology, 2016 (in press).

126 Mark F. Naylor, Feifan Zhou, Brian V. Geister, Robert E. Nordquist, and Wei R. Chen, “Melanoma Treated with Laser Immunotherapy and T Cell Stimulations”, JAMA Dermatology, 2016 (in press).

D. Proceeding Papers 1. Wei R. Chen and Rudolph C. Hwa, "Cross sections and multiplicity distributions with

minijets", in Proc. of Shandong Workshop on Multiparticle Production, Jinan, China, 1987, edited by R. C. Hwa and Q.-B. Xie (World Scientific, Singapore, 1988), 276-282.

2. Wei R. Chen, "Massive cluster decay in multiparticle production", Conference of Particle and Fields, Bulletin of the American Physical Society, Jan. 1990.

3. Wei R. Chen and V. V. Dixit, "Debye-Huckel screening and the dissolution of the bound states", in Proc. of the 7th Winter Workshop on Nuclear Dynamics, Key West, Florida, 1991, edited by W. Bauer and J. Kapusta (World Scientific, Singapore, 1991) 238-241.

4. Wei R. Chen, Andrew Holt and Robert E. Nordquist, "Ablation of skin tissue by holmium YAG laser", SPIE Vol. 2134A, 342-351, 1994.

5. Wei R. Chen, Raleigh A. Holt and Robert E. Nordquist, "Laser hard tissue interaction: Energy transmission through human dental tissue using a holmium YAG laser", SPIE Vol. 2394, 68-77, 1995.

6. Wei R. Chen, Claudia L. Phillips, Kenneth E. Bartels, Robert L. Adams, and Robert E. Nordquist, "Indocyanine green in situ administration and photothermal destruction of tumor tissue using an 808 nm diode laser", SPIE Vol. 2681, 94-101, 1996.

7. Wei R. Chen, Baha Jassemnejad, Jason Crull, Edward Knobee, and Robert E. Nordquist, "Detection and characterization of chemical-induced abnormal tissue and rat tumor at different stages using fluorescence spectroscopy", SPIE Vol. 2679, 55-64, 1996.

8. Wei R. Chen, Kelly G. Wichert, Aaron K. Higgins, Kenneth E. Bartels, Robert L. Adams, and Robert E. Nordquist, "Effects of indocyanine green in treatment of murine mammary tumor by an 808 nm diode laser: an in vivo study", SPIE Vol. 2675, 114-121, 1996.

9. Wei R. Chen, David A. Okrongly, Robert L. Adams, and Robert E. Nordquist, “Laser-tissue photobiological interaction: a new mechanism for laser-sensitizer-immunoadjuvant treatment of metastatic cancers”, SPIE Vol. 2975, 290-297, 1997.

10. Li-hong Wang, Wei R. Chen and Robert E. Nordquist, “Theoretical studies of optimal light delivery for tumor treatment”, SPIE Vol. 2975, 84-95, 1997.

11. Wei R. Chen, Karen Robinson, Robert L. Adams, Anil Singhal and Robert E. Nordquist, “Anti-tumor immune responses induced by the treatment of photodynamic immunotherapy”, SPIE Vol. 3254, 27-34, 1998.

12. Robert E. Nordquist, John A. Nordquist, James C. Agee, Chad M. Blomquist and Wei R. Chen, “Morphological studies of metastatic mammary rat tumors after laser immunotherapy treatment”, SPIE Vol. 3254, 36-41, 1998.

13. Li-hong Wang, Guillermo Marquez, Robert E. Nordquist and Wei R. Chen, “Propagation and absorption of near-infrared laser light in photosensitizer-enhanced biological tissues”, SPIE Vol. 3254, 332-339, 1998.

14. J. Paul Wood, Kenneth E. Bartels, Ellen B. Davidson, Jerry Ritchey, Terry W. Lehenbauer, Robert E. Nordquist, and Wei R. Chen, “Laser-immunotherapy of canine and feline neoplasia”, SPIE 3245, 432-440 1998.

Wei R. Chen, Ph.D.

Page 46 of 80

15. Wei R. Chen and Robert E. Nordquist, “Control of metastatic mammary tumor by laser immunotherapy through local treatment”, SPIE 3548, 75-82, 1998.

16. Wei R. Chen, Ahmad El-Samad and Robert E. Nordquist, “Photothermal and immunological reactions against metastatic tumors using laser-photosensitizer-immunoadjuvant”, SPIE 3601, 75-81, 1999.

17. Hangyi Jiang, Hong Liu, Wei R. Chen and L Laurie L. Fajardo, "Positional accuracy and sensitivity in X-ray Stereo-image guidance", SPIE Proceedings, 3595, 178-185, 1999.

18. Hangyi Jiang, Hong Liu, and Wei R. Chen, "A calibration Technique for Monoplane Stereo X-ray systems in image guidance", SPIE Proceedings, Vol. 3911, 122-129, 2000.

19. (Invited Paper) Wei R. Chen, Hong Liu, Anil K. Singhal, and Robert E. Nordquist, “Passive adoptive transfer of antitumor immunity induced by laser-dye-immunoadjuvant treatment in a rat metastatic breast cancer model”, SPIE Proceedings, Vol. 3914, 26-32, 2000.

20. Andrea K. Ives, Wei R. Chen, Baha Jassemnejad, Kenneth E. Bartels, Hong Liu, John A. Nordquist and Robert E. Nordquist, “Laser-tissue photothermal interaction and tissue temperature change”, SPIE Proceedings, Vol. 3914, 94-101, 2000.

21. Wei R. Chen, Hong Liu, Ken E. Bartels and Robert E. Nordquist, “Functions of laser light, laser-absorbing dye and immunoadjuvants in Photo Dynamic Immuno Therapy”, SPIE Proceedings, Vol. 4224, 322-330, 2000.

22. Michael D. Lucroy, Wei R. Chen, Diana Sensney-Sears, Russell G. Higbee, and Kenneth E. Bartels, “Developing a subcutaneous murine breast cancer model for the evaluation of laser-induced hyperthermia”, Proceedings of the Veterinary Cancer Society 20th Annual Conference, October 15-18, 2000, Monterey, CA, p 87.

23. Wei R. Chen, “Optimizing laser immunotherapy of tumors”, Bulletin of TherapeuticAdvances, LeadDiscovery, http://www.leaddiscovery.fsnet.co.uk/target-discovery/abstracts/0436.html.

24. (Invited Paper) Wei R. Chen, Michael D. Lucroy, Hong Liu, Kenneth E. Bartels, Baha Jassemnejad, Shawn L. Barker, Punit Gandhi, and Robert E. Nordquist, “Immunoadjuvants in treatment of metastatic breast tumors using selective laser photothermal interaction”, SPIE Proceedings, Vol. 4257, 1-8, 2001.

25. Michael D. Lucroy, Wei R. Chen, Diana Sensney-Sears, Russell G. Higbee, and Kenneth E. Bartels, “Improved light delivery for chromophore-enhanced laser-induced hyperthermia in a subcutaneous murine breast cancer model”, SPIE Proceedings, Vol. 4244, 561-566, 2001.

26. Wei R. Chen, Hong Liu, and Robert E. Nordquist, “Mechanism of laser immunotherapy – role of immunoadjuvant and induction of anti-tumor immunity”, SPIE Proceedings, Vol. 4536, 82-89, 2002.

27. Wei R. Chen, Hong Liu, and Robert E. Nordquist, “Monitoring of laser treatment of rat tumors using digital x-ray imaging technique”, SPIE Proceedings, Vol. 4615, 117-126, 2002.

28. Fabrice Qunjj, Eric Potter, Wei R. Chen, and Hong Liu, “Impact of focal spot size on the spatial resolution of a digital x-ray imaging system for small animal studies”, SPIE Proceedings, Vol., 4615, 109-116, 2002.

29. Hangyi Jiang, Wei R. Chen, and Hong Liu, “Effect of window function on noise power spectrum measurements in digital x-ray imaging”, SPIE Proceedings, Vol., 4615, 91-97, 2002.

30. David Tang, Yuhua Li, Wei R. Chen, and Hong Liu, “Feasibility studies of high spatial resolution cardiac optical mapping system”, SPIE Proceedings, Vol., 4615, 127-136, 2002.

31. (Invited Paper) Wei R. Chen, Hong Liu, Roman Wolf, Michael D. Lucroy, and Robert E. Nordquist “Function of immunoadjuvants in laser immunotherapy for treatment of metastatic breast tumors in rats”, SPIE Proceedings, Vol., 4617, 11-17, 2002.

32. (Invited Paper) Thomas M. Cowan, Guangyu Liu, Sarah Simmons, Jeremy Real, Michael D. Lucroy, Kenneth E. Bartels, Robert E. Nordquist, and Wei R. Chen, “Selective photothermal

Wei R. Chen, Ph.D.

Page 47 of 80

interaction using near-infrared laser and laser-absorbing dye in gel phantom and chicken breast tissue”, SPIE Proceedings, Vol., 4617, 18-25, 2002.

3333.. (Invited Paper) Wei R. Chen, Jerry W. Ritchey, Kenneth E. Bartles, Michael D. Lucroy, Hong Liu, and Robert E. Nordquist, “Laser immunotherapy in treatment of metastatic prostate tumors in rats”, SPIE Proceedings, Vol., 4707, 165-172, 2002.

34. Christopher A. Bailey, Evan C. Lemley, and Wei R. Chen, “Theoretical Study of Selective Photo-Thermal Interactions Using Monte Carlo Simulations”, Proceedings of 16th National Conference on Undergraduate Research, 2002.

35. Sang Won Jeong, Fakhrildeen Albahadily, and Wei R. Chen, “Measurement of Optical Properties of Laser-Absorbing Dye Enhanced Gel Phantom for Selective Photothermal Interaction”, Proceedings of 16th National Conference on Undergraduate Research, 2002.

3366.. HemanthKumar Athiraman and Wei R. Chen, “Near-Infrared Laser and Laser-Absorbing Dye in Tissue Welding”, Proceedings of 16th National Conference on Undergraduate Research, 2002.

37. Jeremy W. Real and Wei R. Chen, “Optimization of selective energy absorption in tissue-simulating gelatin phantoms and chicken breast tissue”, Proceedings of 16th National Conference on Undergraduate Research, 2002.

38. (Invited Paper) Wei R. Chen, Hong Liu, Roman Wolf, Michael D. Lucroy, and Robert E. Nordquist, “Selective photothermal laser-tissue interaction with augmentation of immunoadjuvants in treatment of DMBA-4 metastatic mammary tumors in rats”, SPIE Proceedings, Vol. 4916, 37-42, 2002.

39. (Invited Paper) Wei R. Chen, Hong Liu, Michael D. Lucroy and Robert E. Nordquist, “Anti-tumor immunity induced by local photothermal-immunoadjuvant therapy in a poorly immunogenic metastatic tumor model”, SPIE Proceedings 4961, 18-23, 2003.

40. Thomas M. Cowan, Christopher A. Bailey, Hong Liu, and Wei R. Chen, “Optimization of operating parameters for selective photothermal interactions using 805-nm diode laser and indocyanine green”, SPIE Proceedings, Vol. 4961, 24-31, 2003.

41. David Y. Tang, Yuhua Li, Jianan Y. Qu, Sunny S. Po, Eugene S. Patterson, Wei R. Chen, Warren M. Jackman, and Hong Liu, “Preliminary study of a dual CCD based ratiometric optical mapping system”, SPIE Proceedings, Vol. 4958, 273-278, 2003.

42. (Invited Paper) Wei R. Chen, Kenneth E. Bartels, Jinghai Sun, Hong Liu, Robert E. Nordquist and Mladen Korbelik, “Dye-enhanced selective photothermal laser-tissue interaction and photodynamic therapy in combination with immunoadjuvant for cancer treatment”, SPIE Proceedings, Vol. 5254, 52-60, 2003.

43. (Invited Paper) Sang won Jeong, Hong Liu, and Wei R. Chen, “Temperature control in deep tumor treatment”, SPIE Proceedings, Vol. 5068, 210-216, 2003.

44. Qirong Zhang, Yuhua Li, Ben Steele, Wei R. Chen, Xizeng Wu, John Cheung, Hong Liu, "Contrast-detail analysis of a CMOS-based digital x-ray imaging system", The Proceedings of the ISCA 19th International Conference on Computers Applications (CATA-2004, ISBN: 1-880843-50-1), 51-54, 2004.

45. Qirong Zhang, Xizeng Wu, Wei R. Chen, John Cheung, and Hong. Liu, “Quantum efficiency of a digital x-ray imaging system for small animal studies”, SPIE Proceedings Vol. 5318, 94-98, 2004.

46. (Invited Paper) Wei R. Chen, Mladen Korbelik, Jinghai Sun, Hong Liu, and Robert E. Nordquist, “Enhancement of glycated chitosan in laser cancer treatment”, SPIE Proceedings, Vol. 5319, 80-86, 2004.

47. Vinson G. Liu, Chris A. Bailey, Jared Crochet, and Wei R. Chen, “Simulation of selective photothermal interaction with dye enhancement”, SPIE Proceedings, Vol. 5319, 101-107, 2004.

Wei R. Chen, Ph.D.

Page 48 of 80

48. (Invited Plenary Paper) Wei R. Chen, Mladen Korbelik, Kenneth E. Bartels, Hong Liu, and Robert E. Nordquist, “Laser Immunotherapy: A Novel Approach for Metastatic Tumors”, SPIE Proceedings, Vol. 5474, 25-32, 2004.

49. (Invited Paper) Wei R. Chen, Mladen Korbelik, Liu Hong, and Robert E. Nordquist, “Cancer Treatment by photothermal, photochemical and photobiological interactions”, SPIE Proceedings, Vol 5630, 1-7, 2005.

50. Eric Potter, Fabrice Ouandji, Yuhua Li, Pascal Laignier, Preeti Kshirsagar, Wei R. Chen and Hong Liu, “An Observer-Based Study of an X-Ray Imaging System for Small Animal Research”, SPIE Proceedings, Vol 5692, 44-50, 2005.

51. (Invited Paper) Wei R. Chen, Kenneth E. Bartels, Mladen Korbelik, Hong Liu, and Robert E. Nordquist, “Synergistic effects of laser and adjuvant therapies for cancer – Progress in the development of novel cancer treatment methods using combinations of photothermal, photochemical, immunotherapy and chemotherapy”, SPIE Proceedings, Vol 5695, 1-6, 2005.

52. Wei R. Chen, Kirill Andrienko, Kenneth E. Bartels, Steven D. Martin, Hong Liu, and Robert E. Nordquist, “Laser photothermal therapy in treatment of mouse melanoma”, SPIE Proceedings Vol 5695, 236-242, 2005.

53. (Plenary Paper) Wei R. Chen, Kenneth E. Bartels, Hong Liu and Robert E. Nordquist, “Induction and detection of immune responses by photoimmunotherapy”, SPIE Proceedings, Vol. 5771, 1-7, 2005.

54. Wei R. Chen, “Introduction”, SPIE Proceedings, Vol. 6087, xi-xiii, 2006. 55. (Invited Paper) Zheng Huang, Hong Liu, and Wei R. Chen, “Light and Immune Systems –

Activation of Immunological Activities”, SPIE Proceedings, Vol. 6087, 608701-1 – 608701-9, 2006.

56. Mark F. Naylor Robert E. Nordquist, T. Kent Teague, Lisa A. Perry, and Wei R. Chen, “In Situ Photoimmunotherapy for Melanoma: Preliminary Clinical Result”, SPIE Proceedings, Vol. 6087, 608709-1 – 608709-7, 2006.

57. Yichao Chen, Surya Gnyawali, Jeremy Bjorlie, Kirill Andrienko, Hong Liu, Yasvir A. Tesiram, Andrew Abbott, Rheal A. Towner, and Wei R. Chen, “Tissue temperature distribution measurement and laser immunotherapy for cancer treatment”, SPIE Proceedings, Vol. 6087, 60870H-1 – 60870H-11, 2006.

58. Wei R. Chen, Zheng Huang, Kirill Andrienko, Stefan Stefanov, Roman F. Wolf and Hong Liu, “Effects of surgery, immunization, and laser immunotherapy on a non-immunogenic metastatic tumor model”, SPIE Proceedings, Vol 6163, 61630E-1–61630E-6, 2006.

59. Yi Yang Zhou, Hans K. Pew, John Rong, Wei R. Chen, Laurie Fajardo, Xizeng Wu, and Hong Liu, "Phantom imaging with a prototype phase contrast radiography system", SPIE Proceedings, Vol 6163, 61630E-1– 61630E-7, 2006.

60. Abby Deans, Linda Hess, Michael Koss, Hong Liu, and Wei R. Chen, “Monitoring perfusion changes in laser-treated tumors using laser Doppler flowmetry”, SPIE Proceedings Vol 6084, 60840F1-60840F-8, 2006.

61. Lei Liu, Da Xing, Wei R. Chen, Tongsheng Chen, Yihui Pei, and Xuanjuan Gao, “Spatial and temporal changes in bid and bax subcellular localization during cisplatin-induced apoptosis”, Proc. Int. Symposium Biophotonics, Nanophotonics & Metamaterials, 167-170, 2006.

62. Molly Donovan, Da Zhang, Wei R. Chen, and Hong Liu, “The characterization of a phase contrast x-ray imaging prototype”, SPIE Proceedings, Vol. 6436, 643608(1-9), 2007.

63. Liangzhong Xiang, Da Xing, Huaimin Gu, Diwu Yang, Sihua Yang, Lvming Zeng, and Wei R. Chen, “Pulse laser integrated photodynamic therapy and photoacoustic imaging”, SPIE Proceedings, Vol. 64372B, 64372B(1-8), 2007.

Wei R. Chen, Ph.D.

Page 49 of 80

64. Mark F. Naylor, Robert E. Nordquist, T. Kent Teague, Lisa A. Perry, and Wei R. Chen, “In Situ Photoimmunotherapy for Melanoma: An Ongoing Phase I Clinical Trial”, SPIE Proceedings, Vol. 6438, 643807(1-9), 2007.

65. Wei R. Chen, Abdiwahab Mohamed, Mark, F. Naylor, Kenneth E. Bartels, Jerry W. Ritchey, Hong Liu, and Robert E. Nordquist, “Cellular immunological effects of laser irradiation and immunoadjuvant application”, SPIE Proceedings, Vol. 6438, 64380B(1-11), 2007.

