Upload
ariel-nicholson
View
214
Download
0
Embed Size (px)
Citation preview
©
Modeling Obesity Using Abductive Networks
Abdel-Aal, RE; Mangoud, AM
ACADEMIC PRESS INC, COMPUTERS AND BIOMEDICAL RESEARCH; pp: 451-471;
Vol: 30
King Fahd University of Petroleum & Minerals
http://www.kfupm.edu.sa
Summary
This paper investigates the use of abductive-network machine learning for modeling
and predicting outcome parameters in terms of input parameters in medical survey
data. Here we consider modeling obesity as represented by the waist-to-hip ratio
(WHR) risk factor to investigate the influence of various parameters. The same
approach would be useful in predicting values of clinical parameters that are difficult
or expensive to measure from others that are more readily available. The AIM
abductive network machine learning tool was used to model the WHR from 13 other
health parameters. Survey data were collected for a randomly selected sample of 1100
persons aged 20 yr and over attending nine primary health care centers at Al-Khobar,
Saudi Arabia. Models were synthesized by training on a randomly selected set of 800
cases, using both continuous and categorical representations of the parameters, and
evaluated by predicting the WHR value for the remaining 300 cases. Models for
WHR as a continuous variable predict the actual values within an error of 7.5% at the
90% confidence limits. Categorical models predict the correct logical value of WHR
with an error in only 2 of the 300 evaluation cases. Analytical relationships derived
from simple categorical models explain global observations on the total survey
population to an accuracy as high as 99%. Simple continuous models represented as
analytical functions highlight global relationships and trends. Results confirm the
strong correlation between WHR and diastolic blood pressure, cholesterol level, and
family history of obesity. Compared to other statistical and neural network
approaches, AIM abductive networks provide faster and more automated model
synthesis. A review is given of other areas where the proposed modeling approach can
be useful in clinical practice. (C) 1997 Academic Press.
Copyright: King Fahd University of Petroleum & Minerals;http://www.kfupm.edu.sa
1.2.3.4.5.6.7.8.9.10.11.12.13.14.15.16.17.18.19.20.21.22.23.24.25.26.27.28.29.30.31.32.33.34.35.36.37.38.39.40.41.42.43.
©
References:*ABT CORP, 1990, AIM US MANABDELAAL RE, 1994, ENERGY, V19, P739ABDELAAL RE, 1995, WEATHER FORECAST, V10, P310ABDELHALIM RE, 1993, SCAND J UROL NEPHROL, V27, P155ALLAIN CC, 1974, CLIN CHEM, V20, P470BARRON AR, 1984, SELF ORG METHODS MODBARRON RL, 1984, SELF ORG METHODS MODBAUMGARTNER RN, 1987, AM J EPIDEMIOL, V126, P614BRAY GA, 1988, W J MED, V149, P429BREIMAN L, 1984, CLASSIFICATION REGREBUCOLO G, 1973, CLIN CHEM, V19, P476CHARALAMBOUS C, 1992, IEE PROC-G, V139, P301DANIEL WW, 1974, BIOSTATISTICS FDN ANDENTONKELAAR I, 1990, NED TIJDSCHR GENEESK, V134, P1900DOYLE HR, 1995, METHOD INFORM MED, V34, P253DUCIMETIERE P, 1986, INT J OBESITY, V10, P229DUDA R, 1973, PATTERN RECOGNITIONFARLOW SJ, 1984, SELF ORG METHODS MODFOLSOM AR, 1990, AM J EPIDEMIOL, V131, P794HAFFNER SM, 1987, DIABETES, V36, P43HARTZ AJ, 1992, AM J CARDIOL, V70, P179IKEDA S, 1984, SELF ORG METHODS MODIVAKHNENKO AG, 1971, IEEE T SYST MAN CYB, V1, P364KAPLAN NM, 1989, ARCH INTERN MED, V149, P1514KENNEDY RL, 1990, CLIN SCI, V78, P24KEYS A, 1972, J CHRON DIS, V25, P329KISSEBAH AH, 1982, J CLIN ENDOCR METAB, V54, P254KNERR S, 1990, NEUROCOMPUTING ALGORKROTKIEWSKI M, 1983, J CLIN INVEST, V72, P1150LAPIDUS L, 1984, BRIT MED J, V289, P1261LAPIDUS L, 1988, INT J OBESITY, V12, P361LAPUERTA P, 1995, COMPUT BIOMED RES, V28, P38LAWS A, 1990, AM J PUBLIC HEALTH, V80, P1358LOWELL WE, 1994, J AM MED INFORM ASSN, V1, P459MALONE JM, 1984, SELF ORG METHODS MODMARSHAL SJ, P 2 INT C ART NEUR N, P200MOENS HJB, 1991, METHOD INFORM MED, V30, P187MONTGOMERY DC, 1985, INTRO LINEAR REGRESSMONTGOMERY GJ, P SPIE APPL ART NEUR, P56MYKKANEN L, 1993, DIABETOLOGIA, V36, P553OHLSON LO, 1985, DIABETES, V34, P1055OWENS A, P INT C NEUR NETW WA, P381
QUINLAN JR, 1987, INT J MAN MACH STUD, V27, P221Copyright: King Fahd University of Petroleum & Minerals;
http://www.kfupm.edu.sa
44.45.46.47.48.49.50.51.52.53.54.55.
©
REVICKI DA, 1986, AM J PUBLIC HEALTH, V76, P992RUMELHART D, 1986, PARALLEL DISTRIBUTEDSCOTT DE, 1984, SELF ORG METHODS MODSOLER JT, 1988, J CLIN EPIDEMIOL, V41, P1075SZOLOVITS P, 1978, ARTIF INTELL, V11, P115VANSANT G, 1988, INT J OBESITY, V12, P133WADDEN TA, 1988, AM J CLIN NUTR, V47, P229WARNICK GR, 1978, J LIPID RES, V19, P65WEISS SM, 1991, COMPUTER SYSTEMS LEAWOOLERY LK, 1994, J AM MED INFORM ASSN, V1, P439WU YZ, 1993, RADIOLOGY, V187, P81ZHU K, P 2 INT C ART NEUR N, P205
For pre-prints please write to: [email protected]
Copyright: King Fahd University of Petroleum & Minerals;http://www.kfupm.edu.sa