€¦ · Web viewIsolation of bioactive plant constituents using advanced chromatographic techniques (separation on VLC, and column chromatography using different adsorbent as RP,

Cairo University

Faculty of PharmacyCurriculum Vitae

Education Academic DegreesPhD

(Pharmacognosy/ Phytochemical and Biological Studies of Certain Species Belonging to the Genera Dimorphotheca, Gazania and Helichrysum (Family Compositae) Growing in Egypt,2007, Cairo University)

Master

(Pharmacognosy/ Pharmacognostical Study of Certain Foeniculum species Growing in Egypt Family Umbelliferae, 2003, Cairo University)

Bachelor

Choose DegreePharmaceutical science/1998, Cairo University

Research interestPhytochemical and biological studies of Medicinal Plants.

Isolation of bioactive plant constituents using advanced chromatographic techniques (separation on VLC, and column chromatography using different adsorbent as RP, Sephadex, Cellulose, or Polyamide and separation using PC) and elucidation of their structure using different chemical and spectral methods (UV, IR, 1H-NMR, 13C-NMR, H,H-COSY, HMQC, EI-MS, ESI-MS).

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Insert Your ImageName: Shahira Mohammed Ezzat Mohammed El-Komy

Title: Associate Professor Dr.

Department:

Pharmacognosy

E-mail: [email protected]

Website: scholar.google.com.eg

Mobile: +2 01000781836

Phone: +202 23932452

Cairo University


Teaching Course Title

Undergraduate Courses(General Program)

206 Phytochemistry II

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Undergraduate Courses (Clinical Program)

PG 505 Phytochemistry-2

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Choose anitem.Postgraduate

Courses

Spectroscopy of Natural Products (NMR, UV, MS and IR) (2204)

Career History and Professional ExperienceTitles 07/2012-present, Associate Professor.

05/2007-07/2012, Assistant Professor.

12/2003-05/2007, Associate lecturer

11/1998-12/2003, Teaching assistant

Awards 1. Outstanding Presentation for Poster presented by The 4th International Euro-Med Conference of Natural Products (BioNat IV) Cairo-Sharm ElSheikh (March 2015).

2. Appreciation certificate for International Publications from Cairo University 2014.

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Cairo University



4. Outstanding Presentation for Poster presented by 3rd World Congress on Cancer

Science & Therapy. OMICs group, San Fransisco, California, USA (October 2013).

5. Abdel Azeem Hefny Saber Award for the best Research article of Pharmacognosy

Departments for the year 2012/2013 (May 2013).



8. Prize of recognition in scientific publishing for staff members 1432/1433 from

University of King AbdulAziz for the scientific paper “Effect of the Method of

Preparation on the Composition and Cytotoxic Activity of the Essential Oil of

Pituranthos tortuosus. Z. Naturforsch, 66 c, 143-148 (2011)”.

9. Appreciation certificate for the unique efforts done for the improvement of the work

level in Faculty of Pharmacy Cairo University 2010/2011.

10. Appreciation certificate for contribution in the development of Electronic Learning

System (ELS) from El-Nahda University in Beni Sweif (NUB) 2008/2009-2009/2010.

11. Prize of recognition in scientific publishing for staff members 1430/1431 from

University of King AbdulAziz for the scientific paper “Chemical and Biological

Investigation of Araucaria heterophylla Salisb. Resin. Z. Naturforsch, 64 c, 819-823

(2009)”.

12. Appreciation certificate from the Egyptian Pharmacists Syndicate for the distinctive

role and efforts exerted in the profession of pharmacy (2008).

13. Appreciation certificate from “The Center of Quality Assurance and Accreditation, Cairo

University” for the positive sharing in the first International Conference entitled

“Quality Assurance and Accreditation between reality and Ambitions” (April 2008).

14. Cairo University Award for the best PH.D. Thesis (2007/2008).

15. Abdel Azeem Hefny Saber Award for the best PH.D. Thesis of Pharmacognosy

Departments (2007/2008).

16. Shield of Excellence from the Egyptian Pharmacists Syndicate for access the doctoral

(2007/2008).