66. Yichao Chen, Surya C. Gnyawali, Feng Wu, Hong Liu, Yasvir A. Tesiram, Andrew Abbott, Rheal A. Towner, and Wei R. Chen, “Tissue temperature distribution measurement by MRI and laser immunology for cancer treatment”, SPIE Proceedings, Vol. 6438, 64380C(1-12), 2007.

67. Surya C. Gnyawali, Yichao Chen, Feng Wu, Kenneth E. Bartels, Jerry W. Ritchey, James P. Wicksted, Hong Liu, and Wei R. Chen, “Determination of Surface Temperature Distribution in Biological Tissues during Laser-Immunotherapy”, SPIE Proceedings, Vol. 6438, 64380D(1-11), 2007.

68. Lei Liu, Da Xing, Yihui Pei, and Wei R. Chen, “Real-time single cell analysis of Bid cleavage and translocation in cisplatin-induced apoptosis”, SPIE Proceedings, Vol. 6438, 64380G(1-9), 2007.

69. Yichao Chen, Surya C. Gnyawali, Hong Liu, Yasvir A. Tesiram, Andrew Abbott, Rheal A. Towner, and Wei R. Chen, “MRI 3D tissue temperature distribution measurement”, SPIE Proceedings, Vol. 6438, 64380N(1-8), 2007.

70. Lei Liu, Da Xing, and Wei R. Chen, “Sub-cell FRET imaging for determination of signaling pathway of cell apoptosis during tumor therapy”, SPIE Proceedings, Vol. 6534 653402-(1-10), 2007.

71. Feifan Zhou, Da Xing, Wei R. Chen, “The single cell analysis of HSP70 expression on tumor cell surface induced by PDT in living cells”, SPIE Proceedings, Vol. 6534 65341G-(1-8), 2007.

72. Lei Liu, Da Xing, and Wei R. Chen, “Calpain mediates AIF-regulated caspase-independent pathway in cisplatin-induced apoptosis”’ SPIE Proceedings, Vol. 6826, 68261R-(1-8), 2007.

73. Fei-fan Zhou, Da Xing, and Wei R. Chen, “The HSP70 Release Regulates the Immune Response of Tumor Cells in PDT Treatment”, Proc. Intern. Conf. Compl. Med. Engineer., IEEE 07EX1719, 1009-1013 (2007).

74. Xingwei Wang, Bin Zheng, Shibo Li, John J. Mulvihill, Wei R. Chen and Hong Liu, “Development of an Integrated Computerized Scheme for Metaphase Chromosome Image Analysis: a Robustness Experiment”, SPIE Proceedings, Vol. 6855, 685507-(1-10), 2008.

75. Invited Paper Mark F. Naylor, Robert E. Nordquist, T. Kent Teaque, David A. Adelson, Lisa A. Perry, and Wei R. Chen, “In Situ Photoimmunotherapy for Advanced Cutaneous Melanoma”, SPIE Proceedings, Vol. 6857, 685702-(1-5), 2008.

76. Invited Paper Wei R. Chen, Mark F. Naylor, Robert E. Nordquist, T. Kent Teague, and Hong Liu, “Immunological responses induced by the combination of phototherapy and immunotherapy in the treatment of metastatic tumors”, SPIE Proceedings, Vol. 6857, 685707-(1-7), 2008.

77. Feifan Zhou, Da Xing, and Wei R. Chen, “PDT-apoptotic tumor cells induce macrophage immune response”, SPIE Proceedings, Vol. 6857, 68570C-(1-8), 2008.

78. Lei Liu, Da Xing, Wei R. Chen, Qingling Wan, and Feifan Zhou, “Spatial and Temporal Changes in Bax Subcellular Localization During NPe6-PDT-Induced Apoptosis”, SPIE Proceedings, Vol. 6857, 68570D-(1-7), 2008.

79. Yichao Chen, Robert E. Nordquist, Mark F. Naylor, Feng Wu, Hong, Liu, Yasvir A. Tesiram, Andrew Abbott, Rheal A. Towner, and Wei R. Chen, “The correlation study of temperature

Wei R. Chen, Ph.D.

Page 50 of 80

distribution with the immunology response under laser radiation”, SPIE Proceedings, Vol. 6857, 68570E-(1-7), 2008.

80. Marc C. Wood, Xingwei Wang, Bin Zheng, Shibo Li, Wei R. Chen, and Hong Liu, “Using Contrast Transfer Function to Evaluate the Effect of Motion Blur on Microscope Image Quality”, SPIE Proceedings, Vol. 6857, 68570F-(1-8), 2008.

81. Yuhua Li, John Rong, Robert Y. L. Chu, Da Zhang, Ann Archer, Laurie Fajardo, Wei R. Chen, Xizeng Wu, and Hong Liu, “Measurements of Imaging Parameters of a Phase Contrast X-ray Imaging Prototype”, SPIE Proceedings, Vol. 6857, 68570G-(1-6), 2008.

82. Surya C. Gnyawali, Kelvin Le, Henry Le, James P. Wicksted, Kenneth E. Bartels, Hong Liu, Yichao Chen, and Wei R. Chen, “Thermal Damage of Tissue during Near-Infrared Laser Irradiation with Assistance of Light-Absorbing Dye”, SPIE Proceedings, Vol. 6857, 68570O-(1-9), 2008.

83. Robert E. Nordquist, Mark F. Naylor, Hong Liu, Yichao Chen and Wei R. Chen, “Histological and morphological studies of immune responses induced by laser immunotherapy”, SPIE Proceedings, Vol. 6857, 68570Q-(1-8), 2008.

84. Yichao Chen, Gaurav Kumar, Jennifer Ellis, Feng Wu, Hong Liu, Rheal A. Towner, Wei R. Chen, “Gel phantom in selective laser phototherapy”, SPIE Proceedings, Vol. 6870, 687008-(1-9), 2008.

85. Lei Liu, Da Xing, Wei R. Chen, and Qingling Wan, “Measuring dynamics of Bid activation in living cells during NPe6-PDT-induced apoptosis”, Advances in Biomedical Photonics and Imaging, 144-149, 2008.

86. Lei Liu, Da Xing, and Wei R. Chen, “Calpain mediates AIF-regulated caspase-independent pathway in cisplatin-induced apoptosis”, Proc. of SPIE, 6826, U361-U368, 2008.

87. Wei R. Chen, Akhee Sarker, Hong Liu, Mark, F. Naylor, and Robert E. Nordquist, “Effects of immunostimulants in phototherapy for cancer treatment”, SPIE Proceedings, Vol. 7178, 71780A-(1-8), 2009.

88. Feifan Zhou, Wei R. Chen, and Sheng Song, “HSP70 inhibits Bax translocation during Photofrin-PDT apoptosis”, SPIE Proceedings, Vol. 7178, 71780D-(1-8), 2009.

89. Sheng Song, Da Xing, Feifan Zhou, and Wei R. Chen, “Effects of PDT-treated apoptotic cells on macrophages”, SPIE Proceedings, Vol. 7178, 71780O-(1-8), 2009.

90. Da Zhang, Xizeng Wu, Molly Wong, Yongshen Ni, John Rong, Wei R. Chen, and Hong Liu, “Error analysis in the measurement of x-ray photon fluence: an analysis on the uncertainty from energy calibration”, SPIE Proceedings, Vol. 7176, 71760I-(1-7), 2009.

91. Xingwei Wang, Bin Zheng, Shibo Li, Roy R. Zhang, Yuhua Li, John J. Mulvihill, Wei R. Chen, and Hong Liu, “Automated Segmentation and Analysis of Fluorescent in Situ Hybridization (FISH) Signals in Interphase Nuclei of Pap-smear Specimens”, SPIE Proceedings, Vol. 7176, 717609-(1-8), 2009.

92. Xiaosong Li, Mark F. Naylor, Robert E. Nordquist, T. Kent Teague, C. Anthony Howard, Cynthia Murray, and Wei R. Chen, “Preliminary results of a phase I/II clinical trial using in situ photoimmunotherapy combined with imiquimod for metastatic melanoma patients”, SPIE Proceedings, Vol. 7565, 756506-(1-8), 2010.

93. Tomas Hode, Maria C. Guerra, Gabriela L. Ferrel, John A. Lunn, Orn Adelsteinsson, Robert E. Nordquist, and Wei R. Chen, “Laser immunotherapy: initial results from a human breast cancer pilot trial”, SPIE Proceedings, Vol. 7565, 756507-(1-8), 2010.

94. Vivian, A. Chen, Henry, Le, Xiaosong, Li, Roman F. Wolf, Halie Ferguson, Akhee Sarkar, Hong Liu, Robert E. Nordquist, and Wei R. Chen, “Effect of laser immunotherapy and surgery on the treatment of mouse mammary tumors”, SPIE Proceedings, Vol. 7565, 756508-(1-8), 2010.

Wei R. Chen, Ph.D.

Page 51 of 80

95. Xianwang Wang, Da Xing, and Wei R. Chen, “Analysis of GFP-FOXO3a nuclear-cytoplasmic shuttling in ASTC-a-1 cells under growth factor stimulation”, SPIE Proceedings, Vol. 7565, 75650O-(1-8), 2010.

96. Invited Paper Xiaosong Li, Tomas Hode, Maria C. Guerra, Gabriela L. Ferrel, Robert E. Nordquist, and Wei R. Chen, “Laser immunotherapy for treatment of patients with advanced breast cancer and melanoma”, Journal of Physics: Conference Series, 276, 012023, 2011.

97. Xiaosong Li, Feifan Zhou, Henry Le, Roman F. Wolf, Eric Howard, Robert E. Nordquist, Tomas Hode, Hong Liu, and Wei R. Chen, “Mechanism study of tumor-specific immune responses induced by laser immunotherapy”, SPIE Proceedings, Vol. 7900, 790006 (1-10), 2011.

98. Robert E. Nordquist, Sally L. Bishop, Halie Ferguson, Melville B. Vaughan, Jessnie Jose, Katherine Kastl, Long Nguyen, Xiaosong Li, Hong Liu, and Wei R. Chen, “Immunohistochemical analysis of immune response in breast cancer and melanoma patients after laser immunotherapy”, SPIE Proceedings, Vol. 7900, 790007 (1-10), 2011.

99. Invited Paper Tomas Hode, Orn Adalstensson, Gabriela L. Ferrel, John A. Lunn, Maria Guerra, Xiaosong Li, Robert E. Nordquist, and Wei R. Chen, “Laser immunotherapy for the treatment of human breast cancer: 1-year follow-up results”, SPIE Proceedings, Vol. 7900, 79000p (1-10), 2011.

100. Invited Paper Daniel Figueroa, Chet Joshi, Roman F. Wolf, Jonny Walla, Jessica Goddard, Mallory Martin, Stanley D. Kosanke, Fred S. Broach, Sean Pontius, Destiny Brown, Xiaosong Li, Eric Howard, Robert Nordquist, Tomas Hode, Hong Liu, and Wei R. Chen, “Interstitial laser immunotherapy for treatment of metastatic tumors in rats”, SPIE Proceedings, Vol. 7900, 79000A (1-11), 2011.

101. Kelvin Le, Chet Joshi, Daniel Figueroa, Jessica Goddard, Xiaosong Li, Rheal A. Towner, Debra Saunders, Nataliya Smith, Hong Liu, Tomas Hode, Robert E. Nordquist, and Wei R. Chen, “Photothermal effect in tissues induced by interstitial irradiation of near infrared laser with a cylindrical diffuser”, SPIE Proceedings, Vol. 7900, 79000B (1-14), 2011.

102. Yuchen Qiu, Xiaodong Chen, Yuhua Li, Zheng Li, Bin Zheng, Shibo Li, Wei R. Chen, and Hong Liu, “The impact of the depth of field to cytogenetic image quality in scanning microscopy”, SPIE Proceedings, Vol. 7900, 79000D (1-5), 2011.

103. Sheng Song, Fei-fan Zhou, Si-hua Yang, and Wei R. Chen, “Molecular mechanism of PDT-induced apoptotic cells stimulation NO production in macrophages”, SPIE Proceedings, Vol. 7900, 790008 (1-10), 2011.

104. Feifan Zhou, Da Xing, and Wei R. Chen, “Direct imaging the subcellular localization of single-walled carbon nanotubes”, SPIE Proceedings, Vol. 7900, 79000E (1-8), 2011.

105. Mark F. Naylor, Henry Le, Xiaosong Li, Robert E. Nordquist, Tomas Hode, Hong Liu, and Wei R. Chen, “Long-term effects of laser-imiquimod combination in the treatment of late-stage melanoma patients”, SPIE Proceedings, Vol. 8224, 822406 (1-8), 2012.

106. Chet Joshi, Jessnie Jose, Daniel Figueroa, Jessica Goddard, Xiaosong Li, Hong Liu, Robert E. Nordquist, Tomas Hode, and Wei R. Chen, “Interstitial laser irradiation of metastatic mammary tumors in combination with intratumoral injection of immunoadjuvant”, SPIE Proceedings, Vol. 8224, 822408 (1-10), 2012.

107. Jessica Goddard, Jessnie Jose, Daniel Figueroa, Kelvin Le, Hong Liu, Robert. E. Nordquist, Tomas Hode, and Wei R. Chen, “Magnetic resonance thermometry for monitoring photothermal effects of interstitial laser irradiation”, SPIE Proceedings, Vol. 8224, 82240A (1-11), 2012.

108. Yuchen Qiu, Xiaodong Chen, Zheng Li, Yuhua Li, Wei R. Chen, Bin Zheng, Shibo Li, and Hong Liu, “An Automatic Scanning Method for High Throughput Microscopic System to

Wei R. Chen, Ph.D.

Page 52 of 80

Facilitate Medical Genetic Diagnosis: An Initial Study”, SPIE Proceedings, Vol. 8224, 82240E (1-5), 2012.

109. Melville. B. Vaughan, Chelsea L. Spencer, Jessica Goddard, Jessnie Jose, and W. R. Chen, “Effect of near-infrared lasers on myofibroblast differentiation and contraction,” SPIE Proceedings, Vol. 8224, 82240F (1-6), 2012.

110. Ohkee K. Nag, Han Young Woo, and Wei R. Chen, “Cellular internalization of a membrane binding two-photon probe by a complex of anionic diblock copolymer and cationic surfactant,” SPIE Proceedings, Vol. 8224, 82240G (1-6), 2012.

111. Xue-mei Chi, Jie Cao, Shu-nan Wang, Chang-li Du, Wei R. Chen, and Yue-qing GU, “Synthesis and characterization of NIR light-responsive LbL nanocapsules”, SPIE Proceedings, Vol. 8224, 82240J (1-9), 2012.

112. Jie Cao, Shunan Wan, Junmei Tian, Xuemei Chi, Changli Du, Dawei Deng, Wei R. Chen, and Yueqing Gu, “Synthesis of dimeric cyclic RGD based near-infrared probe for in vivo tumor diagnosis”, SPIE Proceedings, Vol. 8224, 82240T (1-12), 2012.

113. Junmei-Tian, Zhenzhen-Tu, Wei R. Chen, and Yueqing-Gu, “ERβ regulates miR-21 expression and inhibits invasion and metastasis in cancer cells”, SPIE Proceedings, Vol. 8224, 82240U (1-9), 2012.

114. Sisi Cui, Hongyan Zhu, Haiyan Chen, Junmei Tian, Wei R. Chen, Yueqing Gu, “Surface modification of upconversion nanoparticles with amphiphilic chitosan for cancer cell imaging”, SPIE Proceedings, Vol. 8224, 82240V (1-9), 2012.

115. Sheng Song, Feifan Zhou, Wei R. Chen, and Da Xing, “Direct imaging of macrophage activation during PDT treatment”, SPIE Proceedings, Vol. 8329, 83290M(1-10), 2012.

116. Cuixia Lu, Feifan Zhou, Wei R. Chen, and Da Xing, “Mechanistic study of macrophage activation by LPS stimulation using fluorescence imaging techniques”, SPIE Proceedings, Vol. 8329, 83290N(1-10), 2012.

117. Liqiang Ren, Yuchen Qiu, Zheng Li, Yuhua Li, Bin Zheng, Shibo Li, Wei R. Chen, and Hong Liu, “A preliminary investigation: the impact of microscopic condenser on depth of field in cytogenetic imaging”, SPIE Proceedings, Vol. 8580, 85800K(1-6), 2013.

118. Cody Bahavar, Jessica Goddard, Allie Sikes, Ellen Boarman, Robert E. Nordquist, Tomas Hode, Hong Liu, and Wei R. Chen, “Effects of interstitial laser immunotherapy for the treatment of metastatic cancer”, SPIE Proceedings, Vol. 8582, 858207(1-7), 2013.

119. Joseph T. Acquaviva III, Wei R. Chen and Melville B. Vaughan, “Biological effects of near-infrared lasers on fibroblast cellular differentiation, proliferation and contraction”, SPIE Proceedings, Vol. 8582, 858208(1-8), 2013.

120. Zhifang Li, Yubing Liu, Hui Li, Wei R. Chen, Haiyu Chen, and Huan Wang, “Monitoring tissue temperature for photothermal cancer therapy based on photoacoustic imaging: a pilot study”, SPIE Proceedings, Vol. 8582, 858209(1-7), 2013.

121. Sisi Cui, Haiyan Chen, Zhiyu Qian, Wei R. Chen, and Yueqing Gu, “Folate receptor-mediated tumor-targeted upconversion nanocomplex for photodynamic therapy triggered by near-infrared light”, SPIE Proceedings, Vol. 8582, 85820A(1-9), 2013.

122. Ryan T. Griswold, Brock Henderson, Jessica Goddard, Yongqian Tan, Tomas Hode, Hong Liu, Robert E. Nordquist, and Wei R. Chen, “Photothermal Effects of Immunologically Modified Carbon Nanotubes”, SPIE Proceedings, Vol. 8582, 85820C(1-6), 2013.

123. Muhammad U Ghani, Di Wu, Yuhua Li, Minhua Kang, Wei R Chen, Xizeng Wu, and Hong Liu, “Quantitative Analysis of Contrast to Noise Ratio Using a Phase Contrast X-ray Imaging Prototype”, SPIE Proceedings, Vol. 8582, 85820H(1-6), 2013.

Wei R. Chen, Ph.D.

Page 53 of 80

124. Yuchen Qiu, Yuhua Li, Liqiang Ren, Wei R. Chen, Bin Zheng, Shibo Li, and Hong Liu, “Objective evaluation of the microscopic image sharpness for diagnostic metaphase chromosomes”, SPIE Proceedings, Vol. 8582, 85820I(1-5), 2013.

