UMELISA

Birth defectsDown syndromeCongenital hypothyroidismPhenylketonuriaBiotinidase deficiencyHIV 1+2Hepatitis BHepatitis CHTLV I +IIChagas diseaseDengueLeprosyTetanusToxoplasmosisAllergy

37

47

38

66

366

2

1

1

NATIONAL SCREENING AND NATIONAL SCREENING AND OTHER SPECIAL PROGRAMS IN OTHER SPECIAL PROGRAMS IN

CUBACUBA

•Mother - ChildMother - Child

•Blood CertificationBlood Certification

•Epidemiological SurveillanceEpidemiological Surveillance

•Placenta CertificationPlacenta Certification

•Minimum access neurosurgeryMinimum access neurosurgery

Severe Birth Defects

HIV

Hepatitis B

Hepatitis C

Congenital Hypothyroidism

Phenilketonuria

Biotinidase Def. (2002)

Galactosemia (2002)

Congenital Adrenal H. (2003)

Others

CUBAN CUBAN PRENATAL PROGRAMSPRENATAL PROGRAMS

RESULTS.RESULTS.

Pregnants Screened:Pregnants Screened: 2 524 1632 524 163

Birth Defects Detected:Birth Defects Detected: 5 2665 266

Cuba 1986 – 2001Cuba 1986 – 2001

Only 1 mother to child HIV transmission since 1997Only 1 mother to child HIV transmission since 1997

No mother to child HBV transmission in 95%No mother to child HBV transmission in 95%

2.08 x 10002.08 x 1000

CONGENITAL HYPOTHYROIDISMCONGENITAL HYPOTHYROIDISMCUBAN SCREENING PROGRAM.CUBAN SCREENING PROGRAM.

• Newborns Screened:Newborns Screened: 2 108 2882 108 288

• Hypothyroidism:Hypothyroidism: 641641• Permanent:Permanent: 325 325• Transitory:Transitory: 203 203 • Under study:Under study: 113 113

Incidence:Incidence: 1 : 32951 : 3295

Cuba 1986 – 9 -Cuba 1986 – 9 -20012001

BLOOD CERTIFICATION ANDBLOOD CERTIFICATION ANDSEROLOGICAL SURVEILLANCESEROLOGICAL SURVEILLANCE

HIV1+2, HBsAg, HCV, DENGUE, CHAGASHIV1+2, HBsAg, HCV, DENGUE, CHAGAS

17,824,040UMELISA

13,568,060

7,314,844

++- - +-

Negativeno further action

Negativeno further action

1 2

BL OO D

DIS CA RD

- -- - ++ +++-- -

++- - +-Negative

no further action

++- - +-Negative

no further actionFollow Up6 m onths

A B WHO

HIV SCREENING ALGORITHM

VIH 1 and VIH 2 cases detectedVIH 1 and VIH 2 cases detectedMore than 20 million testedMore than 20 million tested

0

100

200

300

400

500

600

700

1986 1988 1990 1992 1994 1996 1998 2000

VIH 1

VIH 2

Year

Ser

opos

itiv

es

DAVIH SUMA

DETECTED4072

LIVING WITHHIV/AIDS

3022