17. Exemplar Teaching Assistant from Club of Cairo University Staff (2004/2005).

Projects Development of Flax seeds Lignans as nutraceutical in prevention and treatment of

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Cairo University


cancers (January 2014/December 2016) funded by Cairo University. High value Pharmaceutical Raw Material from Food Processing Waste (2014/2016)

Funded by STDF National Research Grants

Environmental pollutions and obesogens: Role of clinical nutrition and natural

products in treatment of obesity and diabetes mellitus. Funded by the National

Research Center (2013/2016).

Production of pharmacologically active materials from medicinal plant resources in Egypt. (2008-2010) funded by Cairo University

Publications and Presentations

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El-Hawary, S.S., Ezzat, S.M., Eid, G.E., Abd-El Rhman, S.K. (2015).Effect of certain

essential oils on dissolution of three commercial gutta-percha brands. Journal of Essential Oil

Bearing Plants. 18 (5), 1126 - 1137

Ezzat, S.M., Choucry, M.A., Kandil, Z.A. (2015). Antibacterial, antioxidant, and topical anti-

inflammatory activities of Bergia ammannioides: A wound-healing plant. Pharm Biol, Early Online: 1–

10, DOI: 10.3109/13880209.2015.1028079.

Ezzat, S.M., Salama M.M. (2014): A new α- glucosidase inhibitor from Achillea fragrantissima

(Forssk.) Sch. Bip growing in Egypt. Natural Product Research, 28 (11), 812-818.

Motaal, A.A., Ezzat, S.M., El-Askary, H.I. (2014). Antihyperglycemic activity and standardization of the

bioactive extract of Cleome droserifolia growing in Egypt. Pharmacognosy Journal. 6 (5), 15-21.

El-Askary, H.I., El-Kashoury, E.A., Kandil, Z.A., Ezzat, S.M., Salem, M.A., Sleem A.A.

(2014). Chemical and biological study of Mentha suaveolens Ehrh. cultivated in Egypt.

Journal of Medicinal Plant Research.8 (20), 747-755.

El-Askary, H.I., El-Kashoury, E.A., Kandil, Z.A., Salem, M.A., Ezzat, S.M. Biological activity and

standardization of the ethanolic extract of the aerial parts of Mentha Suaveolens Ehrh. (2014).World

Journal of Pharmacy and Pharmaceutical Sciences (WJPPS). 3 (6),223-241.

Ezzat, S.M., Abdel-Sattar, E., Harraz, F.M., Ghareib, S.A. (2014). Antihyperglycemic and

antihyperlipidaemic effects of the methanol extracts of Cleome ramosissima Parl., Barleria bispinosa

(Forssk.) Vahl. and Tribulus macropterus Boiss. Bulletin of Faculty of Pharmacy, Cairo University

(BFOPCU), 52, 1-7

Please write down your books, book chapters, publications and conference presentations here as per “Bulletin of Faculty of

Cairo University


Alrazhi, B.A., Diab, A.H., Essa, S.A., Ahmed G.M., Ezzat S.A. (2014). Antibacterial activity of the ethanolic

extracts of Allium sativum l. Bulbs and zingiber officinale roscoe rhizomes as irrigating solutions. World

Journal of Pharmacy and Pharmaceutical Sciences (WJPPS). 3 (6), 324-336.

Salama, M.M., Ezzat, S.M., Salah El Dine, R., El-Sayed, A.M., Sleem A.A. (2013): new bioactive

metabolites from a crown gall induced on an Eucalyptus tereticornis Sm. Tree. Z. Naturforsch. 68c, 461 –

470.

Shabana, M.M., Salama, M.M., Ezzat, S.M., Ismail, L.R. (2013): In vitro and in vivo anticancer activity of

the fruit peels of Solanum melongena L. against hepatocellular carcinoma. Journal of Carcinogenesis &

Mutagenesis, 4 (3).

EL-Hawary, S., EL-Shabrawy, A., Ezzat, S.M., EL-Shibany, F. (2013): Gas chromatography-mass

spectrometry analysis, hepatoprotective and antioxidant activities of the essential oils of four Libyan

herbs. Journal of Medicinal Plants Research, 7, 1746-1753.

Abdallah, H.M., Ezzat, S.M., Salah El Dine, R., Abdel-Sattar, E., Abdel-Naim,A.B. (2013). Protective effect

of Echinops galalensis against CCl4-induced injury on the human hepatoma cell line (Huh7).