125. Di Wu, Muhammad U. Ghani, Hui Miao, Yuhua Li, Wei R. Chen, Xizeng Wu, and Hong Liu, “A Phantom Study to Characterize the Imaging Quality of a Phase-contrast Tomosynthesis Prototype”, SPIE Proceedings, Vol. 8582, 85820J(1-5), 2013.

126. Joseph T. Acquaviva III, Feifan Zhou, Ellen Boarman, and Wei R. Chen, “Anti-tumor response with immunologically modified carbon nanotubes and phototherapy”, SPIE Proceedings, Vol. 8582, 85820L(1-8), 2013.

127. Y-L Chen, W-R Chen, R-S Liu, F-Y Yang, C-Y Wang, and Y-J Lee, “Using immunoadjuvant agent glycated chitosan to enhance anti-cancer stem like cell immunity induced by HIFU”, SPIE Proceedings, Vol. 8582, 85820R(1-4), 2013.

128. Li Ding, Wei R. Chen, Yueqing Gu, “A bispecific peptide based near-infrared probe for in vivo tumor diagnosis”, SPIE Proceedings, Vol. 8582, 85820T(1-6), 2013.

129. Yuxiang Ma, Yuqi Chen, Sisi Cui, Juan Zhao, Wei R. Chen, and Yueqing Gu, “Preparation and characterization of a drug carrier for hepatocellular carcinoma targeting”, SPIE Proceedings, Vol. 8582, 85820U(1-6), 2013.

130. Aqin Wang, Yuqi Chen, Wei R. Chen, and Yueqing Gu, “Novel 2DG-based harmine derivatives for targeted cancer therapy”, SPIE Proceedings, Vol. 8582, 85820V(1-7), 2013.

131. Robert E. Nordquist, Cody Bahavar, Feifan Zhou, Tomas Hode, Wei R. Chen, Xiaosong Li, and Mark F. Naylor, “Laser assisted immunotherapy (LIT) for chemotherapy-resistant neoplasms: recent case reports”, SPIE Proceedings, Vol. 8944, Biophotonics and Immune Responses IX, 894406 (1-7), 2014.

132. Joseph T. Acquaviva, Ethan W. Wood, Aamr Hasanjee, Wei R. Chen, Melville B. Vaughan, “Effects of laser immunotherapy on tumor microenvironment ”, SPIE Proceedings, Vol. 8944, Biophotonics and Immune Responses IX, 894407 (1-8), 2014.

133. Cody F. Bahavar, Joseph T. Acquaviva, Sheyla Rabei, Allie Sikes, Robert E. Nordquist, Tomas Hode, Hong Liu, and Wei R. Chen, "Effects of cyclophosphamide on laser immunotherapy for the treatment of metastatic cancer", SPIE Proceedings, Vol. 8944, Biophotonics and Immune Responses IX, 894408 (1-6), 2014.

134. Sean M. Laverty, Bryan A. Dawkins, and Wei R. Chen, "Laser immunotherapy and the tumor-immune system interaction: a mathematical model and analysis", SPIE Proceedings, Vol. 8944, Biophotonics and Immune Responses IX, 894409 (1-9), 2014.

135. Di Wu, Aimin Yan, Yuhua Li, Wei R. Chen, Xizeng Wu, and Hong Liu, "Phantom study based on a high-energy in-line phase contrast tomosynthesis prototype", SPIE Proceedings, Vol. 8944, Biophotonics and Immune Responses IX, 89440G (1-10), 2014.

136. Liqiang Ren, Di Wu, Yuhua Li, Wei R. Chen, and Hong Liu, "Background estimation methods for quantitative x-ray fluorescence analysis of gold nanoparticles in biomedical applications", SPIE Proceedings, Vol. 8944, Biophotonics and Immune Responses IX, 89440H (1-6), 2014.

137. Gabriela L. Ferrel, Feifan Zhou, Xiaosong Li, Tomas Hode, Robert E. Nordquist, Luciano Alleruzzo, and Wei R. Chen, "Effects of laser immunotherapy on late-stage, metastatic breast cancer patients in a Phase II clinical trial", SPIE Proceedings, Vol. 8944, Biophotonics and Immune Responses IX, 89440I (1-9), 2014.

138. Feifan Zhou. Sheng Song, and Wei R. Chen, "Special antitumor immune effects of laser immunotherapy with SWNT-GC", SPIE Proceedings, Vol. 8944, Biophotonics and Immune Responses IX, 89440J (1-8), 2014.

Wei R. Chen, Ph.D.

Page 54 of 80

139. Zhifang Li, Xiaona Lin, Hui Li, and Wei R. Chen, "Application of OCT elastography for diagnosis of thyroid hydatoncus", SPIE Proceedings, Vol. 8944, Biophotonics and Immune Responses IX, 89440N (1-9), 2014.

140. Wei R. Chen, Feifan Zhou, Brock Henderson, Bailey Vasquez, Hong Liu, Tomas Hode, and Robert E. Nordquist, "Mechanistic studies of systemic immune responses induced by laser-nanotechnology ", SPIE Proceedings, Vol. 8944, Biophotonics and Immune Responses IX, 89440U (1-6), 2014.

141. Sheng Song, Feifan Zhou, and Wei R. Chen, "Low-power laser irradiation (LPLI) attenuates microglial cytotoxicity through the activation of Src pathway", SPIE Proceedings, Vol. 8944, Biophotonics and Immune Responses IX, 89440Y (1-13), 2014.

142. Wei R. Chen, "Biophotonics and Immune Responses – The 10-Year Journey", SPIE Proceedings, Vol. 9324, Biophotonics and Immune Responses X, ix-xv, 2015.

143. Mladen Korbelik, Judit Banáth, Evaldas Čiplys, Zdzislaw Szulc, Alicija Bielawska, and Wei R. Chen, "Activity of glycated chitosan and other adjuvants to PDT vaccines", SPIE Proceedings, Vol. 9324, Biophotonics and Immune Responses X, 932407 (1-5), 2015.

144. Jie Ji, Zhixia Fan, Feifan Zhou, Xiaojie Wang, Lei Shi, Haiyan Zhang, Peiru Wang, Degang Yang, Linglin Zhang, Xiuli Wang, and Wei R. Chen, "ALA-PDT mediated DC vaccine for skin squamous cell carcinoma", SPIE Proceedings, Vol. 9324, Biophotonics and Immune Responses X, 93240A (1-10), 2015.

145. Cody F. Bahavar, Feifan Zhou, Aamr M. Hasanjee, Connor L. West, Robert E. Nordquist, Thomas Hode, Hong Liu, and Wei R. Chen, "The immunological response created by interstitial and non-invasive laser immunotherapy", SPIE Proceedings, Vol. 9324, Biophotonics and Immune Responses X, 93240D (1-8), 2015.

146. Feifan Zhou, Aamr Hasanjee, Austin Doughty, Connor West, Hong Liu, and Wei R. Chen, "Photo-nano immunotherapy for metastatic breast cancer using synergistic single-walled carbon nanotubes and glycated chitosan", SPIE Proceedings, Vol. 9324, Biophotonics and Immune Responses X, 93240L (1-5), 2015.

147. Joseph T. Acquaviva III, Aamr M. Hasanjee, Cody F. Bahavar, Feifan Zhou, Hong Liu, Eric W. Howard, Liz C. Bullen, Ricardo P. Silvy, and Wei R. Chen, "Anti-tumor Response Induced by Immunologically Modified Carbon Nanotubes and Laser Irradiation using Rat Mammary Tumor Model", SPIE Proceedings, Vol. 9324, Biophotonics and Immune Responses X, 932415 (1-6), 2015.

148. Chun-Yuan Chang, Jyh-Der Leu, Chung-Yi Wang, Wei R. Chen, and Yi-Yang Lee, "The combination of radiotherapy and immunotherapy using glycated chitosan as an immunological stimulant", SPIE Proceedings, Vol. 9324, Biophotonics and Immune Responses X, 932416 (1-5), 2015.

149. Di Wu, Molly D. Wong, Yuhua Li, Wei R. Chen, Xizeng Wu, and Hong Liu, "DQE Characterization of a High-energy In-line Phase Contrast Prototype under Different kVp and Beam Filtration", SPIE Proceedings, Vol. 9324, Biophotonics and Immune Responses X, 932418 (1-10), 2015.

150. Aamr Hasanjee, Elivia Layton, Kegan Silk, Cody Bahavar, Connor West, Austin Doughty, Feifan Zhou, and Wei R. Chen, “Photothermal effects of gold nanorods and indocyanine green on tumor cells using an 805-nm diode laser”, SPIE Proceedings, Vol. 9709, Biophotonics and Immune Responses XI, 2016 (in press).

151. Tomas Hode, Lu Alleruzzo, Joseph Raker, Siu Kit “Samuel” Lam, Robert E. Nordquist, and Wei R. Chen, “Development of inCVAX for treatment of metastatic cancers – Milestones of a biotech company”, SPIE Proceedings, Vol. 9709, Biophotonics and Immune Responses XI, 2016 (in press).

Wei R. Chen, Ph.D.

Page 55 of 80

152. Samuel Siu Kit Lam, Feifan Zhou, Tomas Hode, Robert Nordquist, Luciano Alleruzzo, Joseph Raker, and Wei R. Chen, “InCVAX, a Novel In Situ Autologous Cancer Vaccine”, SPIE Proceedings, Vol. 9709, Biophotonics and Immune Responses XI, 2016 (in press).

153. Cody F. Bahavar, Feifan Zhou, Aamr M. Hasanjee, Wei R. Chen, and Melville Vaughan, “The effects of laser immunotherapy on cancer cell migration”, SPIE Proceedings, Vol. 9709, Biophotonics and Immune Responses XI, 2016 (in press).

154. Aamr Hasanjee, Elivia Layton, Kegan Silk, Cody Bahavar, Connor West, Austin Doughty, Feifan Zhou, and Wei R Chen, “In vivo photothermal effects of 808 nm gold nanorods and indocyanine green on metastatic pancreatic tumor model using an 805 nm diode laser”, SPIE Proceedings, Vol. 9709, Biophotonics and Immune Responses XI, 2016 (in press).

Wei R. Chen, Ph.D.

Page 56 of 80

PRESENTATIONS

Oral Presentations 1. Wei R. Chen and Rudolph C. Hwa, "Cross sections and multiplicity distributions with

minijets", presented at Shandong Workshop on Multiparticle Production, Jinan, China, 1987. 2. Wei R. Chen, "Massive cluster decay in multiparticle production", presented at Conference of

Particle and Fields, Houston, TX, January 1990. 3. Wei R. Chen and V. V. Dixit, "Debye-Huckel screening and the dissolution of the bound

states", presented at the 7th Winter Workshop on Nuclear Dynamics, Key West, Florida, 1991. 4. Wei R. Chen, Andrew Holt and Robert E. Nordquist, "Ablation of skin tissue by holmium

YAG laser", presented at SPIE/Photonics West'94, Los Angeles, CA, January 1994. 5. Wei R. Chen, Raleigh A. Holt and Robert E. Nordquist, "Laser hard tissue interaction: Energy

transmission through human dental tissue using a holmium YAG laser", presented at SPIE/Photonics West'95, San Jose, CA, January 1995.

6. Wei R. Chen, Robert L. Adams, Claudia L. Phillips, and Robert E. Nordquist, "Indocyanine green in situ administration and photothermal destruction of tumor tissue using an 808 nm diode laser", presented at SPIE/Photonics West'96, San Jose, CA, January 1996.

7. Wei R. Chen, Baha Jassemnejad, Jason Crull, Edward Knobee, and Robert E. Nordquist, "Detection and characterization of chemical-induced abnormal tissue and rat tumor at different stages using fluorescence spectroscopy", presented at SPIE/Photonics West'96, San Jose, CA, January 1996.

8. Wei R. Chen, Kelly, G. Wichert, Aaron K. Higgins, Kenneth E. Bartels, Robert L. Adams, and Robert E. Nordquist, "Effects of indocyanine green in treatment of murine mammary tumor by an 808 nm diode laser: an in vivo study", presented at SPIE/Photonics West'96, San Jose, CA, January 1996.

9. Wei R. Chen, Robert L. Adams, David A. Okrongly and Robert E. Nordquist, “Laser-tissue photobiological interaction: a new mechanism for laser-sensitizer treatment of lesions”, presented at SPIE/Photonics West'97, San Jose, CA, January 1997.

10. Li-hong Wang, Wei R. Chen and Robert E. Nordquist, “Theoretical studies of optimal light delivery for tumor treatment”, presented at SPIE/Photonics West'97, San Jose, CA, January 1997.

11. Wei R. Chen, Karen Robinson, Robert L. Adams, Anil Singhal and Robert E. Nordquist, “Anti-tumor immune responses induced by the treatment of photodynamic immunotherapy”, presented at SPIE/Photonics West'98, San Jose, CA, January 1998.

12. Robert E. Nordquist, John A. Nordquist, James C. Agee, Chad M. Blomquist and Wei R. Chen, “Morphological studies of metastatic mammary rat tumors after laser immunotherapy treatment”, presented at SPIE/Photonics West'98, San Jose, CA, January 1998.

13. Li-hong Wang, Guillermo Marquez, Robert E. Nordquist and Wei R. Chen, “Propagation and absorption of near-infrared laser light in photosensitizer-enhanced biological tissues”, presented at SPIE/Photonics West'98, San Jose, CA, January 1998.

14. J. Paul Wood, Kenneth E. Bartels, Ellen B. Davidson, Jerry Ritchey, Terry W. Lehenbauer, Robert E. Nordquist, and Wei R. Chen, “Laser-immunotherapy of canine and feline neoplasia”, presented at SPIE/Photonics West'98, San Jose, CA, January 1998.

15. Wei R. Chen and Robert E. Nordquist, “Control of metastatic mammary tumor by laser immunotherapy through local treatment”, presented at Photonics China‘98, Bejing, China, September 1998.

Wei R. Chen, Ph.D.

Page 57 of 80

16. Wei R. Chen, Ahmad El-Samad and Robert E. Nordquist, “Photothermal and immunological reactions against metastatic tumors using laser-photosensitizer-immunoadjuvant”, presented at SPIE/Photonics West'99, San Jose, CA, January 1999.

17. Wei R. Chen, Hong Liu, Wei Yue, “Monitoring of laser treatment of rat mammary tumors using x-ray imaging techniques”, Presented at SPIE/Photonics West'99, San Jose, CA, January, 1999

18. Wei R. Chen, Hong Liu, Wei Yue, “Monitoring of laser treatment of rat mammary tumors using x-ray imaging techniques”, Presented at SPIE/Photonics West'99, San Jose, CA, January, 1999

19. Invited talk Wei R. Chen, "Passive transfer of antitumor immunity induced by laser", presented at SPIE/Biomedical Optics'99, Wuhan, China, October, 1999.

20. Hangyi Jiang, Hong Liu, Wei R. Chen, "A calibration Technique for Monoplane Stereo X-ray systems in image guidance", presented at SPIE/Photonics West'2000, San Jose, CA, January 2000.

21. Invited talk Wei R. Chen, Hong Liu, Kenneth E, Bartels, Jerry W. Ritchey, John A. Nordquist, and Robert E. Nordquist "Laser immunotherapy treatment on rats with prostatic tumors and lung metastases", presented at SPIE/Photonics West'2000, San Jose, CA, January 2000.

22. Invited talk Wei R. Chen, Hong, Liu, Anil K. Singhal, Robert E. Nordquist, “Passive adoptive transfer of antitumor immunity induced by laser-dye-immunoadjuvant treatment in a rat metastatic breast cancer model”, presented at SPIE/Photonics West'2000, San Jose, CA, January 2000.

23. Andrea K. Ives, Wei R. Chen, Baha Jassemnejad, Kenneth E. Bartels, Hong Liu, John A. Nordquist and Robert E. Nordquist, “Laser-tissue photothermal interaction and tissue temperature change”, presented at SPIE/Photonics West'2000, San Jose, CA, January 2000.

24. Invited talk Wei R. Chen, Hong Liu, Ken E. Bartels and Robert E. Nordquist, “Functions of laser light, laser-absorbing dye and immunoadjuvants in Photo Dynamic Immuno Therapy”, presented at Biomedical Photonics and Optoeletronic Imaging, Beijing, China, November, 2000.

25. Invited talk Wei R. Chen, Michael D. Lucroy, Hong Liu, Kenneth E. Bartels, Baha Jassemnejad, Shawn L. Barker, Punit Gandhi, and Robert E. Nordquist, “Immunoadjuvants in treatment of metastatic breast tumors using selective laser photothermal interaction”, presented at Photonics West’2001, San Jose, CA, January 2001.

26. Michael D. Lucroy, Wei R. Chen, Diana Sensney-Sears, Russell G. Higbee, and Kenneth E. Bartels, “Developing a subcutaneous murine breast cancer model for the evaluation of laser-induced hyperthermia”, presented at the Veterinary Cancer Society 20th Annual Conference, October 15-18, 2000, Monterey, CA, p 87.

27. Michael D. Lucroy, Wei R. Chen, Diana Sensney-Sears, Russell G. Higbee, and Kenneth E. Bartels, “Improved light delivery for chromophore-enhanced laser-induced hyperthermia in a subcutaneous murine breast cancer model”, presented at Photonics West’2001, San Jose, CA, January 2001.

28. Invited talk Wei R. Chen, “A novel approach for treatment of metastatic tumors using selective hyperthermia and immunological stimulation”, Biomedical Engineering Lecture Series, Oregon Medical Laser Center, Portland, Oregon, June 11, 2001.

29. Invited talk Wei R. Chen, “Antitumor Immunity Induced by Combined Selective Photothermal and Immunological Reactions”, Biomedical Engineering Seminar, Texas A&M University, College Station, Texas, July 12, 2001.

Wei R. Chen, Ph.D.

Page 58 of 80

30. Wei R. Chen, “Mechanism of Laser Immunotherapy – Selective Photothermal Interaction and Induction of Anti-Tumor Immunity Using Immunoadjuvant”, Sigma Xi Meeting, University of Central Oklahoma, Edmond, Oklahoma, September 13, 2001.

31. Invited talk Wei R. Chen, Hong Liu, and Robert E. Nordquist, “Mechanism of Laser Immunotherapy – Role of Immunoadjuvant and Induction of Anti-Tumor Immunity", International Workshop on Photonics and Imaging in Biology and Medicine (PIBM’01), October 8-10, 2001, Wuhan, China.

