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CPAC MBA Collaboration Project

Matt Hallingstad Ejike Anih Siddharth Sureka

mini-update02.23.2011

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Background

Inefficiencies at the CPAC:

• Sample collection from PIs

• Communication with PIs

• Data transfer

• Administrative laboratory management

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Recommendations

Short term:

• Implement effective website communication

• Improve consultation form• Hire Administrative Assistant

Long term:

• Implement IT System to help manage the process

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Short Term Recommendations

Implement effective website communication:

•Website improvements will clearly present CPAC’s value proposition and better manage PI expectations (incl. turn-around times).

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Sample Website Improvement

IMPROVED:Quantification of Compounds; Development Of Quantification Methods CPAC performs quantification of drugs and metabolites with three state-of-the-art instruments:

Applied Biosystems API 3200 LC/MS/MS;Applied Biosystems API 4000 LC/MS/MS; andThermo Scientific HPLC/MS/MS. 

In addition to the HPLC/MS/MS’s, CPAC has access to HPLC systems equipped with UV, fluorescence, and other detectors that may be used for routine analyses. 

ORIGINAL:Access to state-of-the-art instrumentation for quantification of drugs and metabolites is an invaluable resource for all cancer investigators in the IUSCC. The core has two of these instruments (HPLC-MS/MS; API 4000 and API 3200) for drug quantification.  In addition to the two HPLC-MS/MS’s, the core facilities have access to additional HPLC systems (equipped with UV, fluorescent, or other detectors) that may be used for routine analyses. 

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Short Term Recommendations

Improve consultation form:

• The improved consultation form will capture key parameters required for efficient sample intake, and will convey information regarding expected turnaround times.

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Short Term Recommendations

Hire Administrative Assistant:

•Part-time laboratory manager will facilitate intake of samples, coordinate communication with PIs, manage supplies and ordering, thereby allowing lab technicians to focus on core responsibilities.

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Long Term Recommendations

Implement IT System to help manage the process:

• A comprehensive IT system will minimize process and operational inefficiencies by providing easy-to-use interface. It will also facilitate timely communication with PIs, reinforcing CPAC’s position as a state-of-the-art pharmacokinetic Core.