Phytochemistry Letters, 6, 73–78.

Ezzat, S.M., Motaal, A.A. (2012): Isolation of New Cytotoxic Metabolites from Cleome droserifolia

Growing In Egypt. Z. Naturforsch 67c, 266-274 (2012).

Hifnawy, S.M., Sokkar, N.M., Ezzat, S.M., Raslan, M.M., Salib, J.Y., Sleem, A.A. (2012): Cytotoxicity and

suppressive effect of leaves of Mimusops Laurifolia on carbon tetrachloirde-induced liver injury in rats

and its bioactive constituents. 11 (3), 124-130.

An abstract: Abdel Motaal, A.A., Ezzat, S.M., El-Alfy, T.S., El-Askary, H.I. (2012): A Validated HPLC

Method for Standardization of The Most Active Fraction of The Antihyperglycemic Drug Cleome

droserifolia using Bioactive Markers. Planta Medica, 77, 1235.

El-Alfy, T.S., Ezzat, S.M., Sleem, A.A. (2012): Chemical and biological study of the seeds of Eragrostis tef

(zucc.) Trotter. Natural Product Research. 26 (7), 619-629.

Ezzat, S.M., Abdallah, H.M., Fawzy,G.A., EL Maraghy, S.A. (2012): Hepatoprotective Constituents of

Torilis radiata Moench. (Apiaceae). Natural Product Research, 26 (3), 282-285.

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Motaal, A.A., Ezzat, S.M., Haddad, P.S. (2011): Determination of Bioactive Markers in Cleome

droserifolia using Cell-Based Bioassays for Antidiabetic Activity and Isolation of two Novel Active

Compounds. Phytomedicine, 19, 38-41.

Salama, M.M., Ezzat, S.M., Sleem, A.A. (2011): A new flavones glycoside from the flowers of Onopordum

alexandrinum growing in Egypt. Z. Naturforsch, 66 c, 251-259.

Abdallah, H.M., Ezzat, S.M. (2011): Effect of the Method of Preparation on the Composition and

Cytotoxic Activity of the Essential Oil of Pituranthos tortuosus. Z. Naturforsch, 66 c, 143-148.

El-Alfy, T.S., Ezzat, S.M., Hegazy, A.K., Amer, A.M.M., Kamel, G.M. (2011): Isolation of Biologically Active

Constituents from Moringa peregrina (Forssk.) Fiori. (Family Moringaceae) Growing in Egypt.

Pharmacognosy Magazine, 7 (26), 106-112.

El-Sayed, A.M., Ezzat, S.M., Salama, M.M., Sleem, A.A. (2011): Hepatoprotective and cytotoxic activities

of Delonix regia flower extracts. Pharmacognosy Journal, 3 (19), 49-56.

Ezzat, S.M., Salama, M.M., Sleem, A.A. (2010). Antiulcerogenic activity of the essential oil of the roots of

Ocimum basilicum L. var. minimum. International Journal of Essential Oil Therapeutics. 4, 137-142.

El-Hawary, S.S., El-Shabrawy, A.O., Ezzat, S.M, El-Shibany, F.A. (2010). Macro- and Micromorphology of

Certain Plants growing in Libya Belonging to Family Lamiaceae.Egypt.J. Biomed.Sci. 34, 133-161.

Michel, C.G., El-Dine N.S., Fahmy S.M., Ezzat, S.M., Nesseem, D.I., El-Alfy, T.S. (2010): Phytochemical and

biological investigation of the extracts of Nigella sativa L. seed waste. Drug Testing and Analysis.

Published online in Wiley Online Library.

Abdel-Sattar, E., Abdel Monem, A.R., Ezzat, S.M., El-Halawany, A.M., Mouneir, S.M. (2009): Chemical

and Biological Investigation of Araucaria heterophylla Salisb. Resin. Z. Naturforsch, 64 c, 819-823.

Youssif, M.F., Eid, H.H., Ezzat, S.M. (2009). Cytotoxic Sterols and Triterpenes from Ficus binnendikii

(Mio.)Miq. Cultivated in Egypt. J. Biomed. Sci., 29 , 241-48.