32. Invited talk Wei R. Chen, “Novel Cancer Treatment”, School of Aerospace and Mechanical Engineering, University of Oklahoma, Summer, 2001, Norman, Oklahoma.

33. Wei R. Chen, “Synergism in Research and Education – Constructive effects of multiple components in cancer treatment and in biomedical engineering program”, Sigma Xi Award Presentation, UCO, 2002

34. Wei R. Chen, “Mechanism of Laser Immunotherapy – Selective Photothermal Interaction and Induction of Anti-Tumor Immunity Using Immunoadjuvant”, Sigma Xi Research Seminar, UCO, 2002.

35. Invited talk Wei R. Chen, Hong Liu, and Robert E. Nordquist, “Long-term tumor resistance in laser-immunotherapy cured rats and the function of immunoadjuvant”, Photonics West; January 2002, San Jose, CA

36. Wei R. Chen, Thomas M. Cowan, Sarah Simmons, Guangyu Liu, “Optimization of laser and dye parameters for selective photothermal interaction using gel phantom and cadaveric chicken breast tissue”, Photonics West; January 2002, San Jose, CA

37. Wei R. Chen, “Dynamic monitoring of laser immunotherapy for metastatic tumors in rats”, Photonics West; January 2002, San Jose, CA

38. Invited talk Wei R. Chen, “Laser immunotherapy in treatment of metastatic tumors: synergism between photophysical and immunological interactions”, Saratov International Workshop on Biophotonics – SIWB-02, June, 2002, Saratov, Russia

39. Invited talk Wei R. Chen, “Near-infrared lasers in treatment of deep, metastatic tumors using dye-enhanced selective photothermal interaction”, Conference on Lasers, Applications, and Technologies (LAT) 2002, June, 2002, Moscow, Russia.

40. Invited talk Wei R. Chen, “Laser Immunotherapy: A Novel Approach for Treatment of Metastatic Tumors – Synergism between Photophysical and Immunological Reactions”, Wellman Laboratories of Photomedicine, Department of Dermatology, Harvard Medical School, September 3, 2002, Boston, MA.

41. Invited talk (Internet) Wei R. Chen, “Temperature control in deep tumor treatment”, Saratov Fall Meeting 2002, October 1-4, 2002, Saratov, Russia.

42. Invited talk Wei R. Chen, Hong Liu, Roman F. Wolf, Michael D. Lucroy, and Robert E. Nordquist, “Selective photothermal laser-tissue interaction with augmentation of immunoadjuvants in treatment of DMBA-4 metastatic mammary tumors in rats”, International Conference Optics in Health Care and Biomedical Optics: Diagnostics and Treatment, Photonics Asia; October 14-18, 2002, Shanghai, China

43. Sang-Won Jeong and Wei R. Chen, “Selective photothermal laser-tissue interaction using chicken breast tissue and rat tumors”, 91st Annual Technical Meeting, Oklahoma Academy of Science, November 1, 2002, Edmond, Oklahoma.

44. Hemanthkumar Athiraman and Wei R. Chen, “Laser tissue welding”, 91st Annual Technical Meeting, Oklahoma Academy of Science, November 1, 2002, Edmond, Oklahoma.Invited talk Wei R. Chen, “Treatment of Metastatic Tumors”, Institute of Laser Life Science, South China Normal University, January, 2003, Guangzhou, China.

Wei R. Chen, Ph.D.

Page 59 of 80

46. Invited talk Wei R. Chen, Michael D. Lucroy, Roman F. Wolf, Hong Liu, and Robert E. Nordquist “Anti-tumor immunity induced by local photothermal-immunoadjuvant therapy in a poorly immunogenic metastatic tumor model”, SPIE International Conference of Laser-Tissue Interaction XIV, Photonics West 2003, January 2003, San Jose, CA.Wei R. Chen, Thomas M. Cowan, Chris Bailey, and Hong Liu, “Optimization of operating parameters for selective photothermal interactions using 805-nm diode laser and indocyanine green”, SPIE International Conference of Laser-Tissue Interaction XIV, Photonics West 2003, January 2003, San Jose, CA.Invited Paper Eric Potter, Fabrice Ouandji, Yuhua Li, Pascal Laignier, Preeti Kshirsagar, Wei R. Chen and Hong Liu, “An Observer-Based Study of an X-Ray Imaging System for Small Animal Research”, Photonics West 2003, January 2003, San Jose, CA.

49. David Y. Tang, Yuhua Li, Jianan Y. Qu, Sunny S. Po, Eugene S. Patterson, Wei R. Chen, Warren M. Jackman, and Hong Liu, “Preliminary study of a dual CCD based ratiometric optical mapping system”, Photonics West 2003, January 2003, San Jose, CA.Award Lecture Wei R. Chen, “Treatment of Metastatic Tumors Using Synergistic Effects of Laser-Tissue Interaction and Immunological Stimulation”, Lecture, Presentation of Distinguished Scholar Award, American Association of University Professors – UCO Chapter, April 3, 2003, University of Central Oklahoma.Invited talk Wei R. Chen, “Optimization of Dye-Enhanced Selective Photothermal Laser-Tissue Interaction”, Biophotonics Pacific Rim PIBM/MDM 2003 (Photonics and Imaging in Biology and Medicine / Multi-Dimensional Microscopy) June 8 to 11, 2003, Wuhan, China.Invited Lecture Wei R. Chen, “Photophysical Interactions and Immunological Stimulation in Cancer Treatment”, Department of Physiology, The University of Texas Health Science Center at San Antonio, September 8, 2003, San Antonio, Texas.

53. Plenary lecture (Internet) Wei R. Chen, “Laser Immunotherapy: A Novel Approach for Metastatic Tumors”, Saratov Fall Meeting 2003: Optical Technologies in Biophysics and Medicine V, October 9, 2003, Saratov, Russia.

54. Invited talk Wei R. Chen, “Immunoadjuvants in selective photo-hyperthermia and photodynamic therapy for cancer treatment”, International Conference on Biophotons and Biophotonics, October 12-16, 2003, Beijing, China.Colloquium Speaker Wei R. Chen, “Laser Treatment of Cancers with Augmentation of Immunological Stimulations”, November 6, 2003, Department of Physics, Oklahoma State University, Stillwater, Oklahoma.Wei R. Chen, Suman Shivakoti, Sang Won Jeong and Hemanthkumar Athiraman, “Laser-Tissue Welding and Wound Healing”, 92nd Annual Technical Meeting, Oklahoma Academy of Science, November 7, 2003, Chickasha, Oklahoma.

57. Tiffany Thoren, Sang Won Jeong, Kirill Andrienko and Wei R. Chen, “Laser Applications in Cancer Treatment”, 92nd Annual Technical Meeting, Oklahoma Academy of Science, November 7, 2003, Chickasha, Oklahoma.

58. Jared Crochet, Evan C. Lemley and Wei R. Chen, “Measurement of Thermal Properties of Biological Materials”, 92nd Annual Technical Meeting, Oklahoma Academy of Science, November 7, 2003, Chickasha, Oklahoma.

59. Invited talk Wei R. Chen, “Selective laser-tissue interaction and immunological stimulation in cancer treatment”, Fifth Pacific Rim Conference on Lasers and Electro-Optics (CLEO/PR 2003), December 15-19, 2003, Taipei, Taiwan.

60. Invited talk Wei R. Chen, “New Approaches for Metastatic Cancer Treatment”, Biomedical Engineering Center of the Industrial Technology Research Institute, December 15, 2003, Hsin Chu, Taiwan.

61. Invited Paper Wei R. Chen, Mladen Korbelik, Jinghai Sun, Hong Liu, and Robert E. Nordquist, “Enhancement of glycated chitosan in laser cancer treatment”, Photonics West 2004, January 2004, San Jose, CA.

Wei R. Chen, Ph.D.

Page 60 of 80

62. Vinson G. Liu, Chris A. Bailey, Jared Crochet, and Wei R. Chen, “Simulation of selective photothermal interaction with dye enhancement”, Photonics West 2004, January 2004, San Jose, CA.

63. Qiong Wang, Xinzeng Wu, Wei. R. Chen, John Cheung, and Hong. Liu, “Quantum efficiency of a digital x-ray imaging system for small animal studies”, Photonics West 2004, January 2004, San Jose, CA.

64. Invited talk Wei R. Chen, “Immunological Responses Induced by Treatment of Laser Irradiation and Immunoadjuvant”, 14th International Congress on Photobiology, June 10-15, 2004, Jeju, South Korea.Plenary lecture (Internet) Wei R. Chen, “Anti-tumor immunity induced by laser treatment and immunoadjuvant application”, Saratov Fall Meeting 2004, Workshop on Optical Technologies in Biophysics & Medicine VI, September 2004, Saratov, Russia.

66. Surya Gnyawali and Wei R. Chen, “Simulation of Temperature Distribution in Laser Irradiated Tissue”, 93rd Annual Technical Meeting, Oklahoma Academy of Science, November 5, 2004, Edmond, Oklahoma.

67. Suman Shivakoti and Wei R. Chen, “Measurement of optical properties of tissue by integrating sphere”, 93rd Annual Technical Meeting, Oklahoma Academy of Science, November 5, 2004, Edmond, Oklahoma.

68. Kirill Andrienko and Wei R. Chen, “Optimal Laser-Tissue Treatment Conditions”, 93rd Annual Technical Meeting, Oklahoma Academy of Science, November 5, 2004, Edmond, Oklahoma.

69. Invited talk Wei R. Chen, Mladen Korbelik, Liu Hong, and Robert E. Nordquist, “Photothermal and Photochemical interactions in cancer treatment”, Photonics Asia; November 2004, Beijing, China, Beijing.

70. Invited talk Wei R. Chen, “Laser phototherapy and immunological stimulation in cancer treatment”, Technical Program Committee of Second Asian and Pacific Rim Symposium on Biophotonics (APBP), December, 2004, Taipei, Taiwan.

71. Eric Potter, Fabrice Ouandji, Wei R. Chen and Hong Liu. “Observer-based study of an x-ray imaging system for small animal research”, Photonics West 2005, January 2005, San Jose, CA.

72. Wei R. Chen, Kenneth E. Bartels, Steven Martin, Sang won Jeong, Suman Shivakoti, and Hong Liu, “Laser thermal interaction and glycated chitosan in the treatment of metastatic melanoma in mice”, Photonics West 2005, January 2005, San Jose, CA.

73. Invited talk Wei R. Chen, “Synergistic effects of laser and adjuvant therapies for cancer – Progress in the development of novel cancer treatment methods using combinations of photothermal, photochemical, immunotherapy and chemotherapy”, Photonics West 2005, January 2005, San Jose, CA

74. Wei R. Chen, “In Situ Photo Immunotherapy - A Novel Approach for Treatment of Metastatic Tumors”, Seminar, University of Oklahoma Health Science Center, February 7, 2005.

75. Wei R. Chen, “In Situ Photo Immunotherapy for Malignant Melanoma - Pre-clinical and Clinical Studies”, IDeA Networks of Biomedical Research Excellence (INBRE) Regional Meeting, Kansas City, MO, May 5, 2005.

76. Wei R. Chen, “Laser Photo Immunotherapy for Treatment of Metastatic Tumors – Preclinical and Clinical Studies”, Xingqiao Hospital, Chinese Third Military Medical University, Chongqing, China, June 1, 2005.

77. Wei R. Chen, “Localized Photo Immunotherapy for Cancer Treatment”, Chongqing Medical University, Chongqing, China, June 2, 2005.

Wei R. Chen, Ph.D.

Page 61 of 80

78. Wei R. Chen, “Local Laser Immunotherapy for Treatment of Metastatic Tumors – Preclinical and Clinical Studies, Shandong University Medical School, Jinan, China, June 8, 2005.

79. Wei R. Chen, “Interdisciplinary Synergy in Cancer Research”, Young Teachers’ Salon, South China Normal University, Guangzhou, China, June 10, 2005.

80. Wei R. Chen, “Laser Immunotherapy in Cancer Research”, Graduate School, Tsinghua University, Shenzhen, China, June 13, 2005.

81. Wei R. Chen, “Biomedical Engineering Program at UCO”, Intro to Engineering, Department of Physics and Engineering, University of Central Oklahoma, September 13, 2005.

82. Wei R. Chen, “A Unique Combination Therapy for Metastatic Melanoma”, Department of Dermatology, Roswell Park Cancer Institute, Buffalo, New York, July 28, 2005.

83. Invited talk Wei R. Chen, “Laser photothermal interaction and immunological stimulation for melanoma treatment”, The 4th Photonics and Imaging in Biology and Medicine - PIBM05, Tianjin, China, September 5, 2005.

84. Wei R. Chen, “Biomedical Engineering – A New, Promising Interdisciplinary Field”, Introduction to Engineering Class, Department of Physics and Engineering, University of Central Oklahoma, Edmond, Oklahoma, September 13, 2005.

85. Invited talk Wei R. Chen, “Effects of surgery, immunization, and laser immunotherapy on metastatic tumors in rats”, Saratov Fall Meeting 2005, Workshop on Optical Technologies in Biophysics & Medicine VII, Saratov, Russia, September 2005.

86. Surya C Gnyawali, Yichao Chen, and Wei R Chen, “Monitoring Temperature in Biological tissues using magnetic resonance imaging technique and laser as a heat source”, Sigma Xi Annual Meeting and Student Research Conference, Seattle, Washington, November 3-6, 2005.

87. Surya C. Gnyawali, Yichao Chen, and Wei R. Chen, “3D Thermal Distribution Determination Using Magnetic Resonance Imaging (MRI) During Laser Therapy”, Oklahoma Academy of Science 94th Annual Technical Meeting, Oklahoma City, Oklahoma, November 5, 2005.

88. Yichao Chen, Surya C Gnyawali, and Wei R. Chen, “Temperature Distribution in Biological Tissues using Monte Carlo Simulation”, Oklahoma Academy of Science 94th Annual Technical Meeting, Oklahoma City, Oklahoma, November 5, 2005.

89. Invited talk Wei R. Chen, “Light and immune systems - activation and detection of immunological activities”, Photonics West 2006, San Jose, CA, January 2006.

90. Mark F. Naylor and Wei. R. Chen, “In situ photoimmunotherapy for melanoma – preliminary clinical results”, Photonics West 2006, San Jose, CA, January 2006.

91. Yichao Chen, Surya C. Gnyawali, Kirill. Andrienko, Hong Liu, and Wei R. Chen, “Tissue temperature distribution measurement and laser immunotherapy for cancer treatment”, Photonics West 2006, San Jose, CA, January 2006.

92. Wei R. Chen, “Immunological and photophysical interactions for cancers – INBRE Project Progress Report” External Advisory Committee Meeting, Oklahoma State Regents for Higher Education, Oklahoma City, OK, January 30, 2006.

93. Wei R. Chen, “Biomedical Engineering – A New, Promising Interdisciplinary Field”, Introduction to Engineering Class, Department of Physics and Engineering, University of Central Oklahoma, Edmond, Oklahoma, February 7, 2006.

94. Wei R. Chen, “Laser Immunotherapy”, Langston University, Langston, Oklahoma, February 21, 2006.

95. Invited talk Wei R. Chen, “BIOMEDICAL ENGINEERING – In USA and at University of Central Oklahoma”, Chongqing Medical University, Chongqing, China, June 07, 2006.

96. Invited talk Wei R. Chen, “Current Trend in Cancer Treatment”, Chongqing Medical University, Chongqing, China, June 07, 2006.

Wei R. Chen, Ph.D.

Page 62 of 80

97. Wei R. Chen, “Novel Therapy for Cancer Treatment - Synergism between Engineering and Biological Interactions”, SURE-STEP Lecture, University of Central Oklahoma, Edmond, Oklahoma, July 12-13, 2006.

98. Invited talk Wei R. Chen, “Combination of Laser Phototherapy and Immunotherapy for Malignancies”, Special Session “Laser in Surgery”, the 92nd Annual Clinical Congress of the American College of Surgeons, Chicago, Illinois, October 8-12, 2006.

99. Invited talk Wei R. Chen, “Immunological combination therapy in cancer treatment – preclinical and preliminary clinical results”, the 5th International Conference on Photonics and Imaging in Biology and Medicine (PIBM2006), Wuhan, China, September 1-3, 2006.

100. Invited talk Da Xing, Lei Liu, and Wei R. Chen, “Sub-cell FRET imaging for determination of signaling pathway of cell apoptosis during tumor therapy”, The 5th International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2006), September 1-3, 2006, Wuhan, China.

101. Surya C. Gnyawali, Yichao Chen, Kenneth E. Bartels, Jerry W. Ritchey, James P. Wicksted, Kandace Metcalf, and Wei R. Chen, “Tissue temperature distribution during Laser-Immunotherapy for metastatic cancers”, Oklahoma Academy of Science 95th Annual Technical Meeting, Rogers State University, Claremore, Oklahoma, November 3, 2006.

102. Gaurav Kumar, Yichao Chen, and Wei R. Chen, “Tissue temperature measurement using MRI”, Oklahoma Academy of Science 95th Annual Technical Meeting, Rogers State University, Claremore, Oklahoma, November 3, 2006.

103. Abdul Mohamed, Jennifer Ellis, and Wei R. Chen, “Effect of laser immunotherapy in cancer treatment using Immunological assays”, Oklahoma Academy of Science 95th Annual Technical Meeting, Rogers State University, Claremore, Oklahoma, November 3, 2006.

104. Yuhua Li, Wei R. Chen, and Hong Liu, “The Characterization of Computed Radiography X-ray Phase Contrast Imaging System”, Conference of Complex Dynamics and Fluctuations in Biomedical Photonics IV, Photonics West, 2007, San Jose, CA, January, 2007.

105. Mark F. Naylor, Kent Teague, and Wei R. Chen, “In Situ Photoimunotherapy (ISPI) for Advanced Cutaneous Melanoma”, Conference of Biophotonics and Immune Responses II, Photonics West, 2007, San Jose, CA, January, 2007.

106. Surya C Gnyawali,Yichao Chen, K.E. Bartels, J. P. Wicksted, and Wei R Chen, “Mapping Surface Temperature on Biological Tissues by Infrared Thermography (IRT)”, Conference of Biophotonics and Immune Responses II, Photonics West, 2007, San Jose, CA, January, 2007.

107. Invited talk Wei R. Chen, Kenneth E. Bartels, Jerry W. Ritchey, and Steven D. Martin, “Cellular Immunological Effect of Laser Irradiation and Immunoadjuvant Application”, Conference of Biophotonics and Immune Responses II, Photonics West, 2007, San Jose, CA, January, 2007.

108. Yichao Chen, Surya C. Gnyawali, Hong Liu, and Wei R. Chen, “Tissue temperature distribution measurement by MRI and laser immunotherapy for cancer treatment”, Conference of Biophotonics and Immune Responses II, Photonics West, 2007, San Jose, CA, January, 2007.

109. Wei R. Chen, Radio Interview on Laser Immunotherapy Treatment of Metastatic Cancer, Oklahoma Innovation Program, Oklahoma City, March 5, 2007.

110. Invited talk Wei R. Chen, “Combination of phototherapy and immunotherapy for cancer – A Novel Approach for Metastatic Tumors”, Fujian Normal University, Fuzhou, Fujian, China, March 10, 2007.

111. Invited Lecture Wei R. Chen, “Principles of Biomedical Engineering – Electricity in Cells - Nerves & Muscles”, Chongqing Medical University, Chongqing, China, June 03, 2007.

Wei R. Chen, Ph.D.

Page 63 of 80

112. Invited talk Wei R. Chen, “Active Immune Stimulation and Local Phototherapy for Treatment of Metastatic Cancer”, Chongqing Medical University, Chongqing, China, June 04, 2007.


114. Wei R. Chen, “MRI-Guided Photoimmunotherapy – INBRE Project Progress Report” External Advisory Committee Meeting, Oklahoma State Regents for Higher Education, Oklahoma City, OK, August 23, 2007.

115. Invited talk Wei R. Chen, “Local phototherapy and immunotherapy for treatment of metastatic tumors”, 12th Congress of the European Society for Photobiology, Bath, United Kingdom, September 6, 2007.

116. Colloquium Speaker Wei R. Chen, “A Novel Therapy for Metastatic Tumors Using Photothermal and Immunological Interactions”, Department of Physics, University of Oklahoma, Norman, Oklahoma, October 04, 2007.

117. Invited talk Wei R. Chen, “Recent Development in Treatment of Metastatic Tumors”’ International Conference Photonics Pacific Rim - Photonics and Imaging in Biology and Medicine (PIBM2007), Wuhan, China, November 05, 2007.

118. Invited talk Wei R. Chen, “Outcomes and mechanisms of laser immunotherapy in the treatment of melanoma”’ SPIE International Conference of Optics in Health Care and Biomedical Optics, Photonics Asia, Beijing, China, November 13, 2007.

119. Lei Liu, Da Xing, and Wei R. Chen, “Calpain mediates AIF-regulated caspase-independent pathway in cisplatin-induced apoptosis”’ SPIE International Conference of Optics in Health Care and Biomedical Optics, Photonics Asia, Beijing, China, November 15, 2007.

120. Invited talk Wei R. Chen, “Laser Immunotherapy – History, pre-clinical, clinical and immunological studies”, Laser Therapy Division, Beijing 301 Hospital, Beijing, China, November 14, 2007.

121. Lei Liu, Da Xing, and Wei R. Chen, “Calpain mediates AIF-regulated caspase-independent pathway in cisplatin-induced apoptosis”’ submitted to SPIE Proceedings, Photonics Asia, Beijing, China, November 15, 2007.

122. Invited Talk, Mark F. Naylor, Kent Teague, and Wei R. Chen, “Clinical results in a phase I melanoma trial using in situ photoimmunotherapy”, Conference of Biophotonics and Immune Responses III, Photonics West, 2008, San Jose, CA, January 21, 2008.

123. Invited Talk, Wei R. Chen, Kent Teague, and Mark F. Naylor, “Immunological responses induced by the combination of phototherapy and immunotherapy in the treatment of metastatic melanoma”, Conference of Biophotonics and Immune Responses III, Photonics West, 2008, San Jose, CA, January 21, 2008.

124. Feifan Zhou, Da Xing, and Wei R. Chen, “PDT-apoptotic tumor cells induce macrophage immune response”, Conference of Biophotonics and Immune Responses III, Photonics West, 2008, San Jose, CA, January 21, 2008.

125. Lei Liu, Qingling Wan, Da Xing, Feifan Zhou, and Wei R. Chen, “Spatial and temporal changes in Bax subcellular localization during NPe6-PDT-induced apoptosis”, Conference of Biophotonics and Immune Responses III, Photonics West, 2008, San Jose, CA, January 21, 2008.

126. Yichao Chen, Gurav Kumar, Jennifer Ellis, Feng Wu, Hong Liu, Rheal A. Towner, and Wei R. Chen, “The correlation study of temperature distribution with the immunology response under laser radiation”, Conference of Biophotonics and Immune Responses III, Photonics West, 2008, San Jose, CA, January 21, 2008.

Wei R. Chen, Ph.D.

Page 64 of 80

127. Xingwei Wang, Bin Zheng, Shibo Li, John J. Mulvihill, Wei R. Chen, Hong Liu, “Development of an integrated computerized scheme for metaphase chromosome image analysis: a robustness experiment”, Conference of Complex Dynamics and Fluctuations in Biomedical Photonics V, Photonics West, 2008, San Jose, CA, January 19, 2008.

128. Yichao Chen, Gaurav Kumar, Jennifer Ellis, Feng Wu, Hong Liu, Rheal A. Towner, and Wei R. Chen, “Gel phantom in selective laser phototherapy”, Conference of Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue, Photonics West, 2008, San Jose, CA, January 19, 2008.

129. Wei R. Chen, “Recent Development in Treatment of Metastatic Tumors”, Presentation to Biomedical Engineering Laboratory, University of Central Oklahoma, Edmond, Oklahoma, February 7, 2008.

130. Wei R. Chen, “BIOMEDICAL ENGINEERING – A New, Promising Interdisciplinary Field”, Presentation to Summer Academy, Department of Engineering and Physics, University of Central Oklahoma, Edmond, Oklahoma, June 13, 2008.


132. Short Course Wei R. Chen, “Photoimmunological Effects in Cancer Treatment”, Saratov Fall Meeting 2008, Saratov, Russia, September 23, 2008.

133. Plenary lecture Wei R. Chen, “Enhancement of photothermal interactions in treatment of tumors using laser and nanotubes”, Saratov Fall Meeting 2008, Workshop on Optical Technologies in Biophysics & Medicine X, Saratov, Russia, September 24, 2008.

134. Invited Talk Wei R. Chen, “Challenges in Phototherapy for Cancer”, Saratov Fall Meeting 2008, Presentation to Saratov High School Math-Physics Students, Saratov, Russia, September 24, 2008.

135. Invited Talk Wei R. Chen, “Biomedical engineering approach for cancer treatment”, Presentation to the 2008 Arkansas-Oklahoma-Kansas (AOK) Association of American Physics Teachers (AAPT) Meeting, Rose State College, Midwest City, Oklahoma, November 1, 2008.

136. Invited Talk Wei R. Chen, Mikaela Chen, and James Chen “Introduction to and Appreciation of Chinese Musical Instruments”, Lecture and Presentation to the Passport to China Program, University of Central Oklahoma, Edmond, Oklahoma, November 1, 2008.

137. Wei R. Chen, Feifan Zhou, and Da Xing, “Laser-nanotube photothermal therapy for cancer treatment”, 6th Asian Biophysics Association (ABA) Symposium, Hong Kong, China, January 11-14, 2009.

138. Xingwei Wang, Bin Zheng, Shibo Li, Roy Zhang, John Mulvihill, Wei R. Chen, and Hong Liu, “Automated segmentation and analysis of fluorescent in situ hybridization (FISH) signals in interphase nuclei of pap-smear specimens”, Conference of Dynamics and Fluctuations in Biomedical Photonics VI, Photonics West, 2009, San Jose, CA, January 24, 2009.

139. Da Zhang, Xizeng Wu, Molly Wong, John Rong, Wei R. Chen, and Hong Liu, “Error analysis in the measurement of x-ray photon fluence”, Conference of Dynamics and Fluctuations in Biomedical Photonics VI, Photonics West, 2009, San Jose, CA, January 24, 2009.

140. Mark F. Naylor, Robert Nordquist, Henry Le, Chet Joshi, Hong Liu, and Wei R. Chen, “Treatment of persistent stage III melanoma patients using a combination of imiquimod and laser irradiation”, Conference of Biophotonics and Immune Responses IV, Photonics West, 2009, San Jose, CA, January 26, 2009.

141. Robert Nordquist, Wei R. Chen, Kelvin Le, Halie Ferguson, John Nordquist, and Hong Liu, “The roles of treated tumor cells in immunological responses following laser immunotherapy”,

Wei R. Chen, Ph.D.

Page 65 of 80

Conference of Biophotonics and Immune Responses IV, Photonics West, 2009, San Jose, CA, January 26, 2009.

142. Wei R. Chen, Akhee Sarker, Hong Liu, and Robert Nordquist, “Effects of immunostimulant in phototherapy for cancer treatment”, Conference of Biophotonics and Immune Responses IV, Photonics West, 2009, San Jose, CA, January 26, 2009.Feifan Zhou, Xing Da, and Wei R. Chen, “HSP70 inhibit Bax translocation during Photofrin-PDT apoptosis”, Conference of Biophotonics and Immune Responses IV, Photonics West, 2009, San Jose, CA, January 26, 2009.Wei R. Chen, “Recent Development in Treatment of Metastatic Tumors”, Presentation to Introduction to Biomedical Engineering, University of Central Oklahoma, Edmond, OK, April 1, 2009.Wei R. Chen, Guest lecture at Research Day, Florida Golf Coast University, Ft. Meyers, FL April 24, 2009.Wei R. Chen, Guest lecture “Laser Immunotherapy – A Novel Approach for Metastatic Tumors”, Edmond Kiwanis Club, Edmond, OK, April 29, 2009.

148. Wei R. Chen, “Novel Therapy for Cancer Treatment - Synergism between Engineering and Biological Interactions”, STEP Summer Bridge Lecture, University of Central Oklahoma, Edmond, Oklahoma, July 20, 2009.

149. Wei R. Chen, “Enhancement of photothermal interactions in treatment of tumors using laser and nanotubes”, 2009 International Conference on Optical Instrumentation and Technology, Shanghai, China, October 19-22, 2009.Wei R. Chen, “Biomedical Engineering – A New, Promising Interdisciplinary Field, and Laser Immunotherapy – A New, Promising Interdisciplinary Method”, Oklahoma ABC Chinese School, Edmond, OK, December 6, 2009.

151. Vivian, A. Chen, Henry, Le, Xiaosong, Li, Roman F. Wolf, Halie Ferguson, Akhee Sarkar, Hong Liu, Robert E. Nordquist, and Wei R. Chen, “Effect of laser immunotherapy and surgery on the treatment of mouse mammary tumors”, Conference of Biophotonics and Immune Responses V, Photonics West, 2010, San Francisco, CA, January 25, 2010.

152. Xiaosong Li, Mark F. Naylor, Robert E. Nordquist, T. Kent Teague, C. Anthony Howard, Cynthia Murray, and Wei R. Chen, “Preliminary results of a phase I/II clinical trial using in situ photoimmunotherapy combined with imiquimod for metastatic melanoma patients”, Conference of Biophotonics and Immune Responses V, Photonics West, 2010, San Francisco, CA, January 25, 2010.

153. Tomas Hode, Maria C. Guerra, Gabriela L. Ferrel, John A. Lunn, Orn Adelsteinsson, Robert E. Nordquist, and Wei R. Chen, “Laser immunotherapy: initial results from a human breast cancer pilot trial”, Conference of Biophotonics and Immune Responses V, Photonics West, 2010, San Francisco, CA, January 25, 2010.

154. Christine M. N. Yow, Chi M. Cheung, and Wei R. Chen, Zheng Huang, “Preliminary study of antibacterial effect of glycated chitosan”, Conference of Biophotonics and Immune Responses V, Photonics West, 2010, San Francisco, CA, January 25, 2010. Wei R. Chen, “Laser-Assisted Immunotherapy”, Piura Hospital Administrator Meeting, Lima, Peru, March 16, 2010.

156. Interactive Lecture, Wei R. Chen, Beverly Endicott, Charles Hughes, and Charlotte Simmons, “Developing Undergraduate Research from Within: Transforming Faculty into Advocates for Student-Centered Research”, Council on Undergraduate Research Conference, Ogden, Utah, June 19-22, 2010.Wei R. Chen, “Novel Therapy for Cancer Treatment - Synergism between Engineering and Biological Interactions”, STEP Summer Bridge Lecture, University of Central Oklahoma, Edmond, Oklahoma, July 13, 2010.Wei R. Chen, “Novel Therapy for Cancer Treatment - Synergism between Engineering and Biological Interactions”, STEP Fall Bridge Lecture, University of Central Oklahoma, Edmond, Oklahoma, July 25, 2010.

159. Invited talk Wei R. Chen,, “ABET Accreditation in the United States”, The Sino-American Presidents and Deans Forum – Quality Assurance and Global Strategy in Higher Education, Shanghai, China, August, 3, 2010.

Wei R. Chen, Ph.D.

Page 66 of 80

160. Invited talk Wei R. Chen, “Treatment of metastatic tumors using laser immunotherapy: Pre-clinical and clinical results”’ International Conference - Photonics and Imaging in Biology and Medicine (PIBM2010), Wuhan, China, November 02, 2010.

161. Xiaosong Li, Feifan Zhou, Robert E. Nordquist, Hong Liu, Tomas L. M. Hode, and Wei R. Chen, “Mechanism study of tumor-specific immune responses induced by laser immunotherapy: in situ autologous whole-cells cancer vaccine”, Conference of Biophotonics and Immune Responses VI, Photonics West, 2011, San Francisco, CA, January 24, 2011.

162. Robert E. Nordquist, Shelly Bishop, Xiaosong Li, Halie Ferguson, Melville B. Vaughan, and Wei R. Chen, “Immunohistochemical analysis of immune response in breast cancer and melanoma patients after laser immunotherapy”, Conference of Biophotonics and Immune Responses VI, Photonics West, 2011, San Francisco, CA, January 24, 2011.

163. Sheng Song, Feifan Zhou, Da Xing, and Wei R. Chen, “Molecular mechanism of PDT-induced apoptotic cells stimulation NO production in macrophages”, Conference of Biophotonics and Immune Responses VI, Photonics West, 2011, San Francisco, CA, January 24, 2011.

164. Invited Talk Tomas L. M. Hode, Orn Adalsteinsson, Gabriela L. Ferrel, John A. Lunn, Maria Guerra, Xiaosong Li, Robert E. Nordquist, and Wei R. Chen, “Laser immunotherapy for the treatment of human breast cancer: 1-year follow-up results”, Conference of Biophotonics and Immune Responses VI, Photonics West, 2011, San Francisco, CA, January 24, 2011.

165. Invited Talk Wei R. Chen, Daniel Figueroa, Tomas L. M. Hode, Robert E. Nordquist, onny Walla, Roman F. Wolf, Hong Liu, and Xiaosong Li, “Interstitial laser immunotherapy in the treatment of DMBA-4 metastatic tumors in rats”, Conference of Biophotonics and Immune Responses VI, Photonics West, 2011, San Francisco, CA, January 24, 2011.

166. Wei R. Chen, Daniel Figueroa, Kelvin Le, Xiaosong Li, Jonny Walla, Roman F. Wolf, Hong Liu, Robert E. Nordquist, and Tomas L. M. Hode, “Thermal effect induced by interstitial irradiation of near-infrared laser with cylindrical diffuser”, Conference of Biophotonics and Immune Responses VI, Photonics West, 2011, San Francisco, CA, January 24, 2011.

167. Yuchen Qiu, Xiaodong Chen, Yuhua Li, Zheng Li, Bin Zheng, Shibo Li, Wei R. Chen, and Hong Liu, “The impact of the depth-of-field to image quality in high-magnification microscopic scanning”, Conference of Biophotonics and Immune Responses VI, Photonics West, 2011, San Francisco, CA, January 24, 2011.

168. Feifan Zhou, Da Xing, and Wei R. Chen, “Direct imaging the subcellular localization of single-walled carbon nanotubes”, Conference of Biophotonics and Immune Responses VI, Photonics West, 2011, San Francisco, CA, January 24, 2011.

169. Wei R. Chen, “Laser Immunotherapy – A New, Promising Interdisciplinary Method”, Medical Imaging Class, University of Central Oklahoma, Edmond, Oklahoma, February 14, 2011.

170. Wei R. Chen, “Laser Immunotherapy – A novel approach for the treatment of late-stage, metastatic breast cancer”, Women’s Cancer Program Research Retreat, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, February 25, 2011.

171. Wei R. Chen, “Laser Immunotherapy for the Treatment of Late-Stage, Metastatic Breast Cancer”, Breast Cancer Research Planning Meeting, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, May 16, 2011.

172. Wei R. Chen, Award Acceptance Speech, 2011 Oklahoma Medal for Excellence in Teaching Annual Academic Award Banquet, Norman, Oklahoma, May 21, 2011.

173. Wei R. Chen, “A Novel Laser Immunotherapy for Treatment of Metastatic Cancers: Pre-clinical and Clinical Studies”, Shenzhen University, Shenzhen, China, June 10, 211.

174. Wei R. Chen, “Laser Immunotherapy for Treatment of Metastatic Cancer Patients”, 301 Hospital, Beijing, China, June 17, 2011.

Wei R. Chen, Ph.D.

Page 67 of 80

175. Wei R. Chen, “Laser Immunotherapy – A Novel Treatment Modality for Metastatic Cancers: Its Past, Present and Future”, Fujian Normal University, Fuzhou, China, August 19, 2011.

176. Wei R. Chen, “Co-Existence with Cancer: A Nightmare, A Fantasy, or A Destiny of Human Race?”, China Pharmaceutical University, Nanjing, China, August 31, 2011.

177. Wei R. Chen, “Fulbright Lecturing/Research Award for Taiwan”, Presentation at the Fulbright Grantee Orientation, Taipei, Taiwan, September 9, 2011.

178. Wei R. Chen, “In situ autologous whole-cells cancer vaccination induced by photothermal interaction and immunological stimulation”, The 10th International Conference on Photonics and Imaging in Biology and Medicine, Wuhan, China, November 2-5, 2011.

179. Wei R. Chen, “Innovations in Cancer Treatment”, Department of Radiological Sciences, National Yang Ming University, Taipei, Taiwan, November 18, 2011.

180. Wei R. Chen, “Combination of Laser Irradiation and Immunological Stimulation for Cancer Treatment”, International Photonics Conference (IPC 2011), Tainan City, Taiwan, December 8-10, 2011.