El-Alfy, T.S. Hetta, M.H., Ezzat, S.M., Sleem, A.A. (2008). Pharmacognostical and biological studies on

the rhizomes of Gazania nivea DC. cultivated in Egypt. Bull. Fac. Pharm. Cairo Univ., 46 (2), 263-75.

Soliman, F. M., Shehata. A. H., Khaleel, A. E., Ezzat, S. M., Sleem, A.A. (2008). Caffeoyl Derivatives and

Flavonoids from Three Compositae Species. Pharmacognosy Magazine, 4 (13), 1-11.

Soliman, F. M., Shehata. A. H., Khaleel, A. E., Ezzat, S. M. (2007). A new γ-pyrone, sterols and triterpenes

from Helichrysum bracteatum, Gazania nivea and Dimorphotheca ecklonis. Pharmacognosy Magazine, 3

(12), 214-218.

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Cairo University


Soliman, F. M., Shehata. A. H., Khaleel, A. E., Ezzat, S. M., Abdel-Aaty, A. M. (2004). Botanical and

Biological Studies of Foeniculum vulgare Mill. and Foeniculum dulce DC. Growing in Egypt. Bull. Fac.

Pharm Cairo Univ., 42(1), 113-137 (2004).

Soliman, F. M., Shehata. A. H., Khaleel, A. E., Ezzat, S. M. (2004). Lipids and Coumarins of Foeniculum

vulgare Mill. and Foeniculum dulce DC. J. Biomed. Sci., 14,148-166.

Soliman, F. M., Shehata. A. H., Khaleel, A. E., Ezzat, S. M. (2002). An Acylated Kaempferol Glycoside

from Foeniculum vulgare and Foeniculum dulce. Molecules, 7, 245-51.

Soliman, F. M., Shehata. A. H., Khaleel, A. E., Ezzat, S. M., Sleem, A.A. (2002) Comparative Chemical and

Biological Studies of the Volatile Oil of Various Parts of Foeniculum vulgare Mill. and Foeniculum dulce

DC. Growing in Egypt. J. Biomed. Sci., 9,112-132.

Soliman, F. M., Shehata. A. H., Khaleel, A. E., Ezzat, S. M. (2001). Macro- and Micromorphological

Studies of Foeniculum vulgare Mill., and Foeniculum dulce DC. (Fam. Apiaceae) Growing in Egypt, Part I,

The Roots, Rhizomes and Stems. Az. J. Pharm. Sci., 27, 23-40.

Soliman, F. M., Shehata. A. H., Khaleel, A. E., Ezzat, S. M. (2001). Macro- and Micromorphological Studies of Foeniculum vulgare Mill., and Foeniculum dulce DC. (Fam. Apiaceae) Growing in Egypt, Part II, Leaf and Fruit. Az. J. Pharm. Sci., 27, 400-22.

13. Conferences:

1. Farag, M.A., Ezzat, S.M., Salama, M.M., Tadros, M.G., Serya, R.A.T. Anti-acetylcholinesterase activity

potential of Ocimum essential oils - in comparison to its chemical profile via GC/MS and chemometrics.

3rd International Conference and Exhibition Traditional &Alternative Medicine. Birmingham, England.

3-5 August 2015.

2. Ezzat, S.M., Salama, M.M., Seif el-Din, S.H, Salem, M.B., El-Lakkany, N.M., Botros, S.S., Hammam, O.A.,

Saleh, S. Hepatoprotective activity and UPLC-qTOF-PDA-MS profile of the anthocyanin rich extract of

Hibiscus sabdariffa L. calyces. The 4th International Euro-Med Conference of Natural Products (BioNat

IV). Cairo-Sharm, Egypt. 3-7 March 2015.

3. Ezzat, S.M, Kandil, Z.A. Anti-inflammatory, antimicrobial and antioxidant activities of Bergia

ammannioides Roth. extracts and its main constituents.Poster presentation at 14th International

Conference on Oxidative Stress Reduction, Redox Homeostasis and Antioxidants. at Marriott Hotel

Paris Rive Gauche in Paris, France, June 12-13, 2014.