181. Wei R. Chen, “Laser-Assisted Immunotherapy–An in situ Autologous Cancer Vaccine (inCVAX) for Metastatic Cancers”, LAMMP/BME Seminar Series, Beckman Laser Institute, University of California at Irvine, Irvine, California, January 19, 2012.

182. Mark F. Naylor, Henry Le, Hong Liu, Robert E. Nordquist, Tomas Hode, and Wei R. Chen, “Long-term effects of laser-imiquimod combination in the treatment of late-stage melanoma patients”, Conference of Biophotonics and Immune Responses VII, Photonics West, 2012, San Francisco, CA, January 23, 2012.

183. Tomas Hode, Orn Adalsteinsson, Gabriela Ferrel, John Lunn, Maria Guerra, Xiaosong Li, Robert E. Nordquist, and Wei R. Chen, “Laser immunotherapy for the treatment of human breast cancer: 2-year follow-up results”, Conference of Biophotonics and Immune Responses VII, Photonics West, 2012, San Francisco, CA, January 23, 2012.

184. Wei R. Chen, Chet Joshi, Daniel Figueroa, Kelvin Le, Hong Liu, Robert E. Nordquist, and Tomas Hode, “Interstitial laser irradiation for the treatment of metastatic mammary tumors in combination of intratumoral injection of immunoadjuvant”, Conference of Biophotonics and Immune Responses VII, Photonics West, 2012, San Francisco, CA, January 23, 2012.

185. Jessica Goddard, Jessnie Jose, Daniel Figueroa, Kelvin Le, Hong Liu, Robert E. Nordquist, Tomas Hode, and Wei R. Chen, “Magnetic resonance thermometry using proton resonance frequency method to monitor photothermal effects of interstitial laser irradiation”, Conference of Biophotonics and Immune Responses VII, Photonics West, 2012, San Francisco, CA, January 23, 2012.

186. Yuchen Qiu, Xiaodong Chen, Z. Li, Wei R. Chen, Bin Zheng, Sibo. Li, and Hong Liu, “An Automatic Scanning Method for High Throughput Microscopic System to Facilitate Medical Genetic Diagnosis: An Initial Study”, Conference of Biophotonics and Immune Responses VII, Photonics West, 2012, San Francisco, CA, January 23, 2012.

187. Mel B. Vaughan, Chelsea Spencer, Jessica Goddard, and Wei R. Chen, “Effect of near-infrared lasers on myofibroblast differentiation and contraction”, Conference of Biophotonics and Immune Responses VII, Photonics West, 2012, San Francisco, CA, January 23, 2012.

188. Okhil K. Nag and Wei R. Chen, “Cellular internalization of a membrane binding two-photon probe by forming a nanostructure composed of anionic diblock copolymer and cationic surfactant”, Conference of Biophotonics and Immune Responses VII, Photonics West, 2012, San Francisco, CA, January 23, 2012.

189. Wei R. Chen, “Laser Immunotherapy for Metastatic Cancers”, Molecular Imaging Center, National Taiwan University, Taipei, Taiwan, February 09, 2012.

Wei R. Chen, Ph.D.

Page 68 of 80

190. Wei R. Chen, “Laser Immunotherapy for Metastatic Cancers”, Chung Yuan Christian University, Chung Li, Taiwan, April 04, 2012.

191. Wei R. Chen, “Laser immunotherapy: a Biomedical engineering approach to target the root cause of cancer”, National Cheng Kung University, Tainan City, Taiwan, April, 09, 2012.

192. Wei R. Chen, “Laser immunotherapy for metastatic cancers: Photons, molecules and immune cells”, International Conference on “Cosmos, Cancer, Criticality and Chromoplasmology”, Seattle, Washington, May 06, 2012.

193. Wei R. Chen, “Targeted therapy + immunotherapy: a Biomedical engineering approach for the treatment of metastatic cancers”, Hungkuang University, Taichung, Taiwan, May 23, 2012.

194. Wei R. Chen, “Laser photothermal targeted therapy + immunotherapy: a novel approach for the treatment of metastatic cancers”, Institute of Biopharmaceutical Sciences, National Yang Ming University, June 25, 2012.

195. Wei R. Chen, “Laser targeted therapy + immunotherapy for treatment of metastatic cancers”, 2012 Oklahoma STEP program, Summer Bridge, University of Central Oklahoma, Edmond, Oklahoma, July 12, 2012.

196. Wei R. Chen, “Cancer Treatment: A History of Innovations”, Fujian Normal University, Fuzhou, Fujian, China, August 06, 2012.

197. Wei R. Chen, “Cancer Treatment: History, Challenges, Innovations, and Laser Immunotherapy”, UCO Pre-Med Club Meeting, Edmond, Oklahoma, October 02, 2012.

198. Wei R. Chen, “Sabbatical Leave + Fulbright Scholarship = An Exotic Academic and Cultural Adventure in a Foreign Country”, Sigma Xi UCO Chapter Lecture, Edmond, Oklahoma, October 18, 2012.

199. Wei R. Chen, “Interstitial laser irradiation in photoimmunotherapy”, Optics in Health Care and Biomedical Optics V, Photonics Asia 2012, Beijing, China, November 05, 2012.Wei R. Chen, “Laser Phototherapy + Immunotherapy –Targeting the Immunological Roots of Cancer”, Qian Fe Shan Hospital, Jinan, Shandong, China, November 08, 2012.

201. Mark F. Naylor, Robert E. Nordquist, John A. Lunn, Orn Adalsteinsson, Tomas Hode, Hong Liu, and Wei R. Chen, “In situ photoimmunotherapy for melanoma”, Conference of Biophotonics and Immune Responses VIII, Photonics West, 2013, San Francisco, CA, February 4, 2013.

202. Tomas Hode, Orn Adalstensson, Gabriela L. Ferrel, John A. Lunn, Xiaosong Li, Robert E. Nordquist, and Wei R. Chen, “Survival of late-stage breast cancer patients after the treatment of laser immunotherapy”, Conference of Biophotonics and Immune Responses VIII, Photonics West, 2013, San Francisco, CA, February 4, 2013.

203. Cody Bahavar, Jessica D. Goddard, Jessnie Jose, Roman F. Wolf, Eric Howard, Hong Liu, Tomas Hode, Immunophotonics, Robert E. Nordquist, and Wei R. Chen, “Interstitial laser immunotherapy: a preliminary in vivo study”, Conference of Biophotonics and Immune Responses VIII, Photonics West, 2013, San Francisco, CA, February 4, 2013.

204. Melville B. Vaughan, Jessica D. Goddard, Jessnie Jose, Chelsea Spencer, Joseph R. Acquaviva, and Wei R. Chen, “Biological effects of near-infrared lasers on myofibroblast cellular differentiation and contraction”, Conference of Biophotonics and Immune Responses VIII, Photonics West, 2013, San Francisco, CA, February 4, 2013.

205. Zhifang Li, Hui Li, and Wei R. Chen, “Monitoring tissue temperature distribution for photothermal cancer therapy based on photoacoustic imaging: a simulated analysis”, Conference of Biophotonics and Immune Responses VIII, Photonics West, 2013, San Francisco, CA, February 4, 2013.

206. Sisi Cui, Haiyan Chen, Zhiyu Qian, Wei R. Chen, and Yueqing Gu, “Folate receptor-mediated tumor-targeted upconversion nanocomplex for photodynamic therapy triggered by

Wei R. Chen, Ph.D.

Page 69 of 80

nearinfrared”, Conference of Biophotonics and Immune Responses VIII, Photonics West, 2013, San Francisco, CA, February 4, 2013.

207. Wei R. Chen, Xiaosong Li, Okhil K. Nag, Jessica D. Goddard, Joseph Acquaviva, Yongqiang Tan, Tomas Hode, and Hong Liu, “Photothermal effects of immunologically modified carbon nanotubes”, Conference of Biophotonics and Immune Responses VIII, Photonics West, 2013, San Francisco, CA, February 4, 2013.

208. Muhammad U. Ghani, Di Wu, Minhua Kang, Yuhua Li, Wei R. Chen, Xizeng Wu, and Hong Liu, “Quantitative analysis of contrast to noise ratio using a phase contrast x-ray imaging prototype”, Conference of Biophotonics and Immune Responses VIII, Photonics West, 2013, San Francisco, CA, February 4, 2013.

209. Yuchen Qiu, Yuhua Li, Bin Zheng, Shibo Li, Wei R. Chen, and Hong Liu, “The impact of the motion blur on pathological chromosome image quality: a preliminary study”, Conference of Biophotonics and Immune Responses VIII, Photonics West, 2013, San Francisco, CA, February 4, 2013.

210. Di Wu, Hui Miao, Yuhua Li, Wei R. Chen, Xizeng Wu, and Hong Liu, “An intrinsic method in characterizing the potential and imaging quality of a phase-contrast tomosynthesis prototype by using phantoms”, Conference of Biophotonics and Immune Responses VIII, Photonics West, 2013, San Francisco, CA, February 4, 2013.

211. Wei R. Chen, “Cancer Research @ UCO – Search for a cure for late-stage, metastatic cancers”, UCO Alumni Board Meeting, UCO, Edmond, Oklahoma, February 22, 2013.

212. Wei R. Chen, “Laser Immunotherapy: Cancer Research @ UCO – A Search for a cure for late-stage, metastatic cancers”, Presentation to Introduction to Biomedical Engineering, University of Central Oklahoma, Edmond, OK, March 28, 2013.

213. Wei R. Chen, “LASER IMMUNOTHERAPY FOR LATE-STAGE, METASTATIC CANCERS”, SCC Annual Research Symposium, University of Oklahoma Stephenson Cancer Center, Oklahoma City, Oklahoma, March 29, 2013.

214. Wei R. Chen, “Cancer Research @ UCO – A Search for a cure for late-stage, metastatic cancers”, Presentation to Biomedical Imaging Class, University of Central Oklahoma, Edmond, OK, April 8, 2013.

215. Invited talk Wei R. Chen, “Induction and detection of photoimmunological responses in cancer treatment”, The 11th International Conference on Photonics and Imaging in Biology and Medicine, Wuhan, China, May 26-29, 2013.

216. Invited talk Wei R. Chen, “In situ photoimmunotherapy for treatment of patients with late-stage, metastatic melanoma”, The 3rd International Shanghai PDT Forum, Shanghai, China, June 1, 2013.

217. Invited talk Wei R. Chen, “Selective laser-tissue photothermal interactions in cancer treatment”, Physics Department, University of Otago, Dunedin, New Zealand, June 24, 2013.Invited talk Wei R. Chen, “Harnessing immune activities for cancer treatment using phototherapy and immunotherapy”, Public Lecture, University of Otago Medical School, Dunedin, New Zealand, June 25, 2013.

219. Invited talk Wei R. Chen, “inCVAX – A new treatment modality for metastatic cancers”, Institute of Medical Physics, University of Sydney Sydney, Australia, June 27, 2013.

220. Wei R. Chen, “Cancer Treatment – Past, Present, and Future”, 2013 Oklahoma STEP program, Summer Bridge, University of Central Oklahoma, Edmond, Oklahoma, July 02, 2013.

221. Invited talk Wei R. Chen, “Harnessing host immune reactions for cancer treatment using laser immunotherapy”, Seminar at Shanghai Skin Disease Hospital, Shanghai, China, July 30, 2013.

222. Invited talk Wei R. Chen, “Laser Immunotherapy for Cancer Treatment”, Asia Communications and Photonics Conference (ACP2013), Beijing, China, November 15, 2013.

Wei R. Chen, Ph.D.

Page 70 of 80

223. Cody Bahavar, Aamr Hasanjee, Ethan Wood and Wei R. Chen, “LASER IMMUNOTHERAPY FOR TREATMENT OF METASTATIC TUMORS”, 102nd Annual Technical Meeting, Oklahoma Academy of Science, November 08, 2013, Lawton, Oklahoma.

224. Pinar Avci, Gaurav K. Gupta, Masayoshi Kawakubo, Ji Wang, Wei R. Chen, Tomas Hode, Mei X. Wu, and Michael R. Hamblin, "Glycated chitosan as a vaccine adjuvant", Conference of Biophotonics and Immune Responses IX, Photonics West, 2014, San Francisco, CA, February 3, 2014.

225. Invited talk Wei R. Chen, Mark F. Naylor, and Robert E. Nordquist, "In situ photoimmunotherapy and t-cell simulations in melanoma treatment", Conference of Biophotonics and Immune Responses IX, Photonics West, 2014, San Francisco, CA, February 3, 2014.

226. Joseph T. Acquaviva III, Wei R. Chen, Melville B. Vaughan, Hong Liu, and Eric Howard, "Effects of laser immunotherapy on tumor microenvironment", Conference of Biophotonics and Immune Responses IX, Photonics West, 2014, San Francisco, CA, February 3, 2014.

227. Cody F. Bahavar, Wei R. Chen, Tomas Hode, Robert E. Nordquist, Hong Liu, "Effects of cyclophosphamide on laser immunotherapy for the treatment of metastatic cancer", Conference of Biophotonics and Immune Responses IX, Photonics West, 2014, San Francisco, CA, February 3, 2014.

228. Sean M. Laverty, Bryan Dawkins, and Wei R. Chen, "Laser immunotherapy and the tumor-immune system interaction: a mathematical model and analysis", Conference of Biophotonics and Immune Responses IX, Photonics West, 2014, San Francisco, CA, February 3, 2014.

229. Di Wu, Aimin Yan, Yuhua Li, Molly Wong, Wei R. Chen, Xizeng Wu, and Hong Liu, "Characterization study of an high-energy in-line phase contrast tomosynthesis prototype", Conference of Biophotonics and Immune Responses IX, Photonics West, 2014, San Francisco, CA, February 3, 2014.

230. Liqiang Ren, Di Wu, Yuhua Li, Wei R. Chen, and Hong Liu, "Comparison of background removal methods in X-ray fluorescence analysis using gold nanoparticles", Conference of Biophotonics and Immune Responses IX, Photonics West, 2014, San Francisco, CA, February 3, 2014.

231. Wei R. Chen, Robert E. Nordquist, Feifan Zhou, Hong Liu, and Tomas Hode, "Anti-tumor immunological effects induced by laser-nanotechnology", Conference of Biophotonics and Immune Responses IX, Photonics West, 2014, San Francisco, CA, February 3, 2014.

232. Wei R. Chen, “Laser Immunotherapy: Cancer Research @ UCO – A Search for a cure for late-stage, metastatic cancers”, Presentation to Introduction to Biomedical Engineering, University of Central Oklahoma, Edmond, OK, February 13, 2014.

233. Wei R. Chen, “Magnetic Resonance Thermometry Using the Proton Resonance Frequency Method to Monitor Photothermal Effects of Interstitial Laser Irradiation”, Presentation to Bioinstrumentation Class, University of Central Oklahoma, Edmond, OK, February 17, 2014.

234. John F. Barthell, Charlotte K. Simmons, Gregory M. Wilson, Beverly K. Endicott, Evan A. Lemley, and Wei R. Chen, “Strategies for Sustaining STEP Activities: Internal resources and external funding Faculty development and student support”, Panel Discussion, 2014 NSF STEP Grantee Meeting, Washington, D.C., March 6, 2014.

235. Wei R. Chen, "Targeting tumor tissue using photothermal interactions", School of Physics, National University Ireland, Galway, Ireland, May 22, 2014.

236. Wei R. Chen, "Enlisting our own immune systems to fight against cancer", National University Ireland, Galway, Ireland, May 23, 2014.

Wei R. Chen, Ph.D.

Page 71 of 80

237. Invited Talk Wei R. Chen, "In Situ Cancer Vaccine Induced by Photoimmunotherapy", The International Congress on Photodynamic Applications (ICPA) 2014, Dundee, Scotland, May 26, 2014.

238. Wei R. Chen, "Determination of temperature distribution in targeted tissue during laser irradiation", Shanghai Skin Disease Hospital, Shanghai, China, June 14, 2014.

239. Invited talk Wei R. Chen, “Nanotechnology-based immunophotonics in cancer treatment” International Conference - Photonics and Imaging in Biology and Medicine (PIBM2014), Wuhan, China, June 16, 2014.

240. Wei R. Chen, "Determination of temperature distribution in target tissue during laser irradiation", College of Photonic and Electric Engineering, Fujian Normal University, Fuzhou, China, June 19, 2014.


242. Wei R. Chen, "Clinical Cancer Immunotherapy - Past, Current, and Future", Huazhong University of Science and Technology, Wuhan, China, September 17, 2014.

243. Wei R. Chen, "Laser Immunotherapy - Past Development, Current Status, and Future Outlook", The 3rd International Tumor PDT Summit Forum, Xiamen, China, September 18, 2014.

244. Invited talk Tomas Hode, Lu Alleruzzo, Joseph Raker, Samuel Lam, Peter Jenkins, Robert E. Nordquist, and Wei R. Chen, "Development of a novel cancer treatment from bench top to bedside", Conference of Biophotonics and Immune Responses X, Photonics West, 2015, San Francisco, CA, February 9, 2015.

245. Invited talk Mark F. Naylor, Gabriela L. Ferrel, Xiaosong Li, Tomas Hode, Robert E. Nordquist, and Wei R. Chen, "Clinical experience with laser immunotherapy (LIT)", Conference of Biophotonics and Immune Responses X, Photonics West, 2015, San Francisco, CA, February 9, 2015.

246. Invited talk Mladen Korbelik, Judit Banath, and Wei R. Chen, "Activity of glycated chitosan and other adjuvants to PDT vaccines", Conference of Biophotonics and Immune Responses X, Photonics West, 2015, San Francisco, CA, February 9, 2015.

247. Invited talk Jie Ji, Xiuli Wang, Zhixia Fan, Wei R. Chen, Haiyan Zhang, and Hongwei, Wang, "ALA-PDT mediated DC vaccine for skin squamous cell carcinoma", Conference of Biophotonics and Immune Responses X, Photonics West, 2015, San Francisco, CA, February 9, 2015.

248. Mark F. Naylor, Tomas Hode, Robert E. Nordquist, and Wei R. Chen, "Melanoma patients treated with laser immunotherapy (LIT) and T-cell stimulators (ipilimumab)", Conference of Biophotonics and Immune Responses X, Photonics West, 2015, San Francisco, CA, February 9, 2015.

249. Cody F. Bahavar, Wei R. Chen, Joseph T. Acquaviva, Feifan Zhou, Sheyla Rabei, Aamr Hasanjee, and Roman Wolf, "Thermal cytotoxic effects of laser immunotherapy assisted with cyclophosphamide", Conference of Biophotonics and Immune Responses X, Photonics West, 2015, San Francisco, CA, February 9, 2015.

250. Invited talk Feifan Zhou, Rebaz A. Ahmed, Hong Liu, and Wei R. Chen, "Photo-nano immunotherapy for breast metastatic cancer using synergistic SWNT-GC", Conference of Biophotonics and Immune Responses X, Photonics West, 2015, San Francisco, CA, February 9, 2015.

251. Invited talk Wei R. Chen, "Photo-nano-immunotherapy for cancer treatment", Department of Chemistry, University of Texas, Dallas, February 27, 2015.

Wei R. Chen, Ph.D.

Page 72 of 80

252. Wei R. Chen, “Laser Immunotherapy: Cancer Research @ UCO – A Search for a cure for late-stage, metastatic cancers”, Presentation to Introduction to Biomedical Engineering, University of Central Oklahoma, Edmond, OK, March 26, 2015.

253. Invited talk Wei R. Chen, “Pursuing a Cure for Metastatic Cancer Globally”, Seminar at College of Liberal Arts, University of Central Oklahoma, Edmond, OK, April 7, 2015.

254. Invited talk Wei R. Chen, “Laser Immunotherapy for Treatment of Metastatic Cancers”, Wuhan Optoelectronics Forum, Wuhan National Laboratory for Optoelectronics, April 27, 2015.


256. Wei R. Chen, “Laser-nanotechnology based immunotherapy for cancer treatment”, Chemistry Department, University of Oklahoma, Norman, Oklahoma, September 8, 2015.

257. Invited talk Wei R. Chen, “inCVAX – A biophotonics-based cancer therapy”, Asia Communications and Photonics Conference (ACP2015), Hong Kong, November 22, 2015.

Poster Presentations: 1. Andrea. K. Ives and Wei. R. Chen, “Laser stimulation of tissue”, poster presentation at

Research Day, University of Central Oklahoma, Edmond, Oklahoma, October 8, 1999. 2. Wei. R. Chen and Ahmad El-Samad, “Treatment of metastatic tumors using laser-dye-

immunoadjuvant”, poster presentation at Research Day, University of Central Oklahoma, Edmond, Oklahoma, October 8, 1999.

3. Wei. R. Chen and Robert E. Nordquist, “Treatment of Metastatic Breast Tumors Using Photo Dynamic Immuno Therapy”, poster presentation at Research Day, University of Central Oklahoma, Edmond, Oklahoma, October 27, 2000.

4. Shawn L. Barker, Wei R. Chen, Sarah A. Kimball, and Robert E. Nordquist, “Selective Photothermal Tissue Interaction Using Laser and Laser-Absorbing Dye”, poster presentation at Research Day, University of Central Oklahoma, Edmond, Oklahoma, October 27, 2000.

5. Sarah A. Kimball, Shawn L. Barker, Wei R. Chen, and Robert E. Nordquist, “Selective Photothermal Interaction in Treatment of Deep Tumors Using Laser and Laser-Absorbing Dye”, poster presentation at Graduate Research Education and Technology (GREAT) Symposium, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, March 26-30, 2001.

6. Shawn L. Barker, Sarah A. Kimball, Wei R. Chen, and Robert E. Nordquist, “Using Photo Dynamic Immuno Therapy for the Treatment of Metastatic Breast Tumors”, poster presentation at Graduate Research Education and Technology (GREAT) Symposium, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, March 26-30, 2001.

7. Chris A. Bailey, Evan C. Lemley, and Wei R. Chen, “Mathematical Modeling of Selective Laser-Tissue Interactions Using Monte-Carlo Simulations”, poster presentation at Research Day, University of Central Oklahoma, Edmond, Oklahoma, November 9, 2001.

8. Sang Won Jeong, Fakhrildeen Albahadily, and Wei R. Chen, “MMeeaassuurreemmeenntt ooff OOppttiiccaall PPrrooppeerrttiieess ooff LLaasseerr--AAbbssoorrbbiinngg DDyyee EEnnhhaanncceedd GGeell PPhhaannttoomm ffoorr SSeelleeccttiivvee PPhhoottootthheerrmmaall IInntteerraaccttiioonn”, poster presentation at Research Day, University of Central Oklahoma, Edmond, Oklahoma, November 9, 2001.

9. Jeremy W. Real and Wei R. Chen, “Selective Photothermal Interaction in Tissue-Simulating Gelatin Phantoms”, poster presentation at Research Day, University of Central Oklahoma, Edmond, Oklahoma, November 9, 2001.

Wei R. Chen, Ph.D.

Page 73 of 80

10. Sang Won Jeong, Wei R. Chen, and Fakhrildeen Albahadily, “Measurement of absorption coefficient of chicken breast tissue and selective photothermal interaction”, poster presentation at Research Day, University of Central Oklahoma, Edmond, Oklahoma, October 11, 2002.

1111.. HemanthKumar Athiraman and Wei R. Chen, “Near-Infrared Laser and Laser-Absorbing Dye in Tissue Welding”, poster presentation at Research Day, University of Central Oklahoma, Edmond, Oklahoma, October 11, 2002.

12. Chris Bailey, Evan C. Lemley and Wei R. Chen, “Selective Heating Optimization Using Gel Tissue Phantoms”, poster presentation at Research Day, University of Central Oklahoma, Edmond, Oklahoma, October 11, 2002.

13. Wei R. Chen, Suman Shivakoti, Sang Won Jeong, and HemanthKumar Athiraman “OOppttiimmaall TTeemmppeerraattuurree aanndd LLoonngg--TTeerrmm EEffffeeccttss ooff LLaasseerr TTiissssuuee WWeellddiinngg””, poster presentation at Research Day, University of Central Oklahoma, Edmond, Oklahoma, November 14, 2003.

14. Jared J. Crochet, Kirill Andrienko, Evan C. Lemley, and Wei R. Chen, “Measurement of Thermal Comductivity of Biological Materials from a Known Heat Flux for Laser Tissue Interactions”, poster presentation at Research Day, University of Central Oklahoma, Edmond, Oklahoma, November 14, 2003.

15. Suman Shivakoti, Surya Gyanwali, and Wei R. Chen, “Measurement of absorption and scattering coefficients using integrating sphere technique”, poster presentation at Research Day, University of Central Oklahoma, Edmond, Oklahoma, October 29, 2004.

16. Kirill Andrienko, Jeremy Bjorlie, and Wei R. Chen, “Tissue Property Analysis for Optimal Laser Absorption”, poster presentation at Research Day, University of Central Oklahoma, Edmond, Oklahoma, October 29, 2004.

17. Wei R. Chen, Zheng Huang, Yueqing Gu, Hong Liu, and Hanli Liu, “Monitoring tumor blood flow and vasculature changes during laser photothermal therapy”, The 12th International Congress of Biorheology (12th ICB) and 5th International Conference for Clinical Hemorheology (5th ICCH), Chongqing, China, June 1, 2005.

18. Amir Isbell, Mike Thompson, Eduardo Chini and Wei R. Chen, “NICOTINIC ACID ADENINE DINUCLEOTIDE PHOSPHATE IS PRESENT IN UTERINE SMOOTH MUSCLE MYOMETRIUM AND CAN BE STIMULATED BY HISTAMINE”, Poster Presentation, Sigma Xi Annual Meeting and Student Research Conference, November 3-6, 2005, Seattle, Washington.

19. Surya C. Gnyawali and Wei R. Chen, “Temperature in Biological Tissues Monte Carlo Simulation and Experimental Measurement”, poster presentation at the Oklahoma Research Day, University of Central Oklahoma, Edmond, Oklahoma, November 11, 2005.

20. Yichao Chen, Rheal A. Towner and Wei R. Chen, “Determination of 3D Temperature Distribution During Laser Therapy Using Magnetic Resonance Imaging (MRI)”, poster presentation at the Oklahoma Research Day, University of Central Oklahoma, Edmond, Oklahoma, November 11, 2005.

21. Wei R. Chen, Mark F. Naylor, Amir A. Isbell, “Combination of Laser Irradiation and Immunotherapy for Treatment of Metastatic Tumors”, Biennial Institutional Development Award (IDeA) Program Symposium, Washington, D.C., July 20 - July 22, 2006.

22. Abdiwahab I. Mohamed, Wei R. Chen, Jerry W. Ritchey, and Kenneth E. Bartels, “Immunological Effect of Laser Immunotherapy in Treatment of Metastatic Tumors in Mice”, 2006 INBRE Summer Student Research Poster, University of Oklahoma Health Science Center, July 26, 2006.

23. John F. Barthell and Wei R. Chen, “Residential Summer Bridge – A Success Component of Oklahoma SURE-STEP Program”, National Science Foundation SURE-STEP Conference, Washington, D.C., March, 22-23, 2007.

Wei R. Chen, Ph.D.

Page 74 of 80

24. Surya C. Gnyawali, Yichao Chen, Kandace N. Metcalf, Kenneth E. Bartels, Jerry W. Ritchey, James P. Wicksted, and Wei R. Chen, “Temperature Measurement during Laser-Immunotherapy for Cancer Treatment”, poster presentation at the Oklahoma Research Day, University of Central Oklahoma, Edmond, Oklahoma, April 6, 2007

25. Abdiwahab Mohamed and Wei R. Chen, “Immunological Effect of Laser Immunotherapy in Treatment of Metastatic Tumors in Mice”, poster presentation at the Oklahoma Research Day, University of Central Oklahoma, Edmond, Oklahoma, April 6, 2007.

26. Yichao Chen, Surya Gyanwalib, Chris Bobo, Hong Liu, Yasvir A. Tesiram, Andrew Abbott, Rheal A. Towner, and Wei R. Chen, “3D Thermal Distribution Determination Using Magnetic Resonance Imaging (MRI) During Laser Therapy”, poster presentation at the Oklahoma Research Day, University of Central Oklahoma, Edmond, Oklahoma, April 6, 2007.

27. Abdiwahab Mohamed and Wei R. Chen, “Photothermal Effects during Laser Immunotherapy Treatment of Metastatic Tumors”, Council on Undergraduate Research, Posters on the Hill, Washington, D.C., April 25, 2007.

28. Yichao Chen, Kelvin Le, Halie Ferguso, Henry L, Tamesha Brow, Rheal A. Towner, David Marty, Daniel Resasc, and Wei R. Chen, “SWNT Thermal Performance Under 980nm-Laser Radiation”, poster presentation at Oklahoma Research Day, University of Central Oklahoma, Edmond, Oklahoma, October 26, 2007.

29. Halie Ferguson, Kelvin Le, Tamesha Brown, Deon Peoples, Savanna White, JP Cooper, Henry Le, Yichao Chen, and Wei R. Chen, “Laser Photothermal Interactions for Cancer Treatment”, poster presentation at Oklahoma Research Day, University of Central Oklahoma, Edmond, Oklahoma, October 26, 2007.

30. Robert E. Nordquist, Yichao Chen and Wei R. Chen, “Histological and Morphological Studies of Immune Responses Induced by Laser Immunotherapy” Photonics West 2008, San Jose, California, January 21, 2008.

31. Surya C. Gnyawali, Chandan K. Sen, Kelvin Le, Henry Le and Wei R. Chen, “Thermal Damage in Dye-Enhanced Tissues during Laser Irradiation”, Photonics West 2008, San Jose, California, January 21, 2008.

32. Yingjie. Zhang, Yinyuan Wu, Da Xing, Wei R. Chen, and X. Wang, “PUMA can promote the translocation of Bax via binding to Bcl-Xl during UV-induced apoptosis”, Photonics West 2008, San Jose, California, January 21, 2008.

33. John Barthell, Greg Wilson, Melville, Vaughan, Charles Hughes, and Wei R. Chen, “Summer Bridge Program for STEM Students: Undergraduate Research in Transformative Learning at UCO”, University of Central Oklahoma Share Fair, Edmond, Oklahoma, February 25, 2008.

34. John Barthell, Greg Wilson, Mel Vaughan, and Wei R. Chen, “Oklahoma SURE-STEP Summer Bridge Program: Undergraduate Research and STEM Retention”, National Science Foundation SURE-STEP PI Meeting, Washington, DC, March 6-7, 2008.

35. Stella Onyeri, Sundar Madihally, Ben Lawrence, Aparna Sarasam, Ali Moshfeghian, and Wei R. Chen, “Design of 3-D Chitosan Gelatin Scaffolds for Tissue Engineering”, 2007-2008 Senior Design for Engineering Physics, University of Central Oklahoma, Edmond, Oklahoma, May 5, 2008.

36. Yichao Chen, Yasvir A. Tesiram, Rheal A. Towner, Kelvin Le, Halie Ferguson, and Wei R. Chen, “Dynamic Monitoring of Thermal Effect During Laser Therapy Using Magnetic Resonance Thermometry”, Retreat for INBRE and COBRE Investigators and Students, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, May 9, 2008.

37. Robert E. Nordquist, Henry Le, Chris Bobo, and Wei R. Chen, “Immune Responses Induced by Laser Immunotherapy in Treatment of Metastatic Tumors in Rats”, Retreat for INBRE and

Wei R. Chen, Ph.D.

Page 75 of 80

COBRE Investigators and Students, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, May 9, 2008.

38. Henry Le, Kelvin Le, Halie Ferguson, and Wei R. Chen, “Immune Response Induced by Light-Absorbing Dye, Immunostimulant, and Near-Infrared Laser Irradiation, Oklahoma INBRE Summer Program Presentation, Oklahoma City, Oklahoma, July 25, 2008.

39. Henry Le, Halie Ferguson, Kelvin Le, Yichao Chen, Yasvir A. Tesiram, Rheal A. Towner, and Wei R. Chen, Determination of Thermal Effect of Phototherapy in Cancer Treatment Using Magnetic Resonance Thermometry, IDEA SYMPOSIUM (NISBRE), Washington, DC, August 6-8, 2008.

40. Chris Bobo, Henry Le, Halie Ferguson, and Wei R. Chen, “The effect of tumors after photothermal treatment in stimulating anti-tumor immunological responses”, Oklahoma-Louis Stokes Alliance for Minority Participation (OK-LSAMP) Symposium, Stillwater, Oklahoma, September 20, 2008.

41. Kelvin Le, Philippe Garteiser, Chris Bobo, Daniel Figueroa, Akhee Sarker, and Wei R. Chen, “Dynamic Thermal Mapping Using MRT During Laser Irradiation”, Poster Presentation, Oklahoma Research Day, Broken Arrow, Oklahoma, November 14, 2008.

42. Halie Ferguson, Henry Le, Chet Joshi, Chris Bobo, and Wei R. Chen, “Immunological Responses from Tumors after Laser Immunotherapy”, Poster Presentation, Oklahoma Research Day, Broken Arrow, Oklahoma, November 14, 2008.

43. Lei Liu, Xing Da, and Wei R. Chen, “Involvement of caspase-dependent and -independent apoptotic pathways in cisplatin-induced apoptosis”, Conference of Biophotonics and Immune Responses IV, Photonics West, 2009, San Jose, CA, January 26, 2009.

44. Sheng Song, Xing Da, Feifan Zhou, and Wei R. Chen, “Effect of PDT-treated apoptotic cells on macrophages”, Conference of Biophotonics and Immune Responses IV, Photonics West, 2009, San Jose, CA, January 26, 2009.

45. Henry Le, Halie Ferguson, Chet Joshi, Kelvin Le, Akhee Sarker, and Wei R. Chen, “Anti-tumor Immune Response in Mice Induced by an 805nm Laser, a Light-absorbing Dye and an Immunostimulant”, 14th Annual Oklahoma Research Day at the Capitol, Oklahoma City, OK, February 23, 2009.

46. John F. Barthell, Wei R. Chen, Gregory M. Wilson, Melville B. Vaughan, and Beverly K. Endicott, “Institutionalization of Supplemental Instruction for STEM Majors”, National Science Foundation SURE-STEP PI Meeting, Washington, DC, March 12-13, 2009.

47. Kelvin Le, Phillip Garteiser, Rheal Towner, Akhee Sarkar, “Optimization of magnetic resonance thermometry: a new way to monitor laser photothermal treatment of tumors”, INBRE Summer Posters, Oklahoma City, OK, July 24, 2009.

48. Kelvin Le, Philip Garteiser, Rheal Towner, Akhee Sarker, and Wei R. Chen, “Magnetic Resonance Thermometry Calibration and Thermal Mapping”, Poster Presentation, Oklahoma Research Day, Broken Arrow, Oklahoma, November 13, 2009.

49. Xianwang Wang, Xing Da, Wei R. Chen, Hui Li, “Analysis of GFP-FOXO3a nuclear-cytoplasmic shuttling in ASTC-a-1 cells under growth factor stimulation”, Conference of Biophotonics and Immune Responses V, Photonics West, 2010, San Francisco, CA, January 25, 2010.49. Kelvin Le, Phillip Garteiser, Rheal Towner, Akhee Sarker, and Wei R. Chen, “Magnetic Resonance Thermometry Calibration and Thermal Mapping”, 15th Annual Oklahoma Research Day at the Capitol, Oklahoma City, OK, March 29, 2010.

50. John Barthell, Beverly Endicott, Charlotte Simmons, Melville Vaughan, Greg Wilson, and Wei R. Chen, “Bridges Connecting High Schools, Community Colleges, and Universities for Oklahoma STEM Students”, 2010 NSF STEP Grantee Meeting, Washington, D.C., March 4-5, 2010.

Wei R. Chen, Ph.D.

Page 76 of 80

51. Henry Le, Halie Ferguson, Long Nguyen, Melville Vaughn, Roman F. Wolf, and Wei R. Chen, “Possible Tumor Vaccine Induced by Laser Immunotherapy”, Council on Undergraduate Research, Posters on the Hill, Washington, D.C., April 11, 2010.

52. Kelvin Le, Daniel Figueroa, Phillip Garteiser, Rheal Towner, Akhee Sarker, and Wei R. Chen, “Monitoring Laser Photothermal Therapy Using Magnetic Resonance Thermometry”, National IDeA Symposium of Biomedical, Research Excellence (NISBRE), Washington, DC, June 16-18, 2010.

53. Charlotte K. Simmons, Melville B. Vaughan, John F. Barthell, Gregory M. Wilson, and Wei R. Chen, “STEP@UCO: An Undergraduate Research Program as an Integral Part of Transformative Learning for Students Throughout their College Life in STEM Disciplines”, Council on Undergraduate Research Conference, Ogden, Utah, June 19-22, 2010.