4. Ezzat, S.M, Abdel Motaal, A., Hassan, I., Grigore, A., Albulescu, R., Bauer, R. Aldose

reductase inhibitory activity of the fruits of Balanites aegyptiaca Del. Poster presentation at 2nd

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Cairo University


International Conference on Advanced basic and Applied sciences. Ain Sokhna, Egypt, April

2014

5. Ezzat, S.M, Shabana, M.M., Salama, M.M., Ismail, L.R. Potential anticancer activity of the Fruit Peels of

Solanum melongena L. against hepatocellular carcinoma in vitro and in vivo. Poster presentation at 3rd

World Congress on Cancer Science & Therapy. San Fransisco, California, USA, October,2013.

6. El-Fouly, K., El-Kashoury,S.A., Ezzat, S.M., Abd Rabou, N. “Botanical and genetic characteristics of Tecoma

smiyhii W. Wats. cultivated in Egypt”. Poster presentation at in the 4th International scientific

conference of Faculty of Pharmacy Cairo University, April 24th – 25th , 2013.

7. Ezzat, S.M. Anitioxidant and antimicrobial activities of Bergia ammannioides Roth. (Elatinaceae) in

Humboldt Conference "Pharmaceutical and Biotechnological Therapies". German University in Cairo

(GUC). September, 2012.

8. Hifnawy S.M., Sokkar N.M., Ezzat S.M., Raslan M.M., Salib J.Y., Sleem A.A. "Pharmacognostical and

Biological Study of Mimusops laurifolia (Forssk.) Friis (Sapotaceae)”. Poster presentation at 32nd

International Conference of Pharmaceutical Sciences, 23-25 Dec., 2011, Cairo, Egypt.

9. Abdel Motaal, A.A., Ezza,t S.M., El-Alfy, T.S., El-Askary, H.I. “A Validated HPLC Method for Standardization

of The Most Active Fraction of the Antihyperglycemic Drug Cleome droserifolia using Bioactive Markers.

Oral presentation at 59th International Congress and Annual Meeting of the Society for Medicinal Plant

and Natural Product Research, Antalya, 4-9 September, 2011.

10. A member in the organizing committee of the 2nd Scientific Conference of Faculty of Pharmacy Cairo

University entitled “Quality Assurance In Pharmacy Education” 4/2010.

11. Ezzat, S.M., Abdallah, H.M., Fawzy,G.A. and EL Maraghy, S.A. “Hepatoprotective Constituents of

Torilis radiata Moench. (Apiaceae)”. Poster presentation at 31st International Conference of

Pharmaceutical Sciences, 23-25 Dec., 2008, Cairo, Egypt.

12. Sharing in the first International Conference of “The Center of Quality Assurance and Accreditation,

Cairo University” entitled “Quality Assurance and Accreditation between reality and Ambitions”

15/4/2008.

13. Soliman, F. M., Shehata. A. H., Khaleel, A. E., Ezzat, S. M. A poster presentation entitled “Investigation of

the lipoidal fractions of certain plants belonging to family Asteraceae” in the 30th International

Conference of Pharmaceutical Sciences, 19-21 Dec., 2006, Cairo, Egypt.

14. Soliman, F. M., Shehata. A. H., Khaleel, A. E., Ezzat, S. M. A poster presentation entitled “Botanical and

Biological Studies of Foeniculum vulgare Mill. and Foeniculum dulce DC. Growing in Egypt” in Quality

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Cairo University


Control of Drugs, Vaccines and Natural Products, Seventh Scientific Conference , 1-3 March, 2004,

Cairo, Egypt.

15. Soliman, F. M., Shehata. A. H., Khaleel, A. E., Ezzat, S. M. Two poster presentations entitled “Macro- and

Micromorphological Studies of Foeniculum vulgare Mill., and Foeniculum dulce DC. (Fam. Apiaceae)

Growing in Egypt, Part I, The Roots, Rhizomes and Stem” and “Macro- and Micromorphological Studies

of Foeniculum vulgare Mill., and Foeniculum dulce DC. (Fam. Apiaceae) Growing in Egypt, Part II, The

leaves and fruits” in XXVII Egyptian Conference of Pharmaceutical Sciences, 2-4 Jan., 2001, Cairo, Egypt.

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€¦ · Web viewIsolation of bioactive plant constituents using advanced chromatographic techniques (separation on VLC, and column chromatography using different adsorbent as RP,