54. Daniel Figueroa, Jonny Walla, Chris Bobo, and Wei R. Chen, “Temperature Measurement in Interstitial Laser Thermotherapy for Treatment of Deeper Tumors”, INBRE Summer Posters, Oklahoma City, OK, July 23, 2010.

55. Rebba Casteel, D. Saunders, T. He, S. Doblas, N. Smith, C. Njoku, X. Li, D. Figueroa, Wei R. Chen, Y. Tesiram, R. A. Towner, “Evaluation of OKN007 for the Treatment of Gliomas Using Magnetic Resonance Imaging”, INBRE Summer Posters, Oklahoma City, OK, July 23, 2010.

56. Daniel Figueroa, Kelvin Le, Jonny Walla, and Wei R. Chen, “Temperature Mapping for Interstitial Laser-Tissue Interaction via Thermal Couples and Magnetic Resonance Thermometry”, Poster Presentation, Oklahoma Research Day, Lawton, Oklahoma, November 12, 2010.

57. Mallory Martin, Jessica Goddard, Destiny Brown, Jessnie Jose, Katie Kastl, Jonny Walla, and Wei R. Chen, “Interstitial Laser Immunotherapy for the Treatment of Metastatic Tumors”, Poster Presentation, Oklahoma Research Day, Lawton, Oklahoma, November 12, 2010.

58. Charlotte K. Simmons, Melville B. Vaughan, John F. Barthell, Gregory M. Wilson, Beverly K. Endicott, and Wei R. Chen, “Faculty Mentoring and Student Retention among STEM Majors”, 2011 NSF STEP Grantee Meeting, Washington, D.C., March 17-18, 2011.

59. Daniel Figueroa, Kelvin Le, Jonny Walla, Jessica Goddard, Rheal A. Towner, Debra Saunders, and Wei R. Chen, “Measurement of photothermal effect in tissues with near-infrared laser delivered by interstitial cylindrical fiber”, Poster Presentation, 16th Oklahoma Research Day at the Capitol, Oklahoma City, Oklahoma, March 31, 2011.

60. Wei R. Chen, Melville B. Vaughan, John F. Barthell, Gregory M. Wilson, Beverly E. Endicott, and Charlotte K. Simmons, “UCO STEP and S-STEM Programs – A Transformative Experience for STEM Majors through Faculty Mentoring and Student Research”, Transformative Learning Conference, University of Central Oklahoma, Edmond, Oklahoma, April 20, 2011.

62. Jessica Goddard, Jessnie Jose, Kelvin Le, Robert E. Nordquist, and Wei R. Chen, “The Photothermal Effects in Tissues Induced by Interstitial Irradiation and Measured by Proton Resonance Frequency”, Oklahoma Research Day, Oklahoma City, Oklahoma, November 4, 2011.

63. John F. Barthell, Charlotte K. Simmons, Gregory M. Wilson, Beverly K. Endicott, and Wei R. Chen, “A student-centered, faculty-driven mechanism to institutionalize STEP bridge activities”, 2012 NSF STEP Grantee Meeting, Washington, D.C., March 15-16, 2012.

64. Wei R. Chen, Panelist, “Implementing Early Undergraduate Research & Internships” Session, 2012 NSF STEP Grantee Meeting, Washington, D.C., March 16, 2012.

65. Wei R. Chen, Feifan Zhou, Xiaosong Li, Jessica D. Goddard, Jessnie Jose, Roman F. Wolf D.V.M., Eric Howard, Tomas Hode, and Hong Liu, “Immune responses induced by immunologically modified carbon nanotube under NIR laser irradiation”, Conference of

Wei R. Chen, Ph.D.

Page 77 of 80

Biophotonics and Immune Responses VIII, Photonics West, 2013, San Francisco, CA, February 4, 2013.

66. Ying-Ling Chen, Wei R. Chen, Fang-Yi Yang, Chung-Yi Wang, and Yi-Jang Lee, “Using immunoadjuvant agent glycated chitosan to enhance anti-tumor immunity induced by HIFU”, Conference of Biophotonics and Immune Responses VIII, Photonics West, 2013, San Francisco, CA, February 4, 2013.

67. Yueqing Gu, Wei R. Chen, and Li Ding, “A bispecific peptide based near-infrared probe for in vivo tumor diagnosis”, Conference of Biophotonics and Immune Responses VIII, Photonics West, 2013, San Francisco, CA, February 4, 2013.

68. Yuxiang Ma, Yuqi Chen, Sisi Cui, Wei R. Chen, and Yueqing Gu, “The preparation and characteristic of a drug carrier for hepatocellular carcinoma-selective targeting”, Conference of Biophotonics and Immune Responses VIII, Photonics West, 2013, San Francisco, CA, February 4, 2013.

69. Aqin Wang, Yuqi Chen, Wei R. Chen, and Yueqing Gu, “Novel 2DG-based harmine derivatives for targeted cancer therapy”, Conference of Biophotonics and Immune Responses VIII, Photonics West, 2013, San Francisco, CA, February 4, 2013.

70. Cody F. Bahavar and Wei R. Chen, “Interstitial Laser Immunotherapy for the treatment of Metastatic Cancer”, 18th Annual Oklahoma Research Day at the Capitol, Oklahoma City, Oklahoma, February 26, 2013.

71. John Barthell, Wei R. Chen, Evan Lemley, and Charlotte Siummons, “Undergraduate research: the focus of the Oklahoma NSF STEP Program and UCO CURE-STEM”, Oklahoma Research Day, University of Central Oklahoma, Edmond, Oklahoma, March 8, 2013.

72. Ying-Ling Chen, Feng-Yi Yang, Yi-Jang Lee, Joseph T. Acquaviva III, and Ellen Boarman, and Wei R. Chen, “Anti-tumor immunity induced by combination of glycated chitosan and high intensity focused ultrasound”, Oklahoma Research Day, University of Central Oklahoma, Edmond, Oklahoma, March 8, 2013.

73. Cuixia Lu, Da Xing, Joseph T. Acquaviva III, Ellen Boarman

and Wei R. Chen, “Nitric oxide production in macrophages induced by tumor cells after high-fluence low power laser irradiation”, Oklahoma Research Day, University of Central Oklahoma, Edmond, Oklahoma, March 8, 2013.

74. Joseph T. Acquaviva, Mark F. Naylor, Robert E. Nordquist, John A. Lunn, Tomas Hode, Wei R. Chen, “Laser immunotherapy in the treatment of late-stage, metastatic melanoma patients”, Oklahoma Research Day, University of Central Oklahoma, Edmond, Oklahoma, March 8, 2013.

75. Cody Bahavar, Tomas Hode, Robert E. Nordquist, and Wei R. Chen, “Mechanism of laser immunotherapy in treatment of late-stage, metastatic breast cancer patients”, Oklahoma Research Day, University of Central Oklahoma, Edmond, Oklahoma, March 8, 2013.

76. Zhifang Li, Yubing Liu, Hui Zhang, Xiaona Lin, Hui Li, and Wei R. Chen, “Photoacoustic imaging in determination of tissue temperature during laser irradiation”, Oklahoma Research Day, University of Central Oklahoma, Edmond, Oklahoma, March 8, 2013.

77. Okhil Nag and Wei R. Chen, “Synthesis and Optical Properties of pH-Responsive Novel Conjugated Polyampholytes”, Oklahoma Research Day, University of Central Oklahoma, Edmond, Oklahoma, March 8, 2013.

78. Brock K. Henderson, Ryan Griswold, Erica Halterman, Joseph Acquaviva III and Wei R. Chen, “Photothermal effects of glycated chitosan bound to single-walled carbon nanotubes”, Oklahoma Research Day, University of Central Oklahoma, Edmond, Oklahoma, March 8, 2013.

Wei R. Chen, Ph.D.

Page 78 of 80

79. Cody Bahavar, Jessica Goddard, Allie Sikes, Ellen Boarman, Robert E. Nordquist, Rheal Towner, and Wei R. Chen, “Effects of glycated chitosan on interstitial laser immunotherapy for the treatment of metastatic cancer”, Oklahoma Research Day, University of Central Oklahoma, Edmond, Oklahoma, March 8, 2013.

80. Lance Straughn, Shayla Pearson, Amanda Walker, and Wei R. Chen, “Design of a Temperature Measurement and Acquisition Device to be Used in Conjunction with Laser Photothermal Therapy”, Oklahoma Research Day, University of Central Oklahoma, Edmond, Oklahoma, March 8, 2013.

81. John Barthell, Wei R. Chen, Beverly Endicott, Charles Hughes, William Radke, Charlotte Simmons, Gregory Wilson, “CURE-STEM: A Model for Encouraging and Sustaining a Culture of Student-Centered Research”, Oklahoma Research Day, University of Central Oklahoma, Edmond, Oklahoma, March 8, 2013.

82. Joseph T. Acquaviva, Ellen Boarman, and Wei R. Chen, “Cellular anti-tumor immunological responses induced by laser immunotherapy with immunologically modified carbon nanotubes”, Oklahoma Research Day, University of Central Oklahoma, Edmond, Oklahoma, March 8, 2013.

83. John F. Barthell, Charlotte K. Simmons, Gregory M. Wilson, Evan A. Lemley, and Wei R. Chen, “Faculty and Students: Two Foci of Undergraduate Research – the Oklahoma STEP Program”, 2013 NSF STEP Grantee Meeting, Washington, D.C., March 14-15, 2013.

84. Joseph Acquaviva and Wei R. Chen, " Thermal Effects of Immunologically Modified Carbon Nanotubes for the Treatment of Metastatic Cancer”, 2013 NBRE Summer Student Research Poster, University of Oklahoma Health Science Center, July 19, 2013.

85. Feifan Zhou, Joseph T. Acquaviva III, and Wei R. Chen, "Immunologically Modified Carbon Nanotube: A Novel Structure for Laser Cancer Therapy", Stephenson Cancer Center Annual Research Symposium, University of Oklahoma Stephenson Cancer Center, Oklahoma City, Oklahoma, January 31, 2014.

86. Joseph T. Acquaviva III, Feifan Zhou, Wei R. Chen, Tomas Hode, and Hong Liu, "Nanotechnology and phototherapy for cancer treatment", Conference of Biophotonics and Immune Responses IX, Photonics West, 2014, San Francisco, CA, February 3, 2014.

87. Wei R. Chen, Robert E. Nordquist, Tomas Hode, Hong Liu, and Feifan Zhou, "Mechanistic studies of systemic immune responses induced by laser-nanotechnology", Conference of Biophotonics and Immune Responses IX, Photonics West, 2014, San Francisco, CA, February 3, 2014.

88. Sheng Song Wei R. Chen, and Feifan Zhou, "Low-power laser irradiation (LPLI) attenuates microglial cytotoxicity through the activation of Src pathway", Conference of Biophotonics and Immune Responses IX, Photonics West, 2014, San Francisco, CA, February 3, 2014.

89. John F. Barthell, Charlotte K. Simmons, Gregory M. Wilson, Beverly K. Endicott, Evan A. Lemley, and Wei R. Chen, “Sustaining STEP activities through internal resources and external funding and through faculty development and student support”, 2014 NSF STEP Grantee Meeting, Washington, D.C., March 6, 2014.

90. Zhifang Li, Xiaona Lin, Hui Li, and Wei R. Chen, “Imaging biological tissues with optical coherent tomography based elastography”, Oklahoma Research Day, University of Central Oklahoma, Edmond, Oklahoma, March 7, 2014.

91. Feifan Zhou, Sheng Song, and Wei R. Chen, “Suppression of microglial-induced neuroinflammation in LPS-activated microglia by low-power laser irradiation (LPLI)”, Oklahoma Research Day, University of Central Oklahoma, Edmond, Oklahoma, March 7, 2014.

Wei R. Chen, Ph.D.

Page 79 of 80

92. Wei R. Chen, Feifan Zhou, and Robert E. Nordquist, “Biological mechanism of nanotechnology and near-infrared laser irradiation”, Oklahoma Research Day, University of Central Oklahoma, Edmond, Oklahoma, March 7, 2014.

93. Joseph T. Acquaviva III, Ethan W. Wood, Wei R. Chen, and Melville B. Vaughan, "Effects of Laser Immunotherapy on the Microenvironment of Tumors", Oklahoma Research Day, University of Central Oklahoma, Edmond, Oklahoma, March 7, 2014.

94. Cody Bahavar, Robert E. Nordquist, Hong Liu, and Wei R. Chen, "Effects of Cyclophosphamide on Laser Immunotherapy for the Treatment of Metastatic Cancer", 1st CIBER Symposium, College of Mathematics and Science, University of Central Oklahoma, Edmond, Oklahoma, March 8, 2014.

95. Joseph T. Acquaviva III, Bailey Vasquez, Feifan Zhou, and Wei R. Chen, "Nanotechnology and Phototherapy: A Novel Treatment Modality for Metastatic Cancers", 1st CIBER Symposium, College of Mathematics and Science, University of Central Oklahoma, Edmond, Oklahoma, March 8, 2014.

96. Bryan A. Dawkins, Sean M. Laverty, and Wei R. Chen, "Dynamics of Laser-Initiated Immunotherapy of Cancer", 1st CIBER Symposium, College of Mathematics and Science, University of Central Oklahoma, Edmond, Oklahoma, March 8, 2014.

97. Joseph T. Acquaviva III and Wei R. Chen, “Treatment of Metastatic Cancers with Immunologically Modified Carbon Nanotubes”, 19th Annual Oklahoma Research Day at the Capitol, Oklahoma City, Oklahoma, April 1, 2014.

98. Joseph T. Acquaviva III and Wei R. Chen, “Treatment of Metastatic Cancers with Immunologically Modified Carbon Nanotubes”, Beta Beta Beta Biological Honor Society Southcentral Regional Convention, April 4, 2014.

99. Feifan Zhou, Aamr Hasanjee, and Wei R. Chen, "Photo-Nano Immunotherapy for Metastatic Breast Cancer", Stephenson Cancer Center Annual Research Symposium, University of Oklahoma Stephenson Cancer Center, Oklahoma City, Oklahoma, January 28, 2015.

100. Zhifang Li, Hui Li, and Wei R. Chen, "Temperature simulation of photothermal therapy in different size of tumors", Conference of Biophotonics and Immune Responses X, Photonics West, 2015, San Francisco, CA, February 9, 2015.

101. Cody F. Bahavar, Aamr Hasanjee, Feifan Zhou, Rebaz A. Ahmed, Sheyla Rabei, Hong Liu, and Wei R. Chen, "Effects of laser immunotherapy for the treatment of metastatic tumor cells", Conference of Biophotonics and Immune Responses X, Photonics West, 2015, San Francisco, CA, February 9, 2015.

102. Joseph T. Acquaviva, Cody F. Bahavar, Aamr Hasanjee, Fefian Zhou, Roman F. Wolf, Eric W. Howard, and Wei R. Chen, "In vivo efficacy studies of immunologically modified carbon nanotubes and phototherapy against rat tumors", Conference of Biophotonics and Immune Responses X, Photonics West, 2015, San Francisco, CA, February 9, 2015.

103. Chun-Yuan Chang, Yi-Jang Lee, Wei R. Chen, and Jyh-Der Leu, "The combination of radiotherapy and immunotherapy using glycated chitosan as an immunological stimulant", Conference of Biophotonics and Immune Responses X, Photonics West, 2015, San Francisco, CA, February 9, 2015.

104. Di Wu, Molly Wong, Yuhua Li, Wei R. Chen, Xizeng Wu, Hong Liu, "DQE characterization of a high-energy in-line phase contrast prototype under different kVp and beam filtration", Conference of Biophotonics and Immune Responses X, Photonics West, 2015, San Francisco, CA, February 9, 2015.

105. Aamr M. Hasanjee, Joseph T. Acquaviva III, Cody F. Bahavar, Austin Doughty, Connor West, Erica Halterman, Feifan Zhou, and Wei R. Chen, "Induction of Anti-tumor Immune Response by Noninvasive Laser Irradiation and Immunologically Modified Carbon Nanotubes using

Wei R. Chen, Ph.D.

Page 80 of 80

Mammary Tumor Model in Rats", Oklahoma Research Day, Northeastern State University, Tahlequah, Oklahoma, March 13, 2015.

106. Austin Doughty, Aamr Hassanjee, Cody Bahavar, Rheal Towner, Nataliya Smith, Debra Saunders, and Wei R. Chen, "Development of a novel tracking method for tumor metastases using MRI and molecularly-targeted contrast agents", Oklahoma Research Day, Northeastern State University, Tahlequah, Oklahoma, March 13, 2015.

107. Cody F. Bahavar Aamr Hassanjee, and Wei R. Chen, "Thermal cytotoxic effects of laser immunotherapy assisted with Low-dose cyclophosphamide", Oklahoma Research Day, Northeastern State University, Tahlequah, Oklahoma, March 13, 2015.

108. Aamr M. Hasanjee, Joseph T. Acquaviva III, Cody F. Bahavar, Austin Doughty, Connor West, Erica Halterman, Feifan Zhou, and Wei R. Chen, "Induction of Anti-tumor Immune Response by Noninvasive Laser Irradiation and Immunologically Modified Carbon Nanotubes using Mammary Tumor Model in Rats", 2nd CIBER Symposium, College of Mathematics and Science, University of Central Oklahoma, Edmond, Oklahoma, April 5, 2015.

109. Austin Doughty, Aamr Hassanjee, Cody Bahavar, Rheal Towner, Nataliya Smith, Debra Saunders, and Wei R. Chen, "Development of a novel tracking method for tumor metastases using MRI and molecularly-targeted contrast agents", 2nd CIBER Symposium, College of Mathematics and Science, University of Central Oklahoma, Edmond, Oklahoma, April 5, 2015.

110. Aamr M. Hasanjee, Joseph T. Acquaviva III, Cody F. Bahavar, Feifan Zhou, and Wei R. Chen, "Effects of Treatment Duration on Anti-tumor Response Induced by Non-invasive Laser Immunotherapy", 2015 INBRE Summer Student Research Poster, University of Oklahoma Health Science Center, July 17, 2015.

Documents

VITAEblasts.uco.edu/centralities/files/CMS - Chen CV.pdfWei R. Chen, Ph.D. Page 2 of 80 Central Oklahoma Alliance for Physics Teaching, 1992-1996 Vice Chair, 1992-1993; Chair, 1993-1994